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  • March 2020
  • Technical Note

Intrapreneurship: Leading Innovation Efforts in Established Organizations

By: Karen G. Mills and Annie Dang
“Intrapreneurship” is the use of entrepreneurial management techniques within established companies to create new environments that foster innovation. Mature firms have consistently faced risk of elimination from competitors, shifting consumer preferences, and... View Details
Keywords: Intrapreneurship; Innovation; Corporate Venture Capital; Accelerators; Incubators; Lean Startup; Hypothesis Testing; Business Ventures; Entrepreneurship; Innovation and Invention; Leadership; Framework; Disruption
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Mills, Karen G., and Annie Dang. "Intrapreneurship: Leading Innovation Efforts in Established Organizations." Harvard Business School Technical Note 820-096, March 2020.
  • September 2019 (Revised May 2021)
  • Case

pymetrics: International Expansion

By: John R. Wells and Benjamin Weinstock
In August 2018, pymetrics, a solution offering neuroscience-based recruiting tests, closed a $40 million funding round that valued the business at $160 million. Over 60 companies around the globe were using pymetrics tests in their recruiting process, including... View Details
Keywords: BrainTech; Psychodynamics; Psychology; Hiring Of Employees; Hiring; Strategic Evolution; Strategy And Execution; Startup; Start-up; Startups; Start-ups; Entrepreneur; Bias; Rapid Growth Stage; Recruitment; Selection and Staffing; Strategy; Business Startups; Employment; Growth and Development Strategy; Global Strategy
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Wells, John R., and Benjamin Weinstock. "pymetrics: International Expansion." Harvard Business School Case 720-376, September 2019. (Revised May 2021.)
  • January 2020 (Revised April 2020)
  • Teaching Note

Brandless: Disrupting Consumer Packaged Goods

By: Jill Avery
Brandless, an online direct-to-consumer seller of upscale private-label consumer packaged goods (CPG), offered consumers a limited assortment of values-conscious products delivered directly to their homes with the simplicity of one fixed $3.00 price point that promised... View Details
Keywords: Brand; Brand Management; DTC; Private Label; Groceries; Packaged Food; Personal Care; Startups; Retailing; Amazon; Brands and Branding; Marketing; Marketing Strategy; Business Startups; Disruption; E-commerce; Consumer Products Industry; Retail Industry; United States
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Avery, Jill. "Brandless: Disrupting Consumer Packaged Goods." Harvard Business School Teaching Note 520-058, January 2020. (Revised April 2020.)
  • March 2019
  • Case

DayTwo: Going to Market with Gut Microbiome

By: Ayelet Israeli and David Lane
DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
Keywords: Start-up Growth; Startup; Positioning; Targeting; Go To Market Strategy; B2B2C; B2B Vs. B2C; Health & Wellness; AI; Machine Learning; Female Ceo; Female Protagonist; Science-based; Science And Technology Studies; Ecommerce; Applications; DTC; Direct To Consumer Marketing; US Health Care; "USA,"; Innovation; Pricing; Business Growth; Segmentation; Distribution Channels; Growth and Development Strategy; Business Startups; Science-Based Business; Health; Innovation and Invention; Marketing; Information Technology; Business Growth and Maturation; E-commerce; Applications and Software; Health Industry; Technology Industry; Insurance Industry; Information Technology Industry; Food and Beverage Industry; Israel; United States
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Israeli, Ayelet, and David Lane. "DayTwo: Going to Market with Gut Microbiome." Harvard Business School Case 519-010, March 2019.
  • March 1999 (Revised December 2000)
  • Teaching Note

Pandesic: The Challenges of a New Business Venture (A) and (B) TN

By: Joseph L. Bower and Clark Gilbert
Teaching Note for (9-399-129) and (9-399-130). View Details
Keywords: Business Ventures; Business Startups
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Bower, Joseph L., and Clark Gilbert. "Pandesic: The Challenges of a New Business Venture (A) and (B) TN." Harvard Business School Teaching Note 399-131, March 1999. (Revised December 2000.)
  • May 2017 (Revised October 2017)
  • Case

Hyperloop Transportation Technologies: Building Breakthrough Innovations in Crowd-Powered Ecosystems

By: Lynda M. Applegate, Terri L. Griffith and Ann Majchrzak
Dirk Ahlborn, co-founder and CEO of Hyperloop Transportation Technologies, Inc. (HTT) looks back at the evolving organizational design and community that allows HTT to be crowd-powered. Since the founding in 2013, HTT has dealt with building an organization with less... View Details
Keywords: Collaboration; Crowdsourcing; Entrepreneurial Finance; Innovation; Organizational Design; Startups; Business Startups; Collaborative Innovation and Invention; Entrepreneurship; Finance; Product Development
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Applegate, Lynda M., Terri L. Griffith, and Ann Majchrzak. "Hyperloop Transportation Technologies: Building Breakthrough Innovations in Crowd-Powered Ecosystems." Harvard Business School Case 817-134, May 2017. (Revised October 2017.)
  • March 2017
  • Teaching Note

Hello Alfred: Come Home Happy

By: Joseph B. Fuller and Carin-Isabel Knoop
Teaching Note for HBS No. 316-154. View Details
Keywords: On-demand Economy; Sharing Economy; Technology Startup; Technology; Growth Strategy; Business Startups; Business Growth and Maturation; Entrepreneurship; Mobile and Wireless Technology; Strategic Planning; Service Industry; United States; Boston; Cambridge; New York (city, NY); California
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Fuller, Joseph B., and Carin-Isabel Knoop. "Hello Alfred: Come Home Happy." Harvard Business School Teaching Note 317-099, March 2017.
  • November 2019 (Revised June 2020)
  • Case

Shiseido Acquires Drunk Elephant

By: Jill Avery
On October 7, 2019, the Shiseido Group announced that it would acquire clean skincare brand Drunk Elephant for $845 million, a valuation of 8.5 times sales. Did Shiseido pay too much or too little for this brand asset? How much was the Drunk Elephant brand worth and... View Details
Keywords: Personal Care; Startup; Brand Equity; Brand Valuation; Brand Value; Brand Storytelling; Brand Management; Brands and Branding; Valuation; Marketing; Marketing Strategy; Mergers and Acquisitions; Entrepreneurship; Business Startups; Beauty and Cosmetics Industry; Consumer Products Industry; United States; Japan
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Avery, Jill. "Shiseido Acquires Drunk Elephant." Harvard Business School Case 520-052, November 2019. (Revised June 2020.)
  • October 2009
  • Article

Pioneering Entrepreneur Yoshiko Shinohara on Turning Temporary Work into Big Business in Japan

By: Anthony J. Mayo and Mayuka Yamazaki
Tempstaff's founder, a pioneering Japanese entrepreneur, wondered whether she would go to jail for launching her business. View Details
Keywords: Entrepreneurship; Gender; Business Startups; Employment Industry; Japan
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Mayo, Anthony J., and Mayuka Yamazaki. "Pioneering Entrepreneur Yoshiko Shinohara on Turning Temporary Work into Big Business in Japan." Harvard Business Review 87, no. 10 (October 2009): 30.
  • 2025
  • Working Paper

Too Much, Too Soon? Early Funding, Technological Unconventionality, and Innovation Capabilities

By: Harsh Ketkar and Maria Roche
The availability of financial resources significantly shapes firm innovation outcomes, especially for early-stage, innovation-focused technology firms. However, prior research has provided conflicting findings about this relationship: On the one hand, resource... View Details
Keywords: Startups; Technology Strategy; Novelty; Unconventionality; Resource Constraints; Early Stage Firms; Business Startups; Technological Innovation; Entrepreneurial Finance
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Ketkar, Harsh, and Maria Roche. "Too Much, Too Soon? Early Funding, Technological Unconventionality, and Innovation Capabilities." Harvard Business School Working Paper, No. 25-032, December 2024. (Revised February 2025.)
  • May 2024
  • Case

Naked Wines: The Profit vs. Growth Decision

By: Benjamin C. Esty and Edward A. Meyer
Nick Devlin faced a difficult strategic decision in October 2022. As the CEO of a UK-based subscription business connecting wine drinkers in the US, UK, and Australia with winemakers from around the world (which one journalist called the “Netflix of Wine”), he had to... View Details
Keywords: Profit Vs. Growth; Platform Business; Economies Of Scale; Subscription Business; Wine; Scaling; Racing; Value Creation; Network Effects; Business Startups; Small Business; Financial Management; Financial Strategy; Growth Management; Business Strategy; Competitive Advantage; Expansion; Profit; E-commerce; Growth and Development Strategy; Agriculture and Agribusiness Industry; Food and Beverage Industry; United States; Australia; United Kingdom
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Esty, Benjamin C., and Edward A. Meyer. "Naked Wines: The Profit vs. Growth Decision." Harvard Business School Case 724-462, May 2024.
  • January 2018 (Revised March 2019)
  • Teaching Note

Jumia Nigeria: from Retail to Marketplace (A) and (B)

By: Ramon Casadesus-Masanell and Karen Elterman
Founded in 2012, Jumia Nigeria, a startup effort by Germany-based Rocket Internet, aimed to become an African Amazon. The company entered the nascent market and immediately enjoyed an uptick in consumer spending fueled by the strength of Nigeria’s oil-based economy. By... View Details
Keywords: Retail; Marketplace; Inventory; Ecommerce; Funding; Business Ecosystems; Competition; Business Model; Globalization; Emerging Markets; Expansion; Logistics; E-commerce; Retail Industry; India; Nigeria; Africa
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Casadesus-Masanell, Ramon, and Karen Elterman. "Jumia Nigeria: from Retail to Marketplace (A) and (B)." Harvard Business School Teaching Note 718-467, January 2018. (Revised March 2019.)
  • June 2014 (Revised November 2014)
  • Case

Investing in Online Marketplaces

By: Andrei Hagiu and Hermes Alvarez
Simon Rothman had recently been promoted from executive-in-residence to Partner at esteemed venture capital firm Greylock Partners and placed in charge of managing a $100 million early-stage fund commitment dedicated to online marketplaces. In Greylock's view, 2014 was... View Details
Keywords: Business Models; Competitive Advantage; Entrepreneurship; Internet; Investments; Networks; Technology; Venture Capital
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Hagiu, Andrei, and Hermes Alvarez. "Investing in Online Marketplaces." Harvard Business School Case 714-520, June 2014. (Revised November 2014.)
  • November 2020
  • Teaching Note

DayTwo: Going to Market with Gut Microbiome

By: Ayelet Israeli
Teaching Note for HBS Case No. 519-010. DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals.... View Details
Keywords: Start-up Growth; Startup; Positioning; Targeting; Go To Market Strategy; B2B Vs. B2C; B2B2C; Health & Wellness; AI; Machine Learning; Female Ceo; Female Protagonist; Science-based; Science And Technology Studies; Ecommerce; Applications; DTC; Direct To Consumer Marketing; US Health Care; "USA,"; Innovation; Pricing; Business Growth; Segmentation; Distribution Channels; Growth and Development Strategy; Business Startups; Science-Based Business; Health; Innovation and Invention; Marketing; Information Technology; Business Growth and Maturation; E-commerce; Applications and Software; Health Industry; Technology Industry; Insurance Industry; Information Technology Industry; Food and Beverage Industry; Israel; United States
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Israeli, Ayelet. "DayTwo: Going to Market with Gut Microbiome." Harvard Business School Teaching Note 521-052, November 2020.
  • November 2014
  • Teaching Note

Claritas Genomics

By: Robert F. Higgins and Matthew G. Preble
Dr. Patrice Milos is the first CEO of Claritas Genomics (Claritas) and she faces a number of challenges in scaling the young company. Claritas was formed around a lab spun out from Boston Children's Hospital (BCH) which had performed genomic tests for the hospital. Now... View Details
Keywords: Healthcare; Healthcare Startups; Genetic Testing; Genetics Diagnostics; Spinning Out Hospital Services; Spin-out; Health Care and Treatment; Genetics; Entrepreneurship; Biotechnology Industry; Health Industry; United States
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Higgins, Robert F., and Matthew G. Preble. "Claritas Genomics." Harvard Business School Teaching Note 815-032, November 2014.
  • July 2020
  • Case

Kathy Fish at Procter & Gamble: Navigating Industry Disruption by Disrupting from Within

By: Emily Truelove, Linda A. Hill and Emily Tedards
When Kathy Fish, Procter & Gamble’s Chief Research, Development & Innovation Officer, and a 40-year company veteran, stepped into her role in 2014, she was concerned that the world’s leading consumer packaged goods company had lost its capability to produce a steady... View Details
Keywords: Female Protagonist; Organizational Change; Organizational Behavior; Culture Change; Digital; Innovation; Lean Startup; Experimentation; Metrics; Consumer Packaged Goods (CPG); Leadership; Leading Change; Change Management; Organizational Culture; Organizational Change and Adaptation; Disruption; Innovation and Invention; Digital Transformation
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Truelove, Emily, Linda A. Hill, and Emily Tedards. "Kathy Fish at Procter & Gamble: Navigating Industry Disruption by Disrupting from Within." Harvard Business School Case 421-012, July 2020.
  • February 2019 (Revised November 2021)
  • Case

MoviePass

By: Willy Shih
Mitch Lowe, the CEO of MoviePass, was having trouble convincing people of the viability of the company's business model. The company was building a multi-sided platform and was planning to extract value from increasing traffic to movie theaters through a number of... View Details
Keywords: Start-up; Start-up Growth; Start-ups; Business Model Innovation; Business Model; Innovation and Invention; Multi-Sided Platforms; Business Startups; Planning; Motion Pictures and Video Industry; United States
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Shih, Willy. "MoviePass." Harvard Business School Case 619-052, February 2019. (Revised November 2021.)
  • December 2014 (Revised November 2023)
  • Case

Codecademy: Monetizing a Movement?

By: Jeffrey J. Bussgang and Lisa C. Mazzanti
Codecademy, an open-platform, online community for learning computer programming, launched in 2011. By 2014, the company had raised a total of $12.5 million in funding and was, on many fronts, an overwhelming success. However, there were still no revenues. The founders... View Details
Keywords: Entrepreneurial Management; Startup Management; Technology; Computer Programming; Coding; Online Education; Monetization; Online Communities; Marketplaces; Internet and the Web; Education; Entrepreneurship; Business Startups; Growth and Development Strategy; Technology Industry; Education Industry
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Bussgang, Jeffrey J., and Lisa C. Mazzanti. "Codecademy: Monetizing a Movement?" Harvard Business School Case 815-093, December 2014. (Revised November 2023.)
  • March 2019 (Revised June 2021)
  • Case

HelloSelf: Foundation

By: John R. Wells and Benjamin Weinstock
On January 6, 2019, HelloSelf, a London-based “BrainTech” company, founded a year earlier by Charles Wells, soft launched. The proposition was simply to help its members “Be your Best Self.” The company provided its registered members with access to a clinical... View Details
Keywords: Startup; Start-up; Startup Management; Startup Marketing; Startups; Start-ups; BrainTech; Marketing Research; Strategic Decision Making; Strategy Development; Strategy Dynamics; Neuroscience; Cognition; Cognitive Psychology; Health & Wellness; Health Care; Health Care Reform; Health Care Outcomes; Self-awareness; Mental Health; Wellbeing; Wellness; Funding; Equity Financing; Raising Capital; Synergies; Team Building; National Health Insurance; Artificial Intelligence; MVP; Business Startups; Health; Health Care and Treatment; Management; Well-being; Marketing Channels; Decision Making; Strategy; Technology; United Kingdom; London
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Wells, John R., and Benjamin Weinstock. "HelloSelf: Foundation." Harvard Business School Case 719-492, March 2019. (Revised June 2021.)
  • April 2014 (Revised January 2015)
  • Background Note

Note on Mobile Healthcare

By: John A. Quelch and Margaret L. Rodriguez
Delivering health care to the global population was a challenge. Health care costs accounted for ten percent of world GDP by 2013. In the U.S., health care costs were expected to top $3.1 trillion in 2014. New technologies, shortages of trained personnel and... View Details
Keywords: Health Care; Mobile; Mobile App; Public Health; Startups; Hardware; Software; Telemedicine; Global; Medical Devices; Medical Services; Medical Solutions; Entrepreneurs; Government And Business; Technological Change; Health Care and Treatment; Entrepreneurship; Government and Politics; Technological Innovation; Applications and Software; Information Infrastructure; Health Industry; Technology Industry
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Quelch, John A., and Margaret L. Rodriguez. "Note on Mobile Healthcare." Harvard Business School Background Note 514-122, April 2014. (Revised January 2015.)
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