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- July 2025
- Case
Insilico’s Rentosertib Dilemma: A Star in the Pipeline?
By: Michael Lingzhi Li, Brian Mao Fu and Billy Chan
In 2024, the AI biotech firm Insilico Medicine faced a pivotal decision about its new drug, Rentosertib. Discovered and designed using artificial intelligence to treat a lung disease, Rentosertib had successfully advanced to Phase II trials — a first in global... View Details
- July 2025
- Teaching Note
Silicon Valley Bank: Gone in 36 Hours
Teaching Note for HBS Case No. 125-094. View Details
- July 2025
- Article
On the Economic Origins of Concerns Over Women’s Chastity
By: Anke Becker
This paper studies the origins and function of customs and norms that intend to keep women from being promiscuous. Using large-scale survey data from more than 100 countries, I test the anthropological theory that a particular form of preindustrial... View Details
- 2025
- Working Paper
Sovereign Default and the Decline in Interest Rates
By: Max Miller, James D. Paron and Jessica Wachter
Sovereign debt yields have declined dramatically over the last half-century. Standard explanations, including aging populations and increases in asset demand from abroad, encounter difficulties when confronted with the full range of evidence. We propose an explanation... View Details
- June 2025
- Case
From Single Stock to Diversified Portfolio: Mastercard Foundation's $42 Billion Asset Management Launch
By: Luis M. Viceira and Justin Cohen
This case examines the decision of the Mastercard Foundation in 2023 to divest its holdings of Mastercard stock, its only asset since inception in 2006 and worth $42 billion in early 2024, and to invest the proceeds in a newly designed diversified portfolio. To this... View Details
- June 2025
- Supplement
Transforming a Titan (C)
By: George Serafeim and Lena Duchene
Three years in his tenure as CEO, Cobuz must decide whether to launch a more than €500 million carbon-capture-and-storage facility. The project—Europe’s largest planned CCS installation—would cut almost 20% of group emissions and unlock a €234 million EU Innovation... View Details
- June 4, 2025
- Editorial
Employee Stress Is a Business Risk—Not an HR Problem
By: Marion Chomse, Lydia Roos, Reeva Misra and Ashley Whillans
Workplace stress, on the rise for decades, has been treated by many organizations as a personal issue instead of a business-critical risk that merits executive oversight. This is likely due in part to the fact that companies have not effectively quantified and tracked... View Details
- 2025
- Working Paper
Pushing the Envelope: The Effects of Salary Negotiations
By: Zoë B. Cullen, Bobak Pakzad-Hurson and Ricardo Perez-Truglia
Salary negotiations are a widespread phenomenon that can shape key labor market outcomes, such as welfare and inequality. We provide novel empirical and theoretical insights into the causes and consequences of salary negotiations. We conducted two field experiments... View Details
- June 2025
- Article
Unregulated Emotional Risks of AI Wellness Apps
By: Julian De Freitas and Glenn Cohen
We propose that AI-driven wellness apps powered by large language models can foster extreme emotional attachments and dependencies akin to human relationships—posing risks like ambiguous loss and dysfunctional dependence—that challenge current regulatory frameworks and... View Details
- June 2025
- Case
Vail Resorts: Responding to Activist Pressure (A)
By: Benjamin C. Esty and Edward A. Meyer
On January 27, 2025, the head of a relatively small hedge fund named Late Apex Partners sent a highly critical letter to the board of directors of Vail Resorts, the world’s largest ski resort operator. In his letter, and the 88-slide presentation that accompanied his... View Details
Keywords: Corporate Finance; Capital Budgeting; Corporate Governance; Competitive Advantage; Competitive Strategy; Leading Change; Valuation; Investment Activism; Climate Change; Management Succession; Financial Management; Risk Management; Business and Shareholder Relations; Entertainment and Recreation Industry; Entertainment and Recreation Industry; Entertainment and Recreation Industry; United States; Australia; Canada
- June 2025
- Article
What Board-level Control Mechanisms Changed in Banks Following the 2008 Financial Crisis? A Descriptive Study
By: Shelly Li, Shivram Rajgopal, Suraj Srinivasan and Yu Ting Forester Wong
Following the 2008 financial crisis, the Financial Crisis Inquiry Commission (FCIC) identified major shortcomings in bank board governance, contributing to systemic risk management failures. This study adapts a management control framework and empirically examines... View Details
- May 2025
- Teaching Note
From oneworld to a New World? LATAM’s High-Stakes Alliance Dilemma
By: Juan Alcacer and Valentina Tarzijan
As global alliances evolve and regulatory barriers mount, LATAM Airlines must reassess the strategic logic of partnerships. In 2019, Delta Air Lines proposed a $1.9 billion investment and deeper cooperation via a Joint Business Agreement, prompting LATAM to evaluate... View Details
- May 2025
- Case
From oneworld to a New World? LATAM’s High-Stakes Alliance Dilemma
By: Juan Alcacer and Valentina Tarzijan
As global alliances evolve and regulatory barriers mount, LATAM Airlines must reassess the strategic logic of partnerships. In 2019, Delta Air Lines proposed a $1.9 billion investment and deeper cooperation via a Joint Business Agreement, prompting LATAM to evaluate... View Details
- May 2025
- Article
Imagining the Future: Memory, Simulation and Beliefs
By: Pedro Bordalo, Giovanni Burro, Katherine B. Coffman, Nicola Gennaioli and Andrei Shleifer
How do people form beliefs about novel risks, with which they have little or no experience? Motivated by survey data on beliefs about Covid we collected in 2020, we build a model based on the psychology of selective memory. When a person thinks about an event,... View Details
- 2025
- Working Paper
The Limits of Insurance Demand and the Growing Protection Gap
By: Parinitha Sastry, Tess Scharlemann, Ishita Sen and Ana-Maria Tenekedjieva
In a world with rising risk, how much are U.S. households willing to pay for homeowners insurance, and what does their demand imply for the future of insurance markets? We provide the first estimates of household willingness to pay for homeowners insurance and the... View Details
- May 2025
- Case
The Micro-Family Office: Aamir Rehman
By: Lauren Cohen and Sophia Pan
With a successful career and strong academic credentials, Aamir Rehman sought to design a life grounded in autonomy. For him, this meant serving on boards, continuing his professorship, and ensuring a secure and comfortable life for his family. While he didn’t possess... View Details
Keywords: Family Office; Family And Friends; Trends And Opportunities; Wealth Management; Family Business; Financial Strategy; Personal Finance; Investment Portfolio; Private Equity; Organizational Design; Family and Family Relationships; Happiness; Satisfaction; Balance and Stability; Human Capital; Compensation and Benefits; Economy; Trends; Business Model; Asset Management; Financial Management; New Jersey; United States
- April 2025
- Background Note
Climate Change Adaptation with Artificial Intelligence and Machine Learning
By: Michael W. Toffel and Nabig Chaudhry
Artificial Intelligence (AI) and machine learning (ML) have emerged as powerful tools to address climate change. This note summarizes a wide range of the uses of AI/ML to drive climate change adaptation and resilience, the measures organizations and governments are... View Details
- April 2025
- Case
Japan Industrial Partners Powers the Leveraged Buyout of Toshiba
By: Brian K. Baik, Joseph Pacelli and James Barnett
The case explores Japan Industrial Partners (JIP) $14 billion takeover of Toshiba Corporation (Toshiba). JIP was a private equity firm that took over the troubled electronics corporation in late 2023. The deal, which had been labeled one of the largest leveraged... View Details
Keywords: International Accounting; Borrowing and Debt; Management Analysis, Tools, and Techniques; Ownership; Risk and Uncertainty; Strategy; Valuation; Leveraged Buyouts; Restructuring; Capital Structure; Cost of Capital; Private Equity; Bids and Bidding; Accounting Industry; Electronics Industry; Energy Industry; Manufacturing Industry; Semiconductor Industry; Asia; Japan
- April 2025
- Teaching Note
ZEISS: Commercializing Science
By: Maria P. Roche
Teaching Note for HBS Case No. 725-359. View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
- 2025
- Report
High Stakes: A Framework for Geopolitical Risk Management
By: Meg Rithmire and David Fagan
This report provides a data-based assessment of how U.S. companies perceive geopolitical risk and articulates a recommended decision-making process and framework to manage such risk. The research reflected in the report indicates that various concerns related to China... View Details