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- 2023
- Working Paper
Leadership and the Value of Persistence
By: James J. Anton, Alan Jaske and Dennis Yao
Consider a leader’s decision whether to persist with an unsuccessful R&D project
or to terminate the project in favor of a new project with an uncertain value. How
does that decision affect the effort exerted by the manager assigned to the project? To
study this... View Details
- September 2022
- Article
Find and Replace: R&D Investment Following the Erosion of Existing Products
By: Joshua L. Krieger, Xuelin Li and Richard T. Thakor
How do innovative firms react when existing products experience negative shocks? We explore this question with detailed project-level data from drug development firms. Using FDA Public Health Advisories as idiosyncratic negative shocks to approved drugs, we first... View Details
Keywords: R&D Investments; Drug Development; Product Shocks; M&A; Biopharmaceutical Industry; FDA; System Shocks; Research and Development; Investment; Decision Making; Pharmaceutical Industry
Krieger, Joshua L., Xuelin Li, and Richard T. Thakor. "Find and Replace: R&D Investment Following the Erosion of Existing Products." Management Science 68, no. 9 (September 2022): 6552–6571.
- Summer 2021
- Article
The World Management Survey at 18: lessons and the way forward
By: Daniela Scur, Raffaella Sadun, John Van Reenen, Renata Lemos and Nicholas Bloom
Understanding how differences in management ‘best practices’ affect organizational outcomes has been a focus of both theoretical and empirical work in the fields of management, sociology, economics, and public policy. The World Management Survey (WMS) project was born... View Details
Keywords: Firm Objectives, Organization, And Behavior; Business Economics; Choice Of Technology; Management Of Technological Innovation And R&D; Technological Change: Choices And Consequences; Management Practices and Processes
Scur, Daniela, Raffaella Sadun, John Van Reenen, Renata Lemos, and Nicholas Bloom. "The World Management Survey at 18: lessons and the way forward." Oxford Review of Economic Policy 37, no. 2 (Summer 2021): 231–258.
- March 2018 (Revised September 2023)
- Case
X: The Foghorn Decision
In February 2016, Kathy Hannun—a project leader at X, Alphabet Inc.'s so-called "moonshot factory"—had to prepare a recommendation for the senior leadership of X regarding the future of Foghorn, a project she was leading to develop a carbon-neutral process for... View Details
Keywords: Innovation; R&D Project Management; Radical Innovation; Clean Technology; Innovation and Management; Technological Innovation; Energy; Research and Development; Projects; Management; Decision Choices and Conditions; Technology Industry; Energy Industry; Green Technology Industry; California
Huckman, Robert S., Karim R. Lakhani, and Kyle R. Myers. "X: The Foghorn Decision." Harvard Business School Case 618-060, March 2018. (Revised September 2023.)
- Article
Lessons From Hollywood: A New Approach To Funding R&D
By: Gary P. Pisano and Andrew W. Lo
Companies find it increasingly difficult to justify long-term, risky R&D investments—particularly in science-based fields such as biotechnology, advanced materials, and energy. We argue in this article that the traditional venture model has limits for such investments... View Details
Keywords: Financial Innovation; Financial Strategy; Project Management; R&D; Start-up; Innovation Strategy; Business Model; Research and Development; Financial Management; Risk Management; Strategy
Pisano, Gary P., and Andrew W. Lo. "Lessons From Hollywood: A New Approach To Funding R&D." MIT Sloan Management Review 57, no. 2 (Winter 2016): 47–54.
- November 2016
- Case
Anthony Starks at InSiL Therapeutics (A)
By: Gary Pisano and Vicki Sato
When Bruce Wayne hired Anthony Starks, he thought he had hit a home run by getting the most brilliant and passionate scientist-leader in the field to be his CSO. But a few months in, Wayne and Starks begin to clash over crucial forward-looking decisions about the... View Details
Keywords: Biotech; Silicon; Managing Innovation; Management Challenges; Managing People; Managing Organization; R&D; R&D Project Management; Platform; Venture Capital; Drug Discovery; management; Biotechnology Industry; California
Pisano, Gary, and Vicki Sato. "Anthony Starks at InSiL Therapeutics (A)." Harvard Business School Case 617-029, November 2016.
- November 2016 (Revised December 2016)
- Supplement
Anthony Starks at InSiL Therapeutics (B)
By: Vicki Sato and Gary Pisano
This case accompanies the (A) case from Anthony Starks's perspective. View Details
Keywords: Biotech; Management Challenges; R&D; R&D Project Management; Management; Biotechnology Industry; California
Sato, Vicki, and Gary Pisano. "Anthony Starks at InSiL Therapeutics (B)." Harvard Business School Supplement 617-030, November 2016. (Revised December 2016.)
- October 2015
- Article
Managing the Performance Tradeoffs from Partner Integration: Implications of Contract Choice in R&D Projects
By: Alan MacCormack and Anant Mishra
Formal contracts represent an important governance instrument with which firms exercise control of and compensate partners in R&D projects. The specific type of contract used, however, can vary significantly across projects. In some, firms govern partnering... View Details
Keywords: ""Partner Integration; Contract Choice; R&D Project Management; Relational Contracts; Partnering Performance; Research and Development; Projects; Partners and Partnerships; Performance; Contracts
MacCormack, Alan, and Anant Mishra. "Managing the Performance Tradeoffs from Partner Integration: Implications of Contract Choice in R&D Projects." Production and Operations Management 24, no. 10 (October 2015): 1552–1569.
- January 2015
- Article
Collaboration in Multi-Partner R&D Projects: The Impact of Partnering Scale and Scope
By: Anant Mishra, Aravind Chandrasekaran and Alan MacCormack
How can firms design collaboration structures for effective performance in R&D projects that involve multiple partners? To address this question, we examine the theoretical underpinnings of collaboration structures in multi-partner R&D projects—i.e., the scale and the... View Details
Keywords: Multi-Partner R&D Projects; Empirical Research; New Development; Collaboration Structures; Partnering Scale And Scope; Partners and Partnerships; Infrastructure; Performance Capacity; Research and Development; Collaborative Innovation and Invention
Mishra, Anant, Aravind Chandrasekaran, and Alan MacCormack. "Collaboration in Multi-Partner R&D Projects: The Impact of Partnering Scale and Scope." Journal of Operations Management 33-34 (January 2015): 1–14.
- June 2012 (Revised July 2012)
- Case
Business-driven Research at IBM Research India
By: Willy Shih, Margaret Pierson, Pankaj Agarwal, Diego Medicina and Juan Prajogo
What is the right mix between business-driven and pure research? This case considers the question in the setting of IBM Research India, where a management push for balance between exploratory research and the fulfillment of business needs meets some resistance from... View Details
Keywords: R&D; Computer Services Industries; IT R&D; Internet; Web-enabled Application; Technological Planning; Emerging Technologies; Information Technology; Internet and the Web; Research and Development; Projects; Practice; India
Shih, Willy, Margaret Pierson, Pankaj Agarwal, Diego Medicina, and Juan Prajogo. "Business-driven Research at IBM Research India ." Harvard Business School Case 612-076, June 2012. (Revised July 2012.)
- April 2012
- Case
Bella Healthcare India
By: Dorothy Leonard and Sunru Yong
Bella Healthcare India was originally established in Bangalore as a low-cost manufacturing facility for a U.S.-based cardiology equipment developer. Under country manager Joseph Cherian it evolved considerably, developing its own research and development capabilities.... View Details
Keywords: India; Productivity; Organizational Development; International Business; R&D; Cross-cultural Relations; Medical Equipment & Devices; Joint Ventures; Medical Specialties; Research and Development; Product Development; Organizational Change and Adaptation; Strategy; Decision Choices and Conditions; Health Care and Treatment; Product Launch; Failure; Cross-Cultural and Cross-Border Issues; Medical Devices and Supplies Industry; Bangalore
Leonard, Dorothy, and Sunru Yong. "Bella Healthcare India." Harvard Business School Brief Case 124-440, April 2012.