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      • Faculty Publications  (66)

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      • January 2025
      • Case

      Summer Health: Raising an AI-First Company?

      By: Jeffrey J. Bussgang, Sarah Mehta and Maxim Pike Harrell
      In October 2023, Summer Health CEO Ellen DaSilva arrived at a defining juncture for her pediatric telehealth startup. Founded in 2021, Summer Health offered parents rapid access to licensed pediatricians via text message. DaSilva, an experienced telehealth executive,... View Details
      Keywords: AI and Machine Learning; Technology Adoption; Entrepreneurship; Leadership; Business Startups; Health Care and Treatment; Business Strategy; Health Industry; Telecommunications Industry; United States
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      Bussgang, Jeffrey J., Sarah Mehta, and Maxim Pike Harrell. "Summer Health: Raising an AI-First Company?" Harvard Business School Case 825-083, January 2025.
      • January 2025
      • Case

      A Tiger in the Tank: Exxon Sues Investors

      By: Clayton S. Rose, Sarah Sasso and James Weber
      In June 2024, investors were trying to make sense of ExxonMobil’s (Exxon) lawsuit against two impact investors, Arjuna Capital (Arjuna) and Follow This, that had just been dismissed by the U.S. District Court of Northern Texas. Exxon’s suit challenged the rights of two... View Details
      Keywords: Disruption; Talent and Talent Management; Customer Satisfaction; Decision Making; Demographics; Ethics; Corporate Accountability; Employees; Recruitment; Retention; Leadership; Crisis Management; Risk Management; Corporate Social Responsibility and Impact; Mission and Purpose; Organizational Change and Adaptation; Civil Society or Community; Social Issues; Adaptation; Investment Activism; Lawsuits and Litigation; Business and Shareholder Relations; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; United States; Netherlands; Norway
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      Rose, Clayton S., Sarah Sasso, and James Weber. "A Tiger in the Tank: Exxon Sues Investors." Harvard Business School Case 325-015, January 2025.
      • October 10, 2024
      • Article

      Characteristics of Creative Individuals: An Umbrella Review Protocol

      By: Alex Thabane, Tyler McKechnie, Phillip Staibano, Goran Calic, Colin Kruse, Jason W. Busse, Samee Parpia and Mohit Bhandari
      The properties of creative products–novelty and usefulness–are generally agreed upon by researchers. Yet, consensus is lacking on which personal and environmental factors contribute to an individual’s creative potential, or to what extent. substantial research work has... View Details
      Keywords: Creativity; Medical Specialties; Personal Characteristics; Health Industry; Canada
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      Thabane, Alex, Tyler McKechnie, Phillip Staibano, Goran Calic, Colin Kruse, Jason W. Busse, Samee Parpia, and Mohit Bhandari. "Characteristics of Creative Individuals: An Umbrella Review Protocol." PLoS ONE 19, no. 10 (October 10, 2024).
      • July 2024
      • Case

      Roja Garimella: Developing a Founder's Judgment

      By: Reza Satchu and Patrick Sanguineti
      Roja Garimella’s path to becoming a founder was anything but straight. Setting her sights on a career in medicine since childhood, she committed to medical school with her acceptance to college. And yet, throughout her studies, she continually explored alternative... View Details
      Keywords: Entrepreneurship; Personal Development and Career; Entrepreneurial Finance; Business Startups; Judgments; Financial Services Industry; Health Industry
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      Satchu, Reza, and Patrick Sanguineti. "Roja Garimella: Developing a Founder's Judgment." Harvard Business School Case 825-006, July 2024.
      • July–August 2024
      • Article

      The Middle Path to Innovation

      By: Regina E. Herzlinger, Duke Rohlen, Ben Creo and Will Kynes
      Too many companies are failing to innovate. One reason, say the authors, is the polarized approach companies take to innovation. At one end of the spectrum, corporate R&D efforts tend to focus on product refreshes and incremental line upgrades that generate modest... View Details
      Keywords: Innovation Strategy; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., Duke Rohlen, Ben Creo, and Will Kynes. "The Middle Path to Innovation." Harvard Business Review 102, no. 4 (July–August 2024): 134–145.
      • June 2024
      • Supplement

      Legacy Partners (A)

      By: Richard S. Ruback and Royce Yudkoff
      Instructors should consider the timing of making videos available to students, as they may reveal key case details.

      Stephen Holbrook and Austin Pulsipher (both HBS '19) had been leading Nutrishare since acquiring the company six months earlier in mid-2021.... View Details
      Keywords: Acquisition; Small Business; Cost vs Benefits; Decisions; Corporate Entrepreneurship; Leadership Style; Leading Change; Business or Company Management; Problems and Challenges; Health Care and Treatment; Health Disorders; Medical Specialties; Nutrition; Supply Chain Management; Growth Management; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; United States; California
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      Ruback, Richard S., and Royce Yudkoff. "Legacy Partners (A)." Harvard Business School Multimedia/Video Supplement 224-725, June 2024.
      • June 2024
      • Supplement

      Legacy Partners (B)

      By: Richard S. Ruback and Royce Yudkoff
      Pre-abstract: Instructors should consider the timing of making videos available to students, as they may reveal key case details.

      Abstract: Stephen Holbrook and Austin Pulsipher (both HBS '19) had been leading Nutrishare since acquiring the company six... View Details
      Keywords: Acquisition; Small Business; Cost vs Benefits; Decisions; Business Education; Corporate Entrepreneurship; Leadership Style; Leading Change; Business or Company Management; Problems and Challenges; Health Care and Treatment; Health Disorders; Medical Specialties; Nutrition; Supply Chain Management; Growth Management; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; United States; California
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      Ruback, Richard S., and Royce Yudkoff. "Legacy Partners (B)." Harvard Business School Multimedia/Video Supplement 224-726, June 2024.
      • May 2024
      • Article

      The Health Risks of Generative AI-Based Wellness Apps

      By: Julian De Freitas and G. Cohen
      Artifcial intelligence (AI)-enabled chatbots are increasingly being used to help people manage their mental health. Chatbots for mental health and particularly ‘wellness’ applications currently exist in a regulatory ‘gray area’. Indeed, most generative AI-powered... View Details
      Keywords: AI and Machine Learning; Well-being; Governing Rules, Regulations, and Reforms; Applications and Software
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      De Freitas, Julian, and G. Cohen. "The Health Risks of Generative AI-Based Wellness Apps." Nature Medicine 30, no. 5 (May 2024): 1269–1275.
      • March 2024 (Revised April 2024)
      • Case

      Angel City Football Club: Scoring a New Model

      By: Jeffrey F. Rayport, Jennifer Fonstad and Nicole Tempest Keller
      In January 2024, Kara Nortman, Julie Uhrman, and Natalie Portman, the founders of Angel City Football Club (ACFC) were developing the club’s first three-year strategic plan. Founded in 2020, ACFC had a star-studded investor group, including Portman and celebrities such... View Details
      Keywords: Sports; Entertainment; Entrepreneurship; Brands and Branding; Venture Capital; Business Model; Corporate Strategy; Digital Marketing; Sports Industry; Entertainment and Recreation Industry; United States; California; Los Angeles
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      Rayport, Jeffrey F., Jennifer Fonstad, and Nicole Tempest Keller. "Angel City Football Club: Scoring a New Model." Harvard Business School Case 824-192, March 2024. (Revised April 2024.)
      • February 2024
      • Article

      Representation and Extrapolation: Evidence from Clinical Trials

      By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
      This article examines the consequences and causes of low enrollment of Black patients in clinical trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is more relevant for decision-making by physicians and patients when it... View Details
      Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry
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      Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." Quarterly Journal of Economics 139, no. 1 (February 2024): 575–635.
      • 2023
      • Article

      Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset

      By: Junling Liu, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu and Michael Lingzhi Li
      Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address this gap, we introduce CMExam,... View Details
      Keywords: Large Language Model; AI and Machine Learning; Analytics and Data Science; Health Industry
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      Liu, Junling, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu, and Michael Lingzhi Li. "Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset." Conference on Neural Information Processing Systems (NeurIPS), Datasets and Benchmarks Track 36 (2023).
      • March 2023 (Revised March 2025)
      • Case

      Close Concerns: Diabetes Research and Advocacy

      By: Regina Herzlinger and Brian L. Walker
      Diagnosed with diabetes at the age of 18, Kelly Close understood the importance of balancing consistency and iteration. This principle had also informed her professional work, which started with a rapid promotion from financial analyst at Goldman Sachs to an analyst... View Details
      Keywords: Diabetes; Health; Health Care; Health Care And Treatment; Health Care Outcomes; Health Care Industry; Knowledge Dissemination; Outcome or Result; Equality and Inequality; Business Model; Entrepreneurship
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      Herzlinger, Regina, and Brian L. Walker. "Close Concerns: Diabetes Research and Advocacy." Harvard Business School Case 323-047, March 2023. (Revised March 2025.)
      • November 2022
      • Case

      Ajax Health: A New Model for Medical Technology Innovation

      By: Regina E. Herzlinger and Ben Creo
      This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets... View Details
      Keywords: Business Startups; Success; Innovation Strategy; Mergers and Acquisitions; Market Entry and Exit; Financial Strategy; Business Model; Partners and Partnerships; Entrepreneurship; Private Equity; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
      • April 12, 2022
      • Article

      Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States

      By: Estee Y. Cramer, Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li and et al.
      Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models... View Details
      Keywords: COVID-19; Forecasting and Prediction; Health Pandemics; Mathematical Methods; Partners and Partnerships
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      Cramer, Estee Y., Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li, and et al. "Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States." e2113561119. Proceedings of the National Academy of Sciences 119, no. 15 (April 12, 2022). (See full author list here.)
      • Article

      Eliminating Unintended Bias in Personalized Policies Using Bias-Eliminating Adapted Trees (BEAT)

      By: Eva Ascarza and Ayelet Israeli

      An inherent risk of algorithmic personalization is disproportionate targeting of individuals from certain groups (or demographic characteristics such as gender or race), even when the decision maker does not intend to discriminate based on those “protected”... View Details

      Keywords: Algorithm Bias; Personalization; Targeting; Generalized Random Forests (GRF); Discrimination; Customization and Personalization; Decision Making; Fairness; Mathematical Methods
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      Ascarza, Eva, and Ayelet Israeli. "Eliminating Unintended Bias in Personalized Policies Using Bias-Eliminating Adapted Trees (BEAT)." e2115126119. Proceedings of the National Academy of Sciences 119, no. 11 (March 8, 2022).
      • January 2022
      • Case

      Somatus: Value-Based Kidney Care (A)

      By: Ariel D. Stern, Robert S. Huckman and Sarah Mehta
      When Dr. Ikenna Okezie founded Somatus, a value-based kidney care provider, his goal had been nothing short of transforming kidney care delivery in the United States. Rather than relying on dialysis, a costly and intensive treatment for late-stage kidney disease, the... View Details
      Keywords: Business Startups; Disruption; Entrepreneurship; Health; Health Care and Treatment; Health Disorders; Medical Specialties; Innovation and Invention; Disruptive Innovation; Management; Strategy; Business Strategy; Value; Value Creation; Health Industry; United States; Virginia
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      Stern, Ariel D., Robert S. Huckman, and Sarah Mehta. "Somatus: Value-Based Kidney Care (A)." Harvard Business School Case 622-009, January 2022.
      • May 2021
      • Case

      Inclusive Innovation at Mass General Brigham

      By: Katherine Baldiga Coffman and Olivia Hull
      Massachusetts General Brigham (MGB) Chief Innovation Officer Christopher Coburn had overseen a period of exciting transformation and growth in healthcare innovation at MGB. In November 2019, the health system was the largest recipient of National Institutes of Health... View Details
      Keywords: Inclusion; Innovation; Invention; Gender; Business Startups; Investment Funds; Private Equity; Health Care and Treatment; Innovation Strategy; Technological Innovation; Intellectual Property; Copyright; Patents; Research; Research and Development; Diversification; Technology; Health Industry; Massachusetts; Boston
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      Coffman, Katherine Baldiga, and Olivia Hull. "Inclusive Innovation at Mass General Brigham." Harvard Business School Case 921-006, May 2021.
      • May 2021
      • Article

      Choice Architecture in Physician–patient Communication: A Mixed-methods Assessment of Physicians' Competency

      By: J. Hart, K. Yadav, S. Szymanski, A. Summer, A. Tannenbaum, J. Zlatev, D. Daniels and S.D. Halpern
      Background: Clinicians’ use of choice architecture, or how they present options, systematically influences the choices made by patients and their surrogate decision makers. However, clinicians may incompletely understand this influence.... View Details
      Keywords: Choice Architecture; Health Care and Treatment; Interpersonal Communication; Decision Choices and Conditions; Competency and Skills
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      Hart, J., K. Yadav, S. Szymanski, A. Summer, A. Tannenbaum, J. Zlatev, D. Daniels, and S.D. Halpern. "Choice Architecture in Physician–patient Communication: A Mixed-methods Assessment of Physicians' Competency." BMJ Quality & Safety 30, no. 5 (May 2021).
      • May 2021
      • Article

      Making Doctors Effective Managers and Leaders: A Matter of Health and Well-Being

      By: Lisa Rotenstein, Robert S. Huckman and Christine K. Cassel
      The COVID-19 crisis has forced physicians to make daily decisions that require knowledge and skills they did not acquire as part of their biomedical training. Physicians are being called upon to be both managers—able to set processes and structures—and leaders—capable... View Details
      Keywords: Health Care and Treatment; Management; Leadership; Health Pandemics; Health Industry
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      Rotenstein, Lisa, Robert S. Huckman, and Christine K. Cassel. "Making Doctors Effective Managers and Leaders: A Matter of Health and Well-Being." Academic Medicine 96, no. 5 (May 2021).
      • April 2021
      • Article

      Today's Surgeon Compensation Models Fall Short: Aligning Incentives to Create More Equitable and Value-based Compensation Models

      By: Susanna Gallani, Mary Witkowski, Lauren Haskins, Haley Jeffcoat, Vinita Mujumdar and Frank Opelka
      Modern medicine is undergoing a transformation that involves innovative surgical approaches, increased medical treatment options, clinical care pathways that require collaboration beyond hospital walls, and health data captured by electronic health records and other... View Details
      Keywords: Physician Compensation; Surgeons; Health Care and Treatment; Business Model; Compensation and Benefits
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      Gallani, Susanna, Mary Witkowski, Lauren Haskins, Haley Jeffcoat, Vinita Mujumdar, and Frank Opelka. "Today's Surgeon Compensation Models Fall Short: Aligning Incentives to Create More Equitable and Value-based Compensation Models." Bulletin of the American College of Surgeons 106, no. 4 (April 2021): 33–39.
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