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- September 2023 (Revised April 2024)
- Case
Atomwise: Strategic Opportunities in AI for Pharma
By: Satish Tadikonda
Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural... View Details
Keywords: Business Model; Business Startups; AI and Machine Learning; Science-Based Business; Technological Innovation; Biotechnology Industry; Pharmaceutical Industry
Tadikonda, Satish. "Atomwise: Strategic Opportunities in AI for Pharma." Harvard Business School Case 824-043, September 2023. (Revised April 2024.)
- July 2023 (Revised July 2023)
- Background Note
Generative AI Value Chain
By: Andy Wu and Matt Higgins
Generative AI refers to a type of artificial intelligence (AI) that can create new content (e.g., text, image, or audio) in response to a prompt from a user. ChatGPT, Bard, and Claude are examples of text generating AIs, and DALL-E, Midjourney, and Stable Diffusion are... View Details
Keywords: AI; Artificial Intelligence; Model; Hardware; Data Centers; AI and Machine Learning; Applications and Software; Analytics and Data Science; Value
Wu, Andy, and Matt Higgins. "Generative AI Value Chain." Harvard Business School Background Note 724-355, July 2023. (Revised July 2023.)
- September 15, 2021
- Article
Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map
By: Andrea Blasco, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani and Aravind Subramanian
A recurring problem in biomedical research is how to isolate signals of distinct populations (cell types, tissues, and genes) from composite measures obtained by a single analyte or sensor. Existing computational deconvolution approaches work well in many specific... View Details
Keywords: Deconvolution; Methods; Open Innovation Competition; Genomics; Research; Innovation and Invention
Blasco, Andrea, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani, and Aravind Subramanian. "Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map." Bioinformatics 37, no. 18 (September 15, 2021).
- April 2021
- Case
Codecademy: Where to Next?
By: Jeffrey F. Rayport, Max Mailman and Sarah Ascherman
In March 2020, Zach Sims, co-founder and CEO of online education platform Codecademy, prepared for a meeting with his Chief of Staff Kunal Ahuja to discuss the company’s goals. Codecademy billed itself as the largest online resource for computer science literacy and... View Details
Keywords: Monetization Strategy; Business Model; Change Management; Venture Capital; Leading Change; Growth and Development Strategy; Growth Management; Management Teams; Marketing Channels; Product Marketing; Network Effects; Product Development; Organizational Change and Adaptation; Strategic Planning; Internet and the Web; Digital Platforms; United States
Rayport, Jeffrey F., Max Mailman, and Sarah Ascherman. "Codecademy: Where to Next?" Harvard Business School Case 821-093, April 2021.
- 2021
- Working Paper
First Law of Motion: Influencer Video Advertising on TikTok
By: Jeremy Yang, Juanjuan Zhang and Yuhan Zhang
This paper engineers an intuitive feature that is predictive of the causal effect of influencer video advertising on product sales. We propose the concept of m-score, a summary statistic that captures the extent to which a product is advertised in the most engaging... View Details
Keywords: Influencer Advertising; Video Advertising; Computer Vision; Machine Learning; Advertising; Online Technology
Yang, Jeremy, Juanjuan Zhang, and Yuhan Zhang. "First Law of Motion: Influencer Video Advertising on TikTok." Working Paper, March 2021.
- February 2021
- Article
Platform Diffusion at Temporary Gatherings: Social Coordination and Ecosystem Emergence
By: Tommy Pan Fang, Andy Wu and David R. Clough
Software platforms create value by cultivating an ecosystem of complementary products and services. Existing explanations for how a prospective complementor chooses platforms to join assume the complementor has rich information about the range of available platforms.... View Details
Keywords: Innovation Ecosystems; Technology Diffusion; Hackathon; Contagion; Software Applications; Software Development; Software Engineering; Technology Strategy; Technology Adoption; Technological Innovation; Information Infrastructure; Innovation Strategy; Digital Platforms; Network Effects; Applications and Software; Information Technology; Computer Industry; Computer Industry; Computer Industry; Computer Industry
Fang, Tommy Pan, Andy Wu, and David R. Clough. "Platform Diffusion at Temporary Gatherings: Social Coordination and Ecosystem Emergence." Art. 1. Strategic Management Journal 42, no. 2 (February 2021): 233–272. (Lead article.)
- November 2020 (Revised July 2022)
- Case
Dell Technologies: Bringing the Cloud to the Ground
By: Navid Mojir and V. Kasturi Rangan
The case tells the story of Dell Technologies and its efforts to revitalize its value proposition and escape a commodity trap by acquiring EMC for $67 billion—the largest tech acquisition in history. It also shows the deeply intertwined connections between a company’s... View Details
Keywords: Value Proposition; Go-to-market; Strategic Positioning; Mergers and Acquisitions; Business Strategy; Marketing Strategy; Technological Innovation; Business Divisions; Computer Industry; Computer Industry
Mojir, Navid, and V. Kasturi Rangan. "Dell Technologies: Bringing the Cloud to the Ground." Harvard Business School Case 521-036, November 2020. (Revised July 2022.)
- Article
Detecting Adversarial Attacks via Subset Scanning of Autoencoder Activations and Reconstruction Error
By: Celia Cintas, Skyler Speakman, Victor Akinwande, William Ogallo, Komminist Weldemariam, Srihari Sridharan and Edward McFowland III
Reliably detecting attacks in a given set of inputs is of high practical relevance because of the vulnerability of neural networks to adversarial examples. These altered inputs create a security risk in applications with real-world consequences, such as self-driving... View Details
Keywords: Autoencoder Networks; Pattern Detection; Subset Scanning; Computer Vision; Statistical Methods And Machine Learning; Machine Learning; Deep Learning; Data Mining; Big Data; Large-scale Systems; Mathematical Methods; Analytics and Data Science
Cintas, Celia, Skyler Speakman, Victor Akinwande, William Ogallo, Komminist Weldemariam, Srihari Sridharan, and Edward McFowland III. "Detecting Adversarial Attacks via Subset Scanning of Autoencoder Activations and Reconstruction Error." Proceedings of the International Joint Conference on Artificial Intelligence 29th (2020).
- 2019
- Working Paper
From Know-It-Alls to Learn-It-Alls: Executive Development in the Era of Self-Refining Algorithms, Collaborative Filtering and Wearable Computing
By: Mihnea Moldoveanu and Das Narayandas
We examine the future of executive education on a technological and cultural landscape that is imminent but different to the one we are accustomed to. We show how the contextualization, socialization and personalization of learning—avowed but distal goals of current... View Details
Keywords: Executive Education; Leadership Development; Technological Innovation; Customization and Personalization; Management Skills; Knowledge Acquisition; Knowledge Sharing
Moldoveanu, Mihnea, and Das Narayandas. "From Know-It-Alls to Learn-It-Alls: Executive Development in the Era of Self-Refining Algorithms, Collaborative Filtering and Wearable Computing." Harvard Business School Working Paper, No. 20-061, November 2019.
- August 2019
- Case
Huawei and the U.S.-China Trade War
By: Elie Ofek and John Masko
In 2019, Chinese smartphone maker and telecommunications empire Huawei was preparing to launch its new flagship smartphone series, the Mate 30. After years of explosive growth, the previous 18 months had been a challenge for the company. In early 2018, Huawei’s planned... View Details
Keywords: Trade; Global Strategy; International Relations; National Security; Mobile and Wireless Technology; Information Infrastructure; Volatility; Adaptation; Telecommunications Industry; China; United States; European Union
Ofek, Elie, and John Masko. "Huawei and the U.S.-China Trade War." Harvard Business School Case 520-017, August 2019.
- February 2018 (Revised December 2019)
- Case
Rise of the Drones: Identified Technologies
By: Andy Wu and George Gonzalez
The founder and CEO of Identified Technologies, a Pittsburgh-based drone software and services company, faces a dilemma when San Francisco–based DroneDeploy begins to disrupt the industry with its drone software platform. Identified Technologies needs to consider... View Details
Keywords: Applications and Software; Digital Platforms; Disruption; Network Effects; Computer Industry; Computer Industry; Pittsburgh; San Francisco
Wu, Andy, and George Gonzalez. "Rise of the Drones: Identified Technologies." Harvard Business School Case 718-482, February 2018. (Revised December 2019.)
- March 2017 (Revised February 2018)
- Case
VMware and the Public Cloud
By: Raffaella Sadun and Christine Snively
In 2015, VMware, a pioneer in server and network virtualization and a member of parent company EMC’s “federation” of companies, had set its sights on becoming a leading public cloud provider. Two years prior, VMware first entered the public cloud market with its vCloud... View Details
Keywords: Information Technology; Information Infrastructure; Applications and Software; Growth and Development Strategy; Internet and the Web; Computer Industry; Computer Industry; Computer Industry
Sadun, Raffaella, and Christine Snively. "VMware and the Public Cloud." Harvard Business School Case 717-480, March 2017. (Revised February 2018.)
- Article
Big Other: Surveillance Capitalism and the Prospects of an Information Civilization
By: Shoshana Zuboff
This article describes an emergent logic of accumulation in the networked sphere, 'surveillance capitalism,' and considers its implications for 'information civilization.' The institutionalizing practices and operational assumptions of Google Inc. are the... View Details
Keywords: Surveillance Capitalism; Big Data; Google; Information Society; Privacy; Internet Of Everything; Rights; Economic Systems; Analytics and Data Science; Internet and the Web; Ethics
Zuboff, Shoshana. "Big Other: Surveillance Capitalism and the Prospects of an Information Civilization." Journal of Information Technology 30, no. 1 (March 2015): 75–89.
- 2015
- Article
Scalable Detection of Anomalous Patterns With Connectivity Constraints
By: Skyler Speakman, Edward McFowland III and Daniel B. Neill
We present GraphScan, a novel method for detecting arbitrarily shaped connected clusters in graph or network data. Given a graph structure, data observed at each node, and a score function defining the anomalousness of a set of nodes, GraphScan can efficiently and... View Details
Speakman, Skyler, Edward McFowland III, and Daniel B. Neill. "Scalable Detection of Anomalous Patterns With Connectivity Constraints." Journal of Computational and Graphical Statistics 24, no. 4 (2015): 1014–1033.
- Article
Applying KISS to Healthcare Information Technology
By: Regina E. Herzlinger, Margo Seltzer and Mark Gaynor
Current public and private healthcare information technology initiatives have failed to achieve secure integration among providers. Applying the "keep it simple, stupid" principle offers the key guidance for solving this problem. View Details
Keywords: Technology; Health Care; Public Health; Information Technology Industry; Computer Networks; Computer Services Industries; Software; Hardware; Medical Services; Health Care and Treatment; Information Technology; Applications and Software; Information Infrastructure; Standards; Health Industry; Technology Industry; United States
Herzlinger, Regina E., Margo Seltzer, and Mark Gaynor. "Applying KISS to Healthcare Information Technology." Computer 46, no. 11 (November 2013): 72–74.
- September 2013 (Revised August 2015)
- Background Note
Leadership and Teaming
By: Ethan Bernstein
Small differences in the leadership of teams can have large consequences for the success of their efforts. Many initiatives fail not because of a fatal error in judgment or insufficient ideas, knowledge, motivation, or capabilities to deliver a solution. They fail... View Details
Keywords: Teams; Teaming; Leadership And Managing People; Leadership; Team Effectiveness; Team Performance; Team Design; Team Leadership; Teamwork; Team Process; Team Function; Team Launch; 60/30/10 Rule; Team Boundary; Distribution Of Leadership Authority; Self-Managed Teams; Virtual Teams; Unbounded Teams; Acts Of Leadership; Execution Teams; Decision Making Teams; Creativity Teams; Team Size; Task Design; Team Timeline; Team Roles; Team Representation; Diversity; Team Familiarity; Collective Intelligence; Team Stages Of Development; Team Coaching; Performance Pressure; X-Teams; Team Focus; Interaction; Management Teams; Managerial Roles; Management Systems; Management Style; Management Skills; Management Practices and Processes; Organizational Design; Organizational Structure; Performance Effectiveness; Performance Efficiency; Performance Productivity; Groups and Teams; Networks; Social Psychology; Behavior; Conflict and Resolution; Creativity; Social and Collaborative Networks; Satisfaction; Prejudice and Bias; Power and Influence; Personal Characteristics; Familiarity; Cognition and Thinking; Attitudes; Projects; Organizational Culture; Organizational Change and Adaptation; Leadership Development; Leadership Style; Leading Change; Knowledge Use and Leverage; Knowledge Sharing; Collaborative Innovation and Invention; Innovation and Management; Innovation Leadership; Design; Interpersonal Communication; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Computer Industry; Asia; North and Central America; South America; Atlantic Ocean; Central Asia; Europe; Latin America; Middle East; Oceania; West Indies
Bernstein, Ethan. "Leadership and Teaming." Harvard Business School Background Note 414-033, September 2013. (Revised August 2015.)
- November–December 2012
- Article
Toward a Theory of Extended Contact: The Incentives and Opportunities for Bridging Across Network Communities
By: Maxim Sytch, Adam Tatarynowicz and Ranjay Gulati
This study investigates the determinants of bridging ties within networks of interconnected firms. Bridging ties are defined as nonredundant connections between firms located in different network communities. We highlight how firms can enter into these relationships... View Details
Sytch, Maxim, Adam Tatarynowicz, and Ranjay Gulati. "Toward a Theory of Extended Contact: The Incentives and Opportunities for Bridging Across Network Communities." Organization Science 23, no. 6 (November–December 2012): 1658–1681.
- November 2012 (Revised May 2013)
- Case
ASUSTeK and the Google Nexus 7 Tablet
By: Willy C. Shih and Jyun-Cheng Wang
Days after Jerry Shen introduced a new tablet computer at the Consumer Electronics Show, a Google meeting convinced him to go with a lower price point and co-branding as the Nexus 7. While his company would have a premier position at launch, companies like Samsung... View Details
Keywords: Nexus; Google; ASUSTeK; Android; Tablet; Kindle; Kindle Fire; Notebook Computers; ODM; Apple; Price Point; App Store; Ecosystem; Open Handset Alliance; Reference Design; iPad; EMS; Electronic Manufacturing Services; Smartphone; Innovation and Management; Innovation Strategy; Technological Innovation; Product Marketing; Product Launch; Product Positioning; Industry Structures; Product Design; Product Development; Business Strategy; Competitive Strategy; Mobile and Wireless Technology; Digital Platforms; Information Technology; Internet and the Web; Computer Industry; Computer Industry; Computer Industry; Taiwan; United States
Shih, Willy C., and Jyun-Cheng Wang. "ASUSTeK and the Google Nexus 7 Tablet." Harvard Business School Case 613-056, November 2012. (Revised May 2013.)
- March–April 2012
- Article
The Rise and Fall of Small Worlds: Exploring the Dynamics of Social Structure
By: Ranjay Gulati, Maxim Sytch and Adam Tatarynowicz
This paper explores the interplay between social structure and economic action by examining some of the evolutionary dynamics of an emergent network that coalesces into a small-world system. The study highlights the small-world system's evolutionary dynamics at both... View Details
Keywords: Culture; System; Relationships; Globalization; Industry Clusters; Information; Networks; Competitive Strategy; Computer Industry
Gulati, Ranjay, Maxim Sytch, and Adam Tatarynowicz. "The Rise and Fall of Small Worlds: Exploring the Dynamics of Social Structure." Organization Science 23, no. 2 (March–April 2012): 449–471.
- May 2011 (Revised May 2011)
- Case
Nokia: The Burning Platform
By: Juan Alcacer, Tarun Khanna and Mary Furey
Overview on the state of Nokia since the “Emerging Nokia?” case was written. View Details
Keywords: Business Strategy; Corporate Strategy; Competitive Advantage; Marketing Strategy; Emerging Markets; Network Effects; Computer Industry; Computer Industry
Alcacer, Juan, Tarun Khanna, and Mary Furey. "Nokia: The Burning Platform." Harvard Business School Case 711-514, May 2011. (Revised May 2011.)