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      • December 2022
      • Technical Note

      Risks and Opportunities from the Transition to a Low Carbon Economy: A Business Analysis Framework

      By: George Serafeim
      The transition to a low carbon economy introduces many risks and opportunities for businesses. Risks emerge from regulatory actions, such as carbon taxes and cap and trade systems, technological innovation that develop alternatives for customers making existing... View Details
      Keywords: Risk Assessment; Opportunities; Environmental Sustainability; Carbon Footprint; Risk Management; Competitive Dynamics; Business Analysis; Climate Change; Accounting; Finance; Valuation; Business and Shareholder Relations; Technological Innovation; Transition; Product Positioning; Renewable Energy; Analysis
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      Serafeim, George. "Risks and Opportunities from the Transition to a Low Carbon Economy: A Business Analysis Framework." Harvard Business School Technical Note 123-014, December 2022.
      • December 2022 (Revised January 2023)
      • Case

      Cann: High Hopes for Cannabis Infused Beverages

      By: Ayelet Israeli and Anne V. Wilson
      Founded in 2018 by Jake Bullock and Luke Anderson, Cann sold “social tonics,” or cannabis-infused beverages. By 2022, the company had several notable celebrity investors and talent partners, had sold over 10 million beverages to consumers, was distributing in six... View Details
      Keywords: Stigma; Product Innovation; Product Introduction; Product Differentiation; New Products; New Product Marketing; New Product Management; Brand Management; Branding; Packaging; Positioning; Growth Strategy And Execution; Growth; Cannabis Industry; Purpose; Purpose Brands; LGBTQ; Direct-to-consumer; DTC; Regulations; Channels Of Distribution; Product Development; Product Marketing; Product Positioning; Product; Innovation and Invention; Brands and Branding; Marketing; Marketing Communications; Marketing Channels; Advertising; Advertising Campaigns; Digital Marketing; Market Entry and Exit; Governing Rules, Regulations, and Reforms; Consumer Products Industry; Consumer Products Industry; United States; Canada; North America
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      Israeli, Ayelet, and Anne V. Wilson. "Cann: High Hopes for Cannabis Infused Beverages." Harvard Business School Case 523-074, December 2022. (Revised January 2023.)
      • December 2022
      • Article

      I Don't 'Recall': The Decision to Delay Innovation Launch to Avoid Costly Product Failure

      By: Byungyeon Kim, Oded Koenigsberg and Elie Ofek
      Innovations embody novel features or cutting-edge components aimed at delivering desired customer benefits. Oftentimes, however, we observe the need to recall new products shortly after their introduction. Indeed, a firm may rush an innovation to market in an attempt... View Details
      Keywords: Innovation Management; Innovation And Strategy; Product Development Strategy; Product Introduction; Quality Control; Product Recalls; Game Theory; Market Timing; Innovation Strategy; Product Launch; Product Development
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      Kim, Byungyeon, Oded Koenigsberg, and Elie Ofek. "I Don't 'Recall': The Decision to Delay Innovation Launch to Avoid Costly Product Failure." Management Science 68, no. 12 (December 2022): 8889–8908.
      • Article

      Innovations in Retail Operations: Thirty Years of Lessons from Production and Operations Management

      By: Marshall Fisher and Ananth Raman
      We review papers published in Production and Operations Management (POM) during its thirty-year history that deal with retail operations issues with an empirical approach. The papers span a range of issues, from traditional ones like forecasting and inventory... View Details
      Keywords: RFID; Innovation and Invention; Technology Adoption; Operations; E-commerce; Strategy; Retail Industry
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      Fisher, Marshall, and Ananth Raman. "Innovations in Retail Operations: Thirty Years of Lessons from Production and Operations Management." Special Issue on The 30th Anniversary Issue of Production and Operations Management edited by Subodha Kumar and Christopher S. Tang. Production and Operations Management 31, no. 12 (December 1, 2022): 4452–4461.
      • 2022
      • Working Paper

      Regulatory Incentives for Innovation: The FDA's Breakthrough Therapy Designation

      By: Amitabh Chandra, Jennifer Kao, Kathleen Miller and Ariel D. Stern
      Regulators of new products confront a tradeoff between speeding a new product to market and collecting additional product quality information. The FDA’s Breakthrough Therapy Designation (BTD) provides an opportunity to understand if a regulator can use new policy to... View Details
      Keywords: Research and Development; Governing Rules, Regulations, and Reforms; Product Development
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      Chandra, Amitabh, Jennifer Kao, Kathleen Miller, and Ariel D. Stern. "Regulatory Incentives for Innovation: The FDA's Breakthrough Therapy Designation." NBER Working Paper Series, No. 30712, December 2022.
      • 2021
      • Working Paper

      The Contribution of High-Skilled Immigrants to Innovation in the United States

      By: Shai Bernstein, Rebecca Diamond, Abhisit Jiranaphawiboon, Timothy McQuade and Beatriz Pousada
      We characterize the contribution of immigrants to US innovation, both through their direct productivity as well as through their indirect spillover effects on their native collaborators. To do so, we link patent records to a database containing the first five digits of... View Details
      Keywords: Innovation; Economic Growth; Immigrants; Innovation and Invention; Collaborative Innovation and Invention; Patents; Innovation Strategy
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      Bernstein, Shai, Rebecca Diamond, Abhisit Jiranaphawiboon, Timothy McQuade, and Beatriz Pousada. "The Contribution of High-Skilled Immigrants to Innovation in the United States." Harvard Business School Working Paper, No. 22-065, December 2021. (NBER Working Paper Series, No. 30797, December 2022.)
      • November 2022 (Revised March 2023)
      • Supplement

      JUUL and the Vaping Revolution: A 2022 Update

      By: Michael W. Toffel and Sarah Mehta
      This slide deck provides a brief update (2019-2022) on the rise and fall of JUUL Labs, the maker of the popular JUUL e-cigarette. View Details
      Keywords: Electronic Cigarettes; E-Cigarettes; Vaping; Nicotine Replacement; JUUL; Juuling; Government Regulation; Advertising; Advertising Campaigns; Digital Marketing; Customers; Innovation and Invention; Innovation Strategy; Marketing; Ethics; Brands and Branding; Marketing Communications; Marketing Strategy; Product Marketing; Corporate Social Responsibility and Impact; Social Issues; Technology Industry; California
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      Toffel, Michael W., and Sarah Mehta. "JUUL and the Vaping Revolution: A 2022 Update." Harvard Business School PowerPoint Supplement 623-012, November 2022. (Revised March 2023.)
      • November 2022 (Revised March 2023)
      • Supplement

      JUUL and the Vaping Revolution: A 2022 Update

      By: Michael W. Toffel and Sarah Mehta
      This case provides a brief update (2019-2022) on the rise and fall of JUUL Labs, the maker of the popular JUUL e-cigarette. View Details
      Keywords: Electronic Cigarettes; E-Cigarettes; Vaping; Nicotine Replacement; JUUL; Juuling; Government Regulation; Advertising; Advertising Campaigns; Digital Marketing; Customers; Innovation and Invention; Innovation Strategy; Marketing; Ethics; Brands and Branding; Marketing Communications; Marketing Strategy; Product Marketing; Corporate Social Responsibility and Impact; Social Issues; Technology Industry; California
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      Toffel, Michael W., and Sarah Mehta. "JUUL and the Vaping Revolution: A 2022 Update." Harvard Business School Supplement 623-011, November 2022. (Revised March 2023.)
      • November 2022
      • Case

      Ajax Health: A New Model for Medical Technology Innovation

      By: Regina E. Herzlinger and Ben Creo
      This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets... View Details
      Keywords: Business Startups; Success; Innovation Strategy; Mergers and Acquisitions; Market Entry and Exit; Financial Strategy; Business Model; Partners and Partnerships; Entrepreneurship; Private Equity; Technology Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
      • November 2022 (Revised June 2023)
      • Case

      UGG Steps into the Metaverse

      By: Shunyuan Zhang, Sharon Joseph, Sunil Gupta and Julia Kelley
      In the fall of 2022, boot maker UGG and its parent company, Deckers, were working to position the brand in the nascent but fast growing metaverse. The metaverse, the online realm that individual users could navigate as digital avatars, was becoming more commercialized,... View Details
      Keywords: Metaverse; Digital Marketing; Innovation and Invention; Marketing Channels; Marketing Strategy; Social Marketing; Internet and the Web; Apparel and Accessories Industry; Fashion Industry; Information Technology Industry; United States
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      Zhang, Shunyuan, Sharon Joseph, Sunil Gupta, and Julia Kelley. "UGG Steps into the Metaverse." Harvard Business School Case 523-013, November 2022. (Revised June 2023.)
      • October 25, 2022
      • Article

      Why Sharing Economic Growth with the Community Is Good Business

      By: José A. Tiburcio, Lino Miguel Dias and Robert S. Kaplan
      Subsistence dairy ranchers in Central America struggle to stay afloat during the dry season when grass is scarce. Global life sciences company Bayer has launched a program to enable them to produce their own corn silage feed. The results of this program are helping to... View Details
      Keywords: Sharing Economy; Innovation; Economic Growth; Poverty; Production; Supply Chain; Social Enterprise; Agriculture and Agribusiness Industry; Central America
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      Tiburcio, José A., Lino Miguel Dias, and Robert S. Kaplan. "Why Sharing Economic Growth with the Community Is Good Business." Harvard Business Review (website) (October 25, 2022).
      • October 2022
      • Case

      Single.Earth

      By: Rembrand Koning and Emer Moloney
      Estonian greentech company Single.Earth is launching a nature-backed token that is linked to and funds the protection of a specific plot fo land. The first landowners had been onboarded to the company's Digital Twin, a virtual representation of the planet's natural... View Details
      Keywords: Alternative Assets; Business Startups; Entrepreneurship; Climate Change; Environmental Sustainability; Green Technology; Natural Resources; Pollution; Analytics and Data Science; Marketing; Product Marketing; Product Launch; Product Positioning; Markets; Market Timing; Strategy; Green Technology Industry; Estonia
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      Koning, Rembrand, and Emer Moloney. "Single.Earth." Harvard Business School Case 723-388, October 2022.
      • October 2022 (Revised December 2022)
      • Case

      Reimagining Enel: Enabling Sustainable Progress (A)

      By: Michael L. Tushman and Kerry Herman
      CEO Francesco Starace is considering what is next for Enel SpA, one of world's largest energy companies. From 2014 to 2022, he has wrought a dramatic transformation at Enel, restructuring the company's business units; redeploying senior talent across functions and... View Details
      Keywords: Leadership; Leadership And Change Management; Leadership Style; Leadership Succession; Renewables; Energy; Transformation; Renewable Energy; Business Divisions; Digital Transformation; Restructuring; Organizational Structure; Energy Industry; Europe; Latin America; North America; Spain; Italy
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      Tushman, Michael L., and Kerry Herman. "Reimagining Enel: Enabling Sustainable Progress (A)." Harvard Business School Case 423-001, October 2022. (Revised December 2022.)
      • October 2022 (Revised July 2025)
      • Case

      Driving Decarbonization at BMW

      By: Shirley Lu, George Serafeim and Michael W. Toffel
      The case describes BMW’s electrification and decarbonization strategy, and how the company measured carbon emissions throughout the life cycle of its vehicles and used tools like carbon abatement cost curves to evaluate decarbonization opportunities. In mid-2022,... View Details
      Keywords: Decarbonization; Climate Change; Environment; Sustainability; Carbon Accounting; Carbon; Carbon Abatement; Electric Vehicles; Automobiles; Transportation; Environmental Accounting; Environmental Management; Environmental Sustainability; Accounting; Strategy; Technological Innovation; Supply Chain; Business and Stakeholder Relations; Transportation Industry; Auto Industry; Battery Industry; Germany; China; United States; Europe
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      Lu, Shirley, George Serafeim, and Michael W. Toffel. "Driving Decarbonization at BMW." Harvard Business School Case 123-008, October 2022. (Revised July 2025.)
      • October 2022 (Revised September 2024)
      • Case

      Podimetrics: Next Steps for Diabetes Cases

      By: Regina E. Herzlinger and Ben Creo
      Podimetrics, a virtual care management company treating adults with acute diabetes, sat at the intersection of medical device technology, digital health, and health services. Its SmartMat had demonstrated that it could help prevent amputations and that people with... View Details
      Keywords: Health Care; Health Care Delivery; Health Care Entrepreneurship; Health Care Outcomes; Diabetes; Chronic Disease; Chronic Illness; Health Care and Treatment; Health Disorders; Medical Specialties; Technological Innovation; Innovation Strategy; Product Development; Business Model; Customer Focus and Relationships; Medical Devices and Supplies Industry; Health Industry
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      Herzlinger, Regina E., and Ben Creo. "Podimetrics: Next Steps for Diabetes Cases." Harvard Business School Case 323-015, October 2022. (Revised September 2024.)
      • October 2022
      • Article

      How Leaders with Divergent Visions Generate Novel Strategy: Navigating the Paradox of Preservation and Modernization in Swiss Watchmaking

      By: Ryan Raffaelli, Rich DeJordy and Rory M. McDonald
      How do leaders with divergent visions for their organization come together to create a novel strategy? This paper employs paradox as a lens to investigate how leader-dyads can integrate opposing strategies to produce a new, generative approach. Drawing on a qualitative... View Details
      Keywords: Strategic Paradoxes; Senior Leaders; Organizational Reinvention; Leadership; Technological Innovation; Innovation and Management; Innovation Strategy; Change; Consumer Products Industry; Consumer Products Industry; Switzerland
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      Raffaelli, Ryan, Rich DeJordy, and Rory M. McDonald. "How Leaders with Divergent Visions Generate Novel Strategy: Navigating the Paradox of Preservation and Modernization in Swiss Watchmaking." Academy of Management Journal 65, no. 5 (October 2022): 1593–1622.
      • September 2022 (Revised November 2023)
      • Case

      Wordle

      By: Karen G. Mills, Christina Wallace, Ebehi Iyoha, Gabriella Elanbeck and Morgane Herculano
      After sourdough bread, countertop chive gardens, and vaccine selfies came a pandemic-era trend that everyone seemed to be in on: one daily chance to guess a five-letter word and crow about your success on social media via little green and yellow squares. From a... View Details
      Keywords: Games; Innovation; General Management; Mergers and Acquisitions; Trends; Entrepreneurship; Bids and Bidding; Consumer Behavior; Entertainment and Recreation Industry; Technology Industry
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      Mills, Karen G., Christina Wallace, Ebehi Iyoha, Gabriella Elanbeck, and Morgane Herculano. "Wordle." Harvard Business School Case 323-032, September 2022. (Revised November 2023.)
      • September 2022
      • Article

      Find and Replace: R&D Investment Following the Erosion of Existing Products

      By: Joshua L. Krieger, Xuelin Li and Richard T. Thakor
      How do innovative firms react when existing products experience negative shocks? We explore this question with detailed project-level data from drug development firms. Using FDA Public Health Advisories as idiosyncratic negative shocks to approved drugs, we first... View Details
      Keywords: R&D Investments; Drug Development; Product Shocks; M&A; Biopharmaceutical Industry; FDA; System Shocks; Research and Development; Investment; Decision Making; Pharmaceutical Industry
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      Krieger, Joshua L., Xuelin Li, and Richard T. Thakor. "Find and Replace: R&D Investment Following the Erosion of Existing Products." Management Science 68, no. 9 (September 2022): 6552–6571.
      • July 2022 (Revised February 2024)
      • Teaching Note

      The DivaCup: Navigating Distribution and Growth

      By: Ayelet Israeli
      Teaching Note for HBS Case No. 519-055. When the mother-daughter founders of DivaCup set out with a mission to disrupt the menstrual care industry with an innovative product form, they initially struggled to gain legitimacy and convince retailers to carry their unique... View Details
      Keywords: Female; Female Ceo; Female Entrepreneur; Female Protagonist; Health & Wellness; Healthcare; Price Policies; Minimum Advertised Price; Differentiation; Positioning; Growth; Health; Health Care and Treatment; Price; Disruption; Distribution; Distribution Channels; Competitive Strategy; Competition; Growth Management; Mission and Purpose; Product Development; Product Marketing; Product Launch; Product Positioning; Advertising; Business Startups; Internet and the Web; Entrepreneurship; Social Entrepreneurship; Social Issues; Social Enterprise; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Consumer Products Industry; Canada; United States; United Kingdom
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      Israeli, Ayelet. "The DivaCup: Navigating Distribution and Growth." Harvard Business School Teaching Note 523-008, July 2022. (Revised February 2024.)
      • Article

      Online Experimentation: Benefits, Operational and Methodological Challenges, and Scaling Guide

      By: Iavor Bojinov and Somit Gupta
      In the past decade, online controlled experimentation, or A/B testing, at scale has proved to be a significant driver of business innovation. The practice was first pioneered by the technology sector and, more recently, has been adopted by traditional companies... View Details
      Keywords: A/B Testing; Experimentation; Data-driven Culture; Product Development; Innovation and Invention; Digital Transformation
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      Bojinov, Iavor, and Somit Gupta. "Online Experimentation: Benefits, Operational and Methodological Challenges, and Scaling Guide." Harvard Data Science Review, no. 4.3 (Summer, 2022).
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