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  • 2008
  • Chapter

Where is the Pharmacy to the World? Pharmaceutical Industry Location and International Regulatory Variation

By: Arthur A. Daemmrich
A consumer-oriented model for drug development and use has attracted attention in recent years as an alternative to the much-maligned approach of mass-marketing blockbuster drugs. In a parallel development, patients and disease-based organizations have assumed greater... View Details
Keywords: Geographic Location; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Demand and Consumers; Pharmaceutical Industry; European Union; Germany; United States
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  • 2022
  • Book

Healthy Buildings: How Indoor Spaces Can Make You Sick—or Keep You Well

By: Joseph G. Allen and John D. Macomber
For too long we’ve designed buildings that haven’t focused on the people inside—their health, their ability to work effectively, and what that means for the bottom line. An authoritative introduction to a movement whose vital importance is now all too clear, Healthy... View Details
Keywords: COVID-19; Buildings and Facilities; Health; Health Pandemics; Safety
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  • January 2018 (Revised January 2019)
  • Case

ZappRx

By: Jeffrey J. Bussgang and Olivia Hull
In October 2015, ZappRx founder Zoe Barry is deciding between two business models for her health technology start-up. Her product, a software application that aims to expedite the prescription fulfillment process for patients with rare diseases, has attracted interest... View Details
Keywords: Speciality Drugs; Hub Services; Pivot; Speciality Prescriptions; Health Care and Treatment; Customization and Personalization; Internet and the Web; Business Model; Decision Choices and Conditions; Pharmaceutical Industry; Massachusetts
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  • 09 May 2017
  • First Look

New Research and Ideas, May 9

consider evolving into a chronic disease management company? Purchase this case:https://cb.hbsp.harvard.edu/cbmp/product/317007-PDF-ENG Harvard Business School Case 317-094 Sesame Workshop: Bringing Big Bird Back to Health (Abridged)... View Details
Keywords: Sean Silverthorne
  • March 2023 (Revised June 2025)
  • Case

Close Concerns: Diabetes Research and Advocacy

By: Regina E. Herzlinger and Brian L. Walker
Diagnosed with diabetes at the age of 18, Kelly Close understood the importance of balancing consistency and iteration. This principle had also informed her professional work, which started with a rapid promotion from financial analyst at Goldman Sachs to an analyst... View Details
Keywords: Diabetes; Health; Health Care; Health Care And Treatment; Health Care Outcomes; Health Care Industry; Knowledge Dissemination; Outcome or Result; Equality and Inequality; Business Model; Entrepreneurship
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  • 03 Apr 2009
  • Working Paper Summaries

Applying the Care Delivery Value Chain: HIV/AIDS Care in Resource Poor Settings

Keywords: by Joseph Rhatigan, Sachin Jain, Joia S. Mukherjee & Michael E. Porter; Health
  • October 2012 (Revised October 2013)
  • Case

Rock Health

By: Robert F. Higgins and Ian McKown Cornell
Rock Health was a San Francisco–based nonprofit organization offering accelerator services to spur innovation at the intersection of healthcare and technology. The company was the creation of Halle Tecco (HBS '11) and her HBS classmate Nate Gross (HBS '11), who met... View Details
Keywords: Innovation; Incubation; Healthcare Technology; Startups; Entrepreneurship; Innovation and Management; Health Care and Treatment; Business Startups; Health Industry; San Francisco; California; United States
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  • February 2022 (Revised November 2022)
  • Case

Nuritas

By: Mitchell Weiss, Satish Tadikonda, Vincent Dessain and Emer Moloney
Nora Khaldi had built a technology “to unlock the power of nature” in the service of extending human lifespan and improving health, and now in April 2020 was debating telling her Board of Directors she wanted to put on ice some of her discoveries. Nuritas, the company... View Details
Keywords: Cash Burn; Cash Flow Analysis; Pharmaceutical Companies; Founder; Artificial Intelligence; AI; Entrepreneurship; Health Testing and Trials; Health Care and Treatment; Decision Making; Market Entry and Exit; AI and Machine Learning; Pharmaceutical Industry
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  • January 2009 (Revised February 2009)
  • Case

Sydney IVF: Stem Cell Research

By: Robert L. Simons, Kathryn Rosenberg and Natalie Kindred
This case examines the strategy implementation and risk management decisions at Sydney IVF, a research-based in vitro fertilization and stem cell company based in Australia. Drs. Robert Jansen and Jock Anderson, who co-founded Sydney IVF in 1986, developed novel... View Details
Keywords: Ethics; Governing Rules, Regulations, and Reforms; Innovation and Management; Growth and Development Strategy; Risk Management; Genetics; Commercialization; Health Industry; Australia
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  • 2023
  • Article

Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset

By: Junling Liu, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu and Michael Lingzhi Li
Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address this gap, we introduce CMExam,... View Details
Keywords: Large Language Model; AI and Machine Learning; Analytics and Data Science; Health Industry
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  • August 2016 (Revised August 2016)
  • Teaching Note

Intrapreneurship at DaVita Healthcare Partners

By: Joseph B. Fuller and Matthew Preble
DaVita Healthcare Partners Inc. (DaVita) is one of the U.S.'s leading dialysis providers, a process whereby persons with end-stage renal disease (ESRD) are connected to a machine that performs the functions of a healthy kidney. Kent Thiry, DaVita's CEO, has expanded... View Details
Keywords: Intrapreneurship; Entrepreneurial Organizations; Startup Management; Startup; Strategic Positioning; Corporate Entrepreneurship; Corporate Strategy; Business Startups; Strategic Planning; Competitive Strategy; Health Industry; United States
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  • May 2023 (Revised June 2023)
  • Supplement

Novartis (C): Reimagining Medicine

By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
Keywords: Health Testing and Trials; Health Care and Treatment; Business Model; Problems and Challenges; Pharmaceutical Industry; Switzerland
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  • April 2006
  • Case

Adrian Ivinson at the Harvard Center for Neurodegeneration and Repair

By: Robert Steven Kaplan and Ayesha Kanji
Adrian Ivinson is the director of Harvard Center for Neurodegeneration and Repair (HCNR), a not-for-profit research center at the Harvard Medical School (HMS). The center was started in late 2000 with a gift of $37.5 million from an anonymous donor. Its mandate was to... View Details
Keywords: Leadership Style; Power and Influence; Organizational Culture; Research and Development; Nonprofit Organizations; Motivation and Incentives; Change Management; Alignment; Collaborative Innovation and Invention; Health Industry; Massachusetts
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  • April 2024 (Revised December 2024)
  • Case

Anthropic: Building Safe AI

By: Shikhar Ghosh and Shweta Bagai
In late 2024, Anthropic, a leading AI safety and research company, achieved a significant breakthrough with computer use capabilities that allowed AI to interact with computers like humans. Co-founded by former OpenAI employees and known for its generative AI... View Details
Keywords: AI and Machine Learning; Corporate Accountability; Corporate Social Responsibility and Impact; Business Growth and Maturation; Corporate Strategy; Technology Industry; United States
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  • September 2015
  • Article

Design and Implementation of a Privacy Preserving Electronic Health Record Linkage Tool in Chicago

By: Abel Kho, John Cashy, Kathryn Jackson, Adam Pah, Satyender Goel, Jorn Boehnke, John Eric Humphries, Scott Duke Kominers and et al.
Objective
To design and implement a tool that creates a secure, privacy preserving linkage of electronic health record (EHR) data across multiple sites in a large metropolitan area in the United States (Chicago, IL), for use in clinical... View Details
Keywords: Information; Customers; Safety; Rights; Ethics; Entrepreneurship; Health Care and Treatment; Health Industry; Chicago
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  • 10 Oct 2007
  • First Look

First Look: First Look: October 10

  Working PapersTesting Limits to Policy Reversal: Evidence from Indian Privatizations Authors:Siddhartha G. Dastidar, Raymond Fisman, and Tarun Khanna Abstract We examine the effect of regime change on privatization using the 2004 election surprise in India. The... View Details
Keywords: Martha Lagace
  • 2018
  • Chapter

The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century

By: Nicholas Bagley, Benjamin Berger, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
On the 35th anniversary of the adoption of the Orphan Drug Act (ODA), we describe the enormous changes in the markets for therapies for rare diseases that have emerged over recent decades. The most prominent example is the fact that the profit-maximizing price of new... View Details
Keywords: Health Care and Treatment; Laws and Statutes; Research and Development; Investment; Markets; Monopoly
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  • January 2017
  • Supplement

Intrapreneurship at DaVita HealthCare Partners: Cash Flow Tool

By: Joseph B. Fuller and Christopher Payton
DaVita Healthcare Partners Inc. (DaVita) is one of the U.S.'s leading dialysis providers, a process whereby persons with end-stage renal disease (ESRD) are connected to a machine that performs the functions of a healthy kidney. Kent Thiry, DaVita's CEO, has expanded... View Details
Keywords: Intrapreneurship; Entrepreneurial Organizations; Startup Management; Startup; Strategic Positioning; Corporate Entrepreneurship; Corporate Strategy; Business Startups; Strategic Planning; Competitive Strategy; Health Industry; United States
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  • 07 Feb 2012
  • First Look

First Look: February 7

efforts all around GE. But will this focus enable GE to achieve and maintain market leadership across a healthcare market that is being buffeted by strong currents, including cost pressures, changes in chronic disease patterns, and... View Details
Keywords: Sean Silverthorne
  • 2011
  • Article

Scalable Detection of Anomalous Patterns With Connectivity Constraints

By: Skyler Speakman, Edward McFowland III and Daniel B. Neill
We present GraphScan, a novel method for detecting arbitrarily shaped connected clusters in graph or network data. Given a graph structure, data observed at each node, and a score function defining the anomalousness of a set of nodes, GraphScan can efficiently and... View Details
Keywords: Biosurveillance; Event Detection; Graph Mining; Scan Statistics; Spatial Scan Statistic
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