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July 2025
Case

Insilico’s Rentosertib Dilemma: A Star in the Pipeline?

By: Michael Lingzhi Li, Brian Mao Fu and Billy Chan

In 2024, the AI biotech firm Insilico Medicine faced a pivotal decision about its new drug, Rentosertib. Discovered and designed using artificial intelligence to treat a lung disease, Rentosertib had successfully advanced to Phase II trials — a first in global... View Details

Keywords: Drug Development; Pharmaceuticals; Artificial Intelligence; Hong Kong; Boston; New York (city, NY)

June 2025
Case

Redefining the Edge: Jahez’s Strategic Pivot in Saudi Arabia’s Food Delivery Battle

By: Krishna G. Palepu and Ahmed Dahawy

Jahez made its mark in Saudi Arabia’s food delivery market by serving customers willing to pay more for reliable, high-quality service—a segment largely overlooked by other platforms. As the company grew, it expanded into the mass market and developed a network of... View Details

Keywords: Acquisition; Business Conglomerates; Corporate Entrepreneurship; Innovation Strategy; Digital Platforms; Logistics; Business Strategy; Competition; Competitive Strategy; Competitive Advantage; Expansion; Food and Beverage Industry; Saudi Arabia

May 2025 (Revised June 2025)
Supplement

Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (D)

By: Linda A. Hill and Lydia Begag

This fourth installment in the Pfizer Global Clinical Supply (GCS) transformation case series highlights how over a decade of cultural and digital evolution positioned GCS to meet unprecedented global challenges. In 2011, Michael Ku became the Vice President of GCS and... View Details

May 2025 (Revised June 2025)
Case

Daiichi Sankyo: Steering a Global Organization

By: Tiona Zuzul, Amy C. Edmondson and Cat Huang

In the spring of 2023, Sunao Manabe, CEO of Daiichi Sankyo, reflected on a pivotal decision. A large Western pharmaceutical company had made a bid to partner with Daiichi Sankyo to develop the next three products in its oncology pipeline. Daiichi Sankyo, a 125-year old... View Details

Keywords: Strategy; Culture Change; Decision-making; Leadership; Culture; Innovation; Psychological Safety

2025
Chapter

Marjorie Yang Mun Tak 楊梅德：Entrepreneur and Innovator

By: William C. Kirby

BOOK ABSTRACT:
Chinese Encounters with America tells the stories of twelve women and men whose American experiences transformed their lives and influenced China’s trajectory, with a particular focus on the period after Beijing and Washington established... View Details

Keywords: International Relations; Leadership; China

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April 2025
Case

Kleiner Perkins (2019)

By: Jo Tango and Srimayi Mylavarapu

Kleiner Perkins, founded in 1972, quickly rose to prominence as one of Silicon Valley’s leading venture capital firms, earning a reputation for early investments in industry giants like Google, Amazon, and Citrix. However, a bold, strategic pivot to cleantech investing... View Details

Keywords: Venture Capital; Investment Funds; Technological Innovation; Entrepreneurial Finance; Organizational Change and Adaptation; Financial Services Industry

April 2025 (Revised May 2025)
Case

Adobe: GenAI Opportunity or Threat?

By: Sunil Gupta, Rajiv Lal and Allison Ciechanover

In December 2022, Adobe CEO Shantanu Narayen faced a pivotal strategic decision due to the rapid rise of generative AI image models from OpenAI, Midjourney, and StabilityAI. Adobe, a leader in digital media and marketing software with a 40-year legacy of innovation and... View Details

Keywords: Customer Relationship Management; Ethics; AI and Machine Learning; Trust; Business Strategy; Technology Industry; San Jose

March 2025
Supplement

Wasabi Technologies (B)

By: Lou Shipley and Stacy Straaberg

Set in 2019, the “Wasabi Technologies (A)” case centers on Wasabi Technologies (Wasabi), a successful hot cloud storage company based in Boston, Massachusetts. Founder and CEO David Friend is ready to scale the four-year-old venture rapidly. Wasabi had so far focused... View Details

Keywords: Information Management; Sales; Product Development; Growth and Development Strategy; Business Strategy; Information Technology Industry; United States; Massachusetts; Boston

March 2025
Teaching Plan

Wasabi Technologies (A) and (B)

By: N. Louis Shipley and Stacy Straaberg

Teaching Plan for HBS Case Nos. 823-021 and 825-035. Set in 2019, the “Wasabi Technologies (A)” case centers on Wasabi Technologies (Wasabi), a successful hot cloud storage company based in Boston, Massachusetts. Founder and CEO David Friend is ready to scale the... View Details

Keywords: Sales; Product Development; Growth and Development Strategy; Business Divisions; Business Strategy; Marketing Strategy; Distribution Channels; Information Technology Industry; United States; Massachusetts; Boston

March 2025
Case

Metaphysic AI: Rethinking the Value of Human Expertise

By: Zoë B. Cullen, Shikhar Ghosh and Shweta Bagai

In early 2025, Thomas Graham, CEO of Metaphysic, a leading AI generative video company confronted fundamental questions about who should control digital identity in a world where AI could perfectly recreate human likeness. Founded in 2021, Metaphysic first rose to fame... View Details

Keywords: Business Model; Ethics; AI and Machine Learning; Intellectual Property; Rights; Negotiation; Value; Motion Pictures and Video Industry; Technology Industry

March 2025
Case

Harvey: AI for Lawyers

By: Suraj Srinivasan, Charles Krumholz and Radhika Kak

In early 2025, Winston Weinberg and Gabe Pereyra, co-founders of Harvey AI, reflected on the company’s meteoric rise as a pioneer in AI-powered legal technology. Since its founding in 2022, Harvey had transformed how lawyers approached research, drafting, and document... View Details

Keywords: Innovation Strategy; Business Startups; AI and Machine Learning; Technological Innovation; Growth and Development Strategy; Product Positioning; Legal Services Industry; Technology Industry; New York (city, NY); San Francisco; London

2025
Article

Educating Students and Professionals on the Business Implications of Climate Change

By: Michael W. Toffel

As climate change poses unprecedented challenges and opportunities, the private sector must play a pivotal role in both adaptation and mitigation efforts. This article discusses the new Harvard Business School Online course, Business and Climate Change, designed to... View Details

Keywords: Climate Impact; Online Courses; Online Education; Decarbonization; Mitigation Policies; Climate Risk; Climate Change; Risk Management; Science; Policy; Business Education; Adaptation

January 2025
Case

Arsenal Capital Partners' Refinancing of Pinnacle

By: Victoria Ivashina and Srimayi Mylavarapu

Arsenal Capital Partners’ portfolio company, Pinnacle, a leading producer of high-performance adhesive technologies, has experienced rapid growth under Arsenal’s ownership. Over just two years, Pinnacle's EBITDA increased from $13.5 million to $60 million. By mid-2021,... View Details

Keywords: Business Exit or Shutdown; Decision Choices and Conditions; Private Equity; Financing and Loans; Growth Management

January 2025 (Revised April 2025)
Case

Doing Business in Cairo: Navigating a Path to Economic Resilience

By: A. Zelleke and Ahmed Dahawy

Egypt has long been a pivotal force in the Middle East and North Africa. Located at a crossroads of global trade routes, the country was a strategic partner for numerous regional and global powers. However, a substantial currency devaluation in 2016 brought many... View Details

Keywords: Business; Developing Countries and Economies; Economic Slowdown and Stagnation; Inflation and Deflation; Macroeconomics; Cross-Cultural and Cross-Border Issues; Globalized Economies and Regions; International Relations; Emerging Markets; Risk and Uncertainty; Culture; Economy; Country; Currency; Investment; Governing Rules, Regulations, and Reforms; Egypt

January 2025
Case

Intuition Robotics: An AI Companion for Older Adults

By: Amit Goldenberg, Elie Ofek and Orna Dan

Intuition Robotics, a startup that makes an AI companion robot to alleviate older adults’ loneliness, debates whether to pursue a B2C model or B2G route. If it opts for the government vertical, it must determine how to negotiate a favorable deal. Two weeks after... View Details

Keywords: Business Model; Business Startups; AI and Machine Learning; Technology Adoption; Product Launch; Market Entry and Exit; Negotiation Offer; Business and Government Relations; Health Industry; Technology Industry; United States; New York (state, US)

January 2025 (Revised March 2025)
Case

Hunter Point Capital

By: Josh Lerner, John D. Dionne and Srimayi Mylavarapu

In the spring of 2023, Hunter Point Capital faced a pivotal decision that could define its trajectory as a new player in the growing GP stakes business. As the firm neared completion of three high-profile GP stakes investments, consuming nearly a third of its initial... View Details

Keywords: Investment Funds; Business Strategy; Diversification; Expansion; Growth and Development Strategy; Opportunities

January 2025
Supplement

Martin Luther King, Jr.: A Young Minister Confronts the Challenges of Montgomery (B)

By: Nien-hê Hsieh and Derek C. M. van Bever

Recounts a pivotal moment in Martin Luther King Jr.'s life during the Montgomery Bus Boycott, where a profound prayer amidst threats to his life renewed his faith and resolve to lead the movement. This transformative experience marked the beginning of his lifelong... View Details

Keywords: Spirituality; Civil Rights; Manging Uncertainty; Leadership; Decision Making; Values and Beliefs; Civil Society or Community; Social Issues; Power and Influence; Alabama

December 2024 (Revised July 2025)
Case

Arcor Group: Navigating Agribusiness Challenges in Argentina

By: Alberto Cavallo, Jenyfeer Martinez Buitrago and Mariana Cal

In 2016, Arcor Group, Argentina's leading food company, faced a pivotal decision regarding its newly formed Agribusiness division. CEO Luis Alejandro Pagani and Modesto Magadán, General Manager of the Agribusiness division, evaluated whether to increase investments in... View Details

Keywords: Factories, Labs, and Plants; Market Entry and Exit; Production; Business Strategy; Growth and Development Strategy; Food and Beverage Industry; Agriculture and Agribusiness Industry; Argentina

December 2024 (Revised March 2025)
Case

WayCool: Addressing Food Loss

By: Rajiv Lal and Kairavi Dey

Headquartered in Chennai, India, WayCool started by focusing on solving the growing challenge of food losses and low farmer incomes. Dasari and Jayaraman, surprised at the amount of fruits and vegetables lost in the agricultural supply chain, set up the company with... View Details

Keywords: Agribusiness; Entrepreneurship; Business Model; Food; Supply Chain; Loss; Expansion; Distribution Channels; Agriculture and Agribusiness Industry; Asia; India; Bangalore; Chennai

November 2024
Case

Demond Martin and WellWithAll

By: Hise Gibson, Archie L. Jones and Ai-Ling Jamila Malone

This case study chronicles the transformative entrepreneurial path of Demond Martin, co-founder and CEO of WellWithAll, a health and wellness startup. Motivated by a pivotal life experience and deep concern for racial health inequities, Martin transitions from a... View Details

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