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      • Faculty Publications  (342)

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      • March 2021
      • Case

      VideaHealth: Building the AI Factory

      By: Karim R. Lakhani and Amy Klopfenstein
      Florian Hillen, co-founder and CEO of VideaHealth, a startup that used artificial intelligence (AI) to detect dental conditions on x-rays, spent the early years of his company laying the groundwork for an AI factory. A process for quickly building and iterating on new... View Details
      Keywords: Artificial Intelligence; Innovation and Invention; Disruptive Innovation; Technological Innovation; Information Technology; Applications and Software; Technology Adoption; Digital Platforms; Entrepreneurship; AI and Machine Learning; Technology Industry; Medical Devices and Supplies Industry; North and Central America; United States; Massachusetts; Cambridge
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      Lakhani, Karim R., and Amy Klopfenstein. "VideaHealth: Building the AI Factory." Harvard Business School Case 621-021, March 2021.
      • February 2021
      • Case

      Threadless: The Renewal of an Online Community

      By: Shane Greenstein, Karim Lakhani and Christian Godwin
      Threadless, an online apparel company and artist community which Jake Nickell founded in 2000, continued to maintain its status as a top company in the online apparel industry during its second decade. From 2010 to 2020, Threadless continued to operate its... View Details
      Keywords: Business Model; Decision Making; Entrepreneurship; Innovation and Invention; Leading Change; Management; Marketing; Product Launch; Operations; Supply Chain; Distribution; Networks; Sales; Strategy; Adaptation; Information Technology; Applications and Software; Digital Platforms; Apparel and Accessories Industry; Technology Industry; North America
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      Greenstein, Shane, Karim Lakhani, and Christian Godwin. "Threadless: The Renewal of an Online Community." Harvard Business School Case 621-056, February 2021.
      • February 2021 (Revised June 2021)
      • Case

      Brainlab: Imaging a MedTech Future

      By: Regina E. Herzlinger, Gregory P. Licholai and Federica Gabrieli
      Can Brainlab, a privately held firm, compete with giants like Medtronic and Amazon in delivering the Digital Operating Room of the future? The CEO is pondering solutions for secure exchange of medical information, pricing a new robotic imaging device, and reorganizing... View Details
      Keywords: Surgery; Robotics; Health Care; Private Healthcare; Pricing; Technology Platform; Acquisition; Business Growth and Maturation; Growth and Development Strategy; Business Strategy; Corporate Strategy; Corporate Entrepreneurship; Health Care and Treatment; Health; Innovation and Invention; Innovation and Management; Innovation Strategy; Technological Innovation; Applications and Software; Information Infrastructure; Information Technology; Digital Platforms; Health Industry; Europe; Germany; Munich
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      Herzlinger, Regina E., Gregory P. Licholai, and Federica Gabrieli. "Brainlab: Imaging a MedTech Future." Harvard Business School Case 321-087, February 2021. (Revised June 2021.)
      • February 2021 (Revised March 2022)
      • Case

      TikTok in 2020: Super App or Supernova?

      By: Jeffrey F. Rayport, Dan Maher and Dan O'Brien
      TikTok’s parent company, ByteDance, was launched in 2012 around a simple idea – helping users entertain themselves on their smartphones while on the Beijing Subway. In less than a decade, it had become one of the world’s most valuable private companies, with investors... View Details
      Keywords: Business Model; Business Startups; Business Organization; Change Management; Disruption; Cross-Cultural and Cross-Border Issues; Global Strategy; Health Pandemics; Innovation Strategy; Growth and Development Strategy; Growth Management; Brands and Branding; Marketing Strategy; Marketing Channels; Network Effects; Digital Platforms; Product Design; Product Development; Partners and Partnerships; Opportunities; Social Issues; Mobile and Wireless Technology; Internet and the Web; Value Creation; United States; China
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      Rayport, Jeffrey F., Dan Maher, and Dan O'Brien. "TikTok in 2020: Super App or Supernova?" Harvard Business School Case 821-087, February 2021. (Revised March 2022.)
      • February 2021
      • Tutorial

      What is AI?

      By: Tsedal Neeley
      This video explores the elements that constitute artificial intelligence (AI). From its mathematical basis to current advances in AI, this video introduces students to data, tools, and statistical models that make a computer 'intelligent.' Through an explanation of... View Details
      Keywords: Artificial Intelligence; Digital; Technological Innovation; Leadership; AI and Machine Learning; Mathematical Methods
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      Neeley, Tsedal. What is AI? Harvard Business School Tutorial 421-713, February 2021. (https://hbsp.harvard.edu/product/421713-HTM-ENG?Ntt=tsedal%20neeley%20what%20is%20ai.)
      • February 2021
      • Case

      Digital Manufacturing at Amgen

      By: Shane Greenstein, Kyle R. Myers and Sarah Mehta
      This case discusses efforts made by biotechnology (biotech) company Amgen to introduce digital technologies into its manufacturing processes. Doing so is complicated by the fact that the process for manufacturing biologics—or therapeutics made from living cells—is... View Details
      Keywords: Digital Technologies; Change; Change Management; Decision Making; Cost vs Benefits; Decisions; Information; Analytics and Data Science; Innovation and Invention; Innovation and Management; Innovation Leadership; Innovation Strategy; Technological Innovation; Jobs and Positions; Knowledge; Leadership; Organizational Culture; Science; Strategy; Information Technology; Technology Adoption; Biotechnology Industry; Pharmaceutical Industry; United States; California; Puerto Rico; Rhode Island
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      Greenstein, Shane, Kyle R. Myers, and Sarah Mehta. "Digital Manufacturing at Amgen." Harvard Business School Case 621-008, February 2021.
      • February 2021
      • Article

      Platform Diffusion at Temporary Gatherings: Social Coordination and Ecosystem Emergence

      By: Tommy Pan Fang, Andy Wu and David R. Clough
      Software platforms create value by cultivating an ecosystem of complementary products and services. Existing explanations for how a prospective complementor chooses platforms to join assume the complementor has rich information about the range of available platforms.... View Details
      Keywords: Innovation Ecosystems; Technology Diffusion; Hackathon; Contagion; Software Applications; Software Development; Software Engineering; Technology Strategy; Technology Adoption; Technological Innovation; Information Infrastructure; Innovation Strategy; Digital Platforms; Network Effects; Applications and Software; Information Technology; Technology Industry; Computer Industry; Information Technology Industry; Video Game Industry
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      Fang, Tommy Pan, Andy Wu, and David R. Clough. "Platform Diffusion at Temporary Gatherings: Social Coordination and Ecosystem Emergence." Art. 1. Strategic Management Journal 42, no. 2 (February 2021): 233–272. (Lead article.)
      • January 2021 (Revised February 2021)
      • Case

      Tech with a Side of Pizza: How Domino's Rose to the Top

      By: Boris Groysberg, Sarah L. Abbott and Susan Seligson
      After hitting an all-time low in 2008, Domino’s Pizza underwent a vigorous rebranding, product development, and embraced innovative technologies to become the world’s leading international fast-food retailer. Domino’s considered itself as much a tech company as it was... View Details
      Keywords: Digital Marketing; Digital Technology; Innovation; Scaling; Data Analytics; Turnaround; Technological Innovation; Information Technology; Strategy; Management; Marketing; Operations; Human Resources; Entrepreneurship; Change Management; Analysis; Performance; Customers; Growth and Development; Competitive Advantage; Employees; Training; Leadership Development; Food and Beverage Industry; Technology Industry; United States
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      Groysberg, Boris, Sarah L. Abbott, and Susan Seligson. "Tech with a Side of Pizza: How Domino's Rose to the Top." Harvard Business School Case 421-057, January 2021. (Revised February 2021.)
      • December 2020 (Revised January 2022)
      • Supplement

      Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (B)

      By: Linda A. Hill and Emily Tedards
      In 2011, Michael Ku became Pfizer’s Vice President of Global Clinical Supply (GCS) after the company had undergone three large-scale mergers and acquisitions. As Ku and his new leadership team set out to build a proactive, end-to-end, digital and physical clinical... View Details
      Keywords: Digital Technology; Customer-centricity; Innovation; Customer Focus; Talent; Talent Management; Leadership; Innovation and Invention; Transformation; Organizational Culture; Customer Focus and Relationships; Change Management; Talent and Talent Management; Supply Chain; Mission and Purpose
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      Hill, Linda A., and Emily Tedards. "Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (B)." Harvard Business School Supplement 421-037, December 2020. (Revised January 2022.)
      • December 2020
      • Other Article

      Digital Health Care: Empowering Consumers: Q&A with Professor Regina Herzlinger

      By: Regina E. Herzlinger
      Regina Herzlinger, the Nancy R. McPherson Professor of Business Administration, has been studying the health care sector for nearly half a century. In that time, she has seen significant innovation in the field—and she has also seen the powerful sway of the status quo,... View Details
      Keywords: Digital Health; Telemedicine; Wearable Sensors; Health Care and Treatment; Technological Innovation; Health Industry
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      Herzlinger, Regina E. "Digital Health Care: Empowering Consumers: Q&A with Professor Regina Herzlinger." HBS Alumni Bulletin (December 2020).
      • November 2020 (Revised July 2022)
      • Case

      Dell Technologies: Bringing the Cloud to the Ground

      By: Navid Mojir and V. Kasturi Rangan
      The case tells the story of Dell Technologies and its efforts to revitalize its value proposition and escape a commodity trap by acquiring EMC for $67 billion—the largest tech acquisition in history. It also shows the deeply intertwined connections between a company’s... View Details
      Keywords: Value Proposition; Go-to-market; Strategic Positioning; Mergers and Acquisitions; Business Strategy; Marketing Strategy; Technological Innovation; Business Divisions; Information Technology Industry; Computer Industry
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      Mojir, Navid, and V. Kasturi Rangan. "Dell Technologies: Bringing the Cloud to the Ground." Harvard Business School Case 521-036, November 2020. (Revised July 2022.)
      • November 2020
      • Article

      Disrupting the Disruptors or Enhancing Them? How Blockchain Re‐Shapes Two‐Sided Platforms

      By: Daniel Trabucchi, Antonella Moretto, Tommaso Buganza and Alan MacCormack
      The importance of platform‐based businesses in the modern economy is growing continuously and becoming increasingly relevant. Specifically, the deployment of digital technologies has enhanced the applicability of two‐sided business models, enabling companies to act not... View Details
      Keywords: Blockchain; Two-Sided Platforms; Business Model; Innovation and Invention; Technological Innovation
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      Trabucchi, Daniel, Antonella Moretto, Tommaso Buganza, and Alan MacCormack. "Disrupting the Disruptors or Enhancing Them? How Blockchain Re‐Shapes Two‐Sided Platforms." Journal of Product Innovation Management 37, no. 6 (November 2020): 552–574.
      • November–December 2020
      • Article

      Rethinking the On-Demand Workforce

      By: Joseph B. Fuller, Manjari Raman, Allison Bailey and Nithya Vaduganathan
      As companies struggle with chronic skills shortages and changing labor demographics, a new generation of talent platforms, offering on-demand access to highly trained workers, has begun to help. These platforms include marketplaces for premium expertise (such as Toptal... View Details
      Keywords: Talent Acquisition; Platforms; Skilled Labor Recruitment; Gig Economy; Talent and Talent Management; Selection and Staffing; Internet and the Web; Strategy; Digital Platforms
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      Fuller, Joseph B., Manjari Raman, Allison Bailey, and Nithya Vaduganathan. "Rethinking the On-Demand Workforce." Harvard Business Review 98, no. 6 (November–December 2020): 96–103.
      • October 2020
      • Supplement

      OpenIDEO (B)

      By: Karim R. Lakhani, Anne-Laure Fayard, Manos Gkeredakis and Jin Hyun Paik
      In the midst of 2020, as the coronavirus pandemic was unfolding, OpenIDEO—an online open innovation platform focused on design-driven solutions to social issues—rapidly launched a new challenge to improve access to health information, empower communities to stay safe... View Details
      Keywords: Innovation Competitions; IDEO; Contests; Contest Design; Platforms And Ecosystems; Open Innovation; Open And User Innovation Strategy; Diversity; Design; Social Entrepreneurship; Global Range; Collaborative Innovation and Invention; Innovation Strategy; Organizational Change and Adaptation; Social and Collaborative Networks; Health Pandemics; Health; Information; Business and Community Relations; Digital Platforms
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      Lakhani, Karim R., Anne-Laure Fayard, Manos Gkeredakis, and Jin Hyun Paik. "OpenIDEO (B)." Harvard Business School Supplement 621-058, October 2020.
      • September 2020 (Revised May 2024)
      • Case

      Hot Wheels: Launching The Mixed Play Experience

      By: Elie Ofek, Andres Terech and Nicole Tempest Keller
      Chris Down, Global Brand General Manager for Hot Wheels, and his team from the Advanced Play Group within Mattel, Inc., had developed an entirely new “mixed play” product experience that blended familiar Hot Wheels play in the physical world with breakthrough play in... View Details
      Keywords: Toys; Go-to-market Strategy; Product Development; Technological Innovation; Product Launch; Product Positioning; Decision Making; Marketing; Strategy; Los Angeles
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      Ofek, Elie, Andres Terech, and Nicole Tempest Keller. "Hot Wheels: Launching The Mixed Play Experience." Harvard Business School Case 521-017, September 2020. (Revised May 2024.)
      • September 2020 (Revised December 2020)
      • Case

      Hot Wheels at Mattel: Reinventing the Wheel

      By: Elie Ofek, Andres Terech and Nicole Tempest Keller
      In 2017, Chris Down, Global Brand General Manager for Hot Wheels, and his team from the Advanced Play Group within Mattel, Inc., were considering which innovation path to pursue in order to "future proof" the Hot Wheels franchise going forward. Hot Wheels was the... View Details
      Keywords: Toys; Industry Evolution; Innovation Strategy; Product Development; Growth and Development Strategy; Technological Innovation; Organizational Change and Adaptation; Decision Making; Digital Transformation
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      Ofek, Elie, Andres Terech, and Nicole Tempest Keller. "Hot Wheels at Mattel: Reinventing the Wheel." Harvard Business School Case 521-015, September 2020. (Revised December 2020.)
      • September 2020
      • Case

      True North: Pioneering Analytics, Algorithms and Artificial Intelligence

      By: Karim R. Lakhani, Kairavi Dey and Hannah Mayer
      True North was a private equity fund that specialized in the growth and buyout of mid-market, India-centric companies. The leadership team initially believed that technology was not core to traditional businesses and steered clear of new age technology-oriented... View Details
      Keywords: Artificial Intelligence; Information Technology; Management; Operations; Organizations; Leadership; Innovation and Invention; Business Model; AI and Machine Learning; Computer Industry; Technology Industry
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      Lakhani, Karim R., Kairavi Dey, and Hannah Mayer. "True North: Pioneering Analytics, Algorithms and Artificial Intelligence." Harvard Business School Case 621-042, September 2020.
      • September 2020
      • Article

      Regulatory Sandboxes: A Cure for mHealth Pilotitis?

      By: Abhishek Bhatia, Rahul Matthan, Tarun Khanna and Satchit Balsari
      Mobile health (mHealth) and related digital health interventions in the past decade have not always scaled globally as anticipated earlier despite large investments by governments and philanthropic foundations. The implementation of digital health tools has suffered... View Details
      Keywords: COVID-19; mHealth; Digital Health; Design Thinking; Regulation; Intervention; Regulatory Sandbox; Health Care and Treatment; Technological Innovation; Design; Governing Rules, Regulations, and Reforms; India
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      Bhatia, Abhishek, Rahul Matthan, Tarun Khanna, and Satchit Balsari. "Regulatory Sandboxes: A Cure for mHealth Pilotitis?" Journal of Medical Internet Research 22, no. 9 (September 2020).
      • July 2020
      • Technical Note

      Digital Natives Growing Without a Sales Force

      By: Das Narayandas, Michael Norris and Amram Migdal
      This brief case describes the rise of so-called digital natives (also called born-in-digital) in the 2000s and 2010s that successfully grew without a sales force. The case highlights the emergence of business-to-business Internet and cloud-based companies and their... View Details
      Keywords: Government Administration; Crisis Management; Health; Health Pandemics; Innovation and Invention; Innovation Leadership; Innovation Strategy; Technological Innovation; Social Issues; Information Technology; Mobile and Wireless Technology; Applications and Software; Technology Adoption; Information Technology Industry; Australia; North and Central America; United States; Illinois; Chicago; California; San Francisco
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      Narayandas, Das, Michael Norris, and Amram Migdal. "Digital Natives Growing Without a Sales Force." Harvard Business School Technical Note 521-019, July 2020.
      • July 2020 (Revised January 2021)
      • Case

      Vineet Nayar and Sampark Foundation: Frugal Innovation at Scale (A)

      By: Linda A. Hill and Emily Tedards
      In 2005, Vineet Nayar, the former CEO and Vice Chairman of HCL Technologies, and his wife, Anupama Nayar, committed $100 million of their personal wealth to found Sampark Foundation — a grant-making philanthropy with a mission to transform learning outcomes for 20... View Details
      Keywords: Organizational Behavior; Cultural Change; Digital; Innovation; Experimentation; Metrics; Education Reform; Non-profit; Frugal Innovation; Scale; Ecosystem; Government; Education; Social Enterprise; Leadership; Leading Change; Change Management; Organizational Culture; Innovation Leadership; Nonprofit Organizations; Growth and Development Strategy; Information Technology; Digital Transformation; India
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      Hill, Linda A., and Emily Tedards. "Vineet Nayar and Sampark Foundation: Frugal Innovation at Scale (A)." Harvard Business School Case 421-015, July 2020. (Revised January 2021.)
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