Technological And Scientific Innovation - Publications - Faculty & Research - Harvard Business School

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April 2020
Article

Technological Leadership (de)Concentration: Causes in Information and Communication Technology Equipment

By: Yasin Ozcan and Shane Greenstein

Using patent data from 1976 to 2010 as indicators of inventive activity, we determine the concentration level of where inventive ideas originate and then examine how and why those concentrations change over time. The analysis finds pervasive deconcentration in every... View Details

Keywords: Deconcentration; Technological Innovation; Innovation Leadership; Patents; Market Entry and Exit; Telecommunications Industry

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September 2014
Case

Pfizer's Centers for Therapeutic Innovation (CTI)

By: Gary Pisano, James Weber and Kait Szydlowski

In 2010, Pfizer established four small research units in New York, Boston, San Francisco, and San Diego located close to several premier Academic Medical Centers (AMCs), or hospitals with adjoining medical schools. The goal of these units was to redesign collaboration... View Details

Keywords: Drug Development; Academic Collaboration; Research And Development; Innovation; Translational Research; Management; Operations; Problems and Challenges; Research; Science; Information Technology; Strategy; Biotechnology Industry; Pharmaceutical Industry; North and Central America; Europe; Asia

May 2021
Case

Inclusive Innovation at Mass General Brigham

By: Katherine Baldiga Coffman and Olivia Hull

Massachusetts General Brigham (MGB) Chief Innovation Officer Christopher Coburn had overseen a period of exciting transformation and growth in healthcare innovation at MGB. In November 2019, the health system was the largest recipient of National Institutes of Health... View Details

2019
Article

Overcoming Cultural Resistance to Open Source Innovation

By: John Winsor, Jin Hyun Paik, Michael Tushman and Karim R. Lakhani

Purpose: This article offers insight on how to effectively help incumbent organizations prepare for global business shifts to open source and digital business models.
Design/methodology/approach: Discussion related to observation, experience and case studies... View Details

Keywords: Open Source Innovation; Organizational Culture; Organizational Change and Adaptation; Business Model; Technological Innovation; Collaborative Innovation and Invention

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Research Summary

International Competitiveness in High Technology and Science Based Sectors

By: Gary P. Pisano

This research project examines shifts in competitive capabilities of companies and countries in high technology and science based businesses. It is particularly concerned with the potential loss of such capabilities in various industrial sectors in the... View Details

August 2022
Article

Regulatory Considerations to Keep Pace with Innovation in Digital Health Products

By: John Torous, Ariel Dora Stern and Florence T. Bourgeois

Rapid innovation and proliferation of software as a medical device have accelerated the clinical use of digital technologies across a wide array of medical conditions. Current regulatory pathways were developed for traditional (hardware) medical devices and offer a... View Details

Keywords: Emerging Technologies; Governing Rules, Regulations, and Reforms; Innovation and Invention; Medical Devices and Supplies Industry

January 2016
Case

Open Innovation at Fujitsu (A)

By: Amy C. Edmondson and Jean-François Harvey

This case study examines the open innovation journey at Fujitsu, a global information and communication technology company. The case ends with the location decision between Tokyo, Japan, downtown San Francisco or Sunnyvale, California, regarding establishing a small... View Details

April 2010
Teaching Note

Wyeth Pharmaceuticals: Spurring Scientific Creativity with Metrics

By: Robert S. Huckman

Teaching Note for [607008]. View Details

Keywords: Restructuring; Decisions; Innovation and Invention; Research and Development; Health Industry; Pharmaceutical Industry

January 2015 (Revised January 2017)
Case

Curriculum Associates: Turning the Page from Tradition to Innovation

By: John J-H Kim and Christine S. An

Set in Fall 2014, the traditional textbook publishing industry is being transformed by technological innovations and new student achievement standards. This case chronicles how Rob Waldron, CEO, and his team bring Curriculum Associates (CA), a traditional supplemental... View Details

Keywords: Education Technology; SaaS; Turnaround; Textbook Publishing; Innovation; Sales Cycle; HR Strategy; Privately-funded Businesses; Sustainable Growth; Product Development Strategy; Organizational Change and Adaptation; Technological Innovation; Competitive Advantage; Publishing Industry

2007
Other Unpublished Work

Implementing Technology

By: Diego Comin and Bart Hobijn

We introduce a tractable model of endogenous growth in which the returns to innovation are determined by the technology adoption decisions of the users of new technologies. Technology adoption involves an implementation investment that determines the initial... View Details

Keywords: Learning; Investment; Investment Return; Innovation and Invention; Growth and Development Strategy; Performance Productivity; Technology Adoption

30 Sep 2009
Working Paper Summaries

Breakthrough Inventions and Migrating Clusters of Innovation

Keywords: by William R. Kerr; Technology

May–June 2025
Article

Balancing Digital Safety and Innovation

By: Tomomichi Amano and Tomomi Tanaka

Designers of consumer-facing digital products have tended to focus on novelty and speed (“move fast and break things”). They’ve spent more effort on innovating than on anticipating how customers—and bad actors—might engage with products. But as digital products become... View Details

Keywords: Technological Innovation; Cybersecurity; Demand and Consumers; Safety

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1985
Working Paper

Sequential Innovation and Market Structure

By: Jerry R. Green and Jean-Jacques Laffont

This paper concerns the introduction of a sequence of new, higher-quality durable products in a market in which there already exists a lower-quality substitute. The product has the further attribute that a real resource cost is incurred at the time a higher-quality... View Details

October 11, 2016
Article

Innovation Network

By: Daron Acemoglu, Ufuk Akcigit and William R. Kerr

Technological progress builds upon itself, with the expansion of invention in one domain propelling future work in linked fields. Our analysis uses 1.8 million U.S. patents and their citation properties to map the innovation network and its strength. Past innovation... View Details

Keywords: Innovation and Invention; Networks; Patents

February 2013
Article

Sustaining Innovation When Outsourcing Components in Multi-technology, Multi-component Systems

By: Ian Mackenzie and Casimer DeCusatis

Firms producing multi-technology, multi-component systems are increasingly outsourcing selected components to achieve both reduced cost and enhanced innovation benefits. Given typical inter-dependence between innovation at the system and component levels, an important... View Details

Keywords: Innovation; Job Cuts and Outsourcing; Alignment; Innovation and Invention; Information Technology Industry

01 Dec 2009
Working Paper Summaries

Modeling a Paradigm Shift: From Producer Innovation to User and Open Collaborative Innovation

Keywords: by Carliss Y. Baldwin & Eric von Hippel

January 2009 (Revised June 2024)
Case

Design Thinking and Innovation at Apple

By: Stefan Thomke and Barbara Feinberg

Describes Apple's approach to innovation, management, and design thinking. For several years, Apple has been ranked as the most innovative company in the world, but how it has achieved such success remains mysterious because of the company's obsession with secrecy.... View Details

Keywords: Design; Corporate Entrepreneurship; Innovation and Management; Product Design; Product Development; Research and Development; Creativity; Technology Industry

2015
Chapter

Innovating without Information Constraints: Organization, Communities, and Innovation when Information Costs Approach Zero

By: Elizabeth J. Altman, Frank Nagle and Michael Tushman

Innovation has traditionally taken place within an organization's boundaries and/or with selected partners. This Chandlerian approach to innovation has been rooted in transaction costs, organizational boundaries, and information processing challenges associated with... View Details

Keywords: Knowledge Sharing; Cost; Innovation and Management; Collaborative Innovation and Invention

2025
Working Paper

How to Choose Among Technologies with Learning Curves: Making Better Investment Decisions

By: Christian Kaps and Arielle Anderer

Learning curves, the fact that technologies improve as a function of cumulative experience or investment, are desirable-think inexpensive solar panels or higher performing semiconductors. But, for firms that need to pick one technology among several candidates, such as... View Details

Keywords: Learning Curve; Technology; Innovation; Batteries; Energy Storage; Sequential Decision Making; TELCO; Exploration; Exploitation; Problems and Challenges; Cost vs Benefits; Technology Adoption; Battery Industry

22 Jul 2010
Working Paper Summaries

Business Model Innovation and Competitive Imitation

Keywords: by Ramon Casadesus-Masanell & Feng Zhu

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