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      • October 2023 (Revised March 2024)
      • Case

      KOKO Networks: Bridging Energy Transition and Affordability with Carbon Financing

      By: George Serafeim, Siko Sikochi and Namrata Arora
      The problem was massive: two million hectares of African forests were lost annually to charcoal production for cooking, an area equivalent to 13 times Greater London, resulting in one billion tons of carbon emissions yearly. At the same time, an estimated 700,000... View Details
      Keywords: Clean Tech; Digital; Carbon Credits; Carbon Offsetting; Climate Change; Entrepreneurship; Energy Sources; Environmental Sustainability; Health; Market Design; Business Startups; Transition; Environmental Regulation; Policy; Energy Industry; Consumer Products Industry; Africa; Kenya; Rwanda
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      Serafeim, George, Siko Sikochi, and Namrata Arora. "KOKO Networks: Bridging Energy Transition and Affordability with Carbon Financing." Harvard Business School Case 124-022, October 2023. (Revised March 2024.)
      • October 2023 (Revised November 2023)
      • Case

      Rheaply: Circularity For Every Business

      By: Rembrand Koning and Alicia Dadlani
      In March 2023, Garry Cooper, cofounder and CEO of Chicago-based Rheaply, needed to demonstrate that Rheaply’s expanded vision could translate into building cash flows and metrics needed to raise a Series B and turn the business into a model for financial and... View Details
      Keywords: Business Startups; Social Entrepreneurship; Technological Innovation; Environmental Sustainability; Entrepreneurial Finance; Technology Industry; Green Technology Industry; United States; Illinois; Chicago
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      Koning, Rembrand, and Alicia Dadlani. "Rheaply: Circularity For Every Business." Harvard Business School Case 724-351, October 2023. (Revised November 2023.)
      • October 2023
      • Supplement

      Rheaply: Circularity For Every Business Supplement 1

      By: Rembrand Koning and Alicia Dadlani
      Pitch deck explaining the early vision of the company that was presented by the CEO to potential investors. View Details
      Keywords: Business Startups; Social Entrepreneurship; Entrepreneurial Finance; Mission and Purpose; United States; Chicago; Illinois
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      Koning, Rembrand, and Alicia Dadlani. "Rheaply: Circularity For Every Business Supplement 1." Harvard Business School PowerPoint Supplement 724-354, October 2023.
      • October 2023
      • Supplement

      Rheaply: Circularity For Every Business Supplement 2

      By: Rembrand Koning and Alicia Dadlani
      Pitch deck explaining the later vision of the company that was presented by the CEO to potential investors. View Details
      Keywords: Business Startups; Social Entrepreneurship; Entrepreneurial Finance; Mission and Purpose; Technology Industry; Green Technology Industry; United States; Illinois; Chicago
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      Koning, Rembrand, and Alicia Dadlani. "Rheaply: Circularity For Every Business Supplement 2." Harvard Business School PowerPoint Supplement 724-385, October 2023.
      • October 2023 (Revised March 2024)
      • Case

      Fantuan

      By: Feng Zhu and David Lane
      In 2023, CEO Randy Wu was considering the optimal growth strategy for Fantuan, a restaurant food delivery platform that had expanded from its 2014 founding in Vancouver, Canada to serve the Chinese demand for Asian cuisine in urban markets across Australia, Canada, the... View Details
      Keywords: Business Startups; Customer Focus and Relationships; Diasporas; Entrepreneurship; Digital Platforms; Growth Management; Business Strategy; Diversification; Expansion; Growth and Development Strategy; Service Industry; Food and Beverage Industry; United States; Canada; United Kingdom; Australia
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      Zhu, Feng, and David Lane. "Fantuan." Harvard Business School Case 624-023, October 2023. (Revised March 2024.)
      • October 2023
      • Case

      Vida Health: Transforming Chronic Disease Treatment

      By: William Sahlman and Nicole Tempest Keller
      San Francisco based Vida Health, founded by Stephanie Tilenius, former vice president of Commerce and Payments at Google, was a B2B digital health startup focused on the treatment of cardiometabolic conditions, such as diabetes and obesity. Its innovative digital... View Details
      Keywords: Corporate Strategy; Growth and Development Strategy; Demand and Consumers; Health Care and Treatment; Product Marketing; Risk and Uncertainty; Technological Innovation; Health Industry; Technology Industry; United States; California; San Francisco
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      Sahlman, William, and Nicole Tempest Keller. "Vida Health: Transforming Chronic Disease Treatment." Harvard Business School Case 824-001, October 2023.
      • October 2023
      • Case

      Foodology: Creating a Virtual Restaurant Group in Latin America

      By: Rembrand M. Koning, Jorge Tamayo and Jenyfeer Martínez Buitrago
      In April 2020, Daniela Izquierdo (HBS, 2019) and Juan Guillermo Azuero (HBS, 2019), awaited the results of Harvard Business School’s Alumni New Venture Competition. Operating since September 2019, Foodology, a Colombian food-tech startup in the cloud kitchen segment,... View Details
      Keywords: Business Startups; Business Model; Entrepreneurship; Food and Beverage Industry; Latin America; South America; Colombia
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      Koning, Rembrand M., Jorge Tamayo, and Jenyfeer Martínez Buitrago. "Foodology: Creating a Virtual Restaurant Group in Latin America." Harvard Business School Case 724-392, October 2023.
      • October 2023 (Revised November 2023)
      • Case

      Sprout Solutions

      By: Jeffrey J. Bussgang, Bonnie Yining Cao and Dawn H. Lau
      Husband-and-wife co-founders Patrick and Alexandria Gentry had built Sprout Solutions to be one of the biggest Software-as-a-Service human resources management platforms in the Philippines, guided by the mission to "impact the life of every Filipino by improving... View Details
      Keywords: Software; Startup; Technology Ventures; Human Resources; Management; Growth and Development Strategy; Emerging Markets; Business Startups; Applications and Software; Venture Capital; Philippines
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      Bussgang, Jeffrey J., Bonnie Yining Cao, and Dawn H. Lau. "Sprout Solutions." Harvard Business School Case 824-052, October 2023. (Revised November 2023.)
      • October 2023 (Revised February 2024)
      • Case

      Loris

      By: Shunyuan Zhang, Das Narayandas, Stacy Straaberg and David Lane
      In December 2022, Loris’s executive team considered their go-to-market strategy. Loris was an artificial intelligence (AI) software startup for the customer service industry with two products on the market: 1) Agent Assist which provided customer service agents (CSAs)... View Details
      Keywords: Decisions; Growth and Development Strategy; Product Launch; Product Positioning; Business Strategy; Competitive Strategy; Business Startups; AI and Machine Learning; Applications and Software; Marketing Strategy; Sales; Technology Industry; United States
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      Zhang, Shunyuan, Das Narayandas, Stacy Straaberg, and David Lane. "Loris." Harvard Business School Case 524-010, October 2023. (Revised February 2024.)
      • 2025
      • Working Paper

      Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance

      By: Justine Boudou and Maria Roche
      In this paper, we examine how a startup’s knowledge foundations—embedded in its core technology—influence its performance in the exit market. Using a dataset of 1,006 biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1) the degree of... View Details
      Keywords: Firm Performance; Knowledge Foundations; Exits; Academic Startups; Inventor-founder; Specialized Scientific Knowledge; Competitive Advantage; Value Creation; Research; Information Publishing; Business Startups; Entrepreneurship
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      Boudou, Justine, and Maria Roche. "Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance." Harvard Business School Working Paper, No. 24-021, October 2023. (Revised February 2025.)
      • September 2023 (Revised November 2023)
      • Case

      Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab

      By: George Serafeim and Michael Norris
      In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company as he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in... View Details
      Keywords: Business Model; Green Technology; Goods and Commodities; Growth and Development Strategy; Science-Based Business; Entrepreneurship; Plant-Based Agribusiness; Business Startups; Decisions; Technological Innovation; Production; Agriculture and Agribusiness Industry; Technology Industry; Boston; Sao Paulo
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      Serafeim, George, and Michael Norris. "Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab." Harvard Business School Case 124-017, September 2023. (Revised November 2023.)
      • September 2023 (Revised January 2025)
      • Case

      To Found or to Cofound? That is the Question

      By: Christina Wallace and Jo Tango
      Entrepreneurs often struggle with the question of whether to found solo or alongside one or more cofounders. This case is comprised of three vignettes detailing common founding scenarios: the first-time technical founder; the serial commercial founder; and the MBA... View Details
      Keywords: Business Startups; Decisions; Entrepreneurship; Partners and Partnerships
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      Wallace, Christina, and Jo Tango. "To Found or to Cofound? That is the Question." Harvard Business School Case 824-034, September 2023. (Revised January 2025.)
      • September 2023
      • Case

      Ada: Cultivating Investors

      By: Reza Satchu and Patrick Sanguineti
      Mike Murchison, co-founder and CEO of Ada, has an enviable dilemma. Launched in 2016 by Murchison and his co-founder David Hariri, Ada is an AI-native company that aims to revolutionize how businesses approach customer service. The company has already attracted a buzz,... View Details
      Keywords: Founder; Fundraising; Business Startups; Decisions; Entrepreneurship; Venture Capital; AI and Machine Learning; Technology Industry
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      Satchu, Reza, and Patrick Sanguineti. "Ada: Cultivating Investors." Harvard Business School Case 824-090, September 2023.
      • September 2023
      • Case

      DocSend: A Path off the Plateau?

      By: Thomas R. Eisenmann and Jeffrey Huizinga
      Recounts how the leaders of DocSend, an early-stage startup that offered tools for sharing files online, searched for a viable business model and weighed tradeoffs in transitioning from a sales-led to a product-led "go-to-market" approach. View Details
      Keywords: Technology; Start-up; Growth; Business Model; Business Startups; Sales; Growth and Development Strategy; Technology Industry
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      Eisenmann, Thomas R., and Jeffrey Huizinga. "DocSend: A Path off the Plateau?" Harvard Business School Case 824-038, September 2023.
      • September 2023 (Revised December 2023)
      • Case

      TetraScience: Noise and Signal

      By: Thomas R. Eisenmann and Tom Quinn
      In 2019, TetraScience CEO “Spin” Wang needed advice. Five years earlier, he had cofounded a startup that saw early success with a hardware product designed to help laboratory scientists in the biotechnology and pharmaceutical spaces more easily collect data from... View Details
      Keywords: Entrepreneurship; Business Growth and Maturation; Business Organization; Restructuring; Forecasting and Prediction; Digital Platforms; Analytics and Data Science; AI and Machine Learning; Organizational Structure; Network Effects; Competitive Strategy; Biotechnology Industry; Pharmaceutical Industry; United States; Boston
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      Eisenmann, Thomas R., and Tom Quinn. "TetraScience: Noise and Signal." Harvard Business School Case 824-024, September 2023. (Revised December 2023.)
      • September 2023
      • Case

      Derek Aguirre

      By: Leslie Perlow and Hannah Weisman
      Derek Aguirre is the executive director of a nonprofit organization in Detroit, Michigan that uses the sport of squash as a vehicle to support young people in low-income urban areas. The case discusses his path to pursue meaningful work and his reflections on the... View Details
      Keywords: Personal Development and Career; Job Search; Happiness; Well-being; Work-Life Balance; Nonprofit Organizations; Social Enterprise; Business Startups; Sports; Education; Mission and Purpose; Education Industry; Sports Industry; Service Industry; United States; Boston; Detroit
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      Perlow, Leslie, and Hannah Weisman. "Derek Aguirre." Harvard Business School Case 424-019, September 2023.
      • September 2023 (Revised April 2024)
      • Case

      Atomwise: Strategic Opportunities in AI for Pharma

      By: Satish Tadikonda
      Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural... View Details
      Keywords: Business Model; Business Startups; AI and Machine Learning; Science-Based Business; Technological Innovation; Biotechnology Industry; Pharmaceutical Industry
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      Tadikonda, Satish. "Atomwise: Strategic Opportunities in AI for Pharma." Harvard Business School Case 824-043, September 2023. (Revised April 2024.)
      • September 2023
      • Case

      Healthy.io: The Negotiation for the Medical Selfie

      By: Amit Goldenberg and Kumba Sennaar
      Healthy.io, an Israeli digital health company, prepares to enter the U.S. market with its chronic kidney disease test. A product safety approval is delayed, putting the company’s cash runway at risk. How should the CEO negotiate his offer to insurance companies ahead... View Details
      Keywords: Negotiation; Entrepreneurship; Venture Capital; Operations; Business Startups; Market Entry and Exit; Health Industry; Israel; United Kingdom; United States
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      Goldenberg, Amit, and Kumba Sennaar. "Healthy.io: The Negotiation for the Medical Selfie." Harvard Business School Case 924-001, September 2023.
      • September 2023 (Revised July 2024)
      • Case

      Honest Jobs: A Path to Redemption

      By: Paul A. Gompers and Jeffrey Barkas
      Founded by a formerly incarcerated job seeker, Honest Jobs' mission is to be the hub where people with criminal records come to build careers and employers come to find great talent. Honest Jobs faced early challenges as a two-sided platform for justice-involved job... View Details
      Keywords: Business Startups; Venture Capital; Recruitment; Entrepreneurial Finance; Selection and Staffing; Digital Platforms; Job Search; Mission and Purpose; Expansion; Employment Industry; United States; Colorado; Ohio; Texas
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      Gompers, Paul A., and Jeffrey Barkas. "Honest Jobs: A Path to Redemption." Harvard Business School Case 224-010, September 2023. (Revised July 2024.)
      • September 2023 (Revised January 2024)
      • Case

      RightHand Robotics: Choosing the First Market

      By: Thomas R. Eisenmann and Stacy Straaberg
      In early 2015, RightHand Robotics’s (RHR) leadership faced a set of decisions in commercializing the startup’s robotic picking solution. RHR’s central product was the RightPick integrated robotic picking system which featured a robotic arm, a three-fingered robotic... View Details
      Keywords: Business Startups; Market Entry and Exit; Product; Research and Development; Business Strategy; Commercialization; Information Infrastructure; Technological Innovation; Manufacturing Industry; Technology Industry; United States; Massachusetts
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      Eisenmann, Thomas R., and Stacy Straaberg. "RightHand Robotics: Choosing the First Market." Harvard Business School Case 824-006, September 2023. (Revised January 2024.)
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