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  • September 15, 2021
  • Article

Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map

By: Andrea Blasco, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani and Aravind Subramanian
A recurring problem in biomedical research is how to isolate signals of distinct populations (cell types, tissues, and genes) from composite measures obtained by a single analyte or sensor. Existing computational deconvolution approaches work well in many specific... View Details
Keywords: Deconvolution; Methods; Open Innovation Competition; Genomics; Research; Innovation and Invention
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  • 2021
  • Working Paper

rTSR: Properties, Determinants, and Consequences of Benchmark Choice

By: Paul Ma, Jee-Eun Shin and Charles C.Y. Wang
We develop a measurement-error framework for assessing the quality of relative-performance metrics designed to filter out the systematic component of performance and analyze relative total shareholder return (rTSR)—the predominant metric market participants use to... View Details
Keywords: Relative TSR; Relative Performance Evaluation; Systematic Risk; Board Of Directors; Compensation Consultants; Style Effects; Executive Compensation; Performance Evaluation; Corporate Governance
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  • 2009
  • Book

Let Me Explain: Eugene G. Fubini's Life in Defense of America

By: David G. Fubini
There is no necessary relationship between fame and power, and great influence is often wielded in willful obscurity. So it was with the irascible, indomitable Eugene Fubini. A physics prodigy who fled Italy when the fascists came to power, his searing intelligence and... View Details
Keywords: Biography; Personal Development and Career; National Security; United States
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  • February 2017
  • Article

Resident Networks and Corporate Connections: Evidence from World War II Internment Camps

By: Lauren Cohen, Umit Gurun and Christopher J. Malloy
We demonstrate that simply by using the ethnic makeup surrounding a firm’s location, we can predict, on average, which trade links are valuable for firms. Using customs and port authority data on the international shipments of all U.S. publicly traded firms, we show... View Details
Keywords: Information Networks; Trade Links; Firm Behavior; Networks; Geographic Location; Ethnicity; Organizations; Trade
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  • 2006
  • Case

Strategies for Preventing a Knowledge-Loss Crisis

When employees leave an organization, they depart with more than what they know; they also leave with critical knowledge about who they know. Thus, the departure of key people can significantly affect the relationship structure and consequent functioning of an... View Details
Keywords: Analytics; Networks; Knowledge Management; Resignation and Termination
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    Market Power in Mortgage Lending and the Transmission of Monetary Policy

    We present evidence that high concentration in mortgage lending reduces the sensitivity of mortgage rates and refinancing activity to mortgage-backed security (MBS) yields. We isolate the direct effect of concentration and rule out alternative explanations in two ways.... View Details
    • 20 Mar 2008
    • Working Paper Summaries

    Sell Side School Ties

    Keywords: by Lauren H. Cohen, Andrea Frazzini & Christopher J. Malloy; Financial Services
    • 2020
    • Working Paper

    How Competition Affects Contributions to Open Source Platforms: Evidence from OpenStreetMap and Google Maps

    By: Abhishek Nagaraj and Henning Piezunka
    Open source platforms often face competition from commercial alternatives and yet we lack an understanding of whether and how commercial competition affects contributions to open source platforms. We study how contributions to OpenStreetMap, a widely-used open source... View Details
    Keywords: Open Source Platforms; Contributions; Competitive Entry; Impact; Multi-Sided Platforms; Competition
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    • Web

    Faculty & Research

    isolate the direct effects of tariff changes across product categories and trading partners. Our analysis reveals rapid pricing responses, though their magnitude remains modest relative to the announced tariff rates and varies by country... View Details
    • 26 Apr 2012
    • Working Paper Summaries

    What Makes a Critic Tick? Connected Authors and the Determinants of Book Reviews

    Keywords: by Loretti I. Dobrescu, Michael Luca & Alberto Motta; Information; Publishing
    • 24 Jan 2024
    • Op-Ed

    Why Boeing’s Problems with the 737 MAX Began More Than 25 Years Ago

    in design and production with its newest jumbo jet, the 787 Dreamliner. Such frequent, repeated crises point to a deeper issue than isolated engineering mishaps. The underlying cause of these issues is a leadership failure that has... View Details
    Keywords: by Bill George; Air Transportation; Transportation; Aerospace
    • 21 Jan 2014
    • First Look

    First Look: January 21

    Publications August 2013 Journal of Economic Behavior & Organization Awards Unbundled: Evidence from a Natural Field Experiment By: Ashraf, Nava, Oriana Bandiera, and Scott Lee Abstract—Organizations often use non-monetary awards to incentivize performance. Awards... View Details
    Keywords: Sean Silverthorne
    • 31 Mar 2010
    • Working Paper Summaries

    When Open Architecture Beats Closed: The Entrepreneurial Use of Architectural Knowledge

    Keywords: by Carliss Y. Baldwin
    • 17 Jan 2008
    • Working Paper Summaries

    Competition in Modular Clusters

    Keywords: by Carliss Y. Baldwin & C. Jason Woodard; Consulting; Communications; Telecommunications; Pharmaceutical
    • Research Summary

    Research

    Professor Karmarkar's research in consumer behavior develops theory-driven frameworks “from the brain up”. In particular, using a combination of consumer psychology, behavioral economics, and insights from neuroscience, she investigates the factors that consciously... View Details

      Do Networks Help People To Manage Poverty?

      Social support networks can provide much-needed emotional, material, and financial help for people living in poverty, yet little is known about how social capital is created and augmented within such networks. Further, these networks can be eroded by sustained... View Details

      • 06 Jan 2015
      • Working Paper Summaries

      Henry A. Kissinger as Negotiator: Background and Key Accomplishments

      Keywords: by James Sebenius & Laurence A. Green
      • 12 Oct 2010
      • Working Paper Summaries

      Crashes and Collateralized Lending

      Keywords: by Jakub W. Jurek & Erik Stafford; Banking; Financial Services
      • 30 May 2013
      • Working Paper Summaries

      Non-Standard Matches and Charitable Giving

      Keywords: by Michael Sanders, Sarah Smith & Michael I. Norton
      • December 2013
      • Case

      Bruce Allyn: Negotiating with the KGB (A)

      By: James K. Sebenius
      Isolated by the KGB in Moscow, Harvard graduate student Bruce Allyn faces high-pressure negotiation tactics to recruit him for the Soviet spy agency. At the tense height of the Cold War, with CIA agents systematically being exposed and executed in Russia, Allyn was... View Details
      Keywords: Negotiation; Bargaining; Hard Bargaining; KGB; Espionage; Spying; War; National Security; Alliances; Ethics; Negotiation Tactics; Decision Choices and Conditions; Negotiation Participants; Negotiation Offer; Cambridge; Moscow; Soviet Union
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