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February 2021
Case

Digital Manufacturing at Amgen

By: Shane Greenstein, Kyle R. Myers and Sarah Mehta

This case discusses efforts made by biotechnology (biotech) company Amgen to introduce digital technologies into its manufacturing processes. Doing so is complicated by the fact that the process for manufacturing biologics—or therapeutics made from living cells—is... View Details

November 2020
Supplement

Valuing Celgene's CVR

By: Benjamin C. Esty and Daniel Fisher

When Bristol-Myers Squibb (BMS) acquired Celgene Corporation in November 2019, Celgene shareholders received cash, BMS stock, and a contingent value right (CVRs) that would pay $9 if the U.S. Food and Drug Administration (FDA) approved three of Celgene’s late stage... View Details

Keywords: Mergers and Acquisitions; Value; Valuation; Judgments; Decision Making; Cash Flow; Financial Instruments; Cognition and Thinking; Pharmaceutical Industry; Pharmaceutical Industry; United States

January 2018
Teaching Note

BeiGene

By: Willy Shih and Jimmy Zhang

Teaching Note for HBS No. 618-033. View Details

Keywords: Biotechnology; Drug Development; Corporate Strategy; Business Startups; Technological Innovation; Situation or Environment; Pharmaceutical Industry; Pharmaceutical Industry; China

June 2014
Supplement

Merrimack Pharmaceuticals, Inc. (B)

By: Amy C. Edmondson, Bethany Gerstein and Melissa Valentine

In 2006, the leadership team at Merrimack Pharmaceuticals, Inc. had to decide whether to keep its R&D organization in functional departments or restructure it into interdisciplinary teams. This case follows the outcomes of this decision from 2006 to mid-2014, and... View Details

Keywords: Organizational Design; Groups and Teams; Collaborative Innovation and Invention; Research and Development; Pharmaceutical Industry; Pharmaceutical Industry

January 2014 (Revised June 2015)
Teaching Note

Amgen Inc: Pursuing Innovation and Imitation? (A), (B)

By: Ian Mackenzie

Keywords: Strategic Change; Biosimilars; Medical Biotechnology; Emerging Markets; Industry Structure; Uncertainty; Strategy Development; Implementation; Corporate Strategy; Pharmaceutical Industry; Pharmaceutical Industry; United States

August 1994
Teaching Note

Nippon Kayaku TN

By: Robin Cooper and Robert S. Kaplan

Keywords: Pharmaceutical Industry; Pharmaceutical Industry; Tokyo

May 2013 (Revised October 2014)
Case

Novartis: Leading a Global Enterprise

By: William W. George, Krishna G. Palepu and Carin-Isabel Knoop

Novartis, the world's leading healthcare company, was formed in 1996 out of a merger of two very different, mid-tier Switzerland-based pharma companies. The case traces the company's evolution over the past 17 years, as it transformed into a truly global enterprise... View Details

Keywords: Multinational Firms and Management; Talent and Talent Management; Organizational Structure; Organizational Culture; Success; Globalized Markets and Industries; Management Teams; Change Management; Business History; Mergers and Acquisitions; Global Strategy; Health Care and Treatment; Pharmaceutical Industry; Pharmaceutical Industry; Switzerland

February 2010 (Revised April 2010)
Case

Organization and Strategy at Millennium (A)

By: Julie M. Wulf and Scott Waggoner

This case examines Millennium's strategic and organizational responses to the rapid evolution of the biopharmaceutical industry. In the early 2000s, as Millennium's competitive advantage in early-stage research slipped away and its losses mounted, founder and CEO Mark... View Details

Keywords: Transformation; Leading Change; Management Succession; Organizational Change and Adaptation; Competitive Strategy; Competitive Advantage; Pharmaceutical Industry; Pharmaceutical Industry

January 2009
Teaching Note

Biocon: Launching a New Cancer Drug in India (TN)

By: Sunil Gupta and Das Narayandas

Teaching Note for [508026]. View Details

Keywords: Product Launch; Market Timing; Price; Distribution Channels; Marketing Strategy; Health Care and Treatment; Pharmaceutical Industry; Pharmaceutical Industry; India

August 2007 (Revised November 2008)
Case

Biocon: Launching a New Cancer Drug in India

By: Sunil Gupta and Das Narayandas

Kiran Majumdar-Shaw, the CEO of Biocon has to make product launch timing, pricing, channel, and communications mix decisions relating to the launch of BioMAb, a new cancer drug in India. View Details

Keywords: Price; Health Care and Treatment; Marketing Strategy; Product Launch; Planning; Pharmaceutical Industry; Pharmaceutical Industry; India

March 2006
Teaching Note

Stan Lapidus: Profile of a Medical Entrepreneur (TN)

By: Robert F. Higgins, Richard G. Hamermesh and Erin Seefeld

Teaching Note to (805-087). View Details

Keywords: Personal Development and Career; Entrepreneurship; Business Startups; Pharmaceutical Industry; Pharmaceutical Industry

April 2003 (Revised October 2004)
Case

Novartis: The Challenge of Success (B)

By: Sandra J. Sucher and Stacy McManus

When Dr. Daniel Vasella learned of the early Phase 1 trial results, he immediately decided what course of action Novartis would take. Students will be able to examine and assess the concrete steps, and the rationale behind them, that Novartis took in response to this... View Details

Keywords: Decision Making; Moral Sensibility; Innovation and Invention; Distribution; Product Development; Production; Problems and Challenges; Research and Development; Pharmaceutical Industry; Pharmaceutical Industry

April 2003 (Revised October 2004)
Case

Novartis: The Challenge of Success (A)

By: Sandra J. Sucher and Stacy McManus

Preliminary results from Phase 1 clinical trials of a newly developed compound, STI571, showed that 31 out of 31 patients with chronic myelogenous leukemia (CML) had their blood counts return to normal. In the world of oncology, this was unheard of. This was the... View Details

Keywords: Decision Making; Health Testing and Trials; Innovation and Invention; Markets; Distribution; Product Development; Production; Problems and Challenges; Research; Research and Development; Complexity; Pharmaceutical Industry; Pharmaceutical Industry

December 2002
Teaching Note

Abgenix and the XenoMouse (TN)

By: John T. Gourville

Teaching Note for (501-061). View Details

Keywords: Health Testing and Trials; Decision Choices and Conditions; Sales; Product Development; Joint Ventures; Pharmaceutical Industry; Pharmaceutical Industry

May 2002 (Revised December 2003)
Teaching Note

Medicines Company, The TN

By: John T. Gourville

Teaching Note for (9-502-006). View Details

Keywords: Pharmaceutical Industry; Pharmaceutical Industry

August 2001 (Revised March 2008)
Case

Helios Health (A)

By: Regina E. Herzlinger and Alfred Martin

Helios PC system provides personalized drug information to the patients in the doctor's waiting room. It has met with considerable consumer acceptance and a very high return for the drug companies that sponsor it. What price should it charge them for the service? View Details

Keywords: Entrepreneurship; Price; Health Care and Treatment; Information Publishing; Innovation and Invention; Product Marketing; Demand and Consumers; Pharmaceutical Industry; Pharmaceutical Industry

Find at Harvard

March 1995 (Revised January 1996)
Teaching Note

Portfolio Planning at Ciba-Geigy and the Newport Investment Proposal TN

By: David J. Collis

Teaching Note for (9-795-040). View Details

Keywords: Pharmaceutical Industry; Pharmaceutical Industry; Switzerland

2007
Chapter

Fighting AIDS, Fighting Poverty: Customer Centric Marketing in the Generic Antiretroviral Business

By: Rohit Deshpandé and Zoe Chance

Keywords: Health Disorders; Poverty; Product Marketing; Customers; Pharmaceutical Industry; Pharmaceutical Industry

September 1990 (Revised March 1991)
Supplement

RU 486 (B)

By: Joseph L. Badaracco Jr.

Describes how Roussel UCLAF resolved the dilemma. Intended for use as an in-class handout. View Details

Keywords: Pharmaceutical Industry; Pharmaceutical Industry; France; Germany; United States

09 Jan 2007
First Look

First Look: January 9, 2007

http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=707413 Teva Pharmaceutical Industries, Ltd. Harvard Business School Case 707-441 Purchase this case: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=707441 ... View Details

Keywords: Martha Lagace

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