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  • February 2015 (Revised November 2015)
  • Supplement

Building an Integrated Biopharma Company: Crucell (B)

By: Richard G. Hamermesh, Marianne Van Der Steen and Susan Harmeling
The Crucell (B) case updates events at Crucell since 2009. In September, 2009, Johnson & Johnson acquired 18% of Crucell for $400 million. This investment was part of a business development deal. Subsequently, in 2012, Johnson & Johnson acquired Crucell for $2.8... View Details
Keywords: Biotechnology; Biopharmacy Company; Licensing Agreements In Biopharmacy; Licensing; Human Cell-line Technology; Vaccine; Healthcare Innovation; Global Health; Entrepreneurship; Health Care and Treatment; Acquisition; Innovation and Invention; Biotechnology Industry; Pharmaceutical Industry
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Hamermesh, Richard G., Marianne Van Der Steen, and Susan Harmeling. "Building an Integrated Biopharma Company: Crucell (B)." Harvard Business School Supplement 815-086, February 2015. (Revised November 2015.)
  • April 2020 (Revised October 2021)
  • Case

SpaceX, Economies of Scale, and a Revolution in Space Access

By: Matthew C. Weinzierl, Kylie Lucas and Mehak Sarang
From the time he transformed the world of online banking, Elon Musk established himself as a bold innovator. After selling X.com to PayPal in 2002, he founded a series of revolutionary start-ups, starting with Space Exploration Technologies (SpaceX). Hoping to "make... View Details
Keywords: Space Tech; Space Access; Vision; Economies Of Scale; Technological Innovation; Emerging Markets; Commercialization; Finance; Aerospace Industry
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Weinzierl, Matthew C., Kylie Lucas, and Mehak Sarang. "SpaceX, Economies of Scale, and a Revolution in Space Access." Harvard Business School Case 720-027, April 2020. (Revised October 2021.)
  • June 2016
  • Case

Aggressive Growth Plans For Zimmer Spine

By: Kevin Schulman and Miranda Shaw
Steve Healy, the President of Zimmer Spine, has to transform his organization into a market leader. Zimmer is a major medical device firm, but the Spine division has underperformed, and its core technology did not get the expanded FDA label that had been expected. The... View Details
Keywords: Medical Device; Organizational Innovation; Organizational Growth; Organizations; Growth and Development Strategy; Medical Devices and Supplies Industry
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Schulman, Kevin, and Miranda Shaw. "Aggressive Growth Plans For Zimmer Spine." Harvard Business School Case 316-106, June 2016.
  • February 2022
  • Case

Cleveland Clinic Abu Dhabi (Abridged)

By: Linda A. Hill and Emily Tedards
In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By... View Details
Keywords: Organization Behavior; Culture; Alignment; Organizational Effectiveness; Purpose; Impact; Leadership Development; Diversity; Collaboration; Co-creation; Learning Organizations; Empowerment; Teams; Team Dynamics; Teamwork; Team Effectiveness; Trust; Talent; Talent Development And Retention; Psychological Safety; Organizational Evolution; Coaching; Board; Analytics; Innovation; Data; Data Visualization; Digital Technology; Digital; Customer Experience; Experimentation; Change Management; Data-driven Decision-making; Debates; Ecosystem; Partnership; Telemedicine; Sustainability; Global Organizations; Local; Hospital; Healthcare; United Arab Emirates; Health Care and Treatment; Partners and Partnerships; Globalization; Quality; Organizational Culture; Mission and Purpose; Innovation and Management; Information Technology; Joint Ventures; Leadership; Performance Effectiveness; Abu Dhabi; United Arab Emirates
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Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi (Abridged)." Harvard Business School Case 422-056, February 2022.
  • 28 Aug 2018
  • First Look

New Research and Ideas, August 28, 2018

Cai, Wei, Susanna Gallani, and Jee-Eun Shin Abstract— Organizations often struggle with motivating employees to develop innovative ideas that may benefit the firm, especially when the standard tasks for... View Details
Keywords: Dina Gerdeman
  • 07 Nov 2019
  • News

The Future Of Education In Family Business Leadership And Tips To Get Started

  • 14 May 2014
  • News

(Re)moving the Needle

injector, which uses a "liquid needle" only 100 micrometers in diameter, delivers drugs through the skin at any location, at any desired depth and volume. "We believe our patented technology will transform... View Details
Keywords: Robert S. Benchley; medical technology; Scientific Research and Development Services
  • 23 Oct 2019
  • News

Hands-on Simulations Complement the Case Method

participate in two simulations in the required Technology and Operations Management (TOM) course. The “Shad Exercise” provides a sense of the challenges of managing a complex process. In teams of 12,... View Details
Keywords: Educational Innovation
  • January 2016 (Revised March 2016)
  • Case

Whither the Weather (Company): Forecasting 2016

By: Rosabeth Moss Kanter and Jonathan Cohen
CEO David Kenny led the transformation of the Weather Company from a television business to a Big Data technology company from 2012 until 2016, when IBM acquired its digital assets. This case discusses major decisions taken by Kenny starting in 2014 as he sought to... View Details
Keywords: Weather Company; IBM; Digital; Technology; David Kenny; Television; Weather Channel; Legacy Business; Mainstream; Newstream; Reorganization; Acquisitions; Transformation; Information Technology; Television Entertainment; Acquisition; Consolidation; Change; Leadership
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Kanter, Rosabeth Moss, and Jonathan Cohen. "Whither the Weather (Company): Forecasting 2016." Harvard Business School Case 316-143, January 2016. (Revised March 2016.)
  • February 2015 (Revised November 2015)
  • Case

Building an Integrated Biopharma Company: Crucell (A)

By: Richard G. Hamermesh, Marianne Van Der Steen and Susan S. Harmeling
By 2009, Crucell had become the largest biopharma company in the Netherlands and a symbol of national pride. The case traces the evolution of the company from a University spin-off into a fully-integrated company. Crucell's success, particularly in the vaccine space,... View Details
Keywords: Biotechnology; Biopharmacy Company; Licensing; Licensing Agreements In Biopharmacy; Human Cell-line Technology; Vaccine; Healthcare Innovation; Global Health; Partners and Partnerships; Entrepreneurship; Growth and Development Strategy; Biotechnology Industry; Pharmaceutical Industry; Netherlands
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Hamermesh, Richard G., Marianne Van Der Steen, and Susan S. Harmeling. "Building an Integrated Biopharma Company: Crucell (A)." Harvard Business School Case 815-085, February 2015. (Revised November 2015.)
  • March 2021
  • Teaching Plan

The Black New Venture Competition

By: Karen G. Mills, Jeffrey J. Bussgang, Martin A. Sinozich and Gabriella Elanbeck
Black entrepreneurs encounter many unique obstacles when raising capital to start and grow a business, some stemming from deep systemic discrimination. During their second year at Harvard Business School (HBS), MBA students Kimberly Foster and Tyler Simpson decided to... View Details
Keywords: Analytics; Startup; Start-up; Startup Financing; Financing; Startups; Start-ups; Business And Community; Business And Society; Business Growth; Discrimination; Women; Women-owned Businesses; African Americans; African-american Entrepreneurs; African-american Investors; African-American Protagonist; African-American Women; Early Stage Funding; Early Stage; Innovation & Entrepreneurship; Innovation Competitions; Entrepreneurial Financing; Business Plan; Business Startups; Diversity; Gender; Race; Entrepreneurship; Venture Capital; Small Business; Leadership; Information Technology; Competition
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Mills, Karen G., Jeffrey J. Bussgang, Martin A. Sinozich, and Gabriella Elanbeck. "The Black New Venture Competition." Harvard Business School Teaching Plan 821-094, March 2021.
  • September 2023
  • Background Note

Amager Bakke: Municipal Waste to Energy

By: Willy Shih, Michael W. Toffel and Kelsey Carter
This background note describes the Amager Bakke waste-to-energy (WtE) plant in Copenhagen, which merges traditional waste incineration with a combined heat and power (CHP) plant and air pollution control (scrubbing) technology, and had plans to add carbon dioxide (CO2)... View Details
Keywords: Decarbonization; Innovation; Innovation Focused Strategy; Environmental Operations; Circular; Waste Heat Recovery; Waste Management; Carbon Regulation; Buildings and Facilities; Energy Generation; Environmental Sustainability; Pollution; Climate Change; Wastes and Waste Processing; Innovation Leadership; Innovation Strategy; Energy Industry; Denmark; Netherlands; Europe; European Union
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Shih, Willy, Michael W. Toffel, and Kelsey Carter. "Amager Bakke: Municipal Waste to Energy." Harvard Business School Background Note 624-040, September 2023.
  • March 2008 (Revised December 2011)
  • Case

IBM Values and Corporate Citizenship

By: Rosabeth M. Kanter
IBM's transformation into a globally integrated enterprise (GIE) began with a conviction about what should never change. Since its founding in 1911, the company operated under a set of principles articulated by founder Thomas Watson and became known for a strong... View Details
Keywords: Values and Beliefs; Globalized Firms and Management; Technological Innovation; Leading Change; Corporate Social Responsibility and Impact; Organizational Change and Adaptation; Organizational Culture; Integration
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Kanter, Rosabeth M. "IBM Values and Corporate Citizenship." Harvard Business School Case 308-106, March 2008. (Revised December 2011.)
  • 07 Sep 2021
  • News

Focus on Health and Equity to Meet 2026 Climate Goal, Advises Sustainability Committee

  • November 2018 (Revised January 2022)
  • Case

JUUL and the Vaping Revolution

By: Michael W. Toffel, John Masko and Sarah Mehta
In late 2019, San Francisco-based electronic cigarette (e-cigarette) maker JUUL Labs (pronounced “jewel”) faced intense pressure. Sales of JUUL products exceeded $1 billion in 2018, dominating the e-cigarette category. While JUUL Labs’ stated goal was to help current... View Details
Keywords: Electronic Cigarettes; E-Cigarettes; Vaping; Nicotine Replacement; JUUL; Juuling; Advertising; Digital Marketing; Customers; Innovation and Invention; Marketing; Ethics; Brands and Branding; Marketing Communications; Marketing Strategy; Product Marketing; Corporate Social Responsibility and Impact; Social Issues; Information Technology; Technology Industry; San Francisco; California
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Toffel, Michael W., John Masko, and Sarah Mehta. "JUUL and the Vaping Revolution." Harvard Business School Case 619-006, November 2018. (Revised January 2022.)
  • 02 Apr 2019
  • First Look

New Research and Ideas, April 2, 2019

Frame Flexibility: The Role of Cognitive and Emotional Framing in Innovation Adoption by Incumbent Firms By: Raffaelli, Ryan, Mary Ann Glynn, and Michael Tushman Abstract—Why... View Details
Keywords: Dina Gerdeman
  • June 2016 (Revised August 2019)
  • Case

Numenta: Inventing and (or) Commercializing AI

By: David B. Yoffie, Liz Kind and David Ben Shimol
In March 2016, Donna Dubinsky (co-founder and CEO) and Jeff Hawkins (co-founder) were struggling with a key question: Could Numenta be successful in both creating fundamental technology and building a commercial business? Located in Redwood City, CA, Numenta was... View Details
Keywords: Artificial Intelligence; Machine Intelligence; Machine Learning; Strategy; Business Model; Entrepreneurship; Information; Technological Innovation; Research; Research and Development; Information Technology; Applications and Software; Technology Adoption; Digital Platforms; Commercialization; AI and Machine Learning
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Yoffie, David B., Liz Kind, and David Ben Shimol. "Numenta: Inventing and (or) Commercializing AI." Harvard Business School Case 716-469, June 2016. (Revised August 2019.)
  • January 2017 (Revised December 2017)
  • Case

Carmichael Roberts: To Create a Private Equity Firm?

By: Steven Rogers and Kenneth J. Cooper
Carmichael Roberts, a rare African-American venture capitalist, considered leaving his general partnership in a private equity firm near Boston and setting up his own in 2015. He weighed whether the timing was right, with the economy still not fully recovered from the... View Details
Keywords: Venture Capital; Equity; Innovation And Invention; Investment; Ownership; Science; Science Bassed Business; Markets; Relationships; Capital; Private Equity; Technological Innovation; Investment Return; Going Public; Ownership Stake; Science-Based Business; Market Timing; Marketplace Matching; Partners and Partnerships; Technology Industry; Technology Industry; Technology Industry; United States; Massachusetts; Boston; California; San Francisco; New York (city, NY)
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Rogers, Steven, and Kenneth J. Cooper. "Carmichael Roberts: To Create a Private Equity Firm?" Harvard Business School Case 317-079, January 2017. (Revised December 2017.)
  • June 2011
  • Supplement

Q and A Sessions with Akhil Gupta, Deputy Group CEO and Managing Director of Bharti Enterprises

This tape includes the highlights of question and answer sessions with Akhil Gupta, Deputy Group CEO and Managing Director of Bharti Enterprises, one of the largest mobile phone companies in India. The video focuses on the challenges and lessons learned from Bharti's... View Details
Keywords: Management; Mobile and Wireless Technology; Job Cuts and Outsourcing; Agreements and Arrangements; Innovation and Invention; Telecommunications Industry; India
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Martinez Jerez, F. Asis, and Lisa Brem. "Q and A Sessions with Akhil Gupta, Deputy Group CEO and Managing Director of Bharti Enterprises." Harvard Business School Video Supplement 111-710, June 2011.
  • 18 Dec 2018
  • First Look

New Research and Ideas, December 18, 2018

2018 Innovation Policy and the Economy The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century By: Bagley, Nicholas, Benjamin Berger, Amitabh... View Details
Keywords: Dina Gerdeman
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