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September 20, 2024
Article

It’s Time to Unbundle ESG

By: Aaron K. Chatterji and Michael W. Toffel

ESG is at an inflection point. It has come to represent a broad and inchoate aspiration for what business should be doing beyond maximizing shareholder value. With ESG advocates on the defensive, business leaders need a new roadmap to determine which factors to... View Details

Keywords: ESG; ESG (Environmental, Social, Governance) Performance; ESG Ratings; ESG Reporting; ESG Disclosure; Sustainability; Climate; Climate Finance; Climate Risk; Social Accounting; Investment; Governance; Safety; Climate Change; Environmental Sustainability; Corporate Social Responsibility and Impact; Financial Services Industry

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September 2024
Exercise

Assessing the Value of Unifying and De-Duplicating Customer Data

By: Elie Ofek and Hema Yoganarasimhan

This exercise provides an opportunity for students to gain hands on experience with assessing the value of unifying various customer databases that a firm may have (e.g., across the different brands it markets) and of properly identifying customers to avoid duplication... View Details

Keywords: Customer Relationship Management; Measurement and Metrics; Analytics and Data Science; Value

September 2024
Case

Myeloma Investment Fund

By: Kyle Myers and Scott Sawaya

This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.

The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details

Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation ＆ Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry

September 9, 2024
Article

Ten Questions for a Winning Climate-transition Business Strategy

By: George Serafeim

The move to a low-carbon economy will create opportunities for innovation and growth. To make the most of them, leaders must understand the challenges they could face along the way. View Details

Keywords: Technology; Organizational Transformations; Business Model Innovation; Innovation and Invention; Climate Change; Transformation; Leadership; Business Strategy; Environmental Sustainability; Change Management; Entrepreneurship

2024
Working Paper

Empirical Guidance: Data Processing and Analysis with Applications in Stata, R, and Python

By: Melissa Ouellet and Michael W. Toffel

This paper describes a range of best practices to compile and analyze datasets, and includes some examples in Stata, R, and Python. It is meant to serve as a reference for those getting started in econometrics, and especially those seeking to conduct data analyses in... View Details

Keywords: Empirical Methods; Empirical Operations; Statistical Methods And Machine Learning; Statistical Interferences; Research Analysts; Analytics and Data Science; Mathematical Methods

September 2024
Article

Standing on the Shoulders of Science

By: Joshua Lev Krieger, Monika Schnitzer and Martin Watzinger

Today’s innovations rely on scientific discoveries of the past, yet only some corporate R&D builds directly on scientific output. In this paper, we analyze U.S. patents to investigate how firms generate value by building on prior art “closer” to science. We show... View Details

Keywords: Patent Novelty; Value Capture; Science; Patents; Valuation; Research and Development

September–October 2024
Article

Where Data-Driven Decision-Making Can Go Wrong

By: Michael Luca and Amy C. Edmondson

When considering internal data or the results of a study, often business leaders either take the evidence presented as gospel or dismiss it altogether. Both approaches are misguided. What leaders need to do instead is conduct rigorous discussions that assess any... View Details

Keywords: Information; Analytics and Data Science; Analysis; Decision Making

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August 2024
Background Note

The Five Pillars That Drive the Success or Failure of Healthcare and Life Sciences Innovations

By: Regina E. Herzlinger

2024
Case

EPCorp: What Story Does the Data Tell?

By: Jacob M. Cook

In EPCorp: What Story Does the Data Tell?, the Quick Case begins with Shivani Bahl researching problems with her company's website so that she can begin to analyze which option would help EPCorp most: selling all its products on Amazon or improving its own data... View Details

Keywords: Distribution Channels; E-commerce; Analytics and Data Science; Decision Making

August 2024
Case

Iogen: Decarbonizing Hard-to-Abate Sectors

By: George Serafeim, Charlotte Foody and John Mulliken

Brian Foody, CEO of Iogen Corporation, was an early leader in advanced biofuels, developing a range of technologies to transform agricultural waste into transportation fuel. With $100 million in revenue and 350 patents across various biofuel technologies, Iogen was... View Details

Keywords: Technology; Biofuel; Market Attractiveness; Decarbonization; Technological Innovation; Climate Change; Energy; Environmental Sustainability; Transformation; Market Entry and Exit; Strategy; Energy Industry; United States; United Kingdom

August 2024
Technical Note

Introduction to Data Analysis in Python

By: Michael Parzen and Jo Ellery

This note introduces Python as a tool for data science, including the Pandas library for data analysis. View Details

Keywords: Analytics and Data Science

August 2024
Course Overview Note

Entrepreneurship in the Life Sciences Fall Term 2024: Course Outline and Syllabus

By: Satish Tadikonda and William Marks

August 2024
Course Overview Note

Field Course: Life Sciences Venture Creation Fall Term 2024 - Course Outline and Syllabus

By: Satish Tadikonda and William Marks

August 2024 (Revised November 2024)
Case

Commonwealth Fusion Systems: Born at Scale

By: Joshua Lev Krieger, Jim Matheson, Kyle Myers, Gunnar Trumbull and Richard Vietor

This case study chronicles the journey of Commonwealth Fusion Systems (CFS) on its ambitious mission to commercialize fusion energy and become the world’s leading provider of fusion power plants. Emerging from a “special arrangement” with MIT's Plasma Science and... View Details

Keywords: Nuclear Energy; Innovation; Entrepreneurship; Entrepreneurial Finance; Energy Generation; Commercialization; Science-Based Business; Technological Innovation; Market Entry and Exit; Energy Industry

2024
Book

Fintech, Small Business & the American Dream: How Technology Is Transforming Lending and Shaping a New Era of Small Business Opportunity

By: Karen G. Mills

The second edition of Fintech, Small Business & the American Dream, builds on the groundbreaking 2019 book with new insights on how technology and artificial intelligence are transforming small business lending. This ambitious view covers the significance of... View Details

Keywords: Fintech; AI; AI and Machine Learning; Small Business; Economy; Technology Adoption; Credit; Financing and Loans; Analytics and Data Science

July 2024
Technical Note

Introduction to SQL in Python

By: Michael Parzen and Jo Ellery

This note walks through the basics of SQL and how to use this language in Python via the SQLite package. View Details

Keywords: Analytics and Data Science

July 2024
Case

ZEISS: Commercializing Science

By: Maria P. Roche, Carlota Moniz and Daniela Beyersdorfer

Karl Lamprecht, President and CEO of the ZEISS AG Group, mused on how far ZEISS had come in 175 years of being a pioneer in optics, and how the course he had charted since taking the helm of the company could keep it on track. In his role, he oversaw the four core... View Details

July–August 2024
Article

Disclosing Downstream Emissions

By: Robert S. Kaplan and Karthik Ramanna

An increasing number of companies are using the E-liability carbon-accounting method as an important tool for tracking progress toward reducing global emissions in their supply chains. The system does not require formal accounting for downstream emissions—those... View Details

Keywords: Carbon Emissions; Environmental Accounting; Corporate Accountability; Corporate Social Responsibility and Impact; Corporate Disclosure; Environmental Sustainability

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July 2024
Article

How Artificial Intelligence Constrains Human Experience

By: A. Valenzuela, S. Puntoni, D. Hoffman, N. Castelo, J. De Freitas, B. Dietvorst, C. Hildebrand, Y.E. Huh, R. Meyer, M. Sweeney, S. Talaifar, G. Tomaino and K. Wertenbroch

Many consumption decisions and experiences are digitally mediated. As a consequence, consumer behavior is increasingly the joint product of human psychology and ubiquitous algorithms (Braun et al. 2024; cf. Melumad et al. 2020). The coming of age of Large Language... View Details

Keywords: Large Language Model; User Experience; AI and Machine Learning; Consumer Behavior; Technology Adoption; Risk and Uncertainty; Cost vs Benefits

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June 2024
Simulation

Vehicle Lifecycle Emissions Calculator

By: Mike Toffel, Shirley Lu and George Serafeim

This Vehicle Lifecycle Emissions Calculator calculates the greenhouse gas emissions over the lifespan of internal combustion engine (ICEs) vehicles, battery electric vehicles (BEVs), and plug-in hybrid electric vehicles (PHEV), including those associated with their... View Details

Keywords: Decarbonization; Environment; Carbon Accounting; Carbon; Carbon Abatement; Electric Vehicles; Automobiles; Environmental Accounting; Environmental Management; Environmental Sustainability; Strategy; Technological Innovation; Supply Chain; Business and Stakeholder Relations; Climate Change; Transportation; Transportation Industry; Auto Industry; Battery Industry

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