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2024
Working Paper

Prozac—Controversial Blockbuster: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes the development of Prozac, a blockbuster drug that transformed the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we chronicle the: 1) prior treatments for depression and the research that... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins

We describe the development of tamoxifen, considered a “gold standard” treatment for millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s development; the initial development of tamoxifen from 1960 to 1973;... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation and Invention; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Governing Rules, Regulations, and Reforms

June 2020
Case

Breakthroughs at Blueprint Medicines

By: Richard G. Hamermesh, Kathy Giusti and Susie L. Ma

Precision medicine company Blueprint Medicines was building a successful track record for bringing drug therapies to market 40% faster than average. The company had spent $40 million dollars and two years building a compound library that became its drug development... View Details

Keywords: Precision Medicine; Cancer; Biotechnology; Drug Development; Strategy; Expansion; Science; Genetics; Information Technology; Entrepreneurship; Organizational Culture; Management; Growth and Development; Pharmaceutical Industry; United States; Cambridge; Massachusetts

June 2020 (Revised January 2023)
Case

Shinola Detroit: Optimizing Product Line Breadth

By: Robert J. Dolan

June 2020
Teaching Note

Shiseido Acquires Drunk Elephant

On October 7, 2019, the Shiseido Group announced that it would acquire clean skincare brand Drunk Elephant for $845 million, a valuation of 8.5 times sales. Did Shiseido pay too much or too little for this brand asset? How much was the Drunk Elephant brand worth and... View Details

June 2020 (Revised January 2024)
Case

TraceTogether

By: Mitchell B. Weiss and Sarah Mehta

By April 7, 2020, over 1.4 million people worldwide had contracted the novel coronavirus (COVID-19). Governments raced to curb the spread of COVID-19 by scaling up testing, quarantining those infected, and tracing their possible contacts. It had taken Singapore’s... View Details

Keywords: COVID-19; Contact Tracing; Government Administration; Crisis Management; Health; Health Pandemics; Innovation and Invention; Innovation Leadership; Innovation Strategy; Technological Innovation; Social Issues; Information Technology; Mobile and Wireless Technology; Applications and Software; Technology Adoption; Health Industry; Public Administration Industry; Singapore

June 2020
Supplement

Moleskine (B): Maria Sebregondi and Arrigo Berni Video Supplements

By: Ryan Raffaelli and Raffaella Sadun

June 2020
Supplement

Sanjeev Kapoor (A) Video Supplements

By: Boris Groysberg

June 2020
Supplement

Sanjeev Kapoor (B) Video Supplements

By: Boris Groysberg

2020
Other Teaching and Training Material

Leading the Charge: A Podcase about Product Management at Opower

By: Jeffrey Rayport and John J. Lafkas

The Opower podcase materials contain audio from professor Jeffrey Rayport's interview with Ben Foster, the former vice president of product management at Opower, and more recently the co-founder of Prodify. In the podcase, Ben discusses how product management works in... View Details

Keywords: Product; Management; Growth and Development Strategy; Customization and Personalization; Conflict Management; Software

June 2020
Case

Recovering Trust After Corporate Misconduct at Wells Fargo

By: Suraj Srinivasan and Jonah S. Goldberg

The case describes widespread misconduct at Wells Fargo Community Bank in the period leading up to 2017 and the company’s subsequent attempts to improve internal controls, company culture, and corporate governance. The case examines the potential causes of large scale... View Details

Keywords: Corporate Misconduct; Internal Controls; Banks and Banking; Crime and Corruption; Corporate Governance; Organizational Culture; Governance Compliance; Management Systems; Organizational Change and Adaptation; Performance Improvement; Governing and Advisory Boards

June 2020 (Revised August 2020)
Case

Majid Al Futtaim Retail Geographic Expansion: Brick or Click?

By: Juan Alcácer and Alpana Thapar

This case illustrates the challenges that retailers face when they aggressively pursue geographical growth by expanding both their physical store network and their online presence. It features Majid Al Futtaim (MAF) Retail, a franchisee of Carrefour hypermarkets in the... View Details

Keywords: Stores; Ecommerce; Strategy; Expansion; Geographic Location; Decision Making; Internet and the Web; Digital Transformation; E-commerce; Retail Industry; Middle East

2021
Working Paper

Two Case Studies on the Financing of Forest Conservation

By: Andrew Baxter, Connor Cash, Josh Lerner and Ratnika Prasad

A variety of factors is leading to fresh approaches to the ownership and management of forestland, with an emphasis on the combination of conservation goals and private investments. But the barriers to successfully achieving attractive financial returns and desirable... View Details

Keywords: Financing; Forestry; Environmental Management; Natural Resources; Financing and Loans

June 24, 2020
Article

Wolfgang Puck on Leading His Restaurants Through the Pandemic

By: Boris Groysberg

Chef Wolfgang Puck shares his experience leading his restaurants and other businesses through the pandemic crisis. He explains how his company has pivoted to find new sources of revenue and how he has become a vocal advocate for the restaurant industry. He also... View Details

Keywords: Coronavirus Pandemic; Restaurants; Restaurant Industry; Reopening; Health Pandemics; Crisis Management; Organizational Change and Adaptation; Safety

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June 2020 (Revised April 2022)
Case

AFC Ajax

By: Anita Elberse

In July 2019, AFC Ajax’s chief executive officer Edwin van der Sar finalized one of the biggest transfers in soccer—that of Matthijs de Ligt, only 19 years old but already one of the sports world’s brightest stars—from AFC Ajax to Italian powerhouse Juventus FC for a... View Details

Keywords: Soccer; Talent and Talent Management; Sports; Globalization; Competitive Advantage; Strategy; Sports Industry; Europe

June 2020
Supplement

TransDigm in 2017: Congressional Hearing on the DoD Inspector General’s Report (5/15/19)

By: Benjamin C. Esty

This video accompanies the case, “TransDigm in 2017: The Beginning of the End or the End of the Beginning?” View Details

June 2020
Teaching Plan

Chief

By: Katherine B. Coffman, Jeffrey J. Bussgang, Kathleen L. McGinn, Julia Kelley, Amy Klopfenstein and Katherine Chen

Teaching Plan serves as a supplement to the case for “Chief: Role for Carolyn Childers” (920-019), “Chief: Role for Lindsay Kaplan” (920-020), and “Scaling at Chief” (920-021). View Details

June 2020
Teaching Note

Sony

By: Stefan H. Thomke

Teaching Note for HBS Case No. 618-045. View Details

June 2020
Supplement

TransDigm: The Acquisition of Aerosonic Corp.

By: Benjamin C. Esty and Daniel W. Fisher

This courseware accompanies the case "TransDigm: The Acquisition of Aerosonic Corp." View Details

Keywords: Mergers and Acquisitions; Growth Management; Business Strategy; Competitive Strategy; Value Creation; Valuation; Negotiation; Cash Flow; Contracts; Aerospace Industry; Air Transportation Industry; United States

June 2020
Case

TransDigm: The Acquisition of Aerosonic Corp.

By: Benjamin C. Esty and Daniel W. Fisher

In April 2013, TransDigm, a company that manufactured a wide range of highly engineered aerospace parts for both military and commercial aircraft, announced an agreement to acquire Aerosonic Corporation for $39 million in cash (1.2 times Aerosonic’s sales of $31... View Details

Keywords: Mergers and Acquisitions; Growth Management; Business Strategy; Competitive Strategy; Value Creation; Valuation; Negotiation; Cash Flow; Contracts; Aerospace Industry; Air Transportation Industry; United States

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