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      • November 2009 (Revised March 2010)
      • Case

      Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story

      By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon
      In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had... View Details
      Keywords: Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Marketing Strategy; Product Positioning; Genetics; Biotechnology Industry; Europe; United States
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      Hamermesh, Richard G., Raju Kucherlapati, and Rachel Gordon. "Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story." Harvard Business School Case 810-066, November 2009. (Revised March 2010.)
      • October 2009 (Revised June 2010)
      • Case

      Hulu: An Evil Plot to Destroy the World?

      By: Anita Elberse and Sunil Gupta
      In July 2009, Jason Kilar, the chief executive officer of Hulu, is debating whether the online video aggregator should move away from a purely advertising-supported model, and whether it should participate in an industry-wide initiative to develop and test... View Details
      Keywords: Advertising; Business Model; Television Entertainment; Distribution Channels; Service Operations; Internet and the Web; Media and Broadcasting Industry; Motion Pictures and Video Industry
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      Elberse, Anita, and Sunil Gupta. "Hulu: An Evil Plot to Destroy the World?" Harvard Business School Case 510-005, October 2009. (Revised June 2010.)
      • 2009
      • Working Paper

      Operational Failures and Problem Solving: An Empirical Study of Incident Reporting

      By: Julia Rose Adler-Milstein, Sara J. Singer and Michael W. Toffel
      Operational failures occur in all industries with consequences that range from minor inconveniences to major catastrophes. Many organizations have implemented incident reporting systems to highlight actual and potential operational failures in order to encourage... View Details
      Keywords: Communication Strategy; Legal Liability; Management Practices and Processes; Service Operations; Failure; Health Industry
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      Adler-Milstein, Julia Rose, Sara J. Singer, and Michael W. Toffel. "Operational Failures and Problem Solving: An Empirical Study of Incident Reporting." Harvard Business School Working Paper, No. 10-017, September 2009. (August 2009.)
      • July 2009
      • Teaching Note

      The Miami Project to Cure Paralysis (TN)

      By: Robert Steven Kaplan, Christopher Marquis and Ben Creo
      Teaching Note for [408003]. View Details
      Keywords: Nonprofit Organizations; Research; Health Care and Treatment; Medical Specialties; Financing and Loans; Leadership; Strategy; Problems and Challenges; Health Testing and Trials; Miami
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      Kaplan, Robert Steven, Christopher Marquis, and Ben Creo. "The Miami Project to Cure Paralysis (TN)." Harvard Business School Teaching Note 410-005, July 2009.
      • 2009
      • Working Paper

      Culture Clash: The Costs and Benefits of Homogeneity

      By: Eric J. Van den Steen
      This paper develops an economic theory of the costs and benefits of corporate culture—in the sense of shared beliefs and values—in order to study the effects of "culture clash" in mergers and acquisitions. I first use a simple analytical framework to show that shared... View Details
      Keywords: Mergers and Acquisitions; Cost vs Benefits; Values and Beliefs; Organizational Change and Adaptation; Organizational Culture; Motivation and Incentives; Theory
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      Van den Steen, Eric J. "Culture Clash: The Costs and Benefits of Homogeneity." Harvard Business School Working Paper, No. 10-003, July 2009.
      • April 2009 (Revised June 2010)
      • Case

      Supply Chain Partners: Virginia Mason and Owens & Minor (A)

      By: V.G. Narayanan and Lisa Brem
      Virginia Mason Medical Center (VM) hired Owens & Minor (O&M) as its alpha vendor for medical/surgical supplies in 2004. By 2005, O&M was performing Just-in-Time and Low Unit of Measure services for VM, but they believed the pricing model in the industry was outdated.... View Details
      Keywords: Activity Based Costing and Management; Price; Distribution; Supply Chain Management; Medical Devices and Supplies Industry
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      Narayanan, V.G., and Lisa Brem. "Supply Chain Partners: Virginia Mason and Owens & Minor (A)." Harvard Business School Case 109-076, April 2009. (Revised June 2010.)
      • April 2009 (Revised August 2009)
      • Case

      Backchannelmedia: Making Television 'Clickable'

      By: Sunil Gupta, Kavita Shukla and Zachary Scott Clayton
      Backchannelmedia (BCM), a three-year-old start-up, intended to completely disrupt the world of advertising by transforming the way Americans watched television. BCM had developed a technology to make television "clickable," enabling viewers to interact with the content... View Details
      Keywords: Entrepreneurship; Investment; Disruptive Innovation; Technological Innovation; Marketing Strategy; Partners and Partnerships; Competition
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      Gupta, Sunil, Kavita Shukla, and Zachary Scott Clayton. "Backchannelmedia: Making Television 'Clickable'." Harvard Business School Case 509-026, April 2009. (Revised August 2009.)
      • April 2009 (Revised May 2010)
      • Case

      Partners In Health: HIV Care in Rwanda

      By: Michael E. Porter, Scott S. Lee, Joseph Rhatigan and Jim Yong Kim
      In 2005, Partners in Health (PIH) was invited by the Rwandan Ministry of Health to assume responsibility for the management of public health care in two rural districts in Eastern Rwanda and create an HIV treatment program at these sites. PIH successfully implemented a... View Details
      Keywords: Developing Countries and Economies; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Service Delivery; Nonprofit Organizations; Expansion; Health Industry; Rwanda
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      Porter, Michael E., Scott S. Lee, Joseph Rhatigan, and Jim Yong Kim. "Partners In Health: HIV Care in Rwanda." Harvard Business School Case 709-474, April 2009. (Revised May 2010.)
      • April 2009 (Revised July 2009)
      • Module Note

      Delivering Personally on Responsibility

      By: Joshua D. Margolis
      How can individuals equip themselves to exercise leadership in the face of moral adversity? This six-session module aims to prepare students to meet moral responsibility when it is simultaneously most essential and most difficult. Moral adversity refers to situations... View Details
      Keywords: Ethics; Leadership; Moral Sensibility; Leadership Development
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      Margolis, Joshua D. "Delivering Personally on Responsibility." Harvard Business School Module Note 409-093, April 2009. (Revised July 2009.)
      • 2009
      • Working Paper

      Prices or Knowledge? What Drives Demand for Financial Services in Emerging Markets?

      By: Shawn A. Cole, Thomas Sampson and Bilal Zia
      Financial development is critical for growth, but its micro-determinants are not well understood. We test leading theories of low demand for financial services in emerging markets, combining novel survey evidence from Indonesia and India with a field experiment. We... View Details
      Keywords: Banks and Banking; Saving; Knowledge Acquisition; Emerging Markets; Motivation and Incentives; Financial Services Industry; India; Indonesia
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      Cole, Shawn A., Thomas Sampson, and Bilal Zia. "Prices or Knowledge? What Drives Demand for Financial Services in Emerging Markets?" Harvard Business School Working Paper, No. 09-117, April 2009. (Revised October 2009, September 2010, October 2010.)
      • January 2009 (Revised February 2009)
      • Case

      Sydney IVF: Stem Cell Research

      By: Robert L. Simons, Kathryn Rosenberg and Natalie Kindred
      This case examines the strategy implementation and risk management decisions at Sydney IVF, a research-based in vitro fertilization and stem cell company based in Australia. Drs. Robert Jansen and Jock Anderson, who co-founded Sydney IVF in 1986, developed novel... View Details
      Keywords: Ethics; Governing Rules, Regulations, and Reforms; Innovation and Management; Growth and Development Strategy; Risk Management; Genetics; Commercialization; Health Industry; Australia
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      Simons, Robert L., Kathryn Rosenberg, and Natalie Kindred. "Sydney IVF: Stem Cell Research." Harvard Business School Case 109-017, January 2009. (Revised February 2009.)
      • January 2009
      • Case

      Xi'an International University: The Growth of Private Universities in China

      By: William C. Kirby, Michael Shih-ta Chen, Keith Chi-ho Wong and Tracy Manty
      Huang Teng founded Xi'an International University (XAIU) as a private institute of higher education in 1992. Throughout its ensuing years, the school filled a niche and met the demand of students who did not test into one of China's public institutions. In 2008, it was... View Details
      Keywords: Higher Education; Growth and Development Strategy; Private Ownership; Expansion; Education Industry; China
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      Kirby, William C., Michael Shih-ta Chen, Keith Chi-ho Wong, and Tracy Manty. "Xi'an International University: The Growth of Private Universities in China." Harvard Business School Case 309-074, January 2009.
      • 2009
      • Other Book

      A Test of a Company's Business Model

      By: Kenneth A. Merchant and Tatiana Sandino
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      Merchant, Kenneth A., and Tatiana Sandino. A Test of a Company's Business Model. Chartered Institute of Management Accountants, 2009.
      • 2009
      • Other Unpublished Work

      Heterogeneous Technology Diffusion and Ricardian Trade Patterns

      By: William R. Kerr
      This study tests the importance of Ricardian technology differences for international trade. The developed panel includes both emerging and advanced economies, and particular attention is devoted to the variation exploited in empirical tests. The elasticity of export... View Details
      Keywords: Trade; Immigration; Competitive Advantage; Integration; Technology; United States
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      Kerr, William R. "Heterogeneous Technology Diffusion and Ricardian Trade Patterns". 2009.
      • August 2009
      • Article

      Mental Accounting and Small Windfalls: Evidence from an Online Grocer

      By: John Beshears and Katherine L. Milkman
      We study the effect of small windfalls on consumer spending decisions by comparing the purchases online grocery customers make when redeeming $10-off coupons with the purchases they make without coupons. Controlling for customer fixed effects and other variables, we... View Details
      Keywords: Mental Accounting; Windfalls; Marginal Propensity To Consume; Coupons; Marketing Communications; Consumer Behavior; Accounting; Cognition and Thinking; Retail Industry
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      Beshears, John, and Katherine L. Milkman. "Mental Accounting and Small Windfalls: Evidence from an Online Grocer." Journal of Economic Behavior & Organization 71, no. 2 (August 2009): 384–394.
      • December 2008 (Revised January 2011)
      • Case

      Arcadia Biosciences: Seeds of Change

      By: Arthur A. Daemmrich, Forest L. Reinhardt and Mary Louise Shelman
      Arcadia Biosciences is an entrepreneurial California agricultural biotech company seeking to earn carbon credits by modifying commodity crops for use in China and India. Eric Rey, Arcadia's CEO, faced a strategic inflection point in early September 2008. The company... View Details
      Keywords: Business Startups; Entrepreneurship; Growth and Development Strategy; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Biotechnology Industry; China; India; California
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      Daemmrich, Arthur A., Forest L. Reinhardt, and Mary Louise Shelman. "Arcadia Biosciences: Seeds of Change." Harvard Business School Case 709-019, December 2008. (Revised January 2011.)
      • October 2008
      • Case

      Diagnostic Genomics

      By: Regina E. Herzlinger and Mark P. Allyn
      Should this gene detection firm enter the business of providing tests for the detection of genetic diseases? If so, how should it prioritize the tests it could develop? View Details
      Keywords: Health Testing and Trials; Market Entry and Exit; Product Development; Genetics; Strategy; Health Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Mark P. Allyn. "Diagnostic Genomics." Harvard Business School Case 309-040, October 2008.
      • 2008
      • Working Paper

      Just Keep My Money! Supporting Tax-time Savings with U.S. Savings Bonds

      By: Peter Tufano
      This paper reports the results of a 2007 experiment testing if specific process simplification can foster increased take-up rates for savings products, particularly by low-to-moderate income (LMI) households. Tax refund recipients at certain H&R Block tax preparation... View Details
      Keywords: Household; Income; Bonds; Investment; Personal Finance; Saving; Taxation; United States
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      Tufano, Peter. "Just Keep My Money! Supporting Tax-time Savings with U.S. Savings Bonds." Harvard Business School Working Paper, No. 09-059, October 2008. (Revised August 2010.)
      • October 2008
      • Article

      Organizational Responses to Environmental Demands: Opening the Black Box

      By: Magali Delmas and Michael W. Toffel
      This paper combines new and old institutionalism to explain differences in organizational strategies. We propose that differences in the influence of corporate departments lead their facilities to prioritize different external pressures and thus adopt different... View Details
      Keywords: Environmental Sustainability; Management Practices and Processes; Decisions; Adoption
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      Delmas, Magali, and Michael W. Toffel. "Organizational Responses to Environmental Demands: Opening the Black Box." Strategic Management Journal 29, no. 10 (October 2008): 1027–1055.
      • September 2008
      • Background Note

      Background on the Technology of Molecular Diagnostics

      By: Regina E. Herzlinger and Jason Sanders
      To be used as background reading for the "EXACT Sciences Corp.: Commercializing a Diagnostic Test" and "Diagnostic Genomics" cases, HBS nos. 308-090 and 309-040. View Details
      Keywords: Health Testing and Trials; Technology; Biotechnology Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Jason Sanders. "Background on the Technology of Molecular Diagnostics." Harvard Business School Background Note 309-050, September 2008.
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