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  • January 2014
  • Supplement

Amgen Inc.: Pursuing Innovation and Imitation? (B)

By: Ian Mackenzie
The (B) case reveals that Sharer decided that Amgen should enter the emerging biosimilars business. However, he took the better part of a year to syndicate the decision across the senior team while in parallel investing in some time-critical process development. The... View Details
Keywords: Corporate Strategy; Pharmaceutical Industry; Biotechnology Industry; United States
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Mackenzie, Ian. "Amgen Inc.: Pursuing Innovation and Imitation? (B)." Harvard Business School Supplement 714-426, January 2014.
  • 18 Jun 2024
  • Research & Ideas

Central Banks Missed Inflation Red Flags. This Pricing Model Could Help.

environments.” If central banks had used economic models that account for variations in the speed of firm’s pricing decisions rather than their traditional forecasting tools, policymakers might have detected rising inflation sooner,... View Details
Keywords: by Rachel Layne; Financial Services; Banking
  • March 2006
  • Module Note

Managing Innovation in an Uncertain World: Module 4: Sensing Opportunity

By: Alan D. MacCormack
Describes the fourth module of the 30-session Harvard Business School elective course Managing Innovation in an Uncertain World. The course helps students understand the challenges that uncertainty implies for innovation and how to overcome them. The course emphasizes... View Details
Keywords: Innovation and Management; Problems and Challenges; Management Analysis, Tools, and Techniques; Projects; Opportunities; Risk and Uncertainty; Perspective; Value Creation; Networks; Alignment
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MacCormack, Alan D. "Managing Innovation in an Uncertain World: Module 4: Sensing Opportunity." Harvard Business School Module Note 606-104, March 2006.
  • 07 Oct 2015
  • What Do You Think?

What is the Best Immigration Model for the US?

beliefs that they share are different.” Bowlweevils, injecting a political note into a discussion intended to deal with economics, argued that Germany has no model for dealing with immigrants and asylum seekers. As he put it, “Germany ...... View Details
Keywords: by James Heskett
  • April 2011
  • Article

Private Equity and Long-Run Investment: The Case of Innovation

By: Josh Lerner, Morten Sorensen and Per Stromberg
A long-standing controversy is whether LBOs relieve managers from short-term pressures of dispersed shareholders, or whether LBO funds themselves are driven by short-term profit motives and sacrifice long-term growth to boost short-term performance. We investigate 495... View Details
Keywords: Patents; Private Equity; Leveraged Buyouts; Investment; Innovation and Invention
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Lerner, Josh, Morten Sorensen, and Per Stromberg. "Private Equity and Long-Run Investment: The Case of Innovation." Journal of Finance 66, no. 2 (April 2011): 445–477.
  • February 2002
  • Case

NeuroTherapy Ventures: Catalyzing Neurologic Innovations

Discusses the impact of limited market size on epilepsy therapies and shows how an early-stage venture fund can catalyze faster development of new treatments. View Details
Keywords: Information Technology; Commercialization; Innovation and Management; Business Startups; Pharmaceutical Industry
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Chesbrough, Henry W. "NeuroTherapy Ventures: Catalyzing Neurologic Innovations." Harvard Business School Case 602-124, February 2002.
  • 2020
  • Working Paper

The Effects of Hierarchy on Learning and Performance in Business Experimentation

By: Sourobh Ghosh, Stefan Thomke and Hazjier Pourkhalkhali
Do senior managers help or hurt business experiments? Despite the widespread adoption of business experiments to guide strategic decision-making, we lack a scholarly understanding of what role senior managers play in firm experimentation. Using proprietary data of live... View Details
Keywords: Experimentation; Innovation; Search; New Product Development; Innovation and Invention; Organizational Design; Learning; Performance
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Ghosh, Sourobh, Stefan Thomke, and Hazjier Pourkhalkhali. "The Effects of Hierarchy on Learning and Performance in Business Experimentation." Harvard Business School Working Paper, No. 20-081, February 2020.
  • March 2017 (Revised February 2025)
  • Case

Edwin Land: The Art and Science of Innovation

By: Tom Nicholas, Christopher T. Stanton and Matthew G. Preble
Throughout the second half of the 20th century, Polaroid first invented—and then continuously reinvented—the field of instant photography. Under the leadership of its mercurial founder Edwin Land, the company regularly released new instant cameras and films, often... View Details
Keywords: Instant Photography; Company History; Change Management; Disruption; Forecasting and Prediction; Entrepreneurship; Business History; Innovation Strategy; Disruptive Innovation; Innovation and Management; Intellectual Property; Patents; Product Marketing; Brands and Branding; Product Launch; Product Development; Chemical Industry; Consumer Products Industry; United States
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Nicholas, Tom, Christopher T. Stanton, and Matthew G. Preble. "Edwin Land: The Art and Science of Innovation." Harvard Business School Case 817-107, March 2017. (Revised February 2025.)
  • 1980
  • Book

Competition in an Open Economy: A Model Applied to Canada

By: R. E. Caves, M. E. Porter and A. M. Spence
Keywords: Competition; Business Model; Canada
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Caves, R. E., M. E. Porter, and A. M. Spence. Competition in an Open Economy: A Model Applied to Canada. Vol. 150, Harvard Economic Studies. Cambridge, MA: Harvard University Press, 1980.
  • January 2016
  • Case

Sentient Jet: The Uber of Private Jets

By: Anat Keinan and Sandrine Crener
Founded in 1999 in the Boston area, Sentient Jet had become a leading private aviation company in the United States. Its success was built on the introduction of a groundbreaking membership program that offered business travelers the flexibility and convenience of... View Details
Keywords: Private Jets; Private Aviation; Luxury; Luxury Service; Uber; Branding; Growth Strategy; Client Acquisition; Innovative Business Model; Disruptive Innovation; Collaborative Consumption; Disruption; Disruptive Business Model; Travel; Reputation Management; Sharing Economy; Word Of Mouth; Customer Engagement; Aircraft; Membership Programs; Loyalty Program; Brand Positioning; Brand Building; Brand Differentiation; Customer Service; Exceeding Consumer Expectations; 2-way Business Model; Marketing Partnerships; Netjet; Air Transportation; Entrepreneurship; Growth and Development Strategy; Air Transportation Industry
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Keinan, Anat, and Sandrine Crener. "Sentient Jet: The Uber of Private Jets." Harvard Business School Case 516-066, January 2016.
  • 2011
  • Working Paper

The Impact of Horizontal Mergers and Acquisitions in Price Competition Models

The question of what impact mergers and acquisitions have on key equilibrium performance measures is fundamental to our understanding of competitive dynamics in an oligopolistic industry. We address these questions in the context of price competition models with... View Details
Keywords: Mergers and Acquisitions; Cost; Price; Profit; Duopoly and Oligopoly; Performance Efficiency; Mathematical Methods; Competition
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Federgruen, Awi, and Margaret P. Pierson. "The Impact of Horizontal Mergers and Acquisitions in Price Competition Models." Harvard Business School Working Paper, No. 12-031, October 2011.
  • 2022
  • Chapter

Immigration Policy Levers for U.S. Innovation and Startups

By: William R. Kerr and Sari Pekkala Kerr
Immigrants account for about a quarter of US invention and entrepreneurship despite a policy environment that is not well suited for these purposes. This chapter reviews the U.S. immigration policy environment that governs how skilled migrants move to America for... View Details
Keywords: High-tech; H1-B; Immigration; Entrepreneurship; Innovation and Invention; Business Startups; Venture Capital
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Kerr, William R., and Sari Pekkala Kerr. "Immigration Policy Levers for U.S. Innovation and Startups." In Innovation and Public Policy, edited by Austan D. Goolsbee and Benjamin F. Jones. Chicago: University of Chicago Press, 2022.
  • October 2006 (Revised October 2007)
  • Case

Information Technology and Innovation at Shinsei Bank

Shinsei Bank was rebuilt from the ashes of a failed predecessor, and pioneered new levels of customer service in retail banking in Japan. The bank's information technology, however, was vestigial at best and not well suited to the new service models Shinsei was... View Details
Keywords: Information Technology; Banks and Banking; Innovation and Invention; Banking Industry; Japan
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Upton, David M., and Virginia Fuller. "Information Technology and Innovation at Shinsei Bank." Harvard Business School Case 607-010, October 2006. (Revised October 2007.)
  • March 2006
  • Module Note

Managing Innovation in an Uncertain World: Module 3: Expanding Diversity

By: Alan D. MacCormack
Describes the third module of the 30-session Harvard Business School elective course Managing Innovation in an Uncertain World. The course helps students understand the challenges that uncertainty implies for innovation and how to overcome them. The course emphasizes... View Details
Keywords: Innovation and Management; Business Processes; Projects; Risk and Uncertainty; Product Development; Managerial Roles; Opportunities; Perspective; Expansion; Goals and Objectives
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MacCormack, Alan D. "Managing Innovation in an Uncertain World: Module 3: Expanding Diversity." Harvard Business School Module Note 606-126, March 2006.
  • 02 Apr 2015
  • Research & Ideas

Digital Initiative Summit: Freeing Patient Data to Enable Innovation

being engaged and given incentive to change. I don't know what tool or technology could be used for that, but anything that improves communication between and with providers, that kind of standardization, would be huge." Other Articles In This Series Big Messages,... View Details
Keywords: Re: Karim R. Lakhani; Health
  • May 2000
  • Case

CMGI: Organizational and Market Innovation

By: Josh Lerner
CMGI is considering acquiring yesmail, an e-mail marketing firm. In assessing the potential acquisition, it must assess the fit with its own organization, which consists of a unique blend of venture capital investments and publicly traded subsidiaries. View Details
Keywords: Innovation and Invention; Organizational Change and Adaptation; Mergers and Acquisitions; Organizational Structure; Venture Capital; Business Subsidiaries
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Lerner, Josh. "CMGI: Organizational and Market Innovation." Harvard Business School Case 200-064, May 2000.
  • November 2000
  • Article

A Buy-Side Model of M&A Lockups: Theory and Evidence

By: Guhan Subramanian and John C. Coates
Keywords: Theory; Mergers and Acquisitions
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Subramanian, Guhan, and John C. Coates. "A Buy-Side Model of M&A Lockups: Theory and Evidence." Stanford Law Review 53, no. 2 (November 2000): 307–396. (Selected by academics as one of the 'top ten' articles in corporate/securities law for 2001, out of 300 articles published in that year.)
  • 19 Jul 2004
  • Research & Ideas

Why Innovations Sit on the Shelf

For the most part, this requires management to look closely at the roles of various parts of the business and alter the way employees interact. Increasing the pace of business View Details
Keywords: by Michael Beer, Russell Eisenstat & Derek Schrader
  • February 2017 (Revised June 2017)
  • Supplement

ExxonMobil: Business as Usual? (B)

By: George Serafeim, Shiva Rajgopal and David Freiberg
The case presents ExxonMobil's response to growing pressure to disclose how climate change will impact their business. This includes multiple asset impairments and losing a proxy vote to shareholders to increase climate change related reporting. Supplements the (B)... View Details
Keywords: Oil & Gas; Oil Prices; Oil Companies; Asset Impairment; Predictive Analytics; Sustainability; Environmental Impact; Innovation; Disclosure; Accounting; Valuation; Energy Sources; Ethics; Corporate Disclosure; Governance Compliance; Climate Change; Financial Reporting; Energy Industry; United States
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Serafeim, George, Shiva Rajgopal, and David Freiberg. "ExxonMobil: Business as Usual? (B)." Harvard Business School Supplement 117-047, February 2017. (Revised June 2017.)
  • August 2024
  • Case

Sky Therapeutics: Innovating in Digital Therapeutics

By: Satish Tadikonda, Olivia Reszczynski and William Marks
Shad Faraz and Alex Youssef were intrigued by the opportunities in the relatively new area of Digital Therapeutics. Despite initial successes, early entrants had struggled with reimbursement and revenue-predictability challenges. However, venture investors still... View Details
Keywords: Business Startups; Entrepreneurship; Mission and Purpose; Health Care and Treatment; Technological Innovation; Business Strategy; Health Industry; Technology Industry
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Tadikonda, Satish, Olivia Reszczynski, and William Marks. "Sky Therapeutics: Innovating in Digital Therapeutics." Harvard Business School Case 825-071, August 2024.
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