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January 2017 (Revised December 2017)
Case

Carmichael Roberts: To Create a Private Equity Firm?

By: Steven Rogers and Kenneth J. Cooper

Carmichael Roberts, a rare African-American venture capitalist, considered leaving his general partnership in a private equity firm near Boston and setting up his own in 2015. He weighed whether the timing was right, with the economy still not fully recovered from the... View Details

2006
Book

Science Business: The Promise, the Reality, and the Future of Biotech

By: Gary P. Pisano

Why has the biotechnology industry failed to perform up to expectations—despite all its promise? In Science Business, Gary P. Pisano answers this question by providing an incisive critique of the industry. Pisano not only reveals the underlying causes of... View Details

Keywords: Science; Business Ventures; Biotechnology Industry

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June 2006 (Revised April 2007)
Case

BioScale

By: H. Kent Bowen and Bradley R. Staats

In 2004, Mark Lundstrom must decide on a funding method and strategic approach for BioScale, a biotechnology company that he founded. BioScale has developed a microchip-based bioanalytical platform that can be used to detect very small concentrations of cells, viruses,... View Details

Keywords: Entrepreneurship; Science-Based Business; Capital; Financing and Loans; Partners and Partnerships; Biotechnology Industry

Teaching Interest

Strategy and Technology

Overview

This course explores the unique aspects of creating effective management and investment strategies for technology-intensive businesses. What are effective strategies for winning in markets with strong network effects? How should... View Details

Keywords: Strategy; Technology

December 2022 (Revised February 2023)
Case

Marfrig's Quest for Sustainable Beef

By: Jose B. Alvarez, Pedro Levindo and Ruth Costas

Marfrig, one of the world’s leading meatpackers, strived to comply with its commitment to have a deforestation-free value chain in Brazil by 2030. The company also pledged to reduce its emissions of greenhouse gases in accordance with the guidelines set by the... View Details

Keywords: Agribusiness; Animal-Based Agribusiness; Plant-Based Agribusiness; Acquisition; Family Business; Communication Strategy; Environmental Management; Climate Change; Environmental Regulation; Environmental Sustainability; Bonds; Food; Global Strategy; Goods and Commodities; Government and Politics; Political Elections; Leading Change; Marketing; Product Marketing; Product Positioning; Supply Chain; Supply Chain Management; Corporate Social Responsibility and Impact; Business and Government Relations; Business and Stakeholder Relations; Partners and Partnerships; Strategy; Adaptation; Business Strategy; Commercialization; Competitive Strategy; Corporate Strategy; Diversification; Expansion; Agriculture and Agribusiness Industry; Food and Beverage Industry; Brazil; Latin America; Argentina; Uruguay; North America; United States; Europe; Asia; China

Article

Lessons From Hollywood: A New Approach To Funding R&D

By: Gary P. Pisano and Andrew W. Lo

Companies find it increasingly difficult to justify long-term, risky R&D investments—particularly in science-based fields such as biotechnology, advanced materials, and energy. We argue in this article that the traditional venture model has limits for such investments... View Details

Keywords: Financial Innovation; Financial Strategy; Project Management; R＆D; Start-up; Innovation Strategy; Business Model; Research and Development; Financial Management; Risk Management; Strategy

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January 2017 (Revised March 2017)
Case

Royal DSM: From Continuous Transformation to Organic Growth

By: William W. George, Carin-Isabel Knoop and Amram Migdal

Royal DSM CEO Feike Sijbesma was pondering the challenges of shifting DSM’s global organization from the constant transformations of the past 100 years to creating organic growth. When Sijbesma took the helm as CEO in 2007, he further pushed and completed the company’s... View Details

Keywords: Organic Growth; Organizational Change; M＆A; Mergers And Acquisitions; Divestment; Business Ventures; Business Divisions; Business Growth and Maturation; Restructuring; Change; Change Management; Transformation; Transition; Engineering; Chemicals; Mining; Ethics; Values and Beliefs; Finance; Capital Markets; Financial Markets; Food; Globalization; Global Strategy; Globalized Firms and Management; Globalized Markets and Industries; Health; Nutrition; History; Leadership; Leadership Development; Leadership Style; Leading Change; Management; Business or Company Management; Growth and Development Strategy; Growth Management; Management Practices and Processes; Management Style; Organizations; Corporate Social Responsibility and Impact; Mission and Purpose; Organizational Change and Adaptation; Organizational Culture; Organizational Design; Ownership; Public Ownership; Performance; Strategy; Adaptation; Consolidation; Corporate Strategy; Value; Value Creation; Biotechnology Industry; Chemical Industry; Food and Beverage Industry; Mining Industry; Pharmaceutical Industry; Europe; Netherlands

09 Sep 2010
Working Paper Summaries

Boundary Spanning in a For-Profit Research Lab: An Exploration of the Interface Between Commerce and Academe

Keywords: by Christopher C. Liu & Toby E. Stuart; Biotechnology

March 2024 (Revised July 2024)
Case

WeightWatchers: Promoting Weight Health

By: Ranjay Gulati, Cynthia A. Montgomery, Ashley Whillans, Allison Ciechanover and Emily Grandjean

In December 2023, the 60-year-old weight management industry stalwart WeightWatchers announced the launch of WeightWatchers Clinic, which incorporated GLP-1s , a new class of prescription weight-loss medications, into the company’s portfolio of products and mobile app... View Details

Keywords: Business Strategy; Competitive Strategy; Resource Allocation; Diversification; Leadership; Growth and Development Strategy; Technology Industry; Health Industry; Pharmaceutical Industry; United States; New York (city, NY)

March 2008 (Revised April 2008)
Case

Corning: 156 Years of Innovation

By: H. Kent Bowen and Courtney Purrington

The executive team at Corning has committed to double the rate of new business creation per decade, while at the same time growing the company's current businesses, including glass substrates for LCD displays. Their strategy, built on more than 150 years of successful... View Details

Keywords: Innovation Leadership; Resource Allocation; Product Development; Research and Development; Science-Based Business; Industrial Products Industry

March 1999
Teaching Note

Conceptual Overview: "Business and the Environment," An Elective for MBA Students TN

By: Forest L. Reinhardt

Intended to assist faculty who teach courses on environmental management at business schools. Other people interested in the relationships between business and the environment may also find it useful. View Details

Keywords: Science-Based Business; Environmental Sustainability; Business Education; Theory

November 2016 (Revised November 2016)
Case

Radial Analytics Probes Post-Acute Care

By: Richard G. Hamermesh and Olivia Hull

Thaddeus Fulford-Jones and Eric Weiss, founders of healthcare technology startup Radial Analytics, have been busy developing a software program designed to save hospitals money and improve patient outcomes by producing customized care plans for patients leaving the... View Details

Keywords: Electronic Medical Records; Electronic Health Records; Data Science; Entrepreneurship; Health Care and Treatment; Business Model; Business Startups; Innovation and Invention; Growth Management; Marketing Strategy; Product Launch; Product Positioning; Science-Based Business; Business Strategy; Health Industry; Technology Industry; Cambridge; Massachusetts

06 Feb 2012
Research & Ideas

Kodak: A Parable of American Competitiveness

in the United States, but US companies gave it all up.” HBS Professor of Management Practice Willy C. Shih served as president of Kodak's Digital & Applied Imaging business through the turn of the 21st century. Shortly after starting... View Details

Keywords: by Dina Gerdeman; Manufacturing

February 2016 (Revised September 2017)
Case

Neurotrack and the Alzheimer's Puzzle

By: Richard G. Hamermesh, Liz Kind and Carin-Isabel Knoop

Elli Kaplan founded Neurotrack in 2012 with a breakthrough noninvasive cognitive diagnostics test that will detect Alzheimer's disease in its earliest pre-symptomatic stages. While the company has gained great traction in the three years since it was started, with no... View Details

Keywords: Alzheimer's Disease; Diagnostics; Healthcare; Entrepreneurship; Health Disorders; Science-Based Business; Business Model; Medical Devices and Supplies Industry; United States

January 2013
Supplement

Cabot Corporation: The Fuel Cell Decision (B)

By: Willy Shih and Ying Zhou

Managers at Cabot Corporation are faced with deciding the future of its fuel cell program. The (A) case recounts the view of the business manager and the technical project lead, and the (B) case describes the perspective of a senior manager who is the head of the New... View Details

June 2004 (Revised November 2004)
Case

Acorda Therapeutics: Rebuilding the Spinal Cord

Acorda is an early-stage life science start-up with a promising product that is close to reaching the market (Phase III clinical trials). The company is grappling with how to expand its portfolio of molecules to make the business more sustainable. It faces classic... View Details

Keywords: Decision Making; Science-Based Business; Health Testing and Trials; Business Startups; Product Development; Biotechnology Industry

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13 Nov 2006
Research & Ideas

Science Business: What Happened to Biotech?

"anatomy," has created poor conditions for a science-based business to flower. "The sector has indiscriminately borrowed business models, organizational... View Details

Keywords: by Sean Silverthorne; Biotechnology

September 2007 (Revised May 2011)
Case

Commercializing an MRI Breakthrough

The challenges and best strategies for the commercialization of university technologies are illustrated in this case which documents an MRI breakthrough that arose from the Charles Marcus laboratory at Harvard. Students discuss the interdependencies of intellectual... View Details

Keywords: Business Model; Decision Choices and Conditions; Higher Education; Patents; Research and Development; Science-Based Business; Commercialization

July 2004 (Revised March 2006)
Case

RosettaNet and ebXML: Betting on the Right eBusiness Standard

By: F. Warren McFarlan and Veronika Belokhvostova

A major enterprise software company must select which technologies to support, based on their long-term and short-term viability and benefits. The protagonist is involved in the release of the B2B integration component of major enterprise software whose purpose is to... View Details

Keywords: Communication Technology; Customer Focus and Relationships; Markets; Standards; Science-Based Business; Situation or Environment; Applications and Software; Technology Adoption; Information Technology Industry

26 Mar 2012
Research & Ideas

What Neuroscience Tells Us About Consumer Desire

brain-tracking tools to determine why we prefer some products over others. "People are fairly good at expressing what they want, what they like, or even how much they will pay for an item," says Uma R. Karmarkar, an assistant professor at Harvard View Details

Keywords: by Carmen Nobel; Consumer Products

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