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      Open Source InnovationRemove Open Source Innovation →

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      • July 2024
      • Case

      Gates Ventures: Making Alzheimer's a Forgotten Past

      By: Satish Tadikonda, William Marks, Shardule Shah and Calvin Marambo
      After a personal journey and interest in Alzheimer's Disease (AD) by Bill Gates, Gates Ventures set out to find the best way to accelerate innovation in the field of AD. In partnership with the Alzheimer's Drug Discovery Foundation, Gates Ventures created the... View Details
      Keywords: Philanthropy and Charitable Giving; Entrepreneurial Finance; Health Disorders; Mission and Purpose
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      Tadikonda, Satish, William Marks, Shardule Shah, and Calvin Marambo. "Gates Ventures: Making Alzheimer's a Forgotten Past." Harvard Business School Case 824-075, July 2024.
      • June 2024 (Revised September 2024)
      • Case

      Driving Scale with Otto

      By: Rebecca Karp, David Allen and Annelena Lobb
      This case asks how startup founders make scaling decisions in light of their priorities for their business and for themselves. Otto was a technology company that applied artificial intelligence technology to sales. It deployed natural language processing to find sales... View Details
      Keywords: Artificial Intelligence; Natural Language Processing; B2B; B2B Innovation; Scaling; Scaling Tech Ventures; Business Startups; AI and Machine Learning; Finance; Sales; Business Strategy; Growth and Development Strategy; Entrepreneurship; Information Technology Industry; United States; Cambridge; New York (city, NY); Spain
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      Karp, Rebecca, David Allen, and Annelena Lobb. "Driving Scale with Otto." Harvard Business School Case 724-407, June 2024. (Revised September 2024.)
      • 2024
      • Working Paper

      The Value of AI Innovations

      By: Wilbur Xinyuan Chen, Terrence Tianshuo Shi and Suraj Srinivasan
      We study the value of AI innovations as it diffuses across general and application sectors, using the United States Patent and Trademark Office’s (USPTO) AI patent dataset. Investors value these innovations more than others, as AI patents exhibit a 9% value premium,... View Details
      Keywords: AI and Machine Learning; Valuation; Technological Innovation; Open Source Distribution; Patents; Policy; Knowledge Sharing; Technology Industry
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      Chen, Wilbur Xinyuan, Terrence Tianshuo Shi, and Suraj Srinivasan. "The Value of AI Innovations." Harvard Business School Working Paper, No. 24-069, May 2024.
      • May 2024
      • Teaching Note

      AI Wars

      By: Andy Wu and Matt Higgins
      Teaching Note for HBS Case No. 723-434. In 2024, the world was looking to Google to see what the search giant and long-time putative technical leader in artificial intelligence (AI) would do to compete in the massively hyped technology of generative AI popularized over... View Details
      Keywords: AI; Trends; AI and Machine Learning; Public Opinion; Technological Innovation; Competitive Advantage; Technology Industry
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      Wu, Andy, and Matt Higgins. "AI Wars." Harvard Business School Teaching Note 724-482, May 2024.
      • May 2024
      • Teaching Note

      AI21 Labs in 2023: Strategy for Generative AI

      By: David Yoffie
      Teaching Note for HBS Case 724-383. The case has 3 important teaching purposes: First, what are the advantages and disadvantages of imitation? (e.g., Should AI21 imitate OpenAI with a chatbot?) Second, what are the advantages and disadvantages of keeping new technology... View Details
      Keywords: AI; Generative Ai; Generative Models; AI and Machine Learning; Innovation Strategy; Growth and Development Strategy; Business Model; Business Startups; Open Source Distribution; Competitive Advantage; Technology Industry; Israel
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      Yoffie, David. "AI21 Labs in 2023: Strategy for Generative AI." Harvard Business School Teaching Note 724-461, May 2024.
      • May 2024
      • Article

      Financial Innovation in the 21st Century: Evidence from U.S. Patents

      By: Josh Lerner, Amit Seru, Nick Short and Yuan Sun
      We develop a unique dataset of 24 thousand U.S. finance patents granted over the last two decades to explore the evolution and production of financial innovation. We use machine learning to identify the financial patents and extensively audit the results to ensure... View Details
      Keywords: Banking; Investment Banks; Information Technology; Regulation; Patents; Innovation and Invention; Trends
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      Lerner, Josh, Amit Seru, Nick Short, and Yuan Sun. "Financial Innovation in the 21st Century: Evidence from U.S. Patents." Journal of Political Economy 132, no. 5 (May 2024): 1391–1449.
      • 2024
      • Working Paper

      Old Moats for New Models: Openness, Control, and Competition in Generative AI

      By: Pierre Azoulay, Joshua L. Krieger and Abhishek Nagaraj
      Drawing insights from the field of innovation economics, we discuss the likely competitive environment shaping generative AI advances. Central to our analysis are the concepts of appropriability—whether firms in the industry are able to control the knowledge generated... View Details
      Keywords: Technological Innovation; AI and Machine Learning; Open Source Distribution; Policy
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      Azoulay, Pierre, Joshua L. Krieger, and Abhishek Nagaraj. "Old Moats for New Models: Openness, Control, and Competition in Generative AI." NBER Working Paper Series, No. 7442, May 2024.
      • March 2024 (Revised July 2024)
      • Case

      H2 Green Steel: A Clean-Tech Triple Play?

      By: Debora L. Spar, Gunnar Trumbull, Henry Tao and Julia Comeau
      At the end of 2023, the Swedish startup H2 Green Steel was mid-way through construction on an integrated steel plant in Northern Sweden that would use abundant local hydro power to create Europe’s first commercial-scale green steel. Their goal was to help European... View Details
      Keywords: Steel; Green Business; Green Technology; Factories, Labs, and Plants; Business Startups; Climate Change; Technological Innovation; Growth and Development Strategy; Renewable Energy; Steel Industry; Sweden
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      Spar, Debora L., Gunnar Trumbull, Henry Tao, and Julia Comeau. "H2 Green Steel: A Clean-Tech Triple Play?" Harvard Business School Case 324-101, March 2024. (Revised July 2024.)
      • March 2024 (Revised May 2024)
      • Case

      Amperity: First-Party Data at a Crossroads

      By: Elie Ofek, Hema Yoganarasimhan and Alexis Lefort
      In the summer of 2023, Amperity management was facing a critical decision on its future direction. Given the dramatic changes occurring within the digital advertising ecosystem, as concerns over consumer privacy placed limits on the ability to engage in third-party... View Details
      Keywords: AI and Machine Learning; Technology Adoption; Business Strategy; Digital Marketing; Price; Product; Business or Company Management; Advertising Industry
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      Ofek, Elie, Hema Yoganarasimhan, and Alexis Lefort. "Amperity: First-Party Data at a Crossroads." Harvard Business School Case 524-017, March 2024. (Revised May 2024.)
      • March 2024
      • Case

      From 'BIG' Ideas to Sustainable Impact at ICL Group (A)

      By: Linda A. Hill and Lydia Begag
      In the summer of 2023, Eduard (“Eddie”) Croitoru, Vice President (VP) of ICL Group (“ICL”) Corporate Initiatives, was reflecting on ICL’s internal ideation program, the Business Innovation for Growth (BIG) Accelerator. When Raviv Zoller became the CEO of ICL in 2018,... View Details
      Keywords: Change Management; Agribusiness; Accounting; Communication; Renewable Energy; Chemicals; Machinery and Machining; Metals and Minerals; Mining; Social Entrepreneurship; Corporate Entrepreneurship; Values and Beliefs; Environmental Sustainability; Natural Resources; Globalization; Information Technology; Collaborative Innovation and Invention; Leadership; Organizational Culture; Personal Development and Career; Talent and Talent Management; Manufacturing Industry; Agriculture and Agribusiness Industry; Chemical Industry; Israel; China; United States
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      Hill, Linda A., and Lydia Begag. "From 'BIG' Ideas to Sustainable Impact at ICL Group (A)." Harvard Business School Case 424-042, March 2024.
      • March 2024 (Revised April 2024)
      • Supplement

      From 'BIG' Ideas to Sustainable Impact at ICL Group (B)

      By: Linda A. Hill and Lydia Begag
      In August 2023, Raviv Zoller, CEO of ICL Group, discussed his upcoming business trip to St. Louis with Eduard Croitoru, VP of ICL Corporate Initiatives, to commemorate the construction of ICL's new $400 million advanced manufacturing facility. In preparation for the... View Details
      Keywords: Change Management; Agribusiness; Accounting; Communication; Renewable Energy; Chemicals; Machinery and Machining; Metals and Minerals; Mining; Social Entrepreneurship; Corporate Entrepreneurship; Values and Beliefs; Environmental Sustainability; Natural Resources; Globalization; Information Technology; Collaborative Innovation and Invention; Leadership; Organizational Culture; Personal Development and Career; Partners and Partnerships; Manufacturing Industry; Agriculture and Agribusiness Industry; Chemical Industry; Battery Industry; Israel; United States; China
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      Hill, Linda A., and Lydia Begag. "From 'BIG' Ideas to Sustainable Impact at ICL Group (B)." Harvard Business School Supplement 424-043, March 2024. (Revised April 2024.)
      • March 2024 (Revised June 2025)
      • Teaching Note

      CoPilot(s): Generative AI at Microsoft and GitHub

      By: Frank Nagle and Maria P. Roche
      This teaching note is the companion to case N9-624-010 CoPilot(s): Generative AI at Microsoft and GitHub, which takes place in late 2021. The case briefly describes the history of both GitHub and Microsoft with a particular focus on open source software (OSS)—software... View Details
      Keywords: Mergers and Acquisitions; AI and Machine Learning; Applications and Software; Technological Innovation; Product Launch; Open Source Distribution; Product Development; Commercialization; Competition; Resource Allocation; Technology Industry
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      Nagle, Frank, and Maria P. Roche. "CoPilot(s): Generative AI at Microsoft and GitHub." Harvard Business School Teaching Note 724-452, March 2024. (Revised June 2025.)
      • March 2024 (Revised May 2025)
      • Case

      Governing OpenAI (A)

      By: Lynn S. Paine, Suraj Srinivasan and Will Hurwitz
      In late November 2023, OpenAI’s new board of directors took stock of the situation. The company, which sought to develop artificial general intelligence (AGI)—computer systems with capabilities exceeding human abilities—was looking to regain its footing after a chaotic... View Details
      Keywords: Artificial Intelligence; Board Of Directors; Board Decisions; Board Dynamics; Corporate Boards; Governance Changes; Governance Structure; Leadership Change; Legal Aspects Of Business; Nonprofit Governance; Strategy And Execution; Technological Change; AI and Machine Learning; Corporate Governance; Leadership; Management; Mission and Purpose; Technological Innovation; Governing Rules, Regulations, and Reforms; Governing and Advisory Boards; Resignation and Termination; Ethics; Nonprofit Organizations; Open Source Distribution; Partners and Partnerships; Technology Industry; San Francisco; United States
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      Paine, Lynn S., Suraj Srinivasan, and Will Hurwitz. "Governing OpenAI (A)." Harvard Business School Case 324-103, March 2024. (Revised May 2025.)
      • March 2024
      • Supplement

      Toby Norman: Is Passion Enough for Simprints to Thrive? Decision: Mexico Deal vs. Open Source

      By: Jon M. Jachimowicz
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      Jachimowicz, Jon M. "Toby Norman: Is Passion Enough for Simprints to Thrive? Decision: Mexico Deal vs. Open Source." Harvard Business School Multimedia/Video Supplement 424-708, March 2024.
      • March 2024
      • Article

      Medicare Price Negotiation and Pharmaceutical Innovation Following the Inflation Reduction Act

      By: Matthew Vogel, Pragya Kakani, Amitabh Chandra and Rena M. Conti
      The Inflation Reduction Act (IRA) requires Medicare to negotiate lower prices for some medicines with high Medicare spending. Using historical data from public and proprietary sources to apply the IRA's negotiation criteria retrospectively, we identify all drugs that... View Details
      Keywords: Policy; Government Legislation; Health Care and Treatment; Negotiation; Price; Pharmaceutical Industry
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      Vogel, Matthew, Pragya Kakani, Amitabh Chandra, and Rena M. Conti. "Medicare Price Negotiation and Pharmaceutical Innovation Following the Inflation Reduction Act." Nature Biotechnology 42, no. 3 (March 2024): 406–412.
      • February 2024
      • Module Note

      Collaborate on the Core, Compete on the Edges

      By: Frank Nagle
      In the rapidly evolving environment of modern business, the digitization of economic activity and the ubiquitous integration of technology across industries are fundamentally altering how companies develop and implement strategy. The rise of digital technologies has... View Details
      Keywords: Technology Adoption; Competition; Cooperation; Collaborative Innovation and Invention
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      Nagle, Frank. "Collaborate on the Core, Compete on the Edges." Harvard Business School Module Note 724-453, February 2024.
      • February 2024
      • Case

      Horizon Quantum Computing

      By: Paul A. Gompers and Billy Chan
      In 2023, the Singapore-based startup company Horizon Quantum Computing was on the cusp of fast expansion and the founder faced the challenge to decide where to open the second office outside Singapore. To make a choice from the list of 10 countries, the founder had to... View Details
      Keywords: Business Plan; Entrepreneurship; Entrepreneurial Finance; Disruptive Innovation; Business Offices; Business Startups; Talent and Talent Management; Decision Choices and Conditions; Partners and Partnerships; Expansion; Information Technology Industry; Telecommunications Industry; Singapore; Asia
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      Gompers, Paul A., and Billy Chan. "Horizon Quantum Computing." Harvard Business School Case 224-049, February 2024.
      • February 2024 (Revised January 2025)
      • Case

      AGENTS.inc: Pathways to Growth at an AI Startup

      By: Frank Nagle, Manuel Hoffmann, Karoline Ströhlein and Susan Pinckney
      The case describes the history of AGENTS.inc. Despite being a small startup, with only four employees, that had never had a funding round, the company boasted an impressive client portfolio including multiple Fortune 500 companies. While AGENTS.inc had been an early... View Details
      Keywords: Business Growth and Maturation; Business Model; Business Startups; Small Business; Transformation; Customer Focus and Relationships; Decisions; Entrepreneurship; Venture Capital; Financial Strategy; AI and Machine Learning; Digital Platforms; Technological Innovation; Copyright; Management; Growth and Development; Market Timing; Ownership; Risk and Uncertainty; Competition; Open Source Distribution; Entrepreneurial Finance; Computer Industry; Europe; Germany
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      Nagle, Frank, Manuel Hoffmann, Karoline Ströhlein, and Susan Pinckney. "AGENTS.inc: Pathways to Growth at an AI Startup." Harvard Business School Case 724-444, February 2024. (Revised January 2025.)
      • February 2024
      • Case

      Can Cities Beat the Heat? (A): A Comparative Analysis of Climate Actions and Change Enablers in 14 U.S. Cities

      By: Rosabeth Moss Kanter and Jacob A. Small
      Throughout the early 2000's, emphasis was placed on initiatives to adapt to and mitigate climate action in cities. This series presents overviews (snapshots) of 14 U.S. metropolitan regions to help identify similarities, differences, and opportunities for developing... View Details
      Keywords: Climate; Climate Impact; Innovation; Mitigation Policies; Carbon Footprint; Investing; Climate Finance; Renewable; Mobility; City; Climate Change; Adaptation; Renewable Energy; Weather; Problems and Challenges; United States; Boston; Detroit; Miami; Minneapolis; St. Paul; Pittsburgh; Seattle; San Jose
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      Kanter, Rosabeth Moss, and Jacob A. Small. "Can Cities Beat the Heat? (A): A Comparative Analysis of Climate Actions and Change Enablers in 14 U.S. Cities." Harvard Business School Case 324-080, February 2024.
      • February 2024
      • Supplement

      Can Cities Beat the Heat? (B1): Birmingham Climate Action Snapshot

      By: Rosabeth Moss Kanter, Natania Elias and Jacob A. Small
      Climate snapshots provide a summary of climate actions that occurred between 2018 and 2024, highlighting major green initiatives, innovations, carbon mitigation strategy, and action across multiple levels of government and the private sector. Snapshots also provide an... View Details
      Keywords: Mitigation Policies; Carbon Footprint; Climate Finance; Mobility; Adaptation; Renewable Energy; Climate Change; Problems and Challenges; Sustainable Cities; City; Innovation Strategy; Investment; United States; Alabama
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      Kanter, Rosabeth Moss, Natania Elias, and Jacob A. Small. "Can Cities Beat the Heat? (B1): Birmingham Climate Action Snapshot." Harvard Business School Supplement 324-082, February 2024.
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