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September 2023 (Revised November 2023)
Case

Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab

By: George Serafeim and Michael Norris

In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company as he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in... View Details

Keywords: Business Model; Green Technology; Goods and Commodities; Growth and Development Strategy; Science-Based Business; Entrepreneurship; Plant-Based Agribusiness; Business Startups; Decisions; Technological Innovation; Production; Agriculture and Agribusiness Industry; Technology Industry; Boston; Sao Paulo

August 2023 (Revised August 2023)
Case

Sky Therapeutics: Innovating in Digital Therapeutics

By: Satish Tadikonda, Olivia Reszczynski and William Marks

Shad Faraz and Alex Youssef were intrigued by the opportunities in the relatively new area of Digital Therapeutics. Despite initial successes, early entrants had struggled with reimbursement and revenue-predictability challenges. However, venture investors still... View Details

Keywords: Business Startups; Entrepreneurship; Mission and Purpose; Health Industry; Technology Industry

July 2023
Case

Moderna: Everything, Everywhere, All at Once

By: Satish Tadikonda, Shikhar Ghosh and William Marks

Coming out of the COVID-19 pandemic, Moderna was riding the successes of developing a vaccine in record time and helping stem the tide of the crisis. However, the company had grown at an incredible rate, more than doubled its number of employees, and had to put on hold... View Details

Keywords: Health Pandemics; Selection and Staffing; Growth Management; Management Succession; Retirement; Technological Innovation; Corporate Strategy; Biotechnology Industry

June 2023
Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai

Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details

Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry

April 2023 (Revised February 2024)
Case

AI Wars

By: Andy Wu, Matt Higgins, Miaomiao Zhang and Hang Jiang

In February 2024, the world was looking to Google to see what the search giant and long-time putative technical leader in artificial intelligence (AI) would do to compete in the massively hyped technology of generative AI. Over a year ago, OpenAI released ChatGPT, a... View Details

Keywords: AI; Artificial Intelligence; AI and Machine Learning; Technology Adoption; Competitive Strategy; Technological Innovation

February 2023 (Revised May 2023)
Case

Accelerating the Accelerator: Raja Al Mazrouei at DIFC Fintech Hive

By: Linda A. Hill, Emily Tedards and Lydia Begag

In January 2023, Raja Al Mazrouei became the Managing Director and Acting CEO of Etihad Credit Insurance (ECI) in Dubai, UAE. In her previous role as the Executive Vice President of the DIFC Fintech Hive, she successfully built and led an accelerator program for... View Details

2023
Chapter

Organizational Development

By: Min Basadur, Tim Basadur and Goran Calic

Our review of the field of Organizational Development (OD) reveals an extensive range of tools which attempt to help organizations improve performance. We believe that OD should be studied differently: As a continuous process of change-making or innovation. How this... View Details

Keywords: Change; Cognition and Thinking; Creativity; Organizational Change and Adaptation; Innovation and Management

Register to Read

January 2023 (Revised May 2023)
Case

Steve Jobs: Changing the World

By: Robert Simons and Shirley Sun

This case traces the life of Steve Jobs who throughout his career flaunted convention and chose an unusual path to success. The case describes how Jobs, as young man, acquired an appreciation for aesthetics and the liberal arts, but was also quick to recognize and... View Details

Keywords: Entrepreneurship; Technology; Business Startups; Personal Characteristics; Leadership Style; Innovation; Work-life Balance; Innovation Leadership; Power and Influence; Success; Information Technology Industry; United States

December 2022 (Revised August 2023)
Case

Circles.Life at a Crossroads of Growth

By: Juan Alcácer and Adina Wong

In June 2022, the founders of Singapore mobile operator Circles.Life had a crucial decision to make. Circles.Life developed a new business model in mobile telecommunications—a digital telco—built around its proprietary operating system. After expanding its brand in... View Details

Keywords: Business Model; Decisions; Technological Innovation; Applications and Software; Business Strategy; Telecommunications Industry; Singapore

13 Oct 2022
Other Presentation

4 Business Ideas That Changed the World: Disruptive Innovation

By: Amy Bernstein, Rita McGrath, Felix Oberholzer-Gee and Derek van Bever

A roundtable conversation takes stock of Clayton Christensen’s influential theory. This first in a series of roundtable conversations assessing the origins and impact of four breakthrough ideas.

In the 1980s, Clayton Christensen cofounded a startup that... View Details

Keywords: Disruptive Innovation

October 2022 (Revised February 2024)
Case

Masdar City: Aiming for Sustainable and Profitable Real Estate

By: Boris Vallee and Fares Khrais

Masdar City broke ground in 2008 and was conceived by the Abu Dhabi government to be an international beacon of innovation in sustainable energy and real estate. It was also to be a profitable investment for the government. At first glance, the two goals pulled in... View Details

2022
Book

Empires of Ideas: Creating the Modern University from Germany to America to China

By: William C. Kirby

The modern university was born in Germany. In the twentieth century, the United States leapfrogged Germany to become the global leader in higher education. Will China challenge its position in the twenty-first?
Today American institutions dominate nearly every... View Details

Keywords: University; Higher Education; History; United States; Germany; China

Find at Harvard

June 2022 (Revised August 2023)
Case

Strategic Innovation at the United Nations: A Network of Ecosystems

By: Frank Nagle, Elizabeth J. Altman and Amy Klopfenstein

In 2021, Gina Lucarelli, leader of the United Nations Development Programme (UNDP) Accelerator Labs, prepared for a meeting with UNDP Administrator Achim Steiner. The two planned to discuss the future of the Accelerator Labs, a network of social innovation labs located... View Details

Keywords: Change; Disruption; Transformation; Change Management; Education; Learning; Environmental Management; Climate Change; Environmental Sustainability; Geography; Geographic Scope; Global Range; Local Range; Geopolitical Units; Country; Human Resources; Recruitment; Retention; Selection and Staffing; Employees; Employee Relationship Management; Information Technology; Information Management; Innovation and Invention; Collaborative Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Leadership; Innovation Strategy; Knowledge; Knowledge Acquisition; Knowledge Dissemination; Knowledge Management; Knowledge Sharing; Knowledge Use and Leverage; Organizations; Mission and Purpose; Organizational Culture; Organizational Structure; Organizational Design; Organizational Change and Adaptation; Social Enterprise; Non-Governmental Organizations; Social Psychology; Social and Collaborative Networks; Society; Social Issues; Welfare; Strategy; Cooperation; Adaptation; Public Administration Industry; North and Central America

June 2022
Teaching Note

Bespoken Spirits: Disrupting Distilling

By: Benjamin C. Esty and Daniel Fisher

Teaching Note for HBS Case No. 721-419. On October 7, 2020, Bespoken Spirits publicly announced it had received $2.6 million of seed funding for its “sustainable maturation process,” a process that could produce award-winning whiskeys in just days rather than years... View Details

Keywords: B2B Vs. B2C; Technological Innovation; Business Startups; Cost Management; Business Model; Consumer Products Industry; Food and Beverage Industry; Service Industry

2022
Book

The Digital Mindset: What It Really Takes to Thrive in the Age of Data, Algorithms, and AI

By: Paul Leonardi and Tsedal Neeley

The pressure to "be digital" has never been greater, but you can meet the challenge. The digital revolution is here, changing how work gets done, how industries are structured, and how people from all walks of life work, behave, and relate to each other. To thrive... View Details

Keywords: Digital; Artificial Intelligence; Big Data; Digital Transformation; Technological Innovation; Transformation; Learning; Competency and Skills

April 2022
Supplement

Mastercard Labs (B)

By: Linda A. Hill, Sunil Gupta, Emily Tedards and Julia Kelley

When Ajaypal (Ajay) Banga became the CEO of Mastercard in 2010, digital technologies were on the rise, and innovation needed to become a strategic imperative at the company. Banga tasked Garry Lyons, who had joined Mastercard through the 2009 acquisition of Orbiscom,... View Details

April 2022
Case

Mastercard: Creating a World Beyond Cash

By: Sunil Gupta, Linda A. Hill, Julia Kelley and Emily Tedards

In late 2021, Mastercard CEO Michael Miebach and Chairman and former CEO Ajaypal “Ajay” Banga considered how Mastercard could best position itself for continued success in the years to come. Since Mastercard’s initial public offering in 2006, the company had grown and... View Details

April 2022
Teaching Note

CVS Health: Prescription for Transformation

By: Rosabeth Moss Kanter and Catarina Martinez

In 2021, new CEO Karen Lynch (named the most powerful woman in business) considered the next transformation phase for CVS Health (a Fortune 5 corporate giant). The 2018 acquisition of Aetna insurance brought her to the company as part of its long evolution from a... View Details

Keywords: Health; COVID-19 Pandemic; Primary Care; Leadership; Change Management; Women Executives; Retail; Pharmacy; Pharmacy Benefit Manager; Clinical Trials; Vaccination; Acquisition; Innovation and Invention; Transformation; Retail Industry; Pharmaceutical Industry; Health Industry; United States

24 Feb 2022
Other Presentation

The Fearless ICU

By: Amy C. Edmondson

The last 24 months have pushed ICU teams around the world to their limits. As we move forward, we need to heal and rebuild our critical care teams. Healthcare more than ever will require ICU teams to perform at the highest levels and to continuously innovate to deliver... View Details

Keywords: Psychological Safety; Teams; Critical Care; Health Care and Treatment; Groups and Teams; Performance Effectiveness

February 2022 (Revised April 2022)
Case

CVS Health: Prescription for Transformation

By: Rosabeth Moss Kanter and Tuna Cem Hayirli

In 2021, new CEO Karen Lynch (named the most powerful woman in business) considered the next transformation phase for CVS Health (a Fortune 5 corporate giant. The 2018 acquisition of Aetna insurance brought her to the company as part of its long evolution from a... View Details

Keywords: COVID; Caregiving; Healthcare; Access; Change; Retail; Health; Health Care and Treatment; Organizational Change and Adaptation; Transformation; Health Industry; Retail Industry

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