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  • September 2024
  • Case

Myeloma Investment Fund

By: Kyle Myers and Scott Sawaya
This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.

The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details
Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation & Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry
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Myers, Kyle, and Scott Sawaya. "Myeloma Investment Fund." Harvard Business School Case 625-047, September 2024.
  • September 2012 (Revised November 2014)
  • Case

Cialis Lifecycle Management: Lilly's BPH Dilemma

By: Elie Ofek and Natalie Kindred
How should Eli Lilly further develop and market a new indication of its highly successful erectile-dysfunction (ED) drug, Cialis, without confusing Cialis's hard-won brand equity with physicians and patients? With the final stages of clinical trials for the new... View Details
Keywords: Product Positioning; Attitudes; Brands and Branding; Pharmaceutical Industry; United States
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Ofek, Elie, and Natalie Kindred. "Cialis Lifecycle Management: Lilly's BPH Dilemma." Harvard Business School Case 513-005, September 2012. (Revised November 2014.)
  • Research Summary

Integrated Care for Total Knee Replacement: Quality of Life, Quality of Movement, User Acceptability

This study provides an opportunity to focus on the challenge of cross-organizational coordination in the healthcare setting. It is structured as a randomized clinical trial involving seven European hospitals (in seven different countries). It is focused specifically... View Details
  • 23 Apr 2007
  • Research & Ideas

Are Great Teams Less Productive?

be no role models. No other bike riders to observe and follow. In this case, learning is paving new ground, typically in a trial and error manner. In this process, performance... View Details
Keywords: by Sarah Jane Gilbert
  • 05 Oct 2010
  • First Look

First Look: October 5, 2010

  Working PapersTowards an Understanding of the Role of Standard Setters in Standard Setting Authors:Abigail Allen and Karthik Ramanna Abstract We investigate the idiosyncratic influence of standard setters in standard setting. In... View Details
Keywords: Sean Silverthorne
  • January 2023
  • Case

Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery

By: Regina Herzlinger and Brian Walker
What should a successful executive (HBS Baker Scholar) assess as her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to successfully commercialize Cleave Therapeutics’ drug for a cancer with no current successful... View Details
Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry
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Herzlinger, Regina, and Brian Walker. "Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery." Harvard Business School Case 323-045, January 2023.
  • March 2015
  • Case

Twine Health

By: Robert S. Huckman, Ariel D. Stern and Matthew G. Preble
In late 2014, Dr. John Moore (CEO), Frank Moss (chairman), and Scott Gilroy (CTO) of Twine Health (Twine) had to resolve several challenges that threatened to restrict the widespread dissemination of its sole product, Twine. Twine was a cloud-based platform that... View Details
Keywords: Health Care; Chronic Disease; Technology Adoption; Digital Health; Health Acceleration Challenge; Strategy; Disease Management; Health; Health Care and Treatment; Information Technology; Mobile and Wireless Technology; Health Industry; United States; Massachusetts
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Huckman, Robert S., Ariel D. Stern, and Matthew G. Preble. "Twine Health." Harvard Business School Case 615-068, March 2015.
  • June 2007
  • Article

Does Employment Protection Reduce Productivity? Evidence from U.S. States

By: David H Autor, William R. Kerr and Adriana D. Kugler
Theory predicts that mandated employment protections may reduce productivity by distorting production choices. Firms facing (non-Coasean) worker dismissal costs will curtail hiring below efficient levels and retain unproductive workers, both of which should affect... View Details
Keywords: Theory; Production; Selection and Staffing; Cost; Employment; Capital; Performance Productivity; United States
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Autor, David H., William R. Kerr, and Adriana D. Kugler. "Does Employment Protection Reduce Productivity? Evidence from U.S. States." Economic Journal 117, no. 521 (June 2007): 189–217.
  • September 2017
  • Supplement

Actera Group: Investing in Mars Cinema Group (A)

By: Victoria Ivashina and Eren Kuzucu
In summer of 2010, Murat Çavuşoğlu (HBS MBA 1994) led private equity firm Actera Group’s investment in Mars Cinema Group (Mars), the leading movie exhibitor in Turkey. Immediately after acquiring Mars and merging it with the second larger player in the market, AFM,... View Details
Keywords: Private Equity; Value Creation; Transformation; Valuation; Entertainment and Recreation Industry; Entertainment and Recreation Industry; Turkey
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Ivashina, Victoria, and Eren Kuzucu. "Actera Group: Investing in Mars Cinema Group (A)." Harvard Business School Spreadsheet Supplement 218-705, September 2017.
  • September 2017 (Revised July 2019)
  • Case

Actera Group: Investing in Mars Cinema Group (A)

By: Victoria Ivashina and Eren Kuzucu
In summer of 2010, Murat Çavuşoğlu (HBS MBA 1994) led private equity firm Actera Group’s investment in Mars Cinema Group (Mars), the leading movie exhibitor in Turkey. Immediately after acquiring Mars and merging it with the second largest player in the market, AFM,... View Details
Keywords: Private Equity; Value Creation; Transformation; Valuation; Entertainment and Recreation Industry; Entertainment and Recreation Industry; Turkey
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Ivashina, Victoria, and Eren Kuzucu. "Actera Group: Investing in Mars Cinema Group (A)." Harvard Business School Case 218-020, September 2017. (Revised July 2019.)
  • July 1998
  • Supplement

Bell Atlantic in Union City

By: Rosabeth M. Kanter
In this pioneering project to wire a school for the Internet and put computers in students' homes, Bell Atlantic combined its need for a beta site for a technology trial with the school reform efforts of the Union City, New Jersey public schools, under the leadership... View Details
Keywords: Business Model; Social Enterprise; Internet and the Web; Education; Business and Community Relations; Education Industry; New Jersey
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Kanter, Rosabeth M. "Bell Atlantic in Union City." Harvard Business School Video Supplement 399-501, July 1998.
  • 2022
  • Working Paper

Causal Inference During A Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina

By: Sebastian Calonico, Rafael Di Tella and Juan Cruz Lopez Del Valle
Many medical decisions during the pandemic were made without the support of causal evidence obtained in clinical trials. We study the case of nebulized ibuprofen (NaIHS), a drug that was extensively used on COVID-19 patients in Argentina amidst wild claims about its... View Details
Keywords: COVID-19; Drug Treatment; Health Pandemics; Health Care and Treatment; Decision Making; Outcome or Result; Argentina
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Calonico, Sebastian, Rafael Di Tella, and Juan Cruz Lopez Del Valle. "Causal Inference During A Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina." NBER Working Paper Series, No. 30084, May 2022.
  • April 2025 (Revised June 2025)
  • Case

Governing Sustainability in a Shifting Context (A)

By: Lynn S. Paine and Will Hurwitz
In early 2025, boards of directors had to rethink corporate responsibility and sustainability efforts amid rapidly-shifting social, legal, regulatory, and economic forces. While just a few years earlier, calls to address racial justice and climate change reached into... View Details
Keywords: Climate Change; Corporate Governance; Diversity; Leadership; Business or Company Management; Mission and Purpose; Social Media; Race; Environmental Sustainability; Governing Rules, Regulations, and Reforms; Governing and Advisory Boards; Lawfulness; Lawsuits and Litigation; Measurement and Metrics; Corporate Social Responsibility and Impact; Business and Shareholder Relations; Social Issues; Food and Beverage Industry; Food and Beverage Industry; Food and Beverage Industry; United States
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Paine, Lynn S., and Will Hurwitz. "Governing Sustainability in a Shifting Context (A)." Harvard Business School Case 325-121, April 2025. (Revised June 2025.)
  • March 2015
  • Case

Statoil: Transparency on Payments to Governments

By: George Serafeim
The Statoil case describes the challenge of increasing transparency, in extractive industries, around host county government payments. The case describes Statoil's reasoning behind voluntarily disclosing host country government payments, and the events that led to this... View Details
Keywords: Corruption; Disclosure; Disclosure Strategy; Regulation; Industry Self-regulation; Corporate Governance; Corporate Accountability; Bribery; Sustainability; Corporate Social Responsibility; Government Legislation; Cost vs Benefits; Corporate Disclosure; Mining; Mining Industry; United States
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Serafeim, George, Paul M. Healy, and Jérôme Lenhardt. "Statoil: Transparency on Payments to Governments." Harvard Business School Case 115-049, March 2015.
  • September 2020
  • Case

Disrupting Justice at RightNow: Persevere, Pivot or Perish

By: Shikhar Ghosh and Amir Reza Rezvani
The case examines the focus of an early stage company, and how an unexpected external incidence can threaten or void the business model. It encompasses issues such as defining and pivoting a business model, organizational requirements for a pivot, investor relations,... View Details
Keywords: Legal Aspects Of Business; Startup; Teams; Pivot; Financing; Entrepreneurship; Law; Venture Capital; Business Startups; Financing and Loans; Business Model; Organizational Change and Adaptation; Legal Services Industry; Germany
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Ghosh, Shikhar, and Amir Reza Rezvani. "Disrupting Justice at RightNow: Persevere, Pivot or Perish." Harvard Business School Case 821-027, September 2020.
  • 22 Dec 2015
  • First Look

December 22, 2015

Its Debt Debt Management Conflicts Between the U.S. Treasury and the Federal Reserve By: Greenwood, Robin, Samuel Gregory Hanson, Joshua S. Rudolph, and Lawrence Summers Abstract—No abstract available.... View Details
Keywords: Carmen Nobel
  • May 2020 (Revised July 2020)
  • Case

Justice-as-a-Service at RightNow

By: Shikhar Ghosh and Amir Reza Rezvani
The case examines the focus of an early stage company, and how an unexpected external incidence can threaten or void the business model. It encompasses issues such as minimal viable product, defining and pivoting a business model, organizational requirements for a... View Details
Keywords: Legacy Business; Teams; Startup; Business Models; Pivot; Entrepreneurship; Law; Venture Capital; Business Startups; Business Model; Organizational Change and Adaptation; Strategy; Legal Services Industry; Germany
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Ghosh, Shikhar, and Amir Reza Rezvani. "Justice-as-a-Service at RightNow." Harvard Business School Case 820-117, May 2020. (Revised July 2020.)
  • November 2018 (Revised October 2019)
  • Case

Rebuilding Puerto Rico

By: Laura Alfaro, Laura Phillips Sawyer and Haviland Sheldahl-Thomason
On September 20, 2017, Hurricane Maria swept over Puerto Rico, devastating the island’s infrastructure and agriculture. The natural disaster was layered atop years of mounting financial distress. Before the hurricane, Puerto Rico had accumulated $74 billion in debt and... View Details
Keywords: Natural Disasters; Financial Crisis; Infrastructure; Borrowing and Debt; Economy; Strategic Planning; Governing Rules, Regulations, and Reforms; Puerto Rico
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Alfaro, Laura, Laura Phillips Sawyer, and Haviland Sheldahl-Thomason. "Rebuilding Puerto Rico." Harvard Business School Case 719-018, November 2018. (Revised October 2019.)
  • February 2022
  • Case

Leading The UK Vaccine Task Force

By: Amy C. Edmondson and Claudia Pienica
This case describes the first six months of the UK Vaccine Taskforce, under the leadership of Kate Bingham. With a career spent in the private sector as a biotech investor, Bingham’s appointment within the government was considered unusual. The overarching brief given... View Details
Keywords: COVID-19; Vaccine; Government; Health Pandemics; Health Care and Treatment; Science; Innovation and Invention; Groups and Teams; Leadership; Decision Making; Government and Politics; Health; Innovation and Management; Governance; Change; Government Administration; Health Industry; Financial Services Industry; Public Administration Industry; Europe; United Kingdom
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Edmondson, Amy C., and Claudia Pienica. "Leading The UK Vaccine Task Force." Harvard Business School Case 622-079, February 2022.
  • December 2018
  • Case

Tiantong & Partners: Transforming Litigation Practice in China

By: Ashish Nanda and Lisa Rohrer
Jiang Yong founded Tiantong & Partners in 2002, seeking to radically improve the level of litigation-related services in China. By 2015, Tiantong was the premier Chinese litigation firm with the highest per lawyer revenues. The firm focused exclusively on high-stakes... View Details
Keywords: Law Firm; Law Firms; Growth; Legal Industry; Regulation; Professional Services; Law; Lawsuits and Litigation; Internet and the Web; Growth and Development; Strategy; Entrepreneurship; Decision Choices and Conditions; Legal Services Industry; China
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Nanda, Ashish, and Lisa Rohrer. "Tiantong & Partners: Transforming Litigation Practice in China." Harvard Business School Case 719-457, December 2018.
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