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  • All HBS Web  (11,801)
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  • September 2017 (Revised July 2023)
  • Case

Adaptive Platform Trials: The Clinical Trial of the Future?

By: Ariel D. Stern and Sarah Mehta
In July 2017, Dr. Brian M. Alexander, president and CEO of the AGILE Research Foundation, was preparing to launch a new type of clinical trial—an adaptive platform trial—to study potential therapies for glioblastoma (GBM), an aggressive form of brain cancer.... View Details
Keywords: Clinical Trials; Cancer; Adaptive Platform Trials; Platform Trials; Adaptive Trials; Glioblastoma; Health; Health Care and Treatment; Health Testing and Trials; Business Strategy; Innovation Strategy; Health Industry; United States
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Stern, Ariel D., and Sarah Mehta. "Adaptive Platform Trials: The Clinical Trial of the Future?" Harvard Business School Case 618-025, September 2017. (Revised July 2023.)
  • December 2003
  • Case

Sale of Hephaestus, Inc. to Vulcan Ventures, Inc.

Henry Hephaestus founded Hephaestus, Inc. in 1895. Its first product was a tapered roller bearing for use with horse-drawn wagons and carriages. It reduced friction on the axle and reduced the force necessary to move a heavy load, thereby enabling one horse to do the... View Details
Keywords: Business Exit or Shutdown; Entrepreneurship; Family Ownership; Manufacturing Industry
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Bagley, Constance E. "Sale of Hephaestus, Inc. to Vulcan Ventures, Inc." Harvard Business School Case 804-104, December 2003.
  • 30 Jun 2020
  • News

Disruption Amidst Disruption: Fintech in the Age of Coronavirus

  • February 2015
  • Teaching Note

Eataly: Reimagining the Grocery Store

By: Sunil Gupta and Michela Addis
Within a few years of its operations, the Italian-based supermarket Eataly created a lot of buzz and excitement among consumers and media. Eataly's initial success was even more impressive in an industry known for its intense competition and low margins. How did Eataly... View Details
Keywords: Customer Engagement; Innovation; Retailing; Supermarkets; Agribusiness; Entrepreneurship; Food; Customers; Innovation and Invention; Marketing; Retail Industry; Food and Beverage Industry; Europe; North and Central America; Asia
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Gupta, Sunil, and Michela Addis. "Eataly: Reimagining the Grocery Store." Harvard Business School Teaching Note 515-078, February 2015.
  • 2012
  • Working Paper

'Power from Sunshine': A Business History of Solar Energy

By: Geoffrey Jones and Loubna Bouamane
This working paper provides a longitudinal perspective on the business history of solar energy between the nineteenth century and the present day. It covers early attempts to develop solar energy, the use of passive solar in architecture before World War 2, and the... View Details
Keywords: Renewable Energy; Business History; Policy; Entrepreneurship; Innovation and Invention; Business Model; Energy Industry
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Jones, Geoffrey, and Loubna Bouamane. "'Power from Sunshine': A Business History of Solar Energy." Harvard Business School Working Paper, No. 12-105, May 2012.
  • 14 Jun 2010
  • Research & Ideas

The Hard Work of Measuring Social Impact

he says. "And obviously there should be a method for periodically testing and critiquing that strategy, and modifying it if it's not working." Ebrahim is working on a series of case studies focused on nonprofit and public organizations... View Details
Keywords: by Julia Hanna
  • October 2018
  • Case

Booking.com

By: Stefan Thomke and Daniela Beyersdorfer
The case reveals how Booking.com has become the world's leading travel accommodation platform. The company has put online experimentation at the heart of how it designs digital experiences for its customers and partners. To unlock the potential of large-scale testing,... View Details
Keywords: Travel; Product Innovation; Experimentation; A/B Testing; User Experience Design; Product Development; Product Design; Innovation and Management; Transformation; Information Technology; Digital Transformation; Travel Industry
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Thomke, Stefan, and Daniela Beyersdorfer. "Booking.com." Harvard Business School Case 619-015, October 2018.
  • Research Summary

Overview

Matthew's research examines how entrepreneurial organizations and their managers create social and institutional change. His latest project focuses on hybrid organizations that combine aspects of non-profits and companies to create innovative organizational forms. In... View Details
Keywords: Organization Theory; Hybrid Organizations; Entrepreneurship; Social Entrepreneurship; Corporate Social Responsibility; Innovation
  • 25 Mar 2010
  • Working Paper Summaries

Local R&D Strategies and Multi-location Firms: The Role of Internal Linkages

Keywords: by Juan Alcacer & Minyuan Zhao; Technology
  • 04 Mar 2024
  • Research & Ideas

Want to Make Diversity Stick? Break the Cycle of Sameness

progress on racial diversity or vice versa,” he says. Recognize that any progress is good progress. That is, when leaders take even small steps in the direction of diversity, they should keep in mind that... View Details
Keywords: by Michael Blanding
  • 01 Mar 2018
  • News

Excellence At The Intersection Of Disciplines

Across Harvard University, rapid innovation and technological change, among other factors, are prompting important collaborations that enhance learning and deepen understanding. Under the mantle of “One... View Details
  • 01 Dec 1997
  • News

A Piece of the Action

There is electricity in the air at 7:00 a.m. at Il Fornaio, Palo Alto's hottest breakfast spot. The cappuccino maker runs nonstop, the energetic waitstaff hustles to and from the kitchen, a steady stream of Silicon Valley celebs walk in... View Details
Keywords: Susan Young
  • Web

Conflict of Interest | About

Conflict of Interest HBS strives to adhere to the highest standard of integrity, ethics and respect in a manner consistent with HBS Community Standards. To view the staff policy, please refer to this page... View Details
  • August 2015 (Revised May 2017)
  • Case

TSG Hoffenheim: Football in the Age of Analytics

By: Feng Zhu, Karim R. Lakhani, Sascha L. Schmidt and Kerry Herman
In 2015, Dietmar Hopp, owner of Germany's Bundesliga football team TSG Hoffenheim and co-founder of the global enterprise software company SAP, was considering how to ensure long-term sustainability and competitiveness for TSG Hoffenheim. While historically a small... View Details
Keywords: Information Technology; Measurement and Metrics; Sports; Sports Industry
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Zhu, Feng, Karim R. Lakhani, Sascha L. Schmidt, and Kerry Herman. "TSG Hoffenheim: Football in the Age of Analytics." Harvard Business School Case 616-010, August 2015. (Revised May 2017.)
  • June 2013
  • Teaching Note

Rock Health

By: Robert Higgins and Ian McKown Cornell
This is the teaching note associated with HBS Case #813035. The case should enable students to identify emerging challenges, evaluate Rock Health's funding model, debate the effectiveness of its incubation service and assess its long-term viability. View Details
Keywords: Innovation; Incubation; Healthcare Technology; Startups; Entrepreneurship; Innovation and Management; Health Care and Treatment; Business Startups; Health Industry; San Francisco; California; United States
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Higgins, Robert, and Ian McKown Cornell. "Rock Health." Harvard Business School Teaching Note 813-136, June 2013.
  • January 2018
  • Article

The Central and Unacknowledged Role of the U.S. Food and Drug Administration in the Design and Execution of Medical Device Pivotal Trials

By: Aaron V. Kaplan and Ariel D. Stern
The introduction of new medical devices has transformed cardiovascular care in recent decades. Devices, such as heart valves, pacemakers, stents, ventricular assist devices, and implantable defibrillators, have prolonged and improved the quality of life for millions of... View Details
Keywords: Health Testing and Trials; Business and Government Relations; Governing Rules, Regulations, and Reforms; Information Publishing; Medical Devices and Supplies Industry; United States
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Kaplan, Aaron V., and Ariel D. Stern. "The Central and Unacknowledged Role of the U.S. Food and Drug Administration in the Design and Execution of Medical Device Pivotal Trials." JAMA Cardiology 3, no. 1 (January 2018): 5–6.
  • 01 Dec 2013
  • News

Joining Together for HBS

new HBS Fund Chairs, we are eager to explore how we can join together to help shape the future of HBS, ensuring that it continues to be a positive force in the world. We are excited about the School's View Details
Keywords: alumni giving; innovation; business education
  • 05 Mar 2008
  • Working Paper Summaries

Board of Directors’ Responsiveness to Shareholders: Evidence from Shareholder Proposals

Keywords: by Yonca Ertimur, Fabrizio Ferri & Stephen R. Stubben
  • 12 Apr 2022
  • Blog Post

The Many Languages of Medicine to Impact Care Delivery

Diversity Innovation Hub, a Mount Sinai venture addressing social and structural determinants of health in NYC. Recently, Ted was named an HBS Kaplan Fellow and RISE Fellow. While on my pediatrics rotation... View Details
  • 2013
  • Book

Manufacturing Morals: The Values of Silence in Business School Education

By: Michel Anteby

Corporate accountability is never far from the front page and Harvard Business School trains many future business leaders. But how does HBS formally and informally ensure its members embrace proper business standards? Relying on his faculty experience, Michel Anteby... View Details

Keywords: Ethics; Moral Sensibility; Business Education; Higher Education; Education; Education Industry; United States
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Anteby, Michel. Manufacturing Morals: The Values of Silence in Business School Education. University of Chicago Press, 2013.
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