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- April 2025
- Supplement
ZEISS: Commercializing Science
By: Maria P. Roche and Richie Zitomer
Spreadsheet Supplement for HBS Case No. 725-359. View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
- March 2025
- Case
Niramai: An AI Solution to Save Lives
By: Rembrand Koning, Maria P. Roche and Kairavi Dey
Founded in 2017, Niramai developed Thermalytix, a breast cancer screening tool. Thermalytix used a high-resolution thermal sensing device and machine learning algorithms to analyze thermal images and detect tumors. Its patented solution leveraged big data analytics,... View Details
- 2025
- Working Paper
Transferability MATTRs: Towards Understanding Antecedents of Strategic Licensing
By: Dafna F. Bearson and Maria P. Roche
This paper examines the antecedents of firms’ decisions to license intellectual property
(IP). We propose a conceptual framework emphasizing two critical factors: (1) transferability,
which we define as the ease of moving knowledge embodied in inventions across
firm... View Details
Bearson, Dafna F., and Maria P. Roche. "Transferability MATTRs: Towards Understanding Antecedents of Strategic Licensing." Harvard Business School Working Paper, No. 25-042, March 2025.
- March 2025
- Teaching Note
Moving Science: The Rowland Institute at Harvard
By: Maria P. Roche
Teaching Note for HBS Case No. 724-441. View Details
- January 2025
- Case
A Winning Strategy (A): Innovation in Olympic Speed Skating
By: Rebecca Karp, Maria Roche, Maisie Wiltshire-Gordon and Tom Quinn
This case describes two innovators in the Olympic sport of speed skating: the U.S. Men’s team, which devised a new approach to the team pursuit event following their disappointing performance in the 2018 Winter Olympics; and Nils van der Poel, a Swedish skater who... View Details
Keywords: Sports; Disruptive Innovation; Innovation Strategy; Competitive Strategy; Competitive Advantage; Knowledge Sharing; Sports Industry; United States; Sweden; Netherlands; Norway
Karp, Rebecca, Maria Roche, Maisie Wiltshire-Gordon, and Tom Quinn. "A Winning Strategy (A): Innovation in Olympic Speed Skating." Harvard Business School Case 725-391, January 2025.
- January 2025
- Supplement
A Winning Strategy (B): Innovation in Olympic Speed Skating
By: Rebecca Karp, Maria Roche, Maisie Wiltshire-Gordon and Tom Quinn
This case describes the aftermath of decisions made by two innovators in the Olympic sport of speed skating: the U.S. Men’s team, which devised a new approach to the team pursuit event; and Nils van der Poel, a Swedish skater who created a new training plan that defied... View Details
Keywords: Sports; Disruptive Innovation; Innovation Strategy; Competitive Strategy; Competitive Advantage; Knowledge Sharing; Performance Improvement; Sports Industry; United States; Sweden; Netherlands; Norway
Karp, Rebecca, Maria Roche, Maisie Wiltshire-Gordon, and Tom Quinn. "A Winning Strategy (B): Innovation in Olympic Speed Skating." Harvard Business School Supplement 725-413, January 2025.
- 2025
- Working Paper
Too Much, Too Soon? Early Funding, Technological Unconventionality, and Innovation Capabilities
By: Harsh Ketkar and Maria Roche
The availability of financial resources significantly shapes firm innovation outcomes, especially for early-stage,
innovation-focused technology firms. However, prior research has provided conflicting findings about this
relationship: On the one hand, resource... View Details
Keywords: Startups; Technology Strategy; Novelty; Unconventionality; Resource Constraints; Early Stage Firms; Business Startups; Technological Innovation; Entrepreneurial Finance
Ketkar, Harsh, and Maria Roche. "Too Much, Too Soon? Early Funding, Technological Unconventionality, and Innovation Capabilities." Harvard Business School Working Paper, No. 25-032, December 2024. (Revised February 2025.)
- July 2024
- Case
ZEISS: Commercializing Science
By: Maria P. Roche, Carlota Moniz and Daniela Beyersdorfer
Karl Lamprecht, President and CEO of the ZEISS AG Group, mused on how far ZEISS had come in 175 years of being a pioneer in optics, and how the course he had charted since taking the helm of the company could keep it on track. In his role, he oversaw the four core... View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
Roche, Maria P., Carlota Moniz, and Daniela Beyersdorfer. "ZEISS: Commercializing Science." Harvard Business School Case 725-359, July 2024.
- March 2024
- Teaching Note
CoPilot(s): Generative AI at Microsoft and GitHub
By: Frank Nagle and Maria P. Roche
This teaching note is the companion to case N9-624-010 CoPilot(s): Generative AI at Microsoft and GitHub, which takes place in late 2021. The case briefly describes the history of both GitHub and Microsoft with a particular focus on open source software (OSS)—software... View Details
- February 2024
- Teaching Note
The Globalization of Manchester City Football Group
By: Tiona Zuzul, Maria P. Roche and Exequiel Hernandez
Teaching Note for HBS Case No. 723-391. View Details
- February 2024 (Revised March 2025)
- Case
Moving Science: The Rowland Institute at Harvard
By: Maria P. Roche
Set in 2022, this case describes the considerations involved in organizing the physical relocation of the Rowland Institute at Harvard (RIH), a research institute established in 1980 by Edwin H. Land, the founder of the Polaroid Corporation, for the advancement of... View Details
Keywords: Optics; Engineering; Higher Education; Strategy; Science; Buildings and Facilities; Research and Development; Real Estate Industry; Biotechnology Industry
Roche, Maria P. "Moving Science: The Rowland Institute at Harvard." Harvard Business School Case 724-441, February 2024. (Revised March 2025.)
- 2023
- Working Paper
Coordinated R&D Programs and the Creation of New Industries
By: Daniel P. Gross and Maria P. Roche
Complex systems technologies—including “deep tech”—are prone to numerous frictions that stymie commercial development. Yet technologies with these features underpin some of the most valuable industries of the past century. We examine how large, mission-oriented... View Details
Keywords: Research and Development; Policy; Business and Government Relations; Technological Innovation; Collaborative Innovation and Invention
Gross, Daniel P., and Maria P. Roche. "Coordinated R&D Programs and the Creation of New Industries." Harvard Business School Working Paper, No. 24-027, April 2023. (Revised October 2024.)
- November 2023
- Case
Copilot(s): Generative AI at Microsoft and GitHub
This case tells the story of Microsoft’s 2018 acquisition of GitHub and the subsequent launch of GitHub Copilot, a tool that uses generative artificial intelligence to suggest snippets of code to software developers in real time. Set in late 2021, when Copilot was... View Details
Keywords: Business Ventures; Strategy; AI and Machine Learning; Applications and Software; Product Launch; Information Technology Industry; Technology Industry; Web Services Industry; United States; California
Nagle, Frank, Shane Greenstein, Maria P. Roche, Nataliya Langburd Wright, and Sarah Mehta. "Copilot(s): Generative AI at Microsoft and GitHub." Harvard Business School Case 624-010, November 2023.
- 2025
- Working Paper
Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance
By: Justine Boudou and Maria Roche
In this paper, we examine how a startup’s knowledge foundations—embedded in its
core technology—influence its performance in the exit market. Using a dataset of 1,006
biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1)
the degree of... View Details
Keywords: Firm Performance; Knowledge Foundations; Exits; Academic Startups; Inventor-founder; Specialized Scientific Knowledge; Competitive Advantage; Value Creation; Research; Information Publishing; Business Startups; Entrepreneurship
Boudou, Justine, and Maria Roche. "Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance." Harvard Business School Working Paper, No. 24-021, October 2023. (Revised February 2025.)
- September 2023 (Revised March 2025)
- Teaching Note
Accelerating AI Adoption in the U.S. Air Force
By: Maria P. Roche
Teaching Note for HBS Case No. 723-429. View Details
Keywords: AI; "USA,"; Military; Strategy; Innovation; Economic Growth; Organizational Design; Technology
- 2025
- Working Paper
Better Keep the Twenty Dollars: Incentivizing Innovation in Open Source
By: Annamaria Conti, Vansh Gupta, Jorge Guzman and Maria P. Roche
Open source is key to innovation yet is assumed to be done largely through intrinsic motivation. How can we incentivize it? In this paper, we examine the impact of a program providing monetary incentives to motivate innovators to contribute to open source. The Sponsors... View Details
Keywords: Open Source; Innovation; Incentives; Financial Rewards; Crowding Out; Open Source Distribution; Innovation and Invention; Motivation and Incentives; Technology Industry
Conti, Annamaria, Vansh Gupta, Jorge Guzman, and Maria P. Roche. "Better Keep the Twenty Dollars: Incentivizing Innovation in Open Source." Harvard Business School Working Paper, No. 24-014, September 2023. (Revised January 2025. NBER Working Paper Series, No. 31668, September 2023)
- 2023
- Working Paper
Learning to Use: Stack Overflow and Technology Adoption
By: Daniel Jay Brown and Maria P. Roche
In this paper, we examine the potential impact of Q&A websites on the adoption of technologies.
Using data from Stack Overflow – one of the most popular Q&A websites worldwide
– and implementing an instrumental-variable approach, we find that users whose questions... View Details
Brown, Daniel Jay, and Maria P. Roche. "Learning to Use: Stack Overflow and Technology Adoption." Harvard Business School Working Paper, No. 24-001, July 2023.
- March 2023 (Revised March 2025)
- Case
Accelerating AI Adoption in the U.S. Air Force
By: Maria P. Roche and Alexander Farrow
In August 2022, the Pentagon tasked U.S. Air Force Captain Victor Lopez to launch a new office for AFWERX, an Air Force innovation unit that leveraged commercial developers and military talent to acquire advanced technologies. This task was particularly arduous because... View Details
Keywords: Technological Innovation; Organizational Design; AI and Machine Learning; Adoption; Technology Adoption; United States
Roche, Maria P., and Alexander Farrow. "Accelerating AI Adoption in the U.S. Air Force." Harvard Business School Case 723-429, March 2023. (Revised March 2025.)
- March, 2023
- Article
Academic Entrepreneurship: Entrepreneurial Advisors and Their Advisees' Outcomes
By: Maria P. Roche
The transfer of complex knowledge and skills is difficult, often requiring intensive interaction and extensive periods of co-working between a mentor and mentee, which is particularly true in apprenticeship-like settings and on-the-job training. This paper studies a... View Details
Keywords: Entrepreneurship; Higher Education; Training; Personal Development and Career; Knowledge Dissemination
Roche, Maria P. "Academic Entrepreneurship: Entrepreneurial Advisors and Their Advisees' Outcomes." Organization Science 34, no. 2 (March, 2023): 959–986.
- December 2022 (Revised November 2023)
- Module Note
What Is the Game? Understanding the Environment
By: Maria P. Roche
As a strategist, one of your main tasks is to size up the external environment of your organization in its entirety. In this module, you will learn basic concepts and tools that will allow you to better understand the environment in which your organization operates. View Details
Roche, Maria P. "What Is the Game? Understanding the Environment." Harvard Business School Module Note 723-405, December 2022. (Revised November 2023.)