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Research Summary

The Business of Stem Cells

By: Debora L. Spar

In 2004, the topic of stem cell research made both medical and moral headlines. Buoyed by a series of technological breakthroughs, stem cell scientists grew increasingly convinced that they would eventually be able to use embryonic stem cells -- the pluripotent cells... View Details

January 2009 (Revised February 2009)
Case

Sydney IVF: Stem Cell Research

By: Robert L. Simons, Kathryn Rosenberg and Natalie Kindred

This case examines the strategy implementation and risk management decisions at Sydney IVF, a research-based in vitro fertilization and stem cell company based in Australia. Drs. Robert Jansen and Jock Anderson, who co-founded Sydney IVF in 1986, developed novel... View Details

Keywords: Ethics; Governing Rules, Regulations, and Reforms; Innovation and Management; Growth and Development Strategy; Risk Management; Genetics; Commercialization; Health Industry; Australia

November 2006 (Revised March 2008)
Case

The Harvard Stem Cell Institute

By: William A. Sahlman

Describes a set of issues confronting the leaders of the Harvard Stem Cell Institute, an innovative cross-university effort to accelerate scientific discovery and translation in the domain of stem cells. Covers a wide range of topics, including understanding how... View Details

Keywords: Talent and Talent Management; Higher Education; Entrepreneurship; Collaborative Innovation and Invention; Intellectual Property; Research and Development; Genetics; Biotechnology Industry; Health Industry; Massachusetts

June 2010 (Revised May 2017)
Teaching Note

Sydney IVF: Stem Cell Research

By: Robert Simons and Kathryn Rosenberg

Teaching Note for 109017. View Details

Keywords: Strategy And Execution; Management Control Systems; Levers Of Control; Strategy; Risk Management; Decisions; Cooperative Ownership; Product Development; Moral Sensibility; Governing Rules, Regulations, and Reforms; Expansion; Science-Based Business; Research; Management Practices and Processes; Business Subsidiaries; Biotechnology Industry; Sydney

2015
Report

The Global STEM Paradox

By: Mark R. Kramer, Kate Tallant, Amanda Oudin Goldberger and Flynn Lebus

Despite increasing numbers of science, technology, engineering, and math (STEM) graduates worldwide, STEM jobs remain unfilled in developed and developing countries. Through an exploration of the root causes of this global STEM paradox, FSG offers an answer to this... View Details

Keywords: STEM Labor; Science; Information Technology; Engineering; Jobs and Positions; Global Range

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January 2013
Supplement

Cabot Corporation: The Fuel Cell Decision (B)

By: Willy Shih and Ying Zhou

Managers at Cabot Corporation are faced with deciding the future of its fuel cell program. The (A) case recounts the view of the business manager and the technical project lead, and the (B) case describes the perspective of a senior manager who is the head of the New... View Details

January 2013
Case

Cabot Corporation: The Fuel Cell Decision (A)

By: Willy Shih and Ying Zhou

Managers at Cabot Corporation are faced with deciding the future of its fuel cell program. The (A) case recounts the view of the business manager and the technical project lead, and the (B) case describes the perspective of a senior manager who is the head of the New... View Details

2007
Article

Selling Stem Cell Science: How Markets Drive Law along the Technological Frontier

By: Debora Spar and Anna Harrington

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1977
Book

Cell Protein II

By: James E. Austin, Steven Tannenbaum and Daniel I. C. Wang

Keywords: Science

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June 2023
Article

How New Ideas Diffuse in Science

By: Mengjie Cheng, Daniel Scott Smith, Xiang Ren, Hancheng Cao, Sanne Smith and Daniel A. McFarland

What conditions help new ideas spread? Can knowledge entrepreneurs’ position and develop new ideas in ways that help them take off? Most innovation research focuses on products and their reference. That focus ignores the ideas themselves and the broader ideational... View Details

Keywords: Innovation Adoption; Natural Language Processing; Knowledge; Science; Innovation and Invention; Knowledge Sharing; Analytics and Data Science

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2016
Working Paper

Innovating in Science and Engineering or 'Cashing In' on Wall Street? Evidence on Elite STEM Talent

By: Pian Shu

Using data on MIT bachelor's graduates from 1994 to 2012, this paper empirically examines the extent to which the inflow of elite talent into the financial industry affects the supply of innovators in science and engineering (S&E). I first show that finance does not... View Details

Keywords: Higher Education; Engineering; Personal Development and Career; Science; Finance

26 Jul 2023
Research & Ideas

STEM Needs More Women. Recruiters Often Keep Them Out

For mid-career STEM professionals looking to advance their skills and careers, certificate programs at elite universities can offer a fast track. And for universities, such programs are an important and growing revenue stream—and a... View Details

Keywords: by Rachel Layne

2006
Book

Science Business: The Promise, the Reality, and the Future of Biotech

By: Gary P. Pisano

Why has the biotechnology industry failed to perform up to expectations—despite all its promise? In Science Business, Gary P. Pisano answers this question by providing an incisive critique of the industry. Pisano not only reveals the underlying causes of... View Details

Keywords: Science; Business Ventures; Biotechnology Industry

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March 2019
Case

Investing in the Future: Corning Inc. and the Alternative School for Math and Science

By: Derek van Bever and Miho Kubagawa

In early 2017, Kim Frock (MBA 1987), founder and administrative head of school for the Alternative School for Math and Science (ASMS) in Corning, New York, is beginning to think through the issue of leadership succession at the school. Founded in close partnership with... View Details

Keywords: Middle School Education; Leadership; Management Succession; Partners and Partnerships; Business and Community Relations

2018
Article

Insight into Gender Differences in STEM: Evidence from Peer Reviews in an Engineering Class

By: Jacqueline N. Lane, Bruce Ankenman and Seyed Iravani

As the service industry moves toward self-service, peer feedback serves a critical role in this shift for educational services. Peer feedback is a process by which students provide feedback to each other. One of its major benefits is that it enables students to become... View Details

Keywords: Peer Review; Peer Feedback; STEM Education; Anonymity; Education; Gender; Education Industry

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2025
Working Paper

Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance

By: Justine Boudou and Maria Roche

In this paper, we examine how a startup’s knowledge foundations—embedded in its core technology—influence its performance in the exit market. Using a dataset of 1,006 biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1) the degree of... View Details

Keywords: Firm Performance; Knowledge Foundations; Exits; Academic Startups; Inventor-founder; Specialized Scientific Knowledge; Competitive Advantage; Value Creation; Research; Information Publishing; Business Startups; Entrepreneurship

03 Jan 2017
Research & Ideas

5 New Year's Resolutions You Can Keep (With the Help of Behavioral Science Research)

discouraged them from making or increasing their own investments. In one instance, peer information reduced the likelihood of participation by more than a third. This discouragement, Beshears said, stemmed from employees being reminded... View Details

Keywords: by Carmen Nobel

January 2009 (Revised July 2010)
Case

iZumi

By: Robert F. Higgins, Jacob Ian Broder-Fingert, Eliot Sherman and Sidhartha Palani

Presents the issues faced while building an innovative company in an emerging space with new intellectual property from the perspective of a venture capitalist. Beth Seidenberg, a partner at the venture capital firm Kleiner Perkins Caufield & Byers (KPCB), had helped... View Details

Keywords: Entrepreneurship; Venture Capital; Globalized Markets and Industries; Innovation and Management; Intellectual Property; Rights; Genetics; Financial Services Industry; Health Industry

September 2020
Case

Minerva 2010: Turbulent Times

By: John R. Wells and Benjamin Weinstock

In 2010, amid a flurry of new discoveries, Cynthia Bamdad, founder and CEO of Minerva Biotechnologies Corporation (Minerva), raised $6.6 million to test her new cancer drugs in mice. It had been more than 6 years since she had announced that she and her small team at... View Details

Keywords: Biotechnology; Research; Product Development; Commercialization; Strategy

October 2018 (Revised August 2023)
Case

Safecast: Bootstrapping Human Capital to Big Data

By: Ethan Bernstein and Stephanie Marton

On March 11, 2011, at 2:46pm, a 9.1-on-the-Richter-scale, six-minute long earthquake unleashed a tsunami that ravaged the Tohoku region of Japan, damaging the Fukushima Daiichi Nuclear Power facility and releasing sufficient radioactive material into the air and ocean... View Details

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