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- October 2024
- Case
Parexel: Scaling Up and Industry Dynamics
By: Regina E. Herzlinger and Ben Creo
Through the lens of biopharmaceutical contract research organization (CRO) PAREXEL, this case traces the evolution of the firm as it reinvents itself in response to the transformation of the CRO sector from a small, secondary cluster of firms into a major player with... View Details
- 2024
- Working Paper
Public Sector SME Grading System in Emerging Markets: A Focus on Nigeria
By: Saveshen Pillay, Anywhere Sikochi, Charles Odii, Zaakirah Ismail, Regina Bamaiyi and Denise Mubaiwa
In this paper, we explore the impact of creating a public sector nano, micro, small and medium
enterprise (nMSME) grading system in Nigeria. Using insights from work with the Nigerian
government, the first country in Africa to attempt to establish a public sector SME... View Details
Pillay, Saveshen, Anywhere Sikochi, Charles Odii, Zaakirah Ismail, Regina Bamaiyi, and Denise Mubaiwa. "Public Sector SME Grading System in Emerging Markets: A Focus on Nigeria." Working Paper, October 2024.
- September 2024
- Case
Epic: The Future of Health Information Technology
By: Regina E. Herzlinger and Brian L. Walker
- August 2024
- Background Note
The Five Pillars That Drive the Success or Failure of Healthcare and Life Sciences Innovations
- May 2, 2024
- Article
Require Hospitals to Disclose Their Pandemic Plans Now
By: Regina E. Herzlinger, Richard J. Boxer and Ben Creo
The COVID-19 pandemic demonstrated that U.S. hospital and health care systems were ill-prepared for the surge of patients who overwhelmed available health care resources. An overlooked resource deserves more attention: the availability of intensive care unit (ICU)... View Details
Keywords: COVID-19 Pandemic; Crisis Management; Knowledge Sharing; Governance Compliance; Planning; Health Industry; United States
Herzlinger, Regina E., Richard J. Boxer, and Ben Creo. "Require Hospitals to Disclose Their Pandemic Plans Now." Health Affairs Forefront (May 2, 2024).
- 18 Apr 2024
- Lecture
Innovation Opportunities Created by COVID-19 Can Help: And How to Make Them Happen
The crush of patients created by COVID enabled the creation of sites for care outside the traditional hospital, such as retail pharmacies, ambulatory surgery centers, urgent care centers, telemedicine, and wireless sensors. Public policy mirrored these changes by... View Details
- January 2024
- Background Note
Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?
By: Regina E. Herzlinger and James Wallace
How can we evaluate if innovative health care ventures can do good—benefit society—and do well—become financially viable? This question is the topic of the first module in the Innovating in Health Care course book.
This note and "Health Stop (A): What Type... View Details
This note and "Health Stop (A): What Type... View Details
- December 2023
- Article
Association of Hospital System Affiliation with COVID-19 Capacity Burden
By: Zachary Levin, Pinar Karaca-Mandic, Richard J. Boxer and Regina E. Herzlinger
What is the message? The COVID-19 pandemic exposed the highly variable and uncoordinated responses by hospitals. The authors found that while the non-top ten system affiliated hospitals had a larger COVID-19 share index relative to independent hospitals, top-ten system... View Details
Keywords: COVID-19 Pandemic; Resource Allocation; Health Pandemics; Demographics; Health Care and Treatment; Health Industry
Levin, Zachary, Pinar Karaca-Mandic, Richard J. Boxer, and Regina E. Herzlinger. "Association of Hospital System Affiliation with COVID-19 Capacity Burden." Health Management, Policy and Innovation 8, no. 3 (December 2023).
- September 2023
- Supplement
Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment
This PowerPoint accompanies Regina E. Herzlinger's "Fighting the Battle of the Bulge – Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment" teaching note (HBS Case No.324-013) and is designed for instructors to use in the classroom when teaching this... View Details
- September 2023
- Teaching Note
Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment
Teaching Note for HBS Case No. 304-009. The case is part of the first module of the Innovating in Health Care course. Its purpose is to demonstrate how to evaluate the “do good” and do well” potential of a health care innovation. View Details
- 3 Jun 2023
- Talk
Health Care Innovation Opportunities Created by COVID-19 and How to Make Them Happen
The crush of patients created by COVID enabled the creation of sites for care outside the traditional hospital, such as retail pharmacies, ambulatory surgery centers, urgent care centers, telemedicine, and wireless sensors. Public policy mirrored these changes by... View Details
Keywords: Policy; Health Pandemics; Health Care and Treatment; Innovation and Invention; Health Industry; Insurance Industry
Herzlinger, Regina E. "Health Care Innovation Opportunities Created by COVID-19 and How to Make Them Happen." Harvard Business School Alumni Reunion, Boston, MA, June 3, 2023. (Link to cases described in this talk.)
- April 2023 (Revised January 2024)
- Background Note
Note on Healthcare in Ghana
By: Regina E. Herzlinger and Ben Creo
This note provides an overview of the healthcare system in Ghana. It discusses the public and private sector as well as traditional medical practice. It also discusses the country’s pharmaceutical industry. It is recommended as a companion to Professor Regina... View Details
Keywords: Africa; Pharmaceutical Companies; Pharmacy Benefit Manager; Health Care; Health Care Costs; Health Care Delivery; Health Care Entrepreneurship; Telehealth; Health Equity; Governing Rules, Regulations, and Reforms; Health Care and Treatment; Business and Government Relations; Health Industry; Pharmaceutical Industry; Ghana
Herzlinger, Regina E., and Ben Creo. "Note on Healthcare in Ghana." Harvard Business School Background Note 323-112, April 2023. (Revised January 2024.)
- April 24, 2023
- Article
In the COVID Era, Why Corporate Benefits Demand CEO/CFO Leadership
The expectation that employers provide their employees’ health benefits has been around since World War II. Unfortunately, although today’s employees expect employers to treat them as individuals, ease their experiences, prioritize their wellbeing, and control cost,... View Details
Keywords: COVID; COVID-19 Pandemic; CEO; Leadership; Health Insurance; Benefits; CFO; Compensation and Benefits
Herzlinger, Regina E. "In the COVID Era, Why Corporate Benefits Demand CEO/CFO Leadership." CMR Insights (April 24, 2023).
- January 2023
- Teaching Note
Identify the Health Care Venture
By: Regina E. Herzlinger and James Wallace
Teaching Note for HBS Exercise No. 323-061. View Details
- January 2023
- Exercise
Identify the Health Care Venture
By: Regina E. Herzlinger and James Wallace
This case enables rapid learning of the key financial characteristics of many types of health care organizations and to diagnose their financial status. It is a surprisingly fun exercise (see the Teaching Note) accomplished by organizing groups of students that compete... View Details
Keywords: Health Care; Health Care Spending; Health Care Financing; Health Care Industry; Health Care Operations; Health Care Delivery; Health Care and Treatment; Financial Condition; Health Industry
Herzlinger, Regina E., and James Wallace. "Identify the Health Care Venture." Harvard Business School Exercise 323-061, January 2023.
- January 2023
- Case
Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery
By: Regina Herzlinger and Brian Walker
What should a successful executive (HBS Baker Scholar) assess as her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to successfully commercialize Cleave Therapeutics’ drug for a cancer with no current successful... View Details
Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry
Herzlinger, Regina, and Brian Walker. "Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery." Harvard Business School Case 323-045, January 2023.
- December 2022 (Revised September 2024)
- Case
Sword Health
By: Regina E. Herzlinger, Annelena Lobb and Carin-Isabel Knoop
Virgilio “V” Bento, CEO of Sword Health—a startup that provided virtual physical therapy to patients in self-insured firms via AI and sensor technology with supervision by a physical therapist with a doctorate—considered how to increase its U.S. market share. To do so,... View Details
Keywords: Business Growth and Maturation; Competitive Strategy; Health Industry; Technology Industry
Herzlinger, Regina E., Annelena Lobb, and Carin-Isabel Knoop. "Sword Health." Harvard Business School Case 323-022, December 2022. (Revised September 2024.)
- November 2022
- Case
Ajax Health: A New Model for Medical Technology Innovation
By: Regina E. Herzlinger and Ben Creo
This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets... View Details
Keywords: Business Startups; Success; Innovation Strategy; Mergers and Acquisitions; Market Entry and Exit; Financial Strategy; Business Model; Partners and Partnerships; Entrepreneurship; Private Equity; Technology Industry; Medical Devices and Supplies Industry
Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
- November 2022
- Case
The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales
By: Regina E. Herzlinger and Tiffany Farrell
Can an online, direct-to-consumer pharmacy both improve the quality and speed of care for patients who need branded drugs and stabilize profits for pharmaceutical manufacturers? UpScript, after years spent achieving legal and regulatory compliance and simultaneous... View Details
Keywords: DTC; Internet and the Web; Marketing Channels; Customer Value and Value Chain; Governing Rules, Regulations, and Reforms; Competitive Strategy; Service Delivery; Growth and Development Strategy; Pharmaceutical Industry; Health Industry; Retail Industry
Herzlinger, Regina E., and Tiffany Farrell. "The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales." Harvard Business School Case 323-031, November 2022.
- November 1, 2022
- Article
To Prepare for Future Surges, U.S. Hospitals Must Start Planning—& Sharing Resources—Now!
Keywords: COVID-19; Crisis Management; Health Pandemics; Disruption; Planning; Health Industry; United States
Herzlinger, Regina E. "To Prepare for Future Surges, U.S. Hospitals Must Start Planning—& Sharing Resources—Now!" Medical Device News Magazine (November 1, 2022).