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- All HBS Web
(143)
- News (61)
- Research (35)
- Events (4)
- Multimedia (4)
- Faculty Publications (26)
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- August 2019
- Case
Synthetic Biology Investment Opportunity
By: Peter Barrett, Karim R. Lakhani, Julia Kelley and Kerry Herman
Using an overview of the emerging technology of Synthetic Biology, this case provides the basis for discussion on what questions one would ask in evaluating a potential investment in the field. View Details
Barrett, Peter, Karim R. Lakhani, Julia Kelley, and Kerry Herman. "Synthetic Biology Investment Opportunity." Harvard Business School Case 620-015, August 2019.
- Article
Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions
By: Andrea Blasco, Michael G. Endres, Rinat A. Sergeev, Anup Jonchhe, Max Macaluso, Rajiv Narayan, Ted Natoli, Jin H. Paik, Bryan Briney, Chunlei Wu, Andrew I. Su, Aravind Subramanian and Karim R. Lakhani
Open data science and algorithm development competitions offer a unique avenue for rapid discovery of better computational strategies. We highlight three examples in computational biology and bioinformatics research where the use of competitions has yielded significant... View Details
Keywords: Computational Biology; Bioinformatics; Innovation Competitions; Research; Collaborative Innovation and Invention
Blasco, Andrea, Michael G. Endres, Rinat A. Sergeev, Anup Jonchhe, Max Macaluso, Rajiv Narayan, Ted Natoli, Jin H. Paik, Bryan Briney, Chunlei Wu, Andrew I. Su, Aravind Subramanian, and Karim R. Lakhani. "Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions." PLoS ONE 14, no. 9 (September 2019).
- Awards
Synthetic Biology 3.0 Travel Fellowship
Received a 2007 Synthetic Biology 3.0 Travel Fellowship to present at Synthetic Biology 3.0 in Zurich, Switzerland. View Details
- 01 Sep 2008
- News
Social Intelligence and the Biology of Leadership
Keywords: Daniel Goleman and Richard Boyatzis
- 18 Sep 2020
- HBS Seminar
Megan Frederickson, University of Toronto, Ecology & Evolutionary Biology
- December 2009
- Article
Aspects of the Political Economy of Development and Synthetic Biology
By: Rachel Wellhausen and Gautam Mukunda
Wellhausen, Rachel, and Gautam Mukunda. "Aspects of the Political Economy of Development and Synthetic Biology." Systems and Synthetic Biology 3, nos. 1-4 (December 2009): 115–123.
- Oct 2008
- Conference Presentation
The Rumpelstiltskin Effect: Synthetic Biology and International Trade
By: Gautam Mukunda and Rachel Wellhausen
- 15 Jun 2011 - 17 Jun 2011
- Conference Presentation
A multi-disciplinary process for assessing synthetic biology applications
By: Gautam Mukunda, Allen Lin and Kenneth Oye
Keywords: Science
- Other Article
Prize-based Contests Can Provide Solutions to Computational Biology Problems
By: Karim R. Lakhani, Kevin J. Boudreau, Po-Ru Loh, Lars Backstrom, Carliss Y. Baldwin, Eric Lonstein, Mike Lydon, Alan MacCormack, Ramy A. Arnaout and Eva C. Guinan
Lakhani, Karim R., Kevin J. Boudreau, Po-Ru Loh, Lars Backstrom, Carliss Y. Baldwin, Eric Lonstein, Mike Lydon, Alan MacCormack, Ramy A. Arnaout, and Eva C. Guinan. "Prize-based Contests Can Provide Solutions to Computational Biology Problems." Nature Biotechnology 31, no. 2 (February 2013): 108–111.
- 21 Mar 2019
- Working Paper Summaries
Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions
- September 15, 2021
- Article
Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map
By: Andrea Blasco, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani and Aravind Subramanian
A recurring problem in biomedical research is how to isolate signals of distinct populations (cell types, tissues, and genes) from composite measures obtained by a single analyte or sensor. Existing computational deconvolution approaches work well in many specific... View Details
Keywords: Deconvolution; Methods; Open Innovation Competition; Genomics; Research; Innovation and Invention
Blasco, Andrea, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani, and Aravind Subramanian. "Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map." Bioinformatics 37, no. 18 (September 15, 2021).
- 01 Sep 2007
- News
Stem Cell Man
Last year, Brock Reeve (MBA ’88) was named executive director of the Harvard Stem Cell Institute to bring his managerial and diplomatic skills to bear on achieving organizational cohesion and help speed laboratory innovations to market. “Although not a scientist... View Details
- 20 Jun 2019
- Blog Post
What is the MS/MBA Biotechnology: Life Sciences Program? A Q&A with Bill Anderson, Senior Lecturer on Stem Cell and Regenerative Biology
train a cadre of leaders prepared to deal with the broadest issues at the interface of biology and society. In the curriculum, there will be a particular emphasis on medical problems in currently underserved populations, as part of... View Details
- February 2015
- Article
'Open' Disclosure of Innovations, Incentives and Follow-on Reuse: Theory on Processes of Cumulative Innovation and a Field Experiment in Computational Biology
By: Kevin J. Boudreau and Karim R. Lakhani
Most of society's innovation systems―academic science, the patent system, open source, etc.―are "open" in the sense that they are designed to facilitate knowledge disclosure among innovators. An essential difference across innovation systems is whether disclosure is of... View Details
Keywords: Open Innovation; Cumulative Innovation; Incentives; Search; Disclosure And Access; Knowledge Sharing; Motivation and Incentives; Collaborative Innovation and Invention
Boudreau, Kevin J., and Karim R. Lakhani. "'Open' Disclosure of Innovations, Incentives and Follow-on Reuse: Theory on Processes of Cumulative Innovation and a Field Experiment in Computational Biology." Research Policy 44, no. 1 (February 2015): 4–19.
- 03 Dec 2001
- Research & Ideas
Healthcare Conference Looks At Ailing Industry
Genomic Research. Even the impetus for common diseases such as diabetes and hypertension continues to elude scientists, he said. Eric S. Lander But that will change. The major achievement that underlies biology and medicine today is that... View Details
- October 2022 (Revised May 2023)
- Case
Ginkgo Bioworks vs. Scorpion Capital: The Debate Over Related-Party Revenues
Ginkgo Bioworks, a synthetic biology company based in Boston, Massachusetts, faced divergent views on its revenue possibilities and accounting practices. After a report emerged accusing it of fraudulent accounting and lack of innovation, its share price plunged. But... View Details
Keywords: Fraud Allegations; Revenue; Reports; Accounting Audits; Innovation and Management; Investment; Biotechnology Industry; Boston
Dey, Aiyesha, Jonas Heese, Suraj Srinivasan, and Annelena Lobb. "Ginkgo Bioworks vs. Scorpion Capital: The Debate Over Related-Party Revenues." Harvard Business School Case 123-037, October 2022. (Revised May 2023.)
- 12 Apr 2022
- Blog Post
The Many Languages of Medicine to Impact Care Delivery
stories, and partnering with them to help them meet their health goals. Being in the clinic was a great opportunity for me to apply what I previously learned in real-time to help a real patient. Unexpectedly, spending time with patients re-focused my interest back to... View Details