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      • January 2025
      • Technical Note

      AI vs Human: Analyzing Acceptable Error Rates Using the Confusion Matrix

      By: Tsedal Neeley and Tim Englehart
      This technical note introduces the confusion matrix as a foundational tool in artificial intelligence (AI) and large language models (LLMs) for assessing the performance of classification models, focusing on their reliability for decision-making. A confusion matrix... View Details
      Keywords: Reliability; Confusion Matrix; AI and Machine Learning; Decision Making; Measurement and Metrics; Performance
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      Neeley, Tsedal, and Tim Englehart. "AI vs Human: Analyzing Acceptable Error Rates Using the Confusion Matrix." Harvard Business School Technical Note 425-049, January 2025.
      • 2025
      • Working Paper

      Crossing the Design-Use Divide: How Process Manipulation Shapes the Design and Use of AI

      By: Rebecca Karp
      Existing literature often separates research on the design of innovations from their implementation and use, neglecting the role of selection—how organizations choose which innovations to implement. Although scholars suggest scientific approaches for selecting novel... View Details
      Keywords: Decision Choices and Conditions; Technology Adoption; Groups and Teams; Prejudice and Bias
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      Karp, Rebecca. "Crossing the Design-Use Divide: How Process Manipulation Shapes the Design and Use of AI." Harvard Business School Working Paper, No. 25-034, January 2025.
      • January 2025
      • Case

      A Tiger in the Tank: Exxon Sues Investors

      By: Clayton S. Rose, Sarah Sasso and James Weber
      In June 2024, investors were trying to make sense of ExxonMobil’s (Exxon) lawsuit against two impact investors, Arjuna Capital (Arjuna) and Follow This, that had just been dismissed by the U.S. District Court of Northern Texas. Exxon’s suit challenged the rights of two... View Details
      Keywords: Disruption; Talent and Talent Management; Customer Satisfaction; Decision Making; Demographics; Ethics; Corporate Accountability; Employees; Recruitment; Retention; Leadership; Crisis Management; Risk Management; Corporate Social Responsibility and Impact; Mission and Purpose; Organizational Change and Adaptation; Civil Society or Community; Social Issues; Adaptation; Investment Activism; Lawsuits and Litigation; Business and Shareholder Relations; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; United States; Netherlands; Norway
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      Rose, Clayton S., Sarah Sasso, and James Weber. "A Tiger in the Tank: Exxon Sues Investors." Harvard Business School Case 325-015, January 2025.
      • October 2024 (Revised February 2025)
      • Case

      Lanco Medical Group: Fostering Happiness for Growth

      By: Susanna Gallani, Jenyfeer Martínez Buitrago and Katherine Sonnefeldt
      This case describes how Lanco Medical Group, a fast-growing pharmaceutical distributor serving Latin America, approached the design of their employee benefits and incentives program. After learning about gaps between what leadership believed motivated employees and... View Details
      Keywords: Fairness; Compensation and Benefits; Retention; Growth Management; Motivation and Incentives; Expansion; Pharmaceutical Industry; Latin America
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      Gallani, Susanna, Jenyfeer Martínez Buitrago, and Katherine Sonnefeldt. "Lanco Medical Group: Fostering Happiness for Growth." Harvard Business School Case 125-062, October 2024. (Revised February 2025.)
      • September 2024
      • Case

      The Health Equity Accelerator at Boston Medical Center

      By: Susanna Gallani, Mary Witkowski and Katie Sonnefeldt
      This case describes how Boston Medical Center, a hospital and safety net organization, changed its strategic approach to health equity after realizing that previous efforts were not sufficient to address the health disparities among their patients. In 2021, the Health... View Details
      Keywords: Health Care and Treatment; Health Disorders; Innovation and Management; Innovation Leadership; Innovation Strategy; Adaptation; Business Strategy; Mission and Purpose; Decisions; Organizational Change and Adaptation; Organizational Structure; Diversity; Race; Ethnicity; Urban Scope; Local Range; Equality and Inequality; Health Industry; Boston
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      Gallani, Susanna, Mary Witkowski, and Katie Sonnefeldt. "The Health Equity Accelerator at Boston Medical Center." Harvard Business School Case 125-039, September 2024.
      • July 2024
      • Case

      ZEISS: Commercializing Science

      By: Maria P. Roche, Carlota Moniz and Daniela Beyersdorfer
      Karl Lamprecht, President and CEO of the ZEISS AG Group, mused on how far ZEISS had come in 175 years of being a pioneer in optics, and how the course he had charted since taking the helm of the company could keep it on track. In his role, he oversaw the four core... View Details
      Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
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      Roche, Maria P., Carlota Moniz, and Daniela Beyersdorfer. "ZEISS: Commercializing Science." Harvard Business School Case 725-359, July 2024.
      • May 2024
      • Case

      SofMedica Group: Managing Growth

      By: Boris Groysberg and Sarah L. Abbott
      SofMedica Group had expanded from its origins as a medical equipment distributor in Romania to a holding company with four business lines operating in six countries. This expansion had been driven by SofMedica’s mission: to make cutting edge medical technology... View Details
      Keywords: Growth; Healthcare Access; Healthcare; Medical Devices; Medical Equipment & Devices; Medical Care; Eastern Europe; Quality Management System; Health Care and Treatment; Growth Management; Education; Organizational Change and Adaptation; Quality; Leadership; Mission and Purpose; Expansion; Developing Countries and Economies; Technological Innovation; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Europe; Romania
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      Groysberg, Boris, and Sarah L. Abbott. "SofMedica Group: Managing Growth." Harvard Business School Case 424-027, May 2024.
      • April 2024
      • Article

      A Machine Learning Algorithm Predicting Risk of Dilating VUR among Infants with Hydronephrosis Using UTD Classification

      By: Hsin-Hsiao Scott Wang, Michael Lingzhi Li, Dylan Cahill, John Panagides, Tanya Logvinenko, Jeanne Chow and Caleb Nelson
      Backgrounds: Urinary Tract Dilation (UTD) classification has been designed to be a more objective grading system to evaluate antenatal and post-natal UTD. Due to unclear association between UTD classifications to specific anomalies such as vesico-ureteral reflux (VUR),... View Details
      Keywords: Health Disorders; Health Testing and Trials; AI and Machine Learning; Health Industry
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      Wang, Hsin-Hsiao Scott, Michael Lingzhi Li, Dylan Cahill, John Panagides, Tanya Logvinenko, Jeanne Chow, and Caleb Nelson. "A Machine Learning Algorithm Predicting Risk of Dilating VUR among Infants with Hydronephrosis Using UTD Classification." Journal of Pediatric Urology 20, no. 2 (April 2024): 271–278.
      • February 2024
      • Case

      More than Optics: Olympus's Vision to Become a Leading Global MedTech Company

      By: David J. Collis and Haisley Wert
      In August 2022, CEO Yasuo Takeuchi reflected on Olympus Corporation’s recent transformation from being known as a Japanese consumer camera company to becoming a leading global medical technology (MedTech) company. Over the past dozen years, Takeuchi and prior... View Details
      Keywords: Global Human Resource Management; Medical Technology; Corporate Strategy; Transformation; Globalization; Business Model; Leading Change; Organizational Structure; Organizational Change and Adaptation; Medical Devices and Supplies Industry; Japan; United States
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      Collis, David J., and Haisley Wert. "More than Optics: Olympus's Vision to Become a Leading Global MedTech Company." Harvard Business School Case 724-426, February 2024.
      • February 2024
      • Article

      Representation and Extrapolation: Evidence from Clinical Trials

      By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
      This article examines the consequences and causes of low enrollment of Black patients in clinical trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is more relevant for decision-making by physicians and patients when it... View Details
      Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry
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      Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." Quarterly Journal of Economics 139, no. 1 (February 2024): 575–635.
      • January 2024
      • Article

      A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder

      By: Sarah E. Wakeman, Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe and Robert S. Kaplan
      The US fee-for-service payment system under-reimburses clinics offering access to comprehensive treatments for opioid use disorder (OUD). The funding shortfall limits a clinic’s ability to expand and improve access, especially for socially marginalized patients with... View Details
      Keywords: Health Care and Treatment; Cost; Equality and Inequality; Health Industry
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      Wakeman, Sarah E., Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe, and Robert S. Kaplan. "A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder." Journal of Behavioral Health Services & Research 51, no. 1 (January 2024): 22–30.
      • 2023
      • Article

      Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset

      By: Junling Liu, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu and Michael Lingzhi Li
      Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address this gap, we introduce CMExam,... View Details
      Keywords: Large Language Model; AI and Machine Learning; Analytics and Data Science; Health Industry
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      Liu, Junling, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu, and Michael Lingzhi Li. "Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset." Conference on Neural Information Processing Systems (NeurIPS), Datasets and Benchmarks Track 36 (2023).
      • 2023
      • Book

      How the Harvard Business School Changed the Way We View Organizations

      By: Jay W. Lorsch
      The story of the field of organizational behavior (which overlaps considerably with the origin story of Harvard Business School) and how it created the “medical model” of systems thinking—anchored in the practices of listening, observing, testing, and only then... View Details
      Keywords: Organizational Behavior; Systems Thinking; Medical Model; Organizations; Behavior; System; History
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      Lorsch, Jay W. How the Harvard Business School Changed the Way We View Organizations. Business Expert Press, 2023.
      • April 2023 (Revised January 2024)
      • Background Note

      Note on Healthcare in Ghana

      By: Regina E. Herzlinger and Ben Creo
      This note provides an overview of the healthcare system in Ghana. It discusses the public and private sector as well as traditional medical practice. It also discusses the country’s pharmaceutical industry. It is recommended as a companion to Professor Regina... View Details
      Keywords: Africa; Pharmaceutical Companies; Pharmacy Benefit Manager; Health Care; Health Care Costs; Health Care Delivery; Health Care Entrepreneurship; Telehealth; Health Equity; Governing Rules, Regulations, and Reforms; Health Care and Treatment; Business and Government Relations; Health Industry; Pharmaceutical Industry; Ghana
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      Herzlinger, Regina E., and Ben Creo. "Note on Healthcare in Ghana." Harvard Business School Background Note 323-112, April 2023. (Revised January 2024.)
      • March 2023 (Revised March 2025)
      • Case

      Close Concerns: Diabetes Research and Advocacy

      By: Regina Herzlinger and Brian L. Walker
      Diagnosed with diabetes at the age of 18, Kelly Close understood the importance of balancing consistency and iteration. This principle had also informed her professional work, which started with a rapid promotion from financial analyst at Goldman Sachs to an analyst... View Details
      Keywords: Diabetes; Health; Health Care; Health Care And Treatment; Health Care Outcomes; Health Care Industry; Knowledge Dissemination; Outcome or Result; Equality and Inequality; Business Model; Entrepreneurship
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      Herzlinger, Regina, and Brian L. Walker. "Close Concerns: Diabetes Research and Advocacy." Harvard Business School Case 323-047, March 2023. (Revised March 2025.)
      • March 2023 (Revised June 2023)
      • Teaching Note

      Ransomware Attack at Springhill Medical Center

      By: Suraj Srinivasan and Li-Kuan (Jason) Ni
      Teaching Note for HBS Case No. 123-065. In July, 2019, Springhill Medical Center (“SMC”) in Mobile, Alabama fell prey to a malicious ransomware attack that crippled the hospital’s internal network systems and public-facing web page. While the hospital rushed to... View Details
      Keywords: Disruption; Communication; Communication Strategy; Decision Making; Decision Choices and Conditions; Judgments; Corporate Accountability; Corporate Disclosure; Corporate Governance; Governance Controls; Policy; Employees; News; Cybersecurity; Digital Strategy; Information Infrastructure; Information Management; Internet and the Web; Crisis Management; Business or Company Management; Resource Allocation; Risk Management; Negotiation Tactics; Failure; Business and Stakeholder Relations; Attitudes; Behavior; Perception; Reputation; Trust; Public Opinion; Social Issues; Health Industry; Alabama; United States
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      Srinivasan, Suraj, and Li-Kuan (Jason) Ni. "Ransomware Attack at Springhill Medical Center." Harvard Business School Teaching Note 123-068, March 2023. (Revised June 2023.)
      • February 2023
      • Case

      Ransomware Attack at Springhill Medical Center

      By: Suraj Srinivasan and Li-Kuan (Jason) Ni
      In July, 2019, Springhill Medical Center (“SMC”) in Mobile, Alabama, fell prey to a malicious ransomware attack that crippled the hospital’s internal network systems and public-facing web page. While the hospital rushed to securely restore the network, medical... View Details
      Keywords: Disruption; Communication; Communication Strategy; Decision Making; Decision Choices and Conditions; Judgments; Corporate Accountability; Corporate Disclosure; Corporate Governance; Governance Controls; Policy; Employees; News; Cybersecurity; Digital Strategy; Information Infrastructure; Information Management; Internet and the Web; Crisis Management; Resource Allocation; Risk Management; Negotiation Tactics; Failure; Business and Stakeholder Relations; Attitudes; Behavior; Perception; Reputation; Trust; Public Opinion; Social Issues; Health Industry; United States; Alabama
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      Srinivasan, Suraj, and Li-Kuan (Jason) Ni. "Ransomware Attack at Springhill Medical Center." Harvard Business School Case 123-065, February 2023.
      • September 2022
      • Case

      HPP: Tapping the Netherlands’ Potential

      By: Brian Trelstad and Idelès Kaandorp
      Stichting Het Potentieel Pakken (HPP) was launched to solve a systemic problem in the Dutch Labor Market: gender inequity that was leading to a large number of women to work part-time in fields that were in desperately short supply of labor, like health care, child... View Details
      Keywords: COVID-19 Pandemic; Grants; Scaling And Growth; Nonprofit Organizations; Opportunities; Gender; Income; Employment; Health Care and Treatment; Human Capital; Mission and Purpose; Motivation and Incentives; Growth and Development Strategy; Employment Industry; Health Industry; Education Industry; Consulting Industry; Europe; Netherlands
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      Trelstad, Brian, and Idelès Kaandorp. "HPP: Tapping the Netherlands’ Potential." Harvard Business School Case 323-024, September 2022.
      • June 2022
      • Teaching Plan

      Lifebank Nigeria

      By: Brian Trelstad, Pippa Tubman Armerding and Wale Lawal
      The aspiration of addressing maternal deaths in Nigeria, which were mostly caused by blood shortages, led Temie Giwa-Tubosun to found LifeBank in 2015. LifeBank developed an online platform that enabled hospitals to connect and purchase blood from local blood banks and... View Details
      Keywords: Systems Design; Social Business; Business At The Base Of The Pyramid; Health Care; Blood; Social Enterprise; Health Care and Treatment; Growth and Development Strategy; Finance; Health Industry; Transportation Industry; Africa; Nigeria
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      Trelstad, Brian, Pippa Tubman Armerding, and Wale Lawal. "Lifebank Nigeria." Harvard Business School Teaching Plan 322-090, June 2022.
      • Article

      A Career Life-Cycle Perspective on Women's Health and Safety

      By: Robert S. Kaplan, Chizoba L. Chukwura, Gregory H. Gorman, Vivian S. Lee, Chester B. Good, Kathleen L. Martin, Gregory A. Ator and Michael D. Parkinson
      Women's health has demanded more attention from employers as women integrated into the workforce. Traditionally male-dominant fields and occupations require special attention to workplace design, physical standards for entry, employment practices, equipment, and health... View Details
      Keywords: Women's Health; Healthcare Access; Workplace Design; Military Health System; Occupational Health; Medical Equipment & Devices; Employees; Gender; Personal Development and Career
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      Kaplan, Robert S., Chizoba L. Chukwura, Gregory H. Gorman, Vivian S. Lee, Chester B. Good, Kathleen L. Martin, Gregory A. Ator, and Michael D. Parkinson. "A Career Life-Cycle Perspective on Women's Health and Safety." Journal of Occupational and Environmental Medicine 64, no. 4 (April 2022): 267–270.
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