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- February 2025
- Article
Variation in Batch Ordering of Imaging Tests in the Emergency Department and the Impact on Care Delivery
By: Jacob C. Jameson, Soroush Saghafian, Robert S. Huckman and Nicole Hodgson
Objectives: To examine heterogeneity in physician batch ordering practices and measure the impact of a physician's tendency to batch order imaging tests on patient outcomes and resource utilization.
Study Setting and Design: In this retrospective study, we used... View Details
Study Setting and Design: In this retrospective study, we used... View Details
Keywords: Health Care; Operations Management; Productivity; Health Care and Treatment; Operations; Outcome or Result; Resource Allocation; Health Industry; United States
Jameson, Jacob C., Soroush Saghafian, Robert S. Huckman, and Nicole Hodgson. "Variation in Batch Ordering of Imaging Tests in the Emergency Department and the Impact on Care Delivery." Health Services Research 60, no. 1 (February 2025).
- January 2025
- Case
The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (A)
By: Tsedal Neeley, Levi Stroud, Ruth Page and Dave Habeeb
Pre-abstract:
This multimedia case should be assigned to students in advance of class. Instructors should consider the timing of making the (B) Case videos available to students, as they may reveal key case details.
Abstract:
Florian Hillen, co-founder and CEO of... View Details
Keywords: AI; Adoption; Diagnostics; Organization Design; Change Management; Disruption; Transformation; Health Care and Treatment; AI and Machine Learning; Technology Adoption; Disruptive Innovation; Technological Innovation; Management Style; Organizational Culture; Success; Technology Industry; Health Industry; United States
Neeley, Tsedal, Levi Stroud, Ruth Page, and Dave Habeeb. "The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (A)." Harvard Business School Multimedia/Video Case 425-720, January 2025.
- January 2025
- Supplement
The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (B)
By: Tsedal Neeley, Levi Stroud, Ruth Page and Dave Habeeb
Pre-abstract:
This multimedia case should be assigned to students in advance of class. Instructors should consider the timing of making the (B) Case videos available to students, as they may reveal key case details.
Abstract:
Florian Hillen, co-founder and CEO of... View Details
Keywords: AI; Adoption; Diagnostics; Organization Design; Change Management; Disruption; Transformation; Health Care and Treatment; AI and Machine Learning; Technology Adoption; Disruptive Innovation; Technological Innovation; Management Style; Organizational Culture; Success; Technology Industry; Health Industry; United States
Neeley, Tsedal, Levi Stroud, Ruth Page, and Dave Habeeb. "The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (B)." Harvard Business School Multimedia/Video Supplement 425-721, January 2025.
- 2025
- Article
Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments
By: Kosuke Imai and Michael Lingzhi Li
Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects under practical settings with... View Details
Imai, Kosuke, and Michael Lingzhi Li. "Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments." Journal of Business & Economic Statistics 43, no. 1 (2025): 256–268.
- December 2024
- Article
Proxy Advisory Firms and Corporate Shareholder Engagement
By: Aiyesha Dey, Austin Starkweather and Joshua White
We study how Institutional Shareholder Services (ISS) affect firms’ engagement with shareholders. Our analyses exploit a quasi-natural experiment using say-on-pay voting outcomes near a threshold that triggers ISS to review engagement activities. Firms receiving ISS... View Details
Dey, Aiyesha, Austin Starkweather, and Joshua White. "Proxy Advisory Firms and Corporate Shareholder Engagement." Review of Financial Studies 37, no. 12 (December 2024): 3877–3931.
- November 2024
- Article
Preference Externality Estimators: A Comparison of Border Approaches and IVs
By: Xi Ling, Wesley R. Hartmann and Tomomichi Amano
This paper compares two estimators—the Border Approach and an Instrumental Variable (IV) estimator—using a unified framework where identifying variation arises from “preference externalities,” following the intuition in Waldfogel (2003). We highlight two dimensions in... View Details
Ling, Xi, Wesley R. Hartmann, and Tomomichi Amano. "Preference Externality Estimators: A Comparison of Border Approaches and IVs." Management Science 70, no. 11 (November 2024): 7892–7910.
- November 2024
- Article
The Health Costs of Cost Sharing
By: Amitabh Chandra, Evan Flack and Ziad Obermeyer
What happens when patients suddenly stop their medications? We study the health consequences of drug interruptions caused by large, abrupt, and arbitrary changes in price. Medicare’s prescription drug benefit as-if-randomly assigns 65-year-olds a drug budget as a... View Details
Chandra, Amitabh, Evan Flack, and Ziad Obermeyer. "The Health Costs of Cost Sharing." Quarterly Journal of Economics 139, no. 4 (November 2024): 2037–2082.
- October 2024
- Article
Medicare Part D Protected-Class Policy Is Associated with Lower Drug Rebates
By: Pragya Kakani, Michael Anne Kyle, Amitabh Chandra and Luca Maini
Medicare Part D does not allow plans to exclude drugs in six protected classes from their formularies, which may limit plans’ ability to negotiate rebates and lead to higher spending. We estimated the association between protected-class status, US-level estimated... View Details
Keywords: Insurance; Health Care and Treatment; Governing Rules, Regulations, and Reforms; United States
Kakani, Pragya, Michael Anne Kyle, Amitabh Chandra, and Luca Maini. "Medicare Part D Protected-Class Policy Is Associated with Lower Drug Rebates." Health Affairs 43, no. 10 (October 2024): 1420–1427.
- 2024
- Working Paper
Does Private Equity Have Any Business Being in the Health Care Business?
By: Nori Gerardo Lietz and Zirui Song
Private Equity (“PE”) has come under increased scrutiny by the press, academics, and policymakers, as well as the public, for its investments in health care delivery. This scrutiny has been exacerbated by recent high profile hospital bankruptcies following PE... View Details
Lietz, Nori Gerardo, and Zirui Song. "Does Private Equity Have Any Business Being in the Health Care Business?" Harvard Business School Working Paper, No. 25-012, September 2024.
- 2024
- Article
Learning Under Random Distributional Shifts
By: Kirk Bansak, Elisabeth Paulson and Dominik Rothenhäusler
Algorithmic assignment of refugees and asylum seekers to locations within host
countries has gained attention in recent years, with implementations in the U.S.
and Switzerland. These approaches use data on past arrivals to generate machine
learning models that can... View Details
Bansak, Kirk, Elisabeth Paulson, and Dominik Rothenhäusler. "Learning Under Random Distributional Shifts." Proceedings of the International Conference on Artificial Intelligence and Statistics (AISTATS) 27th (2024).
- 2024
- Article
Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules
By: Michael Lingzhi Li and Kosuke Imai
A century ago, Neyman showed how to evaluate the efficacy of treatment using a randomized experiment under a minimal set of assumptions. This classical repeated sampling framework serves as a basis of routine experimental analyses conducted by today’s scientists across... View Details
Li, Michael Lingzhi, and Kosuke Imai. "Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules." Journal of Causal Inference 12, no. 1 (2024).
- August 2024
- Article
The Labor Market Effects of Loan Guarantee Programs
By: Jean-Noël Barrot, Thorsten Martin, Julien Sauvagnat and Boris Vallée
We investigate the labor market effects of a loan guarantee program targeting French SMEs during the financial crisis. Exploiting differences in regional treatment intensity in a border discontinuity design, we uncover a central trade-off for such interventions. While... View Details
Barrot, Jean-Noël, Thorsten Martin, Julien Sauvagnat, and Boris Vallée. "The Labor Market Effects of Loan Guarantee Programs." Review of Financial Studies 37, no. 8 (August 2024): 2315–2354.
- July–August 2024
- Article
Doing More with Less: Overcoming Ineffective Long-Term Targeting Using Short-Term Signals
By: Ta-Wei Huang and Eva Ascarza
Firms are increasingly interested in developing targeted interventions for customers with the best response,
which requires identifying differences in customer sensitivity, typically through the conditional average treatment
effect (CATE) estimation. In theory, to... View Details
Keywords: Long-run Targeting; Heterogeneous Treatment Effect; Statistical Surrogacy; Customer Churn; Field Experiments; Consumer Behavior; Customer Focus and Relationships; AI and Machine Learning; Marketing Strategy
Huang, Ta-Wei, and Eva Ascarza. "Doing More with Less: Overcoming Ineffective Long-Term Targeting Using Short-Term Signals." Marketing Science 43, no. 4 (July–August 2024): 863–884.
- 18 Apr 2024
- Lecture
Innovation Opportunities Created by COVID-19 Can Help: And How to Make Them Happen
The crush of patients created by COVID enabled the creation of sites for care outside the traditional hospital, such as retail pharmacies, ambulatory surgery centers, urgent care centers, telemedicine, and wireless sensors. Public policy mirrored these changes by... View Details
- 2024
- Working Paper
The Cram Method for Efficient Simultaneous Learning and Evaluation
By: Zeyang Jia, Kosuke Imai and Michael Lingzhi Li
We introduce the "cram" method, a general and efficient approach to simultaneous learning and evaluation using a generic machine learning (ML) algorithm. In a single pass of batched data, the proposed method repeatedly trains an ML algorithm and tests its empirical... View Details
Keywords: AI and Machine Learning
Jia, Zeyang, Kosuke Imai, and Michael Lingzhi Li. "The Cram Method for Efficient Simultaneous Learning and Evaluation." Working Paper, March 2024.
- 2023
- Working Paper
An Experimental Design for Anytime-Valid Causal Inference on Multi-Armed Bandits
By: Biyonka Liang and Iavor I. Bojinov
Typically, multi-armed bandit (MAB) experiments are analyzed at the end of the study and thus require the analyst to specify a fixed sample size in advance. However, in many online learning applications, it is advantageous to continuously produce inference on the... View Details
Liang, Biyonka, and Iavor I. Bojinov. "An Experimental Design for Anytime-Valid Causal Inference on Multi-Armed Bandits." Harvard Business School Working Paper, No. 24-057, March 2024.
- 2024
- Working Paper
Design of Panel Experiments with Spatial and Temporal Interference
By: Tu Ni, Iavor Bojinov and Jinglong Zhao
One of the main practical challenges companies face when running experiments (or A/B tests) over a panel is interference, the setting where one experimental unit's treatment assignment at one time period impacts another's outcomes, possibly at the following time... View Details
Keywords: Research
Ni, Tu, Iavor Bojinov, and Jinglong Zhao. "Design of Panel Experiments with Spatial and Temporal Interference." Harvard Business School Working Paper, No. 24-058, March 2024.
- March 2024
- Article
Medicare Price Negotiation and Pharmaceutical Innovation Following the Inflation Reduction Act
By: Matthew Vogel, Pragya Kakani, Amitabh Chandra and Rena M. Conti
The Inflation Reduction Act (IRA) requires Medicare to negotiate lower prices for some medicines with high Medicare spending. Using historical data from public and proprietary sources to apply the IRA's negotiation criteria retrospectively, we identify all drugs that... View Details
Keywords: Policy; Government Legislation; Health Care and Treatment; Negotiation; Price; Pharmaceutical Industry
Vogel, Matthew, Pragya Kakani, Amitabh Chandra, and Rena M. Conti. "Medicare Price Negotiation and Pharmaceutical Innovation Following the Inflation Reduction Act." Nature Biotechnology 42, no. 3 (March 2024): 406–412.
- January 2024
- Article
Population Interference in Panel Experiments
By: Kevin Wu Han, Guillaume Basse and Iavor Bojinov
The phenomenon of population interference, where a treatment assigned to one experimental unit affects another experimental unit’s outcome, has received considerable attention in standard randomized experiments. The complications produced by population interference in... View Details
Han, Kevin Wu, Guillaume Basse, and Iavor Bojinov. "Population Interference in Panel Experiments." Journal of Econometrics 238, no. 1 (January 2024).
- 2023
- Article
Balancing Risk and Reward: An Automated Phased Release Strategy
By: Yufan Li, Jialiang Mao and Iavor Bojinov
Phased releases are a common strategy in the technology industry for gradually releasing new products or updates through a sequence of A/B tests in which the number of treated units gradually grows until full deployment or deprecation. Performing phased releases in a... View Details
Li, Yufan, Jialiang Mao, and Iavor Bojinov. "Balancing Risk and Reward: An Automated Phased Release Strategy." Advances in Neural Information Processing Systems (NeurIPS) (2023).