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Publications

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      • 2025
      • Working Paper

      Tax Planning, Illiquidity, and Credit Risks: Evidence from DeFi Lending

      By: Lisa De Simone, Peiyi Jin and Daniel Rabetti
      This study establishes a plausible causal link between tax-planning-induced illiquidity and credit risks in lending markets. Exploiting an exogenous tax shock imposed by the Internal Revenue Service (IRS) on cryptocurrency gains, along with millions of transactions in... View Details
      Keywords: Cryptocurrency; Taxation; Financial Liquidity; Credit; Financing and Loans; Financial Markets
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      De Simone, Lisa, Peiyi Jin, and Daniel Rabetti. "Tax Planning, Illiquidity, and Credit Risks: Evidence from DeFi Lending." Working Paper, February 2025.
      • February 2025
      • Article

      Variation in Batch Ordering of Imaging Tests in the Emergency Department and the Impact on Care Delivery

      By: Jacob C. Jameson, Soroush Saghafian, Robert S. Huckman and Nicole Hodgson
      Objectives: To examine heterogeneity in physician batch ordering practices and measure the impact of a physician's tendency to batch order imaging tests on patient outcomes and resource utilization.
      Study Setting and Design: In this retrospective study, we used... View Details
      Keywords: Health Care; Operations Management; Productivity; Health Care and Treatment; Operations; Outcome or Result; Resource Allocation; Health Industry; United States
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      Jameson, Jacob C., Soroush Saghafian, Robert S. Huckman, and Nicole Hodgson. "Variation in Batch Ordering of Imaging Tests in the Emergency Department and the Impact on Care Delivery." Health Services Research 60, no. 1 (February 2025).
      • January 2025
      • Case

      The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (A)

      By: Tsedal Neeley, Levi Stroud, Ruth Page and Dave Habeeb
      Pre-abstract: This multimedia case should be assigned to students in advance of class. Instructors should consider the timing of making the (B) Case videos available to students, as they may reveal key case details.

      Abstract: Florian Hillen, co-founder... View Details
      Keywords: Diagnostics; Organization Design; Change Management; Disruption; Transformation; Health Care and Treatment; AI and Machine Learning; Technology Adoption; Technological Innovation; Management Style; Organizational Culture; Success; Technology Industry; Health Industry; United States
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      Neeley, Tsedal, Levi Stroud, Ruth Page, and Dave Habeeb. "The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (A)." Harvard Business School Multimedia/Video Case 425-720, January 2025.
      • January 2025
      • Supplement

      The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (B)

      By: Tsedal Neeley, Levi Stroud, Ruth Page and Dave Habeeb
      Pre-abstract: This multimedia case should be assigned to students in advance of class. Instructors should consider the timing of making the (B) Case videos available to students, as they may reveal key case details.

      Abstract: Florian Hillen, co-founder... View Details
      Keywords: Diagnostics; Organization Design; Change Management; Disruption; Transformation; Health Care and Treatment; AI and Machine Learning; Technology Adoption; Technological Innovation; Management Style; Organizational Culture; Success; Technology Industry; Health Industry; United States
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      Neeley, Tsedal, Levi Stroud, Ruth Page, and Dave Habeeb. "The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (B)." Harvard Business School Multimedia/Video Supplement 425-721, January 2025.
      • 2025
      • Article

      Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments

      By: Kosuke Imai and Michael Lingzhi Li
      Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects under practical settings with... View Details
      Keywords: AI and Machine Learning; Mathematical Methods; Analytics and Data Science
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      Imai, Kosuke, and Michael Lingzhi Li. "Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments." Journal of Business & Economic Statistics 43, no. 1 (2025): 256–268.
      • December 2024
      • Article

      Proxy Advisory Firms and Corporate Shareholder Engagement

      By: Aiyesha Dey, Austin Starkweather and Joshua White
      We study how Institutional Shareholder Services (ISS) affect firms’ engagement with shareholders. Our analyses exploit a quasi-natural experiment using say-on-pay voting outcomes near a threshold that triggers ISS to review engagement activities. Firms receiving ISS... View Details
      Keywords: Business and Shareholder Relations; Governing and Advisory Boards; Policy; Voting
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      Dey, Aiyesha, Austin Starkweather, and Joshua White. "Proxy Advisory Firms and Corporate Shareholder Engagement." Review of Financial Studies 37, no. 12 (December 2024): 3877–3931.
      • November 2024
      • Article

      Preference Externality Estimators: A Comparison of Border Approaches and IVs

      By: Xi Ling, Wesley R. Hartmann and Tomomichi Amano
      This paper compares two estimators—the Border Approach and an Instrumental Variable (IV) estimator—using a unified framework where identifying variation arises from “preference externalities,” following the intuition in Waldfogel (2003). We highlight two dimensions in... View Details
      Keywords: Econometrics; Casual Inference; Marketing; Economics; Advertising; Mathematical Methods
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      Ling, Xi, Wesley R. Hartmann, and Tomomichi Amano. "Preference Externality Estimators: A Comparison of Border Approaches and IVs." Management Science 70, no. 11 (November 2024): 7892–7910.
      • November 2024
      • Article

      The Health Costs of Cost Sharing

      By: Amitabh Chandra, Evan Flack and Ziad Obermeyer
      What happens when patients suddenly stop their medications? We study the health consequences of drug interruptions caused by large, abrupt, and arbitrary changes in price. Medicare’s prescription drug benefit as-if-randomly assigns 65-year-olds a drug budget as a... View Details
      Keywords: Outcome or Result; Health Care and Treatment; Budgets and Budgeting; Cost
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      Chandra, Amitabh, Evan Flack, and Ziad Obermeyer. "The Health Costs of Cost Sharing." Quarterly Journal of Economics 139, no. 4 (November 2024): 2037–2082.
      • October 2024
      • Article

      Medicare Part D Protected-Class Policy Is Associated with Lower Drug Rebates

      By: Pragya Kakani, Michael Anne Kyle, Amitabh Chandra and Luca Maini
      Medicare Part D does not allow plans to exclude drugs in six protected classes from their formularies, which may limit plans’ ability to negotiate rebates and lead to higher spending. We estimated the association between protected-class status, US-level estimated... View Details
      Keywords: Insurance; Health Care and Treatment; Governing Rules, Regulations, and Reforms; United States
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      Kakani, Pragya, Michael Anne Kyle, Amitabh Chandra, and Luca Maini. "Medicare Part D Protected-Class Policy Is Associated with Lower Drug Rebates." Health Affairs 43, no. 10 (October 2024): 1420–1427.
      • 2024
      • Working Paper

      Does Private Equity Have Any Business Being in the Health Care Business?

      By: Nori Gerardo Lietz and Zirui Song
      Private Equity (“PE”) has come under increased scrutiny by the press, academics, and policymakers, as well as the public, for its investments in health care delivery. This scrutiny has been exacerbated by recent high profile hospital bankruptcies following PE... View Details
      Keywords: Private Equity; Government Administration; Acquisition; Health Industry
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      Lietz, Nori Gerardo, and Zirui Song. "Does Private Equity Have Any Business Being in the Health Care Business?" Harvard Business School Working Paper, No. 25-012, September 2024.
      • 2024
      • Article

      Learning Under Random Distributional Shifts

      By: Kirk Bansak, Elisabeth Paulson and Dominik Rothenhäusler
      Algorithmic assignment of refugees and asylum seekers to locations within host countries has gained attention in recent years, with implementations in the U.S. and Switzerland. These approaches use data on past arrivals to generate machine learning models that can... View Details
      Keywords: AI and Machine Learning; Refugees; Employment
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      Bansak, Kirk, Elisabeth Paulson, and Dominik Rothenhäusler. "Learning Under Random Distributional Shifts." Proceedings of the International Conference on Artificial Intelligence and Statistics (AISTATS) 27th (2024).
      • 2024
      • Article

      Crucibles, Multiple Sensitive Periods, and Career Progression

      By: Prithwiraj Choudhury, Sunasir Dutta, Hise O. Gibson and Eric Lin
      We study the effects of crucible experiences along multiple sensitive periods on career progression. While prior literature has hinted that individuals can be imprinted during multiple sensitive periods, not just during the early career, there has been scant attention... View Details
      Keywords: Military Service; Personal Development and Career; Transformation; Power and Influence; Learning; Human Capital
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      Choudhury, Prithwiraj, Sunasir Dutta, Hise O. Gibson, and Eric Lin. "Crucibles, Multiple Sensitive Periods, and Career Progression." Academy of Management Proceedings (2024).
      • 2024
      • Article

      Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules

      By: Michael Lingzhi Li and Kosuke Imai
      A century ago, Neyman showed how to evaluate the efficacy of treatment using a randomized experiment under a minimal set of assumptions. This classical repeated sampling framework serves as a basis of routine experimental analyses conducted by today’s scientists across... View Details
      Keywords: AI and Machine Learning; Research
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      Li, Michael Lingzhi, and Kosuke Imai. "Neyman Meets Causal Machine Learning: Experimental Evaluation of Individualized Treatment Rules." Journal of Causal Inference 12, no. 1 (2024).
      • August 2024
      • Article

      The Labor Market Effects of Loan Guarantee Programs

      By: Jean-Noël Barrot, Thorsten Martin, Julien Sauvagnat and Boris Vallée
      We investigate the labor market effects of a loan guarantee program targeting French SMEs during the financial crisis. Exploiting differences in regional treatment intensity in a border discontinuity design, we uncover a central trade-off for such interventions. While... View Details
      Keywords: Labor; Financial Crisis; Policy; France
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      Barrot, Jean-Noël, Thorsten Martin, Julien Sauvagnat, and Boris Vallée. "The Labor Market Effects of Loan Guarantee Programs." Review of Financial Studies 37, no. 8 (August 2024): 2315–2354.
      • July–August 2024
      • Article

      Doing More with Less: Overcoming Ineffective Long-Term Targeting Using Short-Term Signals

      By: Ta-Wei Huang and Eva Ascarza
      Firms are increasingly interested in developing targeted interventions for customers with the best response, which requires identifying differences in customer sensitivity, typically through the conditional average treatment effect (CATE) estimation. In theory, to... View Details
      Keywords: Long-run Targeting; Heterogeneous Treatment Effect; Statistical Surrogacy; Customer Churn; Field Experiments; Consumer Behavior; Customer Focus and Relationships; AI and Machine Learning; Marketing Strategy
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      Huang, Ta-Wei, and Eva Ascarza. "Doing More with Less: Overcoming Ineffective Long-Term Targeting Using Short-Term Signals." Marketing Science 43, no. 4 (July–August 2024): 863–884.
      • 18 Apr 2024
      • Lecture

      Innovation Opportunities Created by COVID-19 Can Help: And How to Make Them Happen

      By: Regina E. Herzlinger
      The crush of patients created by COVID enabled the creation of sites for care outside the traditional hospital, such as retail pharmacies, ambulatory surgery centers, urgent care centers, telemedicine, and wireless sensors. Public policy mirrored these changes by... View Details
      Keywords: Policy; Health Pandemics; Health Care and Treatment; Innovation and Invention; Health Industry; Insurance Industry
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      "Innovation Opportunities Created by COVID-19 Can Help: And How to Make Them Happen." Fortnightly of Chicago, April 18, 2024.
      • 2024
      • Working Paper

      The Cram Method for Efficient Simultaneous Learning and Evaluation

      By: Zeyang Jia, Kosuke Imai and Michael Lingzhi Li
      We introduce the "cram" method, a general and efficient approach to simultaneous learning and evaluation using a generic machine learning (ML) algorithm. In a single pass of batched data, the proposed method repeatedly trains an ML algorithm and tests its empirical... View Details
      Keywords: AI and Machine Learning
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      Jia, Zeyang, Kosuke Imai, and Michael Lingzhi Li. "The Cram Method for Efficient Simultaneous Learning and Evaluation." Working Paper, March 2024.
      • 2023
      • Working Paper

      An Experimental Design for Anytime-Valid Causal Inference on Multi-Armed Bandits

      By: Biyonka Liang and Iavor I. Bojinov
      Typically, multi-armed bandit (MAB) experiments are analyzed at the end of the study and thus require the analyst to specify a fixed sample size in advance. However, in many online learning applications, it is advantageous to continuously produce inference on the... View Details
      Keywords: Analytics and Data Science; AI and Machine Learning; Mathematical Methods
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      Liang, Biyonka, and Iavor I. Bojinov. "An Experimental Design for Anytime-Valid Causal Inference on Multi-Armed Bandits." Harvard Business School Working Paper, No. 24-057, March 2024.
      • 2024
      • Working Paper

      Design of Panel Experiments with Spatial and Temporal Interference

      By: Tu Ni, Iavor Bojinov and Jinglong Zhao
      One of the main practical challenges companies face when running experiments (or A/B tests) over a panel is interference, the setting where one experimental unit's treatment assignment at one time period impacts another's outcomes, possibly at the following time... View Details
      Keywords: Research
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      Ni, Tu, Iavor Bojinov, and Jinglong Zhao. "Design of Panel Experiments with Spatial and Temporal Interference." Harvard Business School Working Paper, No. 24-058, March 2024.
      • March 2024
      • Article

      Medicare Price Negotiation and Pharmaceutical Innovation Following the Inflation Reduction Act

      By: Matthew Vogel, Pragya Kakani, Amitabh Chandra and Rena M. Conti
      The Inflation Reduction Act (IRA) requires Medicare to negotiate lower prices for some medicines with high Medicare spending. Using historical data from public and proprietary sources to apply the IRA's negotiation criteria retrospectively, we identify all drugs that... View Details
      Keywords: Policy; Government Legislation; Health Care and Treatment; Negotiation; Price; Pharmaceutical Industry
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      Vogel, Matthew, Pragya Kakani, Amitabh Chandra, and Rena M. Conti. "Medicare Price Negotiation and Pharmaceutical Innovation Following the Inflation Reduction Act." Nature Biotechnology 42, no. 3 (March 2024): 406–412.
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