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- April 2025
- Teaching Note
ZEISS: Commercializing Science
By: Maria P. Roche
Teaching Note for HBS Case No. 725-359. View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Technology Industry; Technology Industry; Germany; Europe
- April 2025
- Supplement
ZEISS: Commercializing Science
By: Maria P. Roche and Richie Zitomer
Spreadsheet Supplement for HBS Case No. 725-359. View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Technology Industry; Technology Industry; Germany; Europe
- 2025
- Working Paper
The Cybernetic Teammate: A Field Experiment on Generative AI Reshaping Teamwork and Expertise
By: Fabrizio Dell'Acqua, Charles Ayoubi, Hila Lifshitz, Raffaella Sadun, Ethan Mollick, Lilach Mollick, Yi Han, Jeff Goldman, Hari Nair, Stew Taub and Karim R. Lakhani
We examine how artificial intelligence transforms the core pillars of collaboration—
performance, expertise sharing, and social engagement—through a pre-registered field
experiment with 776 professionals at Procter & Gamble, a global consumer packaged goods
company.... View Details
- March 2025
- Case
Metaphysic AI: Rethinking the Value of Human Expertise
By: Zoë B. Cullen, Shikhar Ghosh and Shweta Bagai
In early 2025, Thomas Graham, CEO of Metaphysic, a leading AI generative video company confronted fundamental questions about who should control digital identity in a world where AI could perfectly recreate human likeness. Founded in 2021, Metaphysic first rose to fame... View Details
- January 2025
- Case
Davivienda Bank's Upskilling and Reskilling Strategy in Colombia (Abridged)
By: Jorge Tamayo, Raffaella Sadun and Jenyfeer Martinez Buitrago
Set in 2022, this abridged case examines the digital transformation strategy of Davivienda—a leading player in Colombia’s commercial banking sector and one of the companies belonging to Grupo Bolívar, a major Colombian conglomerate—and the bank’s upskilling and... View Details
Keywords: Change Management; Transformation; Decision Choices and Conditions; Digital Strategy; Digital Transformation; Internet and the Web; Mobile and Wireless Technology; Innovation and Management; Innovation Strategy; Growth and Development Strategy; Business Strategy; Corporate Strategy; Talent and Talent Management; Training; Organizational Culture; Banking Industry; Latin America; Central America; South America; Colombia
- January 2025 (Revised April 2025)
- Case
Blue Frontier: Disrupting Air Conditioning
By: Rosabeth Moss Kanter and Jacob A. Small
Serial entrepreneur Daniel Betts founded Blue Frontier in South Florida to offer a climate-friendly solution to increase air conditioning efficiency and dehumidify using new technology he developed. Backed by significant venture capital, Blue Frontier had to choose... View Details
- December 2024
- Case
Xtalic
By: Joshua Lev Krieger and Jim Matheson
This case study examines the commercialization efforts of Xtalic, a startup founded by MIT scientists based on their discovery of a novel material science method to protect metal substrates. The case focuses on the strategic decisions involved in bringing this... View Details
- 2024
- Working Paper
Charting (and Updating) the Path: A Bayesian Perspective on Entrepreneurial Learning
This chapter explores two distinct modes of entrepreneurial learning: assessing
venture viability and choosing between alternative development paths. It introduces
a framework for decomposing venture viability into technological feasibility, commercial
potential and... View Details
- 2024
- Working Paper
Catalysts for Climate Solutions: Corporate Responses to Venture Capital Financing of Climate-tech Startups
By: Shirley Lu, George Serafeim and Simon Xu
We study whether incumbent firms increase their product focus on climate solutions in response to venture capital (VC) financing of climate-tech startups. Using large language models to measure a firm's focus on climate solutions, we find that incumbents in similar... View Details
- 2024
- Working Paper
The New Digital Divide
By: Mayana Pereira, Shane Greenstein, Raffaella Sadun, Prasanna Tambe, Lucia Ronchi Darre, Tammy Glazer, Allen Kim, Rahul Dodhia and Juan Lavista Ferres
We build and analyze new metrics of digital usage that leverage telemetry data collected by Microsoft during operating system updates across forty million Windows devices in U.S. households. These measures of US household digital usage are much more comprehensive than... View Details
- August 2024
- Case
Iogen: Decarbonizing Hard-to-Abate Sectors
By: George Serafeim, Charlotte Foody and John Mulliken
Brian Foody, CEO of Iogen Corporation, was an early leader in advanced biofuels, developing a range of technologies to transform agricultural waste into transportation fuel. With $100 million in revenue and 350 patents across various biofuel technologies, Iogen was... View Details
- August 2024 (Revised November 2024)
- Case
Commonwealth Fusion Systems: Born at Scale
This case study chronicles the journey of Commonwealth Fusion Systems (CFS) on its ambitious mission to commercialize fusion energy and become the world’s leading provider of fusion power plants. Emerging from a “special arrangement” with MIT's Plasma Science and... View Details
- July 2024
- Case
ZEISS: Commercializing Science
By: Maria P. Roche, Carlota Moniz and Daniela Beyersdorfer
Karl Lamprecht, President and CEO of the ZEISS AG Group, mused on how far ZEISS had come in 175 years of being a pioneer in optics, and how the course he had charted since taking the helm of the company could keep it on track. In his role, he oversaw the four core... View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Technology Industry; Technology Industry; Germany; Europe
- July 2024
- Article
Chatbots and Mental Health: Insights into the Safety of Generative AI
By: Julian De Freitas, Ahmet Kaan Uğuralp, Zeliha Uğuralp and Stefano Puntoni
Chatbots are now able to engage in sophisticated conversations with consumers. Due to the ‘black box’ nature of the algorithms, it is impossible to predict in advance how these conversations will unfold. Behavioral research provides little insight into potential safety... View Details
- May 2024
- Teaching Note
AI Wars
By: Andy Wu and Matt Higgins
Teaching Note for HBS Case No. 723-434. In 2024, the world was looking to Google to see what the search giant and long-time putative technical leader in artificial intelligence (AI) would do to compete in the massively hyped technology of generative AI popularized over... View Details
- April 2024 (Revised August 2024)
- Case
The Engine
By: Joshua Lev Krieger, Jim Matheson, Fiona Murray and Nicholas Christman
The Engine, a venture capital firm founded by MIT to fill a gap in the technology funding landscape by commercializing breakthrough science and technology. Led by managing partner and CEO Katie Rae, the Engine's unique approach involved an unusually longer fund life,... View Details
- April–May 2024
- Article
Gone with the Big Data: Institutional Lender Demand for Private Information
By: Jung Koo Kang
I explore whether big-data sources can crowd out the value of private information acquired through lending relationships. Institutional lenders have been shown to exploit their access to borrowers’ private information by trading on it in financial markets. As a shock... View Details
- March 2024
- Case
Biomanufacturing Decentralization by Stämm
By: Paul A. Gompers, Jenyfeer Martínez Buitrago and Mariana Cal
In Buenos Aires, Argentina, cousins Llamazares and D’Alvia founded Stämm, a startup based on the idea of decentralizing biomanufacturing processes and downsizing biotech facilities. After raising its seed and series A rounds, and while finalizing its series B round in... View Details
Keywords: Business Model; Business Startups; Entrepreneurship; Venture Capital; Selection and Staffing; Technological Innovation; Science-Based Business; Business Strategy; Commercialization; Growth and Development Strategy; Product Launch; Research and Development; Biotechnology Industry; Latin America; South America; Argentina; Buenos Aires
- March 2024
- Teaching Note
CoPilot(s): Generative AI at Microsoft and GitHub
By: Frank Nagle and Maria P. Roche
This teaching note is the companion to case N9-624-010 CoPilot(s): Generative AI at Microsoft and GitHub, which takes place in late 2021. The case briefly describes the history of both GitHub and Microsoft with a particular focus on open source software (OSS)—software... View Details
- February 2024
- Teaching Note
Fusion Industry Association: Igniting the Future of Clean Energy
Teaching Note for HBS Case No. 624-064. This Teaching Note explores the Fusion Industry Association's efforts to advance commercial fusion energy, highlighting challenges in innovation, regulation, market structure, and financing within the emerging technology sector... View Details