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2025
Working Paper

Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance

By: Justine Boudou and Maria Roche

In this paper, we examine how a startup’s knowledge foundations—embedded in its core technology—influence its performance in the exit market. Using a dataset of 1,006 biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1) the degree of... View Details

Keywords: Firm Performance; Knowledge Foundations; Exits; Academic Startups; Inventor-founder; Specialized Scientific Knowledge; Competitive Advantage; Value Creation; Research; Information Publishing; Business Startups; Entrepreneurship

January 2020
Article

Jack of All Trades and Master of Knowledge: The Role of Diversification in New Distant Knowledge Integration

By: Frank Nagle and Florenta Teodoridis

We consider the role of individual-level diversification as a mechanism through which skilled researchers engage in successful exploration—recognizing and integrating new knowledge external to one’s domains of expertise. To approach an ideal experiment, we (1) employ a... View Details

Keywords: Individual-level Knowledge Diversification; Novel Knowledge; Knowledge Acquisition; Diversification; Innovation and Invention; Research

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June 2010 (Revised January 2011)
Case

Scientific Glass Incorporated: Inventory Management

By: Steven C. Wheelwright and William Schmidt

Scientific Glassware is a fast-growing, privately held company that provides specialized glassware for laboratory and research facilities. Excess inventory is tying up extra capital needed to fund the company's expansion plans. The newly hired Manager of Inventory... View Details

Keywords: Inventory Control; Inventory Management; Materials Management; Order Processing; Warehousing; Salesforce Management; Logistics; Operations; Order Taking and Fulfillment; Finance; Consumer Products Industry; Technology Industry

August 2008
Article

Ethnic Scientific Communities and International Technology Diffusion

By: William R. Kerr

This study explores the importance of knowledge transfer for international technology diffusion by examining ethnic scientific and entrepreneurial communities in the US and their ties to their home countries. US ethnic research communities are quantified by applying an... View Details

Keywords: Information Technology; Ethnicity; Production; Integration; Knowledge Sharing; Patents; Employment; Performance Productivity; Entrepreneurship; Change; Developing Countries and Economies; Immigration; China; United States

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October 2016
Article

Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science

By: Kevin J. Boudreau, Eva Guinan, Karim R. Lakhani and Christoph Riedl

Selecting among alternative innovative projects is a core management task in all innovating organizations. In this paper, we focus on the evaluation of frontier scientific research projects. We argue that the "intellectual distance" between the knowledge embodied in... View Details

Keywords: Knowledge; Innovation; Novelty; Evaluation; Resource Allocation; Decision Choices and Conditions; Innovation and Management; Science-Based Business; Experience and Expertise

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Research Summary

Recruiting specialized inventors into young organizations

Commercializing nascent technologies may require the expertise of those intimately involved in the original invention, especially when tacit knowledge is essential. Yet the organization home to the original invention may not serve as the best commercialization... View Details

2010
Working Paper

Performance Tradeoffs in Team Knowledge Sourcing

By: Bradley R. Staats, Melissa Valentine and Amy C. Edmondson

This research examines how teams organize knowledge sourcing (obtaining access to others' knowledge or expertise) and investigates the performance trade-offs involved in two approaches to knowledge sourcing in teams. One approach a team can take is to specialize, such... View Details

Keywords: Information Management; Knowledge Sharing; Knowledge Use and Leverage; Performance Efficiency; Performance Productivity; Quality; Groups and Teams; Information Technology Industry; India

2020
Working Paper

Scientific Production: An Exploration into Organization, Resource Allocation, and Funding

By: Jerry Thursby, Marie Thursby, Karim R. Lakhani, Kyle R. Myers, Nina Cohodes, Sarah Bratt, Dennis Byrski, Hannah Cohoon and Maria Roche

Production of scientific knowledge is core to civilizational advancement in economic and material wellbeing of societies. Despite its fundamental importance, however, a systematic effort to quantitatively study the factors underlying scientific production, particularly... View Details

Keywords: Funding; Science; Knowledge; Research; Information Management; Resource Allocation

Article

Dismantling Knowledge Boundaries at NASA: The Critical Role of Professional Identity in Open Innovation

By: Hila Lifshitz - Assaf

Using a longitudinal in-depth field study at NASA, I investigate how the open, or peer-production, innovation model affects R&D professionals, their work, and the locus of innovation. R&D professionals are known for keeping their knowledge work within clearly defined... View Details

Keywords: Innovation; Knowledge Boundaries; Boundary Work; Professional Identity; Open Innovation; Identity Work; Technological Change; Nasa; Innovation and Invention; Knowledge; Science; Technology; Engineering; Change; Aerospace Industry; North and Central America

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July 2020 (Revised September 2020)
Case

The Honor Foundation: Accessing Special Operations Talent

By: Boris Groysberg and John Masko

In 2020, The Honor Foundation (THF), a nonprofit dedicated to helping U.S. military special operators to transition into civilian careers, was facing a series of strategic challenges. THF had been founded in 2013 by former Navy SEAL trainee Joe Musselman, who observed... View Details

05 Jan 2011
Op-Ed

Funding Unpredictability Around Stem-Cell Research Inflicts Heavy Cost on Scientific Progress

million to $5 million, with most of that money coming from grants from institutions like the National Institutes of Health (NIH). “Funding can be canceled with the stroke of a pen.” The NIH allocates money to researchers whose proposals are reviewed by a panel of... View Details

Keywords: by William Sahlman; Biotechnology; Health; Pharmaceutical

2011
Chapter

Knowledge Structures and Innovation: Useful Abstractions and Unanswered Questions

By: Gautam Ahuja and Elena Novelli

We examine the received research on organizational knowledge structures with a special focus on their link to innovation. We note that the literature has used the term knowledge structure to represent three quite distinct components of organizational knowledge: the... View Details

Keywords: Knowledge Management; Innovation and Invention

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2006
Chapter

Between 'Knowledge' and 'the Economy': Notes on the Scientific Study of Designs

By: Carliss Y. Baldwin and Kim B. Clark

Keywords: Design; Knowledge; Economy

07 May 2009
Working Paper Summaries

Broadening Focus: Spillovers and the Benefits of Specialization in the Hospital Industry

Keywords: by Jonathan R. Clark & Robert S. Huckman; Health

November 2020
Article

Migrant Inventors and the Technological Advantage of Nations

By: Dany Bahar, Prithwiraj Choudhury and Hillel Rapoport

We investigate the relationship between the presence of migrant inventors and the dynamics of innovation in the migrants’ receiving countries. We find that countries are 25 to 60 percent more likely to gain advantage in patenting in certain technologies given a twofold... View Details

Keywords: Innovation; Migration; Patent; Knowledge; Innovation and Invention; Immigration; Patents; Information Technology; Knowledge Dissemination

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2007
Chapter

Collaborative R&D in Management: The Practical Experience of Fenix and TruePoint in Bridging the Divide Between Scientific and Managerial Goals

By: Michael Beer and Niclas Adler

The gap between theory and practice has been of concern to both practitioners and academics, yet other than pleas to close the gap with more accessible writing by academics and more interest in research by practitioners few systematic efforts have been made to close... View Details

Keywords: Transformation; Knowledge Management; Management; Goals and Objectives; Performance Effectiveness; Performance Improvement; Practice; Research and Development; Social and Collaborative Networks; Theory; Value; United States

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Forthcoming
Article

You've Got Mail! The Late 19th-Century U.S. Postal Service Expansion, Firm Creation, and Firm Performance

By: Astrid Marinoni and Maria P. Roche

This paper examines the impact of the expansion of the US Postal Service in the late 19th century on firm creation and performance. Utilizing newly digitized archival data on historic business establishments, post office locations, and road networks in California,... View Details

Keywords: Institutional Innovation; Knowledge Exchange; US Postal Service; Firm Performance; Infrastructure; Expansion; Government Administration; Communication; Business History; Entrepreneurship; Public Administration Industry; California

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06 Jun 2016
Research & Ideas

Skills and Behaviors that Make Entrepreneurs Successful

can include small “lifestyle” businesses, multi-generational family businesses, high-growth, venture funded technology businesses, and new ventures designed to commercialize breakthrough discoveries in life sciences, clean tech, and other View Details

Keywords: by HBS Working Knowledge

June 2023
Article

How New Ideas Diffuse in Science

By: Mengjie Cheng, Daniel Scott Smith, Xiang Ren, Hancheng Cao, Sanne Smith and Daniel A. McFarland

What conditions help new ideas spread? Can knowledge entrepreneurs’ position and develop new ideas in ways that help them take off? Most innovation research focuses on products and their reference. That focus ignores the ideas themselves and the broader ideational... View Details

Keywords: Innovation Adoption; Natural Language Processing; Knowledge; Science; Innovation and Invention; Knowledge Sharing; Analytics and Data Science

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Research Summary

Overview

Professor Myers studies the ways people learn from their own—and others’—experiences at work, with a particular emphasis on learning in health care organizations and emergency medical contexts. Though his interest is in individual-level learning, he focuses in... View Details

Keywords: Learning And Development; Learning Organizations; Learning By Doing; Health Care Industry; Innovation; Identity Construction; Medical Error; Knowledge Development; Knowledge Sharing; Knowledge Work; Learning; Leadership Development; Knowledge Management; Collaborative Innovation and Invention; Health Industry; United States; Singapore; Asia

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