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Publications
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- 2025
- Working Paper
Where Discovery Happens: Research Institutions and Fundamental Knowledge in the Life-Sciences
By: Amitabh Chandra and Connie Xu
Fundamental knowledge in the life sciences has consequential implications for medicine and subsequent medical innovations. Using publications in leading life science journals to measure fundamental knowledge, we document large agglomerations in the institutions where... View Details
- April 2025 (Revised April 2025)
- Case
JPMorganChase: Leadership in the Age of GenAI
By: Iavor I. Bojinov, Karim R. Lakhani and David Lane
This case study examines JPMorgan Chase's (JPMC) journey in adopting and implementing Generative AI (GenAI) following the release of ChatGPT. It outlines JPMC's initial cautious approach focused on data security, followed by strategic investments in internal platforms... View Details
Keywords: Banks and Banking; Governance Controls; Information Technology; AI and Machine Learning; Analytics and Data Science; Cybersecurity; Digital Platforms; Digital Transformation; Information Management; Information Infrastructure; Technology Adoption; Job Cuts and Outsourcing; Knowledge Management; Knowledge Sharing; Leading Change; Growth and Development Strategy; Marketing; Product Development; Performance Improvement; Customization and Personalization; Financial Services Industry; United States
- 2025
- Working Paper
Transferability MATTRs: Towards Understanding Antecedents of Strategic Licensing
By: Dafna F. Bearson and Maria P. Roche
This paper examines the antecedents of firms’ decisions to license intellectual property
(IP). We propose a conceptual framework emphasizing two critical factors: (1) transferability,
which we define as the ease of moving knowledge embodied in inventions across
firm... View Details
- 2024
- Working Paper
The Value of AI Innovations
By: Wilbur Xinyuan Chen, Terrence Tianshuo Shi and Suraj Srinivasan
We study the value of AI innovations as it diffuses across general and application sectors, using the United States Patent and Trademark Office’s (USPTO) AI patent dataset. Investors value these innovations more than others, as AI patents exhibit a 9% value premium,... View Details
- 2024
- Working Paper
Old Moats for New Models: Openness, Control, and Competition in Generative AI
By: Pierre Azoulay, Joshua L. Krieger and Abhishek Nagaraj
Drawing insights from the field of innovation economics, we discuss the likely competitive environment shaping generative AI advances. Central to our analysis are the concepts of appropriability—whether firms in the industry are able to control the knowledge generated... View Details
- 2025
- Working Paper
Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance
By: Justine Boudou and Maria Roche
In this paper, we examine how a startup’s knowledge foundations—embedded in its
core technology—influence its performance in the exit market. Using a dataset of 1,006
biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1)
the degree of... View Details
- March, 2023
- Article
Academic Entrepreneurship: Entrepreneurial Advisors and Their Advisees' Outcomes
By: Maria P. Roche
The transfer of complex knowledge and skills is difficult, often requiring intensive interaction and extensive periods of co-working between a mentor and mentee, which is particularly true in apprenticeship-like settings and on-the-job training. This paper studies a... View Details
- June 2022
- Article
Conservatism Gets Funded? A Field Experiment on the Role of Negative Information in Novel Project Evaluation
By: Jacqueline N. Lane, Misha Teplitskiy, Gary Gray, Hardeep Ranu, Michael Menietti, Eva C. Guinan and Karim R. Lakhani
The evaluation and selection of novel projects lies at the heart of scientific and technological innovation, and yet there are persistent concerns about bias, such as conservatism. This paper investigates the role that the format of evaluation, specifically information... View Details
- Article
Act Like a Scientist: Great Leaders Challenge Assumptions, Run Experiments, and Follow the Evidence
By: Stefan Thomke and Gary W. Loveman
Though they’ve been warned for decades about the dangers of overrelying on gut instinct and personal experience, managers keep failing to critically examine—much less challenge—the ideas their decisions are based on. To correct this problem they need to think and act... View Details
- Article
A Career Life-Cycle Perspective on Women's Health and Safety
By: Robert S. Kaplan, Chizoba L. Chukwura, Gregory H. Gorman, Vivian S. Lee, Chester B. Good, Kathleen L. Martin, Gregory A. Ator and Michael D. Parkinson
Women's health has demanded more attention from employers as women integrated into the workforce. Traditionally male-dominant fields and occupations require special attention to workplace design, physical standards for entry, employment practices, equipment, and health... View Details
- March 2021
- Article
Increasing the Level of Abstraction as a Strategy for Accelerating the Adoption of Complex Technologies
By: Willy C. Shih
Many new technologies are complex and embody high levels of technical sophistication, and applying them should require significant knowledge and experience. Yet, the rapid adoption and incorporation of these technologies into other innovations seems inconsistent with... View Details
- July 2020 (Revised September 2020)
- Case
The Honor Foundation: Accessing Special Operations Talent
By: Boris Groysberg and John Masko
In 2020, The Honor Foundation (THF), a nonprofit dedicated to helping U.S. military special operators to transition into civilian careers, was facing a series of strategic challenges. THF had been founded in 2013 by former Navy SEAL trainee Joe Musselman, who observed... View Details
Keywords: Experience and Expertise; Talent and Talent Management; Curriculum and Courses; Executive Education; Social Entrepreneurship; National Security; Recruitment; Retention; Job Interviews; Job Search; Knowledge Use and Leverage; Leadership Development; Leadership Style; Crisis Management; Mission and Purpose; Retirement; Nonprofit Organizations; War; Education Industry; San Diego; Virginia
- 2020
- Working Paper
When Do Experts Listen to Other Experts? The Role of Negative Information in Expert Evaluations for Novel Projects
By: Jacqueline N. Lane, Misha Teplitskiy, Gary Gray, Hardeep Ranu, Michael Menietti, Eva C. Guinan and Karim R. Lakhani
The evaluation of novel projects lies at the heart of scientific and technological innovation, and yet literature suggests that this process is subject to inconsistency and potential biases. This paper investigates the role of information sharing among experts as the... View Details
- 2020
- Working Paper
Scientific Production: An Exploration into Organization, Resource Allocation, and Funding
By: Jerry Thursby, Marie Thursby, Karim R. Lakhani, Kyle R. Myers, Nina Cohodes, Sarah Bratt, Dennis Byrski, Hannah Cohoon and Maria Roche
Production of scientific knowledge is core to civilizational advancement in economic and material wellbeing of societies. Despite its fundamental importance, however, a systematic effort to quantitatively study the factors underlying scientific production, particularly... View Details
- November 2019 (Revised April 2020)
- Technical Note
The Life Sciences Revolution: A Technical Primer
By: Gary P. Pisano, William J. Anderson, Amitabh Chandra, Clarissa Ceruti and Stephanie Oestreich
For more than two decades, scientific advances have been driving profound changes in drug discovery and the drug industry itself. This case provides an overview and description of these technical and scientific advances. Written for the nonscientific reader, it may be... View Details
- September 2019 (Revised December 2019)
- Case
Google: To TVC or Not to TVC?
By: William R. Kerr and Carl Kreitzberg
In late 2018, evidence emerged that many of Google’s temporary help agency workers, vendors, and independent contractors (“TVCs”) were unhappy with the company. TVCs, who reportedly made up 49.95% of Google’s 170,000-person global workforce, had raised concerns of... View Details
Keywords: Workforce; Independent Contractors; Talent Management; Silicon Valley; Google; Employee Attitude; Employee Compensation; Employee Engagement; Future Of Work; Innovation; Innovation And Strategy; Inequality; Talent Acquisition; Labor; Talent and Talent Management; Strategy; Technological Innovation; Employees; Attitudes; Innovation and Management; Human Resources; Equality and Inequality; Information Technology Industry; United States; San Francisco
- May 2017 (Revised November 2017)
- Case
Cotopaxi: Managing Growth for Good
By: Andy Wu and Laura Huang
Cotopaxi, an innovative outdoor gear business targeting millennials, focuses on profit and social impact. This registered benefit corporation was formed by Davis Smith who coalesced his experiences as a Wharton MBA student along with professional knowledge from an... View Details
- October 2016
- Article
Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science
By: Kevin J. Boudreau, Eva Guinan, Karim R. Lakhani and Christoph Riedl
Selecting among alternative innovative projects is a core management task in all innovating organizations. In this paper, we focus on the evaluation of frontier scientific research projects. We argue that the "intellectual distance" between the knowledge embodied in... View Details
- Article
A Case for Contextual Intelligence
By: Tarun Khanna
In this perspective, I make a case for entrepreneurs and academics alike to focus on what I have referred to elsewhere as Contextual Intelligence, the ability to understand the limits of our knowledge, and to adapt that knowledge to a context different from the one in... View Details
- 2015
- Other Unpublished Work
Do Managers Have a Role to Play in Sustaining the Institutions of Capitalism?
By: Rebecca Henderson and Karthik Ramanna
In a capitalist system based on free markets, do managers have responsibilities to the system itself? If they do, should these responsibilities shape their behavior when they engage in the political processes that structure the institutions of capitalism? The... View Details