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- October 2024
- Case
Reed Group and Succession in a Family Business: An Impossible Job to Fill?
By: Lauren H. Cohen and Tonia Labruyere
James Reed had taken over Reed Group, the recruitment and career services company his father had founded and built, in 1994. He was now reflecting on succession planning and other challenges that lay ahead: with no obvious choice among his family members, he needed to... View Details
- September–October 2024
- Article
Boards Need a New Approach to Technology
By: Tarun Khanna, Mary C. Beckerle and Nabil Y. Sakkab
The boards of too many publicly traded companies are downright timid when considering matters involving science and technology. More often than not, they focus on security and digitization—a defensive posture that fails to consider the bigger opportunities emerging... View Details
- October 2024
- Background Note
Space Capitalism and the Final Frontier
By: Sophus A. Reinert, Ryan Spatz and Bobby Faith
- August 2024
- Case
Sky Therapeutics: Innovating in Digital Therapeutics
By: Satish Tadikonda, Olivia Reszczynski and William Marks
Shad Faraz and Alex Youssef were intrigued by the opportunities in the relatively new area of Digital Therapeutics. Despite initial successes, early entrants had struggled with reimbursement and revenue-predictability challenges. However, venture investors still... View Details
- August 2024
- Case
Zipline: Expanding the World's Largest Autonomous Drone Delivery Network
By: Tarun Khanna and George Gonzalez
Zipline initially established the world's largest logistics network in Rwanda and Ghana by delivering medical supplies to hospitals via automated drones from a centralized hub. The company is now looking to expand to the U.S. home delivery market and designed a... View Details
- July 2024
- Article
How Artificial Intelligence Constrains Human Experience
By: A. Valenzuela, S. Puntoni, D. Hoffman, N. Castelo, J. De Freitas, B. Dietvorst, C. Hildebrand, Y.E. Huh, R. Meyer, M. Sweeney, S. Talaifar, G. Tomaino and K. Wertenbroch
Many consumption decisions and experiences are digitally mediated. As a consequence, consumer behavior is increasingly the joint product of human psychology and ubiquitous algorithms (Braun et al. 2024; cf. Melumad et al. 2020). The coming of age of Large Language... View Details
- June 2024
- Case
Lana Ghanem: Pushing the Boundaries of Health Care Through Venture Capital
By: Joshua D. Margolis and Ahmed Dahawy
Lana Ghanem, managing director of Hikma Ventures, the corporate venture arm of larger pharmaceutical group Hikma, is considering how to grow the venture arm as well as progress her own career. Over the past few years Hikma's executive team had been pressuring the... View Details
- 2024
- Working Paper
Incrementality Representation Learning: Synergizing Past Experiments for Intervention Personalization
This paper introduces Incrementality Representation Learning (IRL), a novel multitask representation learning framework that predicts heterogeneous causal effects of marketing interventions. By leveraging past experiments, IRL efficiently designs and targets... View Details
- June 2024
- Article
Real Growth in Space Manufacturing Output Substantially Exceeds Growth in the Overall Space Economy
By: Tina Highfill and Matthew Weinzierl
Accurately measuring real economic output in the space economy is made difficult by the rapid increase in capabilities and decrease in prices of launch and satellite technologies achieved over the past two decades. Nominal measures of output in space will tend to... View Details
- April 2024 (Revised August 2024)
- Case
The Engine
By: Joshua Lev Krieger, Jim Matheson, Fiona Murray and Nicholas Christman
The Engine, a venture capital firm founded by MIT to fill a gap in the technology funding landscape by commercializing breakthrough science and technology. Led by managing partner and CEO Katie Rae, the Engine's unique approach involved an unusually longer fund life,... View Details
- February 2024 (Revised May 2024)
- Case
Moving Science: The Rowland Institute at Harvard
By: Maria P. Roche
Set in 2022, this case describes the considerations involved in organizing the physical relocation of the Rowland Institute at Harvard (RIH), a research institute established in 1980 by Edwin H. Land, the founder of the Polaroid Corporation, for the advancement of... View Details
- January 2024
- Case
Relativity Space, Vertical Integration, and Additive Manufacturing's Role in Space
By: Matthew C. Weinzierl, Brendan L. Rosseau and Jack Goodwin
- January 2024
- Case
Huawei: Resilience amid Autarky and Adversity
By: William C. Kirby and Daniel Fu
In September 2023, Huawei made a dramatic return to the global smartphone space with the launch of its Mate 60 Pro smartphone, equipped with an indigenously designed, 7nm chip. This came despite a myriad of export controls and restrictions imposed against the company... View Details
Keywords: International Strategy; Semiconductors; Smartphone; Government And Politics; Government And Business; Digital Infrastructure; 5G; Political Risk; Business and Government Relations; Global Strategy; Multinational Firms and Management; Governing Rules, Regulations, and Reforms; AI and Machine Learning; Mobile and Wireless Technology; Leadership; Retirement; Corporate Strategy; Technology Industry; China; United States; Europe; Asia; Middle East
- December 18, 2023
- Article
Are Everywhere Stores the New Face of Retail?
By: David R. Bell, Santiago Gallino and Antonio Moreno
Historically, customer engagement and product fulfillment occurred in the same place — a traditional retail store. But today, retailers are beginning to explore how they can create opportunities for customers to engage with products in native environments. A related... View Details
- 2023
- Article
MoPe: Model Perturbation-based Privacy Attacks on Language Models
By: Marvin Li, Jason Wang, Jeffrey Wang and Seth Neel
Recent work has shown that Large Language Models (LLMs) can unintentionally leak sensitive information present in their training data. In this paper, we present Model Perturbations (MoPe), a new method to identify with high confidence if a given text is in the training... View Details
- November 2023 (Revised April 2024)
- Case
Khanmigo: Revolutionizing Learning with GenAI
By: William A. Sahlman, Allison M. Ciechanover and Emily Grandjean
Already a leader in the edtech space since its 2008 launch, Khan Academy was now one of the first edtech organizations to embrace generative artificial intelligence ("genAI"). In March 2023, Khan Academy began beta testing Khanmigo, a genAI “guide” and tutor built with... View Details
- October 2023 (Revised April 2024)
- Case
TetraScience: Unlocking the Power of Scientific Data
By: Satish Tadikonda and William Marks
After pivoting from a focus on hardware to a focus on scientific data, TetraScience, led by veteran SaaS executive, Patrick Grady and Founder Spin Wang, has embarked on a journey from nearly cash-out to a player in the scientific data management space. This case... View Details
- October 2023 (Revised June 2024)
- Case
Catalent: Catalyzing the Next Era of Growth
By: Satish Tadikonda, William Marks and Kevin Emancipator
Catalent's newly appointed CEO, Alessandro Maselli, experienced the highs of the pharmaceutical contract development manufacturing (CDMO) space during COVID-19 while helping Moderna and others bring vaccines to market quickly and safely. After rushing to add capacity... View Details
- September 2023 (Revised December 2023)
- Case
TetraScience: Noise and Signal
By: Thomas R. Eisenmann and Tom Quinn
In 2019, TetraScience CEO “Spin” Wang needed advice. Five years earlier, he had cofounded a startup that saw early success with a hardware product designed to help laboratory scientists in the biotechnology and pharmaceutical spaces more easily collect data from... View Details
Keywords: Entrepreneurship; Business Growth and Maturation; Business Organization; Restructuring; Forecasting and Prediction; Digital Platforms; Analytics and Data Science; AI and Machine Learning; Organizational Structure; Network Effects; Competitive Strategy; Biotechnology Industry; Pharmaceutical Industry; United States; Boston