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    • All HBS Web  (325)
      • Faculty Publications  (21)

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      • September 2024
      • Article

      Standing on the Shoulders of Science

      By: Joshua Lev Krieger, Monika Schnitzer and Martin Watzinger
      Today’s innovations rely on scientific discoveries of the past, yet only some corporate R&D builds directly on scientific output. In this paper, we analyze U.S. patents to investigate how firms generate value by building on prior art “closer” to science. We show... View Details
      Keywords: Patent Novelty; Value Capture; Science; Patents; Valuation; Research and Development
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      Krieger, Joshua Lev, Monika Schnitzer, and Martin Watzinger. "Standing on the Shoulders of Science." Strategic Management Journal 45, no. 9 (September 2024): 1670–1695.
      • April 2024 (Revised December 2024)
      • Case

      Anthropic: Building Safe AI

      By: Shikhar Ghosh and Shweta Bagai
      In late 2024, Anthropic, a leading AI safety and research company, achieved a significant breakthrough with computer use capabilities that allowed AI to interact with computers like humans. Co-founded by former OpenAI employees and known for its generative AI... View Details
      Keywords: AI and Machine Learning; Corporate Accountability; Corporate Social Responsibility and Impact; Business Growth and Maturation; Corporate Strategy; Technology Industry; United States
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      Ghosh, Shikhar, and Shweta Bagai. "Anthropic: Building Safe AI." Harvard Business School Case 824-129, April 2024. (Revised December 2024.)
      • October–December 2023
      • Article

      A Practical Guide to Conversation Research: How to Study What People Say to Each Other

      By: Michael Yeomans, Katelynn Boland, Hanne K. Collins, Nicole Abi-Esber and Alison Wood Brooks
      Conversation—a verbal interaction between two or more people—is a complex, pervasive, and consequential human behavior. Conversations have been studied across many academic disciplines. However, advances in recording and analysis techniques over the last decade have... View Details
      Keywords: Interpersonal Communication; Analytics and Data Science; Research
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      Yeomans, Michael, Katelynn Boland, Hanne K. Collins, Nicole Abi-Esber, and Alison Wood Brooks. "A Practical Guide to Conversation Research: How to Study What People Say to Each Other." Advances in Methods and Practices in Psychological Science 6, no. 4 (October–December 2023).
      • April 5, 2023
      • Article

      We Need an Operation Warp Speed for Long COVID

      By: Esther K. Choo and Scott Duke Kominers
      With millions of people affected and at least $1 trillion of economic value at stake, long COVID is our next national health emergency. View Details
      Keywords: COVID; COVID-19; COVID-19 Pandemic; Scientific Research; Policy; Health Policy; Innovation; Science; Public Finance; Public Health; Health Disorders; Health Care and Treatment; Human Capital
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      Choo, Esther K., and Scott Duke Kominers. "We Need an Operation Warp Speed for Long COVID." Scientific American (website) (April 5, 2023).
      • March, 2023
      • Article

      Academic Entrepreneurship: Entrepreneurial Advisors and Their Advisees' Outcomes

      By: Maria P. Roche
      The transfer of complex knowledge and skills is difficult, often requiring intensive interaction and extensive periods of co-working between a mentor and mentee, which is particularly true in apprenticeship-like settings and on-the-job training. This paper studies a... View Details
      Keywords: Entrepreneurship; Higher Education; Training; Personal Development and Career; Knowledge Dissemination
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      Roche, Maria P. "Academic Entrepreneurship: Entrepreneurial Advisors and Their Advisees' Outcomes." Organization Science 34, no. 2 (March, 2023): 959–986.
      • April 27, 2022
      • Article

      Inequality in Researchers' Minds: Four Guiding Questions for Studying Subjective Perceptions of Economic Inequality

      By: Jon M. Jachimowicz, Shai Davidai, Daniela Goya-Tocchetto, Barnabas Szaszi, Martin Day, Stephanie Tepper, L. Taylor Phillips, M. Usman Mirza, Nailya Ordabayeva and Oliver P. Hauser
      Subjective perceptions of inequality can substantially influence policy attitudes, public health metrics, and societal well-being, but the lack of consensus in the scientific community on how to best operationalize and measure these perceptions may impede progress on... View Details
      Keywords: Equality and Inequality; Perception; Analysis
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      Jachimowicz, Jon M., Shai Davidai, Daniela Goya-Tocchetto, Barnabas Szaszi, Martin Day, Stephanie Tepper, L. Taylor Phillips, M. Usman Mirza, Nailya Ordabayeva, and Oliver P. Hauser. "Inequality in Researchers' Minds: Four Guiding Questions for Studying Subjective Perceptions of Economic Inequality." Journal of Economic Surveys (April 27, 2022).
      • April 12, 2022
      • Article

      Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States

      By: Estee Y. Cramer, Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li and et al.
      Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models... View Details
      Keywords: COVID-19; Forecasting and Prediction; Health Pandemics; Mathematical Methods; Partners and Partnerships
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      Cramer, Estee Y., Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li, and et al. "Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States." e2113561119. Proceedings of the National Academy of Sciences 119, no. 15 (April 12, 2022). (See full author list here.)
      • Article

      Measuring the Scientific Effectiveness of Contact Tracing: Evidence from a Natural Experiment

      By: Thiemo Fetzer and Thomas Graeber
      Contact tracing has for decades been a cornerstone of the public health approach to epidemics, including Ebola, severe acute respiratory syndrome, and now COVID-19. It has not yet been possible, however, to causally assess the method’s effectiveness using a randomized... View Details
      Keywords: COVID-19; Contact Tracing; Public Health; Infectious Diseases; Health Pandemics
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      Fetzer, Thiemo, and Thomas Graeber. "Measuring the Scientific Effectiveness of Contact Tracing: Evidence from a Natural Experiment." Proceedings of the National Academy of Sciences 118, no. 33 (August 17, 2021): 1–4.
      • May 2021
      • Case

      The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease

      By: Amitabh Chandra, Spencer Lee-Rey and Caroline Marra
      This case explores incentives for rare disease drug development by chronicling the role of the Spinal Muscular Atrophy (SMA) Foundation in forming strategic partnerships with the scientific research community and pharmaceutical developers to transform the trajectory... View Details
      Keywords: Innovation and Invention; Strategy; Business or Company Management; Society; Health; Public Administration Industry; Public Administration Industry; United States
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      Chandra, Amitabh, Spencer Lee-Rey, and Caroline Marra. "The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease." Harvard Business School Case 621-112, May 2021.
      • November 9, 2019
      • Article

      Effect of Revealing Authors' Conflicts of Interests in Peer Review: Randomized Controlled Trial

      By: Leslie K. John, George Loewenstein, Andrew Marder and Michael Callaham
      Objective: To assess the impact of disclosing authors’ conflict of interest declarations to peer reviewers at a medical journal.
      Design: Randomised controlled trial.

      Setting: The study was conducted within the manuscript review process at the... View Details
      Keywords: Conflicts Of Interest; Peer Review; Randomized Controlled Trial; Scientific Publication; Conflict of Interests; Journals and Magazines; Science
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      John, Leslie K., George Loewenstein, Andrew Marder, and Michael Callaham. "Effect of Revealing Authors' Conflicts of Interests in Peer Review: Randomized Controlled Trial." BMJ: British Medical Journal 367, no. 8221 (November 9, 2019).
      • 2018
      • Book

      Food Citizenship: Food System Advocates in an Era of Distrust

      By: Ray A. Goldberg
      The global food system is the largest segment of the world's economy. As agribusiness-studies pioneer Ray Goldberg suggests, it is also the largest health system on the planet. And it is changing fast. Its size and importance to human, environmental, and economic... View Details
      Keywords: Food; System; Global Range; Health; Environmental Sustainability; Development Economics; Partners and Partnerships; Public Opinion; Agriculture and Agribusiness Industry; Food and Beverage Industry
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      Goldberg, Ray A. Food Citizenship: Food System Advocates in an Era of Distrust. New York: Oxford University Press, 2018.
      • 2016
      • Book

      Building a Culture of Health: A New Imperative for Business

      By: John A. Quelch and Emily C. Boudreau
      This ambitious volume sets out to understand how every company impacts public health and introduces a robust model, rooted in organizational and scientific knowledge, for companies committed to making positive contributions to health and wellness. Focusing on four... View Details
      Keywords: Social Marketing; Corporate Social Responsibility and Impact; Health
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      Quelch, John A., and Emily C. Boudreau. Building a Culture of Health: A New Imperative for Business. SpringerBriefs in Public Health. Springer, 2016.
      • February 2016
      • Article

      Bridging Science and Technology Through Academic-Industry Partnerships

      By: Sen Chai and Willy C. Shih
      Partnerships that foster the translation of scientific advances emerging from academic research organizations into commercialized products at private firms are a policy tool that has attracted increased interest. This paper examines empirical data from the Danish... View Details
      Keywords: Economic Development; Technological Change; Government Policy; Technological Innovation; Research and Development; Information Technology; Policy; Technology Industry; Denmark
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      Chai, Sen, and Willy C. Shih. "Bridging Science and Technology Through Academic-Industry Partnerships." Research Policy 45, no. 1 (February 2016): 148–158.
      • 2014
      • Working Paper

      The Organizational and Geographic Drivers of Absorptive Capacity: An Empirical Analysis of Pharmaceutical R&D Laboratories

      By: Francesca Lazzeri and Gary P. Pisano
      Scholars and practitioners alike now recognize that a firm's capacity to assimilate and use know-how from external sources—what Cohen and Levinthal (1990) called "absorptive capacity"—plays a central role in innovation performance. In recent years, a common strategy... View Details
      Keywords: Geographic Location; Industry Clusters; Knowledge Acquisition; Pharmaceutical Industry; San Francisco; San Diego; Massachusetts
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      Lazzeri, Francesca, and Gary P. Pisano. "The Organizational and Geographic Drivers of Absorptive Capacity: An Empirical Analysis of Pharmaceutical R&D Laboratories." Harvard Business School Working Paper, No. 14-098, April 2014.
      • September 2013
      • Article

      Prizes, Publicity, and Patents: Non-Monetary Awards as a Mechanism to Encourage Innovation

      By: Petra Moser and Tom Nicholas
      This paper exploits the selection of prize-winning technologies among exhibitors at the Crystal Palace Exhibition in 1851 to examine whether—and how—ex post prizes that are awarded to high-quality innovations may encourage future innovation. U.S. patent data... View Details
      Keywords: Prizes; Innovation; Motivation and Incentives; Patents; Innovation and Invention
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      Moser, Petra, and Tom Nicholas. "Prizes, Publicity, and Patents: Non-Monetary Awards as a Mechanism to Encourage Innovation." Journal of Industrial Economics 61, no. 3 (September 2013): 763–788.
      • 2014
      • Working Paper

      Bridging Science and Technology Through Academic-Industry Partnerships

      By: Sen Chai and Willy C. Shih
      Scientific research and its translation into commercialized technology is a driver of wealth creation and economic growth. Partnerships to foster the translational processes from public research organizations, such as universities and hospitals, to private firms are a... View Details
      Keywords: Innovation; Firm Performance; Public-private Partnership Funding; Translational Research; Small And Medium Enterprises; Partners and Partnerships; Public Sector; Private Sector; Performance; Science-Based Business; Innovation and Invention
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      Chai, Sen, and Willy C. Shih. "Bridging Science and Technology Through Academic-Industry Partnerships." Harvard Business School Working Paper, No. 13-058, January 2013. (Revised July 2014.)
      • April 2012
      • Case

      Danish National Advanced Technology Foundation

      By: Willy Shih and Margaret Pierson
      Danish National Advanced Technology Foundation (DNATF), a government agency, invests in public-private partnerships to stimulate commercialization of Danish scientific research within the country's industry. DNATF established a process for evaluating proposals, making... View Details
      Keywords: Leadership; Commercialization; Management Practices and Processes; Experience and Expertise; Innovation and Invention; Public Ownership; Business and Government Relations; Technology Industry; Denmark
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      Shih, Willy, and Margaret Pierson. "Danish National Advanced Technology Foundation." Harvard Business School Case 612-091, April 2012.
      • July–August 2008
      • Article

      Interview with a Quality Leader: Regina E. Herzlinger on Consumer-Driven Healthcare

      By: Regina E. Herzlinger
      Regina E. Herzlinger is the Nancy R. McPherson Professor of Business Administration Chair at the Harvard Business School, Cambridge, MA. She received her bachelor's degree from MIT and her doctorate from the Harvard Business School The first woman to be tenured and... View Details
      Keywords: Consumer-driven Health Care; Health Care and Treatment; Health Industry
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      "Interview with a Quality Leader: Regina E. Herzlinger on Consumer-Driven Healthcare." Journal for Healthcare Quality 30, no. 4 (July–August 2008): 17–19.
      • May 2008 (Revised May 2008)
      • Case

      Symyx Technologies, Inc.

      By: H. Kent Bowen, Courtney Purrington and Thomas D. Perry
      Symyx is a science-based company spun out of Berkeley. Its unique materials technology has been exploited for 10 years, but the company needs a new business model. The company concept required the invention of hardware and software to do high throughput materials... View Details
      Keywords: Business Model; Transition; Engineering; Technological Innovation; Resource Allocation; Product Development; Partners and Partnerships; Science-Based Business; Information Infrastructure; Applications and Software
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      Bowen, H. Kent, Courtney Purrington, and Thomas D. Perry. "Symyx Technologies, Inc." Harvard Business School Case 608-152, May 2008. (Revised May 2008.)
      • Forthcoming
      • Article

      How Important Is Editorial Gatekeeping? Evidence from Top Biomedical Journals

      By: Joshua L. Krieger, Kyle R. Myers and Ariel D. Stern
      We examine editors' influence on the scientific content of academic journals by unpacking the role of three major forces: journals' missions, aggregate supply of and demand for specific topics, and scientific homophily via editorial gatekeeping. In a sample of top... View Details
      Keywords: Editors; Biomedical Research; Editorial Gatekeeping; Scientific Homophily; Intellectual Capital; Mission and Purpose; Journals and Magazines; Intellectual Property; Innovation and Invention; Human Capital; Higher Education; Publishing Industry
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      Krieger, Joshua L., Kyle R. Myers, and Ariel D. Stern. "How Important Is Editorial Gatekeeping? Evidence from Top Biomedical Journals." Review of Economics and Statistics (forthcoming). (Pre-published online May 29, 2023.)
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