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- 27 Aug 2008
- Research & Ideas
Creating Leaders for Science-Based Businesses
Education offerings that teach scientists business and organizational fundamentals? What about joint MBA/Ph.D. programs? How about science/business seminars, more science-based cases, and more science-savvy... View Details
- March 2008
- Case
Novartis AG: Science-Based Business
By: H. Kent Bowen and Courtney Purrington
Novartis is a science-based drug company, which has important implications for its business strategy. It is one of the largest pharmaceutical companies in the world with over $38B in sales in 2007. Pharmaceuticals account for slightly over $24B of that total. In 2007,... View Details
Keywords: Innovation and Invention; Resource Allocation; Product Development; Partners and Partnerships; Research and Development; Science-Based Business; Pharmaceutical Industry
Bowen, H. Kent, and Courtney Purrington. "Novartis AG: Science-Based Business." Harvard Business School Case 608-136, March 2008.
- April 2012 (Revised May 2012)
- Case
Merck: Operating Science-Based Business
By: Ananth Raman, Inga Maurer and William Schmidt
Merck is known for its commitment to investing in basic R&D. Are Merck's long-term investments justifiable when the firm faces extreme earnings pressure? View Details
Keywords: Science-Based Business; Management; Research and Development; Business and Shareholder Relations; Operations; Pharmaceutical Industry; United States
Raman, Ananth, Inga Maurer, and William Schmidt. "Merck: Operating Science-Based Business." Harvard Business School Case 612-082, April 2012. (Revised May 2012.)
- Research Summary
Science-Based Business and the Business of Science
By: H. Kent Bowen
Science and technology can provide strategic advantage to companies' through differentiated products and processes. The focus of our research is on unusually productive and creative labs that are the sources of breakthroughs that create platforms for sustained... View Details
- Research Summary
Industrial competitiveness in high tech and science-based businesses
By: Willy C. Shih
How do emerging economies develop industrial and technical capabilities that overtake those of advanced economies? Are there some industrial sectors that are especially susceptible to such targeting? What will it take to restore America’s... View Details
- September 2010
- Case
Merck: Investing in Science-Based Business (Abridged)
By: Ananth Raman and Inga Katharina Maurer
Ray Gilmartin faces a dilemma. His company's credibility has been damaged by the recent withdrawal of Vioxx, a multi-billion dollar drug. Moreover, the withdrawal of Vioxx would imply that Merck would fail to meet analysts' earnings expectations for 2005 unless... View Details
Raman, Ananth, and Inga Katharina Maurer. "Merck: Investing in Science-Based Business (Abridged)." Harvard Business School Case 611-027, September 2010.
- 01 Jun 2009
- Lessons from the Classroom
The Challenges of Investing in Science-Based Innovation
In economic downtimes, businesses are apt to cut R&D projects that don't promise a speedy return on investment. But take a cue from smart science-based businesses, which view the recession as an... View Details
- 19 Feb 2010
- Working Paper Summaries
The Evolution of Science-Based Business: Innovating How We Innovate
Keywords: by Gary P. Pisano
- Article
The Evolution of Science-Based Business: Innovating How We Innovate
By: Gary P. Pisano
Science has long been connected to innovation and to business. As early as the late 19th century, chemical companies, realizing the commercial potential of science, created the first industrial research laboratories. During much of the 20th century, large-scale... View Details
Keywords: Entrepreneurship; Governance; Innovation and Management; Risk Management; Research and Development; Science-Based Business; Commercialization
Pisano, Gary P. "The Evolution of Science-Based Business: Innovating How We Innovate." Special Issue on Management Innovation—Essays in the Spirit of Alfred D. Chandler. Industrial and Corporate Change 19, no. 2 (April 2010): 465–482.
- 2022
- Article
Science-based Entrepreneurship in India: A Policy Glass (as yet) Quarter-Full
By: Tarun Khanna
India is celebrated for a resurgence of de novo entrepreneurship in recent decades. Entrants have engaged in creative risk-taking to provide market-based solutions for private or social needs despite not being scions of wealthy industrial or business families. In this... View Details
Khanna, Tarun. "Science-based Entrepreneurship in India: A Policy Glass (as yet) Quarter-Full." India Policy Forum 19 (2022): 1–53.
- September 2013 (Revised November 2015)
- Case
Living Proof: Are We a Technology Company or a Beauty Company?
By: Willy Shih
Jon Flint came up with the idea of a science-based beauty company while talking with his hairdresser about the problems with typical hair and skin care products. Together with a small team that included Professor Robert Langer of MIT, he committed to assemble a team... View Details
Keywords: Hair Care; Personal Care; Science-based; R＆D; Innovation and Invention; Innovation and Management; Innovation Leadership; Innovation Strategy; Technological Innovation; Marketing; Marketing Strategy; Product Marketing; Product Positioning; Science-Based Business; Business Strategy; Commercialization; Corporate Strategy; Technology Platform; Expansion; Beauty and Cosmetics Industry; United States; Boston; Cambridge
Shih, Willy. "Living Proof: Are We a Technology Company or a Beauty Company?" Harvard Business School Case 614-013, September 2013. (Revised November 2015.)
- Winter 2017
- Article
Why Big Data Isn't Enough
By: Sen Chai and Willy C. Shih
There is a growing belief that sophisticated algorithms can explore huge databases and find relationships independent of any preconceived hypotheses. But in businesses that involve scientific research and technological innovation, this approach is misguided and... View Details
Keywords: Big Data; Science-based; Science; Scientific Research; Data Analytics; Data Science; Data-driven Management; Data Scientists; Technological Innovation; Analytics and Data Science; Mathematical Methods; Theory
Chai, Sen, and Willy C. Shih. "Why Big Data Isn't Enough." Art. 58227. MIT Sloan Management Review 58, no. 2 (Winter 2017): 57–61.
- 13 Sep 2021
- Research & Ideas
Science: The Unlikely Frontier for New Business Ideas
million—more value to companies than patented inventions developed without citing scientific research, says a paper co-authored by Harvard Business School professor Joshua Lev Krieger, University of Munster professor Martin Watzinger, and... View Details
Keywords: by Avery Forman
- January 2020
- Background Note
Climate Change in 2020: Implications for Business
By: Rebecca M. Henderson, Sophus A. Reinert and Mariana Oseguera
This note provides general information about climate change and its implications for business. Included is an overview of climate change science and a number of its impacts, including rising sea levels, changing weather patterns and extreme weather, pressure on water... View Details
Keywords: Climate Change; Environmental Accounting; Agribusiness; Economic Growth; Energy Conservation; Energy Generation; Renewable Energy; Energy Sources; Non-Renewable Energy; Globalized Markets and Industries; National Security; Government Legislation; Operations; Corporate Social Responsibility and Impact; Problems and Challenges; Risk and Uncertainty; Natural Disasters; Natural Environment; Environmental Sustainability; Pollutants; Science-Based Business; Weather; Society; Technology
Henderson, Rebecca M., Sophus A. Reinert, and Mariana Oseguera. "Climate Change in 2020: Implications for Business." Harvard Business School Background Note 320-087, January 2020. (Click here for a complimentary copy on the Business & Environment Initiative’s site.)
- 2001
- Chapter
A Business Manager's Approach to Climate Change
By: Forest Reinhardt and Kimberly O'Neill Packard
Reinhardt, Forest, and Kimberly O'Neill Packard. "A Business Manager's Approach to Climate Change." In Climate Change: Science, Strategies, & Solutions, edited by Eileen Claussen. Leiden: Brill Academic Publishers, 2001.
- March 2019
- Case
DayTwo: Going to Market with Gut Microbiome
By: Ayelet Israeli and David Lane
DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
Keywords: Start-up Growth; Startup; Positioning; Targeting; Go To Market Strategy; B2B2C; B2B Vs. B2C; Health ＆ Wellness; AI; Machine Learning; Female Ceo; Female Protagonist; Science-based; Science And Technology Studies; Ecommerce; Applications; DTC; Direct To Consumer Marketing; US Health Care; ＂USA,＂; Innovation; Pricing; Business Growth; Segmentation; Distribution Channels; Growth and Development Strategy; Business Startups; Science-Based Business; Health; Innovation and Invention; Marketing; Information Technology; Business Growth and Maturation; E-commerce; Applications and Software; Health Industry; Technology Industry; Insurance Industry; Information Technology Industry; Food and Beverage Industry; Israel; United States
Israeli, Ayelet, and David Lane. "DayTwo: Going to Market with Gut Microbiome." Harvard Business School Case 519-010, March 2019.
- November 2020
- Teaching Note
DayTwo: Going to Market with Gut Microbiome
By: Ayelet Israeli
Teaching Note for HBS Case No. 519-010. DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals.... View Details
Keywords: Start-up Growth; Startup; Positioning; Targeting; Go To Market Strategy; B2B Vs. B2C; B2B2C; Health ＆ Wellness; AI; Machine Learning; Female Ceo; Female Protagonist; Science-based; Science And Technology Studies; Ecommerce; Applications; DTC; Direct To Consumer Marketing; US Health Care; ＂USA,＂; Innovation; Pricing; Business Growth; Segmentation; Distribution Channels; Growth and Development Strategy; Business Startups; Science-Based Business; Health; Innovation and Invention; Marketing; Information Technology; Business Growth and Maturation; E-commerce; Applications and Software; Health Industry; Technology Industry; Insurance Industry; Information Technology Industry; Food and Beverage Industry; Israel; United States
- May 2008 (Revised May 2008)
- Case
Symyx Technologies, Inc.
By: H. Kent Bowen, Courtney Purrington and Thomas D. Perry
Symyx is a science-based company spun out of Berkeley. Its unique materials technology has been exploited for 10 years, but the company needs a new business model. The company concept required the invention of hardware and software to do high throughput materials... View Details
Keywords: Business Model; Transition; Engineering; Technological Innovation; Resource Allocation; Product Development; Partners and Partnerships; Science-Based Business; Information Infrastructure; Applications and Software
Bowen, H. Kent, Courtney Purrington, and Thomas D. Perry. "Symyx Technologies, Inc." Harvard Business School Case 608-152, May 2008. (Revised May 2008.)
- May 2003 (Revised June 2003)
- Case
Revitalizing Philips (A)
Philips is a major science-based multinational that has been restructuring since the early 1970s. This case provides an historical perspective on earlier efforts as well as a detailed description of the one pursued under Cor Boonstra, CEO from 1996 to 2001, that... View Details
Ghemawat, Pankaj, and Pedro Nueno. "Revitalizing Philips (A)." Harvard Business School Case 703-501, May 2003. (Revised June 2003.)
- January 2017 (Revised December 2017)
- Case
Carmichael Roberts: To Create a Private Equity Firm?
By: Steven Rogers and Kenneth J. Cooper
Carmichael Roberts, a rare African-American venture capitalist, considered leaving his general partnership in a private equity firm near Boston and setting up his own in 2015. He weighed whether the timing was right, with the economy still not fully recovered from the... View Details
Keywords: Venture Capital; Equity; Innovation And Invention; Investment; Ownership; Science; Science Bassed Business; Markets; Relationships; Capital; Private Equity; Technological Innovation; Investment Return; Going Public; Ownership Stake; Science-Based Business; Market Timing; Marketplace Matching; Partners and Partnerships; Financial Services Industry; Technology Industry; Manufacturing Industry; United States; Massachusetts; Boston; California; San Francisco; New York (city, NY)
Rogers, Steven, and Kenneth J. Cooper. "Carmichael Roberts: To Create a Private Equity Firm?" Harvard Business School Case 317-079, January 2017. (Revised December 2017.)