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- May 2025 (Revised May 2025)
- Background Note
Social Enterprise in Latin America
By: Brian L. Trelstad and Karina Souza
This research note provides an overview of the social enterprise ecosystem in Latin America, exploring current dynamics across key markets, including country-specific insights on Brazil, Mexico, Argentina, Colombia, Chile, and Central America. In a region characterized... View Details
Keywords: Latin America; Brazil; Mexico; Argentina; Colombia; Chile; Impact Investing; Developing Countries and Economies; Social Entrepreneurship; Emerging Markets; Corporate Social Responsibility and Impact; Mission and Purpose; Ownership; Social Enterprise; Business Strategy; Equality and Inequality; Information Technology Industry; Information Technology Industry; Information Technology Industry; Information Technology Industry; Latin America; Brazil; Mexico; Argentina; Colombia; Chile; Guatemala; Central America
- April 2025
- Case
Breezm: Innovative 3D-Printed Eyewear (A)
By: Juan Alcácer, Brian Mao Fu and Adina Wong
In 2023, Breezm, a South Korean startup, faced a strategic decision about how to grow its innovative 3D-printed, custom-fit eyewear business. Co-founded in 2017 by Zenma Park and Wooseok Sung, Breezm combined facial scanning, AI, and in-house production to solve the... View Details
Keywords: 3D Printing; Eyeyewear; Growth; Business Startups; AI and Machine Learning; Technological Innovation; Growth and Development Strategy; Risk and Uncertainty; Expansion; South Korea
Alcácer, Juan, Brian Mao Fu, and Adina Wong. "Breezm: Innovative 3D-Printed Eyewear (A)." Harvard Business School Case 725-376, April 2025.
- 2025
- Working Paper
Blockchain-Induced Supply Chain Transparency and Firm Performance: The Role of Capacity Utilization
By: ShinWoo Lee Lee, Jedson Pinto, Daniel Rabetti and Gil Sadka
This study empirically investigates how blockchain adoption affects firm profitability. Employing a quasi-experimental design triggered by regulatory changes across the United States, we provide novel empirical evidence to recent theory, proposing that blockchain... View Details
Keywords: Blockchain; Supply Chain; Technology Adoption; Profit; Governing Rules, Regulations, and Reforms; United States
Lee, ShinWoo Lee, Jedson Pinto, Daniel Rabetti, and Gil Sadka. "Blockchain-Induced Supply Chain Transparency and Firm Performance: The Role of Capacity Utilization." Working Paper, February 2025.
- 2025
- Working Paper
Blockchain Adoption and Audit Quality
By: Mei Luo, Daniel Rabetti and Shuangchen Yu
This study examines the impact of blockchain adoption in the corporate setting. Specifically, we provide comprehensive empirical support to recent theory (Cao, Cong, and Young, 2024) proposing that blockchain adoption positively affects endogenous audit quality and... View Details
Keywords: Blockchain; Accounting Audits; Technology Adoption; Financial Reporting; Governing Rules, Regulations, and Reforms; China
Luo, Mei, Daniel Rabetti, and Shuangchen Yu. "Blockchain Adoption and Audit Quality." Working Paper, February 2025.
- February 2025
- Article
Disclosure, Humanizing, and Contextual Vulnerability of Generative AI Chatbots
By: Julian De Freitas and I. Glenn Cohen
In the wake of recent advancements in generative AI, regulatory bodies are trying to keep pace. One key decision is whether to require app makers to disclose the use of generative AI-powered chatbots in their products. We suggest that some generative AI-based chatbots... View Details
Keywords: AI and Machine Learning; Governing Rules, Regulations, and Reforms; Applications and Software; Well-being
De Freitas, Julian, and I. Glenn Cohen. "Disclosure, Humanizing, and Contextual Vulnerability of Generative AI Chatbots." New England Journal of Medicine AI 2, no. 2 (February 2025).
- January 2025
- Teaching Note
Vytal: Packaging-as-a-Service
By: George Serafeim, Michael W. Toffel and Stacy Straaberg
Teaching Note for HBS Case No. 124-007. The Germany-based startup Vytal operated the largest digital-native reusable packaging-as-a-service network globally, having raised nearly €15 million, established a large network of restaurant partners, and prevented the use of... View Details
Keywords: Environmental Sustainability; Innovation and Invention; Business Growth and Maturation; Growth and Development Strategy; Business Startups; Resource Allocation; Risk Management; Adoption; Strategy; Performance Productivity; Service Delivery; Service Operations; Supply Chain; Distribution; Entrepreneurship; Climate Change; Business Model; Governing Rules, Regulations, and Reforms; Profit; Financing and Loans; Expansion; Green Technology Industry; Green Technology Industry; Green Technology Industry; Germany; Europe
- January 2025
- Article
Enterprise Resource Planning (ERP) System Implementations and Corporate Misconduct
By: Jonas Heese and Joseph Pacelli
This study examines whether enterprise resource planning (ERP) implementations are associated with reductions in corporate misconduct. Specifically, we study the relation between staggered facility-level rollouts of ERP systems and facility-level regulatory violations... View Details
Heese, Jonas, and Joseph Pacelli. "Enterprise Resource Planning (ERP) System Implementations and Corporate Misconduct." Accounting Review 100, no. 1 (January 2025): 291–315.
- November 2024
- Teaching Note
Mercado Bitcoin: M&A, IPO, or Series B?
By: Raymond Kluender, Emanuele Colonnelli and Sabrina Howell
Teaching Note for HBS Case No. 825-047. In April 2021, Brazilian cryptocurrency platform Mercado Bitcoin, had to decide how to scale: go public, M&A with a bank, or take a VC big check. In a highly volatile market, Roberto Dagnoni, chairman of the board, viewed the... View Details
Keywords: Cryptocurrency; Mergers and Acquisitions; Business Growth and Maturation; Business Startups; Decision Making; Going Public; Ownership Stake; Strategic Planning; Venture Capital; Problems and Challenges; Business Cycles; Digital Platforms; Emerging Markets; Market Timing; Expansion; Diversification; Valuation; Value Creation; Investment Funds; Initial Public Offering; Price; Price Bubble; Negotiation Offer; Information Technology Industry; Information Technology Industry; Brazil; Latin America
- 2024
- Working Paper
Why Has Construction Productivity Stagnated? The Role of Land-Use Regulation
By: Leonardo D’Amico, Edward Glaeser, Joseph Gyourko, William Kerr and Giacomo A. M. Ponzetto
We document a Kuznets curve for construction productivity in 20th-century America.
Homes built per construction worker remained stagnant between 1900 and 1940, boomed after
World War II, and then plummeted after 1970. The productivity boom from 1940 to 1970
shows... View Details
D’Amico, Leonardo, Edward Glaeser, Joseph Gyourko, William Kerr, and Giacomo A. M. Ponzetto. "Why Has Construction Productivity Stagnated? The Role of Land-Use Regulation." Harvard Business School Working Paper, No. 25-027, November 2024.
- 2024
- Working Paper
Climate Solutions, Transition Risk, and Stock Returns
By: Shirley Lu, Edward J. Riedl, Simon Xu and George Serafeim
Using large language models to measure firms' climate solution products and services, we find that high-climate solution firms exhibit lower stock returns and higher market valuation multiples. Their stock prices respond positively to events signaling increased demand... View Details
Keywords: Technology; Generative Ai; Large Language Models; Climate Finance; Climate Change; Innovation and Invention; Environmental Sustainability; AI and Machine Learning; Investment; Financial Markets
Lu, Shirley, Edward J. Riedl, Simon Xu, and George Serafeim. "Climate Solutions, Transition Risk, and Stock Returns." Harvard Business School Working Paper, No. 25-024, November 2024.
- October 2024
- Case
Tonik
By: Andy Wu, Maliha Malek Quadir and Aticus Peterson
This case study examines Tonik, the first digital bank in the Philippines, as it navigates the challenges of scaling its lending operations and achieving profitability in an evolving fintech landscape. It explores Tonik's journey from its launch in 2018 to early 2024,... View Details
- September 2024 (Revised March 2025)
- Case
Epic: The Future of Health Information Technology
By: Regina E. Herzlinger and Brian L. Walker
How should the founder and leadership team of a health IT company with more than 45 years of market leadership prepare for the future, while navigating founder transitions and industry changes? Founded by Judy Faulkner in the late 1970s, Epic pioneered electronic... View Details
Keywords: Technological Innovation; Entrepreneurship; Health Care and Treatment; Private Ownership; Customer Focus and Relationships; Information Management; Organizational Change and Adaptation; Business Strategy; Competition; Information Technology Industry; Information Technology Industry; Information Technology Industry
Herzlinger, Regina E., and Brian L. Walker. "Epic: The Future of Health Information Technology." Harvard Business School Case 325-028, September 2024. (Revised March 2025.)
- August 2024
- Case
Iogen: Decarbonizing Hard-to-Abate Sectors
By: George Serafeim, Charlotte Foody and John Mulliken
Brian Foody, CEO of Iogen Corporation, was an early leader in advanced biofuels, developing a range of technologies to transform agricultural waste into transportation fuel. With $100 million in revenue and 350 patents across various biofuel technologies, Iogen was... View Details
Keywords: Technology; Biofuel; Market Attractiveness; Decarbonization; Technological Innovation; Climate Change; Energy; Environmental Sustainability; Transformation; Market Entry and Exit; Strategy; Energy Industry; United States; United Kingdom
Serafeim, George, Charlotte Foody, and John Mulliken. "Iogen: Decarbonizing Hard-to-Abate Sectors." Harvard Business School Case 125-037, August 2024.
- August 2024 (Revised November 2024)
- Case
Mercado Bitcoin: M&A, IPO, or Series B?
By: Raymond Kluender, Emanuele Colonnelli, Sabrina T. Howell and Karina Souza
In April 2021, Brazilian cryptocurrency platform Mercado Bitcoin had to decide how to scale: go public, M&A with a bank, or take a VC big check. In a highly volatile market, Roberto Dagnoni, chairman of the board, viewed the unprecedent crypto momentum as a window of... View Details
Keywords: Cryptocurrency; Mergers and Acquisitions; Business Growth and Maturation; Business Startups; Decision Making; Going Public; Ownership Stake; Strategic Planning; Venture Capital; Problems and Challenges; Business Cycles; Digital Platforms; Emerging Markets; Market Timing; Expansion; Diversification; Valuation; Value Creation; Investment Funds; Initial Public Offering; Price; Price Bubble; Negotiation Offer; Financial Liquidity; Information Technology Industry; Information Technology Industry; Latin America; South America; Brazil; Sao Paulo; United States
Kluender, Raymond, Emanuele Colonnelli, Sabrina T. Howell, and Karina Souza. "Mercado Bitcoin: M&A, IPO, or Series B?" Harvard Business School Case 825-047, August 2024. (Revised November 2024.)
- June 2024 (Revised March 2025)
- Case
Wemade: (Re)Establishing Trust in Blockchain Games (A)
By: Jung Koo Kang, Charles C.Y. Wang, David Allen and Kwangmoon So
This case explores the fundamental challenges and accounting issues arising from the integration of blockchain technology into traditional business models. It features Wemade, a South Korean online gaming company that has staked its future on blockchain-based games.... View Details
Keywords: Blockchain; Cryptocurrency; Video Games; Accounting; Financial Reporting; Revenue Recognition; Games, Gaming, and Gambling; Corporate Disclosure; Information Technology; Technology Adoption; Information Technology Industry; Information Technology Industry; Information Technology Industry; South Korea
Kang, Jung Koo, Charles C.Y. Wang, David Allen, and Kwangmoon So. "Wemade: (Re)Establishing Trust in Blockchain Games (A)." Harvard Business School Case 124-025, June 2024. (Revised March 2025.)
- May 2024
- Article
The Health Risks of Generative AI-Based Wellness Apps
By: Julian De Freitas and G. Cohen
Artifcial intelligence (AI)-enabled chatbots are increasingly being used to
help people manage their mental health. Chatbots for mental health and
particularly ‘wellness’ applications currently exist in a regulatory ‘gray area’.
Indeed, most generative AI-powered... View Details
Keywords: AI and Machine Learning; Well-being; Governing Rules, Regulations, and Reforms; Applications and Software
De Freitas, Julian, and G. Cohen. "The Health Risks of Generative AI-Based Wellness Apps." Nature Medicine 30, no. 5 (May 2024): 1269–1275.
- March 2024
- Case
Nomad: A License to Bank
By: Paul A. Gompers and Pedro Levindo
In late 2023, Lucas Vargas, CEO and co-founder of Nomad, a fintech that offered financial services in the United States for Brazilian residents, had to decide what to do to ensure the company’s continued expansion. Nomad launched its first product, a U.S. digital bank... View Details
Keywords: Mergers and Acquisitions; Business Startups; Customer Satisfaction; Decision Making; Entrepreneurship; Banks and Banking; Initial Public Offering; Global Strategy; Growth and Development Strategy; Brands and Branding; Marketing Strategy; Product Launch; Organizational Culture; Going Public; Ownership Stake; Innovation and Invention; Strategic Planning; Business and Government Relations; Business and Stakeholder Relations; Risk and Uncertainty; Business Strategy; Competitive Advantage; Corporate Strategy; Diversification; Expansion; Vertical Integration; Leadership; Law; Technology Industry; Technology Industry; Technology Industry; Brazil; United States; North America; Latin America
Gompers, Paul A., and Pedro Levindo. "Nomad: A License to Bank." Harvard Business School Case 824-144, March 2024.
- February 26, 2024
- Article
Making Workplaces Safer Through Machine Learning
By: Matthew S. Johnson, David I. Levine and Michael W. Toffel
Machine learning algorithms can dramatically improve regulatory effectiveness. This short article describes the authors' scholarly work that shows how the U.S. Occupational Safety and Health Administration (OSHA) could have reduced nearly twice as many occupational... View Details
Keywords: Government Experimentation; Auditing; Inspection; Evaluation; Process Improvement; Government Administration; AI and Machine Learning; Safety; Governing Rules, Regulations, and Reforms
Johnson, Matthew S., David I. Levine, and Michael W. Toffel. "Making Workplaces Safer Through Machine Learning." Regulatory Review (February 26, 2024).
- January 2024
- Case
Fusion Industry Association: Igniting the Future of Clean Energy
Fusion energy is evolving from a scientific idea to a commercial possibility, drawing large investments and regulatory discussions; how should the FIA navigate this evolution?
The Fusion Industry Association (FIA) is at the forefront of transforming fusion... View Details
The Fusion Industry Association (FIA) is at the forefront of transforming fusion... View Details
Keywords: Science-Based Business; Engineering; Venture Capital; Entrepreneurship; Government and Politics; Government Legislation; Industry Clusters; Industry Growth; Industry Structures; Technological Innovation; Energy Industry; United States
Krieger, Joshua Lev, Jim Matheson, Kyle R. Myers, and Henry Tao. "Fusion Industry Association: Igniting the Future of Clean Energy." Harvard Business School Case 624-064, January 2024.
- January 2024 (Revised April 2024)
- Case
Target Malaria: Editing Mosquitoes through Gene Drives
By: Shikhar Ghosh and Shweta Bagai
Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details
Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa
Ghosh, Shikhar, and Shweta Bagai. "Target Malaria: Editing Mosquitoes through Gene Drives." Harvard Business School Case 824-068, January 2024. (Revised April 2024.)