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  • All HBS Web  (45)
    • Research  (43)
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  • All HBS Web  (45)
    • Research  (43)
  • Faculty Publications  (43)
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  • November 2016 (Revised December 2016)
  • Supplement

Anthony Starks at InSiL Therapeutics (B)

By: Vicki Sato and Gary Pisano
This case accompanies the (A) case from Anthony Starks's perspective. View Details
Keywords: Biotech; Management Challenges; R&D; R&D Project Management; Management; Biotechnology Industry; California
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Sato, Vicki, and Gary Pisano. "Anthony Starks at InSiL Therapeutics (B)." Harvard Business School Supplement 617-030, November 2016. (Revised December 2016.)
  • June 21, 2019
  • Article

Government-Funded Research Increasingly Fuels Innovation

By: Lee Fleming, Hillary Greene, Guan-Cheng Li, Matt Marx and Dennis Yao
Keywords: Innovation; R&D; Patents
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Fleming, Lee, Hillary Greene, Guan-Cheng Li, Matt Marx, and Dennis Yao. "Government-Funded Research Increasingly Fuels Innovation." Science 364, no. 6646 (June 21, 2019): 1139–1141.
  • November 2016
  • Case

Transformation at Eli Lilly & Co. (A)

By: William R. Kerr and Alexis Brownell
Faced with the imminent loss of 40% of its revenues due to patent expirations, pharma giant Eli Lilly sets out on a dramatic transformation process in 2009. The case considers how Lilly restructured the organization into business areas to aid better decision-making,... View Details
Keywords: Eli Lilly; Restructuring; R&D; Transformation; Organizational Change and Adaptation; Organizational Structure; Pharmaceutical Industry; Indianapolis
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Kerr, William R., and Alexis Brownell. "Transformation at Eli Lilly & Co. (A)." Harvard Business School Case 817-070, November 2016.
  • July 2022
  • Article

Estimating Spillovers from Publicly Funded R&D: Evidence from the US Department of Energy

By: Kyle Myers and Lauren Lanahan
We quantify the magnitude of R&D spillovers created by grants to small firms from the US Department of Energy. Our empirical strategy leverages variation due to state-specific matching policies, and we develop a new approach to measuring both geographic and... View Details
Keywords: Innovation; Energy; R&D; Grants; Innovation and Invention; Research and Development; Patents; Performance; United States
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Myers, Kyle, and Lauren Lanahan. "Estimating Spillovers from Publicly Funded R&D: Evidence from the US Department of Energy." American Economic Review 112, no. 7 (July 2022): 2393–2423.
  • March 2013
  • Article

Misvaluing Innovation

By: Lauren Cohen, Karl Diether and Christopher Malloy
We demonstrate that a firm's ability to innovate is predictable, persistent, and relatively simple to compute, and yet the stock market ignores the implications of past successes when valuing future innovation. We show that two firms that invest the exact same in... View Details
Keywords: Innovation; Return Predictability; R&D; Information; Forecasting and Prediction; Research and Development; Innovation and Invention
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Cohen, Lauren, Karl Diether, and Christopher Malloy. "Misvaluing Innovation." Review of Financial Studies 26, no. 3 (March 2013): 635–666.
  • May 2025
  • Article

The Diffusion of New Technologies

By: Aakash Kalyani, Marcela Carvalho, Nicholas Bloom, Tarek Hassan, Josh Lerner and Ahmed Tahoun
We identify phrases associated with novel technologies using textual analysis of patents, job postings, and earnings calls, enabling us to identify four stylized facts on the diffusion of jobs relating to new technologies. First, the development of economically... View Details
Keywords: Technology; Geography; Innovation; R&D; Technological Innovation; Research and Development; Employment; Geographic Location
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Kalyani, Aakash, Marcela Carvalho, Nicholas Bloom, Tarek Hassan, Josh Lerner, and Ahmed Tahoun. "The Diffusion of New Technologies." Quarterly Journal of Economics 140, no. 2 (May 2025): 1299–1365. (Earlier version distributed as National Bureau of Economic Research Working Paper No. 28999 and Harvard Business School Working Paper No. 21-114. Related discussion published as “How Disruptive Technologies Diffuse,” VoxEU, 2021.)
  • 2013
  • Working Paper

Did Bank Distress Stifle Innovation During the Great Depression?

By: Ramana Nanda and Tom Nicholas
We find a negative relationship between bank distress and the level, quality and trajectory of firm-level innovation during the Great Depression, particularly for R&D firms operating in capital intensive industries. However, we also show that because a sufficient... View Details
Keywords: Great Depression; R&D; Bank Distress; Patents; Research and Development; Financial Crisis; Innovation and Invention; Banks and Banking; Banking Industry; United States
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Nanda, Ramana, and Tom Nicholas. "Did Bank Distress Stifle Innovation During the Great Depression?" Harvard Business School Working Paper, No. 12-106, May 2012. (Revised October 2013. Revise and Resubmit, Journal of Financial Economics.)
  • October 2005
  • Column

Neology, La primera empresa mexicana productora de RFID, va al NASDAQ

By: Roberto Charvel
Keywords: R&D; Technological And Scientific Innovation; Innovation and Invention; Strategic Planning; Latin America
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Charvel, Roberto. "Neology, La primera empresa mexicana productora de RFID, va al NASDAQ." Investment Comments. Inbound Logistics LatAm 1, no. 9 (October 2005).
  • February 2014
  • Case

GSK Sets the Stage for Sustainability in Singapore

By: Vicki L. Sato, Rich Ballenger, Sen Chai, Ross Leimberg and Mariana Mihalusova
Keywords: Pharmaceutical Industry; International Business; R&D; Singapore
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Sato, Vicki L., Rich Ballenger, Sen Chai, Ross Leimberg, and Mariana Mihalusova. "GSK Sets the Stage for Sustainability in Singapore." Harvard Business School Case 614-053, February 2014.
  • Article

Did Bank Distress Stifle Innovation During the Great Depression?

By: Ramana Nanda and Tom Nicholas
We find a negative relationship between bank distress and the level, quality, and trajectory of firm-level innovation during the Great Depression, particularly for R&D firms operating in capital intensive industries. However, we also show that because a sufficient... View Details
Keywords: Great Depression; R&D; Bank Distress; Patents; Research and Development; Financial Crisis; Banks and Banking; Innovation and Invention; Banking Industry; United States
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Nanda, Ramana, and Tom Nicholas. "Did Bank Distress Stifle Innovation During the Great Depression?" Journal of Financial Economics 114, no. 2 (November 2014): 273–292.
  • June 2012 (Revised July 2012)
  • Case

Business-driven Research at IBM Research India

By: Willy Shih, Margaret Pierson, Pankaj Agarwal, Diego Medicina and Juan Prajogo
What is the right mix between business-driven and pure research? This case considers the question in the setting of IBM Research India, where a management push for balance between exploratory research and the fulfillment of business needs meets some resistance from... View Details
Keywords: R&D; Computer Services Industries; IT R&D; Internet; Web-enabled Application; Technological Planning; Emerging Technologies; Information Technology; Internet and the Web; Research and Development; Projects; Practice; India
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Shih, Willy, Margaret Pierson, Pankaj Agarwal, Diego Medicina, and Juan Prajogo. "Business-driven Research at IBM Research India ." Harvard Business School Case 612-076, June 2012. (Revised July 2012.)
  • October 2012 (Revised February 2014)
  • Teaching Note

Logoplaste: Global Growing Challenges (TN)

By: Juan Alcacer
The case follows Logoplaste in its transformation from a small player in the plastic container industry in Portugal to a mid-sized global firm with operations in 11 countries. The case summarizes Logoplaste's history, with an emphasis on the milestones of its global... View Details
Keywords: R&D; Innovation; Competitive Advantage; Operations Strategy; Global Strategy; Competition; Operations; Strategy; Manufacturing Industry
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Alcacer, Juan. "Logoplaste: Global Growing Challenges (TN)." Harvard Business School Teaching Note 713-446, October 2012. (Revised February 2014.)
  • 2023
  • Working Paper

Leadership and the Value of Persistence

By: James J. Anton, Alan Jaske and Dennis Yao
Consider a leader’s decision whether to persist with an unsuccessful R&D project or to terminate the project in favor of a new project with an uncertain value. How does that decision affect the effort exerted by the manager assigned to the project? To study this... View Details
Keywords: Persistence; Project Evaluation; R&D Project Management; Projects; Decision Choices and Conditions; Leadership
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Anton, James J., Alan Jaske, and Dennis Yao. "Leadership and the Value of Persistence." Working Paper, January 2023.
  • April 2014
  • Case

Merrimack Pharmaceuticals, Inc. (A)

By: Amy C. Edmondson, Bethany S. Gerstein and Melissa Valentine
In 2006, Merrimack Pharmaceuticals was a fast-growing biotechnology company. Its leadership team was divided over whether to keep R&D organized in functional departments or transition to interdisciplinary teams. As a small company, Merrimack's R&D organization had... View Details
Keywords: Teamwork; Interdisciplinary Collaboration; R&D; Biotechnology; Complexity; Innovation Management; Organizational Design; Groups and Teams; Collaborative Innovation and Invention; Research and Development; Biotechnology Industry; Pharmaceutical Industry
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Edmondson, Amy C., Bethany S. Gerstein, and Melissa Valentine. "Merrimack Pharmaceuticals, Inc. (A)." Harvard Business School Case 614-063, April 2014.
  • November 2012
  • Case

The Universalization of L'Oréal

By: Rajiv Lal and Carin-Isabel Knoop
In 2010, half of the world's cosmetics sales came from the so-called emerging markets for the first time; L'Oréal opened three new subsidiaries, in Egypt, Pakistan, and Kazakhstan; and the Paris, France-based cosmetics and personal care powerhouse declared its... View Details
Keywords: Retailing; Marketing; Cosmetics Industry; L'Oreal; India; R&D; Globalization; Product Development; Research and Development; Emerging Markets; Retail Industry; Latin America; Asia; Middle East
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Lal, Rajiv, and Carin-Isabel Knoop. "The Universalization of L'Oréal." Harvard Business School Case 513-001, November 2012.
  • September 2013 (Revised November 2015)
  • Case

Living Proof: Are We a Technology Company or a Beauty Company?

By: Willy Shih

Jon Flint came up with the idea of a science-based beauty company while talking with his hairdresser about the problems with typical hair and skin care products. Together with a small team that included Professor Robert Langer of MIT, he committed to assemble a team... View Details

Keywords: Hair Care; Personal Care; Science-based; R&D; Innovation and Invention; Innovation and Management; Innovation Leadership; Innovation Strategy; Technological Innovation; Marketing; Marketing Strategy; Product Marketing; Product Positioning; Science-Based Business; Business Strategy; Commercialization; Corporate Strategy; Technology Platform; Expansion; Beauty and Cosmetics Industry; United States; Boston; Cambridge
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Shih, Willy. "Living Proof: Are We a Technology Company or a Beauty Company?" Harvard Business School Case 614-013, September 2013. (Revised November 2015.)
  • March 2018 (Revised September 2023)
  • Case

X: The Foghorn Decision

By: Robert S. Huckman, Karim R. Lakhani and Kyle R. Myers
In February 2016, Kathy Hannun—a project leader at X, Alphabet Inc.'s so-called "moonshot factory"—had to prepare a recommendation for the senior leadership of X regarding the future of Foghorn, a project she was leading to develop a carbon-neutral process for... View Details
Keywords: Innovation; R&D Project Management; Radical Innovation; Clean Technology; Innovation and Management; Technological Innovation; Energy; Research and Development; Projects; Management; Decision Choices and Conditions; Technology Industry; Energy Industry; Green Technology Industry; California
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Huckman, Robert S., Karim R. Lakhani, and Kyle R. Myers. "X: The Foghorn Decision." Harvard Business School Case 618-060, March 2018. (Revised September 2023.)
  • Summer, 2018
  • Article

Innovation, Reallocation and Growth

By: Daron Acemoglu, Ufuk Akcigit, Harun Alp, Nicholas Bloom and William R. Kerr
We build a model of firm-level innovation, productivity growth, and reallocation featuring endogenous entry and exit. A new and central economic force is the selection between high- and low-type firms, which differ in terms of their innovative capacity. We estimate the... View Details
Keywords: Entry; Growth; Industrial Policy; Innovation; R&D; Reallocation; Selection; Market Entry and Exit; Growth and Development; Innovation and Invention; Research and Development; Performance Productivity
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Acemoglu, Daron, Ufuk Akcigit, Harun Alp, Nicholas Bloom, and William R. Kerr. "Innovation, Reallocation and Growth." American Economic Review 108, no. 11 (November 2018): 3450–3491.
  • November 2016
  • Case

Anthony Starks at InSiL Therapeutics (A)

By: Gary Pisano and Vicki Sato
When Bruce Wayne hired Anthony Starks, he thought he had hit a home run by getting the most brilliant and passionate scientist-leader in the field to be his CSO. But a few months in, Wayne and Starks begin to clash over crucial forward-looking decisions about the... View Details
Keywords: Biotech; Silicon; Managing Innovation; Management Challenges; Managing People; Managing Organization; R&D; R&D Project Management; Platform; Venture Capital; Drug Discovery; management; Biotechnology Industry; California
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Pisano, Gary, and Vicki Sato. "Anthony Starks at InSiL Therapeutics (A)." Harvard Business School Case 617-029, November 2016.
  • February 2015
  • Case

TouchTunes and the Connected Digital Jukebox Platform

By: Alan MacCormack and Noah Fisher
The case describes innovation and new product development at TouchTunes, the leader in the Digital Jukebox market. In March 2013, after releasing its innovative "Virtuo" jukebox developed in collaboration with frog design, TouchTunes was at a crossroads. Having... View Details
Keywords: Innovation; Design; R&D; Outsourcing; Platform Strategy; Digital Media; Digital Platforms; Growth and Development Strategy; Innovation and Invention; Product Development; Music Industry
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MacCormack, Alan, and Noah Fisher. "TouchTunes and the Connected Digital Jukebox Platform." Harvard Business School Case 615-051, February 2015.
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