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- July 2025
- Case
Osteoboost: Go-To-Market Strategy in a Healthcare Startup
Osteoboost focuses on how a health care Medtech startup with a new device for treating osteopenia. The firm decides among alternative go-to-market strategies, including B2B (the firm to healthcare providers), DTC (directly to consumers), or some combination of the two... View Details
- July 2025
- Case
The Future in Sight: LumineticsCore and the First Autonomous AI for Diagnostics
By: Michael Lingzhi Li and Tinglong Dai
After two decades of research, Dr. Michael Abramoff successfully launched LumineticsCore—the first autonomous AI system authorized by the FDA to diagnose diabetic retinopathy without physician oversight. The case traces his journey across algorithm design, clinical... View Details
- 2025
- Working Paper
Expert Patients’ Use of Avoidable Health Care
By: Amitabh Chandra, Pragya Kakani and Simone Matecna
We measure whether expert patients – those trained as physicians and nurses – have fewer emergency department visits and the reasons for these differences. Relative to similar patients physicians and nurses had 19.8% and 5.1% fewer ED visits, principally due to fewer... View Details
Chandra, Amitabh, Pragya Kakani, and Simone Matecna. "Expert Patients’ Use of Avoidable Health Care." NBER Working Paper Series, No. 33573, March 2025.
- February 2025
- Case
K Health: Building an AI Physician Model
By: Iavor I. Bojinov, Karim R. Lakhani, Sarah Sasso and Carin-Isabel Knoop
Allon Bloch, CEO and cofounder of K Health, encountered a number of challenges and opportunities to navigate as the company prepared to launch its AI-driven healthcare platform in the U.S. in 2018. The case examines the potential of artificial intelligence to improve... View Details
Keywords: Health Care and Treatment; AI and Machine Learning; Product Launch; Business Strategy; Technology Industry; Health Industry; United States
Bojinov, Iavor I., Karim R. Lakhani, Sarah Sasso, and Carin-Isabel Knoop. "K Health: Building an AI Physician Model." Harvard Business School Case 625-079, February 2025.
- February 2025
- Article
Sale of Private Equity–Owned Physician Practices and Physician Turnover
By: Victoria Berquist, Lev Klarnet and Leemore Dafny
Private equity (PE) ownership of physician practices is increasing, with owners targeting sales, or exits, in 3 to 7 years. Little is known about the association of exit with physician retention and subsequent employment. Using panel data over the period 2014-2020, we... View Details
Berquist, Victoria, Lev Klarnet, and Leemore Dafny. "Sale of Private Equity–Owned Physician Practices and Physician Turnover." JAMA Health Forum 6, no. 2 (February 2025).
- February 2025
- Article
Variation in Batch Ordering of Imaging Tests in the Emergency Department and the Impact on Care Delivery
By: Jacob C. Jameson, Soroush Saghafian, Robert S. Huckman and Nicole Hodgson
Objectives: To examine heterogeneity in physician batch ordering practices and measure the impact of a physician's tendency to batch order imaging tests on patient outcomes and resource utilization.
Study Setting and Design: In this retrospective study, we used... View Details
Study Setting and Design: In this retrospective study, we used... View Details
Keywords: Health Care; Operations Management; Productivity; Health Care and Treatment; Operations; Outcome or Result; Resource Allocation; Health Industry; United States
Jameson, Jacob C., Soroush Saghafian, Robert S. Huckman, and Nicole Hodgson. "Variation in Batch Ordering of Imaging Tests in the Emergency Department and the Impact on Care Delivery." Health Services Research 60, no. 1 (February 2025).
- 2025
- Working Paper
Sale of Private-Equity Owned Physician Practices and Physician Turnover
By: Leemore S. Dafny, Victoria Berquist and Lev Klarnet
- October 16, 2024
- Article
Physicians Can Help Cut Costs. They Just Need the Right Incentives.
By: Susanna Gallani and Derek A. Haas
Health care organizations have long tried to enlist physicians in their effort to control or reduce costs. One effective means for doing so is to create an incentive system that rewards physicians for their contributions. To design such a system, organizations should... View Details
Gallani, Susanna, and Derek A. Haas. "Physicians Can Help Cut Costs. They Just Need the Right Incentives." Harvard Business Review Digital Articles (October 16, 2024).
- 2024
- Working Paper
Does Private Equity Have Any Business Being in the Health Care Business?
By: Nori Gerardo Lietz and Zirui Song
Private Equity (“PE”) has come under increased scrutiny by the press, academics, and policymakers, as well as the public, for its investments in health care delivery. This scrutiny has been exacerbated by recent high profile hospital bankruptcies following PE... View Details
Lietz, Nori Gerardo, and Zirui Song. "Does Private Equity Have Any Business Being in the Health Care Business?" Harvard Business School Working Paper, No. 25-012, September 2024.
- August 13, 2024
- Editorial
Can AI Save Physicians from Burnout?
By: Susanna Gallani, Lidia Moura and Katie Sonnefeldt
Gallani, Susanna, Lidia Moura, and Katie Sonnefeldt. "Can AI Save Physicians from Burnout?" Harvard Business School Working Knowledge (August 13, 2024).
- August 2024 (Revised July 2025)
- Case
agilon health
By: Regina E. Herzlinger and Nicholas Samonas
agilon health is part of the Module 1 of the Innovating Healthcare course: How to Evaluate Innovative Health Ventures.
agilon health serves two pedagogical purposes:
• it faces a difficult evaluation about how to grow the firm
• It introduces the students to... View Details
Keywords: Health Industry
- July 2024
- Article
Mass General Brigham’s Patient-Reported Outcomes Measurement System: A Decade of Learnings
By: Jason B. Liu, Robert S. Kaplan, David W. Bates, Mario O. Edelen, Rachel C. Sisodia and Andrea L. Pusic
This article describes the strategies that leaders at the Mass General Brigham (MGB) health system have used in launching a standardized patient-reported outcome measure (PROM) collection program in 2012, a major step in the value-based transformation of health care.... View Details
Keywords: Patient-reported Outcomes; Value Based Health Care; Health Care and Treatment; Transformation; Outcome or Result; Organizational Change and Adaptation; Performance Improvement; Health Industry
Liu, Jason B., Robert S. Kaplan, David W. Bates, Mario O. Edelen, Rachel C. Sisodia, and Andrea L. Pusic. "Mass General Brigham’s Patient-Reported Outcomes Measurement System: A Decade of Learnings." NEJM Catalyst Innovations in Care Delivery 5, no. 7 (July 2024).
- June 2024
- Article
Enhancing Value and Well-Being: The Basket of Motivators Framework for Aligning Neurology Clinical Practices with Performance Outcomes
By: Peter N. Hadar, Susanna Gallani and Lidia Moura
Physician burnout, which is prevalent in neurology, has accelerated in recent years. While multifactorial, a major contributing factor to burnout is a payment model that rewards volume over quality, leaving physicians overburdened and unfulfilled. The aim of this... View Details
Keywords: Compensation and Benefits; Personal Development and Career; Well-being; Motivation and Incentives
Hadar, Peter N., Susanna Gallani, and Lidia Moura. "Enhancing Value and Well-Being: The Basket of Motivators Framework for Aligning Neurology Clinical Practices with Performance Outcomes." Neurology: Clinical Practice 14, no. 1 (June 2024).
- June 2024 (Revised August 2024)
- Case
Hospital for Special Surgery: Returning to a New Normal? (A)
By: Robert S. Huckman, Michael Lingzhi Li and Camille Gregory
Early on the morning of April 27, 2020, Justin Oppenheimer stood outside the entrance to the lobby of the Hospital for Special Surgery (HSS) Pavilion Building with mixed emotions. On one hand, Oppenheimer, HSS’ Enterprise Chief Operating Officer and Chief Strategy... View Details
Keywords: Operations Management; Scheduling; Optimization; COVID-19; Health Care and Treatment; Operations; Customer Focus and Relationships; Disruption; Health Industry; United States
Huckman, Robert S., Michael Lingzhi Li, and Camille Gregory. "Hospital for Special Surgery: Returning to a New Normal? (A)." Harvard Business School Case 624-092, June 2024. (Revised August 2024.)
- February 2024
- Article
Representation and Extrapolation: Evidence from Clinical Trials
By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
This article examines the consequences and causes of low enrollment of Black patients in clinical
trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is
more relevant for decision-making by physicians and patients when it... View Details
Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry
Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." Quarterly Journal of Economics 139, no. 1 (February 2024): 575–635.
- January 2024
- Background Note
Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?
By: Regina E. Herzlinger and James Wallace
How can we evaluate if innovative health care ventures can do good—benefit society—and do well—become financially viable? This question is the topic of the first module in the Innovating in Health Care course book.
This note and "Health Stop (A): What Type... View Details
This note and "Health Stop (A): What Type... View Details
- December 4, 2023
- Comment
The Great Resignation, Employment, and Wages in Health Care
By: Amitabh Chandra and Louis-Jonas Heizlsperger
Notwithstanding concerns about staffing levels and burnout in health care, federal wage and employment data does not support the suggestion that a COVID-19 pandemic-related spike in quitting has had an enduring impact for hospitals or physician offices. Employment in... View Details
Chandra, Amitabh, and Louis-Jonas Heizlsperger. "The Great Resignation, Employment, and Wages in Health Care." NEJM Catalyst (December 4, 2023).
- October 2023
- Article
What Does the Inflation Reduction Act Mean for Patients and Physicians?
By: Amitabh Chandra and Benedic Ippolito
The debate around prescription drug measures in the recently passed U.S. Inflation Reduction Act (IRA), which limit some patients’ out-of-pocket costs, has not fully addressed their effect on physicians and patients via their effect on payers. Reducing patients’ costs... View Details
Chandra, Amitabh, and Benedic Ippolito. "What Does the Inflation Reduction Act Mean for Patients and Physicians?" NEJM Catalyst Innovations in Care Delivery 4, no. 10 (October 2023).
- 2023
- Article
Evidence from the First Shared Medical Appointments (SMAs) Randomised Controlled Trial in India: SMAs Increase the Satisfaction, Knowledge, and Medication Compliance of Patients with Glaucoma
By: Nazlı Sönmez, Kavitha Srinivasan, Rengaraj Venkatesh, Ryan W. Buell and Kamalini Ramdas
In Shared Medical Appointments (SMAs), patients with similar conditions meet the physician together and each receives one-on-one attention. SMAs can improve outcomes and physician productivity. Yet privacy concerns have stymied adoption. In physician-deprived nations,... View Details
Sönmez, Nazlı, Kavitha Srinivasan, Rengaraj Venkatesh, Ryan W. Buell, and Kamalini Ramdas. "Evidence from the First Shared Medical Appointments (SMAs) Randomised Controlled Trial in India: SMAs Increase the Satisfaction, Knowledge, and Medication Compliance of Patients with Glaucoma." e0001648. PLoS Global Public Health 3, no. 7 (2023).
- Summer 2023
- Article
Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?
By: Eric Barrette, Leemore S. Dafny and Karen Shen
Even among commercially insured individuals, opioid use disorder is undertreated in the United States: nearly half receive no treatment within six months of a new diagnosis. Using a difference-in-differences specification exploiting the extension of insurance parity... View Details
Keywords: Opioid Treatment; Medication-assisted Treatment; Substance Use Disorder; Private Insurance; Insurance; Health Care and Treatment
Barrette, Eric, Leemore S. Dafny, and Karen Shen. "Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?" American Journal of Health Economics 9, no. 3 (Summer 2023): 297–330.