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    • All HBS Web  (60)
      • Faculty Publications  (16)

      OpioidsRemove Opioids →

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      • August 2024
      • Case

      Pioneering Pain Management: CWC Alliance Combats the Opioid Epidemic

      By: Susanna Gallani, Karen L. Sedatole and Sarah Mehta
      Set in March 2024, this case is about CWC Alliance (CWC), a nonprofit working to prevent opioid addiction in the U.S. Founder Cammie Wolf Rice launched CWC in 2018 after her son, Christopher Wolf, died of a heroin overdose. Wolf’s dependence on opioids stemmed from a... View Details
      Keywords: Health Care and Treatment; Innovation and Invention; Jobs and Positions; Nonprofit Organizations; Expansion; Growth and Development Strategy; Service Delivery; Mission and Purpose; Health Industry; United States; Georgia (state, US); Atlanta
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      Gallani, Susanna, Karen L. Sedatole, and Sarah Mehta. "Pioneering Pain Management: CWC Alliance Combats the Opioid Epidemic." Harvard Business School Case 125-012, August 2024.
      • January 19, 2024
      • Article

      Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder

      By: Robert S. Kaplan and Sarah E. Wakeman
      U.S. overdose deaths currently exceed 100,000 per year. New facilities, known as bridge clinics, are broadening access to high-quality care by offering outpatient substance use disorder (SUD) treatment with few access barriers. But many of the critical services offered... View Details
      Keywords: Health Care and Treatment; Cost; Adoption
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      Kaplan, Robert S., and Sarah E. Wakeman. "Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder." Health Affairs Forefront (January 19, 2024).
      • January 2024
      • Article

      A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder

      By: Sarah E. Wakeman, Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe and Robert S. Kaplan
      The US fee-for-service payment system under-reimburses clinics offering access to comprehensive treatments for opioid use disorder (OUD). The funding shortfall limits a clinic’s ability to expand and improve access, especially for socially marginalized patients with... View Details
      Keywords: Health Care and Treatment; Cost; Equality and Inequality; Health Industry
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      Wakeman, Sarah E., Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe, and Robert S. Kaplan. "A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder." Journal of Behavioral Health Services & Research 51, no. 1 (January 2024): 22–30.
      • Summer 2023
      • Article

      Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?

      By: Eric Barrette, Leemore S. Dafny and Karen Shen
      Even among commercially insured individuals, opioid use disorder is undertreated in the United States: nearly half receive no treatment within six months of a new diagnosis. Using a difference-in-differences specification exploiting the extension of insurance parity... View Details
      Keywords: Opioid Treatment; Medication-assisted Treatment; Substance Use Disorder; Private Insurance; Insurance; Health Care and Treatment
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      Barrette, Eric, Leemore S. Dafny, and Karen Shen. "Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?" American Journal of Health Economics 9, no. 3 (Summer 2023): 297–330.
      • March 2023 (Revised March 2024)
      • Case

      The Purdue Pharma Bankruptcy: Settling the Opioid Crisis

      By: Kristin Mugford, Carin-Isabel Knoop and Susan Pinckney
      How to get to a fair outcome for claimants in the Purdue Pharma bankruptcy given its significant role in the U.S. opioid crisis. View Details
      Keywords: Regulation; Ethics; Fairness; Insolvency and Bankruptcy; Government Legislation; Courts and Trials; Laws and Statutes; Lawsuits and Litigation; Legal Liability; Crime and Corruption; Negotiation Offer; Negotiation Participants; Negotiation Style; Product Design; Product Development; Brands and Branding; Marketing Strategy; Trust; Government and Politics; Law; Negotiation; Operations; Ownership; Marketing; Social Psychology; Health Care and Treatment; Pharmaceutical Industry; United States
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      Mugford, Kristin, Carin-Isabel Knoop, and Susan Pinckney. "The Purdue Pharma Bankruptcy: Settling the Opioid Crisis." Harvard Business School Case 223-060, March 2023. (Revised March 2024.)
      • January 2023
      • Teaching Note

      The Opioid Settlement and Executive Pay at AmerisourceBergen

      By: Suraj Srinivasan and Li-Kuan Ni
      Teaching Note for HBS Case No 122-014. In 2020, AmerisourceBergen Corporation, a Fortune 50 company in the drug distribution industry, agreed to settle thousands of lawsuits filed nationwide against the company for its opioid distribution practices that critics alleged... View Details
      Keywords: Opioids; Shareholder Activism; Investment Activism; Corporate Accountability; Corporate Governance; Governance Compliance; Governance Controls; Executive Compensation; Risk Management; Corporate Social Responsibility and Impact; Business and Shareholder Relations; Business and Stakeholder Relations; Distribution Industry; Health Industry; Pharmaceutical Industry; United States; West Virginia; Tennessee; Ohio; Pennsylvania
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      Srinivasan, Suraj, and Li-Kuan Ni. "The Opioid Settlement and Executive Pay at AmerisourceBergen." Harvard Business School Teaching Note 123-067, January 2023.
      • December 2022
      • Case

      Managing Pain in the Midst of an Opioid Epidemic

      By: Joshua D. Coval, Richard S. Ruback and Christopher Diak
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      Coval, Joshua D., Richard S. Ruback, and Christopher Diak. "Managing Pain in the Midst of an Opioid Epidemic." Harvard Business School Case 223-041, December 2022.
      • 2022
      • Book

      Complicit: How We Enable the Unethical and How to Stop

      By: Max H. Bazerman
      It is easy to condemn obvious wrongdoers such as Elizabeth Holmes, Adam Neumann, Harvey Weinstein, and the Sackler family. But we rarely think about the many people who supported their unethical or criminal behavior. In each case there was a supporting cast of... View Details
      Keywords: Complicity; Enabling; Ethics; Behavior; Personal Characteristics; Society
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      Bazerman, Max H. Complicit: How We Enable the Unethical and How to Stop. Princeton, NJ: Princeton University Press, 2022.
      • November 2021 (Revised May 2022)
      • Case

      West Virginia: Finding the Right Path Forward

      By: Matthew C. Weinzierl, Christine Keung and Reggie Smith
      Once at the center of the American economy, the state of West Virginia had seen decades of decline as its coal industry fell on hard times. With beautiful but challenging topography, a proud but shrinking population, and a new scourge of the opioid epidemic, the... View Details
      Keywords: Population Health; Geographic Location; Economic Slowdown and Stagnation; Problems and Challenges; Social Issues; West Virginia
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      Weinzierl, Matthew C., Christine Keung, and Reggie Smith. "West Virginia: Finding the Right Path Forward." Harvard Business School Case 722-024, November 2021. (Revised May 2022.)
      • October 2021 (Revised October 2022)
      • Case

      The Opioid Settlement and Controversy Over CEO Pay at AmerisourceBergen

      By: Suraj Srinivasan and Li-Kuan Ni
      In 2020, AmerisourceBergen Corporation, a Fortune 50 company in the drug distribution industry, agreed to settle thousands of lawsuits filed nationwide against the company for its opioid distribution practices that critics alleged had contributed to the nationwide... View Details
      Keywords: Opioids; Drug; Investors; Shareholder Activism; Investment Activism; Executive Compensation; Corporate Accountability; Corporate Governance; Governance Compliance; Governance Controls; Risk Management; Corporate Social Responsibility and Impact; Business and Shareholder Relations; Business and Stakeholder Relations; Legal Liability; Distribution Industry; Health Industry; Pharmaceutical Industry; United States; West Virginia; Tennessee; Ohio; Pennsylvania
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      Srinivasan, Suraj, and Li-Kuan Ni. "The Opioid Settlement and Controversy Over CEO Pay at AmerisourceBergen." Harvard Business School Case 122-014, October 2021. (Revised October 2022.)
      • Article

      Treatment Of Opioid Use Disorder Among Commercially Insured U.S. Adults, 2008–17

      By: Karen Shen, Eric Barrette and Leemore S. Dafny
      There is abundant literature on efforts to reduce opioid prescriptions and misuse, but comparatively little on the treatment provided to people with opioid use disorder (OUD). Using claims data representing 12–15 million nonelderly adults covered through commercial... View Details
      Keywords: Opioid Treatment; Medication-assisted Treatment; Substance Use Disorder; Private Insurance; Health Disorders; Health Care and Treatment; Insurance; United States
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      Shen, Karen, Eric Barrette, and Leemore S. Dafny. "Treatment Of Opioid Use Disorder Among Commercially Insured U.S. Adults, 2008–17." Health Affairs 39, no. 6 (June 2020): 993–1001.
      • December 2019
      • Case

      The Business of Pain: Johnson & Johnson and the Promise of Opioids

      By: Erik Snowberg, Trevor Fetter and Amy W. Schulman
      This case is designed to provide an engrossing overview of stakeholder capitalism through a vigorous discussion of the conflicts that can arise when trying to serve multiple stakeholders. In 2007, Johnson & Johnson’s (J&J) subsidiary Janssen has to decide whether or... View Details
      Keywords: Opioids; Addiction; Stakeholder Capitalism; Business and Stakeholder Relations; Product Launch; Decision Making; Ethics; Social Issues; Pharmaceutical Industry
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      Snowberg, Erik, Trevor Fetter, and Amy W. Schulman. "The Business of Pain: Johnson & Johnson and the Promise of Opioids." Harvard Business School Case 720-420, December 2019.
      • December 2019
      • Supplement

      The Business of Pain: Johnson & Johnson and the Promise of Opioids (B)

      By: Erik Snowberg, Trevor Fetter and Amy W. Schulman
      This case is designed to provide an engrossing overview of stakeholder capitalism through a vigorous discussion of the conflicts that can arise when trying to serve multiple stakeholders. In 2007, Johnson & Johnson’s (J&J) subsidiary Janssen has to decide whether or... View Details
      Keywords: Opioids; Addiction; Business and Stakeholder Relations; Product Launch; Ethics; Society; Pharmaceutical Industry
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      Snowberg, Erik, Trevor Fetter, and Amy W. Schulman. "The Business of Pain: Johnson & Johnson and the Promise of Opioids (B)." Harvard Business School Supplement 720-423, December 2019.
      • November 2019
      • Teaching Note

      Hacking Heroin

      By: Mitchell Weiss and Sarah Mehta
      This teaching note pairs with a case that is used in a course on Public Entrepreneurship, for a first module on "ideas." The case is designed to help students work through the question: where do new ideas to stubborn problems come from? And, in particular, the question... View Details
      Keywords: Public Entrepreneurship; Hackathon; Heroin; Opioids; Crowdsourcing; Public Sector; Entrepreneurship; Innovation and Invention; Collaborative Innovation and Invention; Health Pandemics; Public Administration Industry; Health Industry; Ohio; Cincinnati
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      Weiss, Mitchell, and Sarah Mehta. "Hacking Heroin." Harvard Business School Teaching Note 820-063, November 2019.
      • November 2021
      • Article

      Gaussian Process Subset Scanning for Anomalous Pattern Detection in Non-iid Data

      By: William Herlands, Edward McFowland III, Andrew Gordon Wilson and Daniel B. Neill
      Identifying anomalous patterns in real-world data is essential for understanding where, when, and how systems deviate from their expected dynamics. Yet methods that separately consider the anomalousness of each individual data point have low detection power for subtle,... View Details
      Keywords: Pattern Detection; Subset Scanning; Gaussian Processes; Mathematical Methods
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      Herlands, William, Edward McFowland III, Andrew Gordon Wilson, and Daniel B. Neill. "Gaussian Process Subset Scanning for Anomalous Pattern Detection in Non-iid Data." Proceedings of Machine Learning Research (PMLR) 84 (2018): 425–434. (Also presented at the 21st International Conference on Artificial Intelligence and Statistics (AISTATS), 2018.)
      • August 2017
      • Case

      Hacking Heroin

      By: Mitchell Weiss and Sarah Mehta
      "Hacking Heroin" was the first hackathon that Annie Rittgers, founder of Cincinnati-based 17a, had organized or even attended. "There will continue to be a lot of preventable overdose deaths and wasted potential if the opioid crisis continues unabated," she said.... View Details
      Keywords: Public Entrepreneurship; Hackathon; Heroin; Opioids; Crowdsourcing; Public Sector; Entrepreneurship; Innovation and Invention; Collaborative Innovation and Invention; Health Pandemics; Public Administration Industry; Health Industry; Ohio; Cincinnati
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      Weiss, Mitchell, and Sarah Mehta. "Hacking Heroin." Harvard Business School Case 818-010, August 2017.
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