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    • All HBS Web  (89)
      • Faculty Publications  (18)

      Licensing Agreements In BiopharmacyRemove Licensing Agreements In Biopharmacy →

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      • 2025
      • Working Paper

      Transferability MATTRs: Towards Understanding Antecedents of Strategic Licensing

      By: Dafna F. Bearson and Maria P. Roche
      This paper examines the antecedents of firms’ decisions to license intellectual property (IP). We propose a conceptual framework emphasizing two critical factors: (1) transferability, which we define as the ease of moving knowledge embodied in inventions across firm... View Details
      Keywords: Technological Innovation; Innovation Strategy; Intellectual Property; Value Creation
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      Bearson, Dafna F., and Maria P. Roche. "Transferability MATTRs: Towards Understanding Antecedents of Strategic Licensing." Harvard Business School Working Paper, No. 25-042, March 2025.
      • December 2024
      • Case

      Xtalic

      By: Joshua Lev Krieger and Jim Matheson
      This case study examines the commercialization efforts of Xtalic, a startup founded by MIT scientists based on their discovery of a novel material science method to protect metal substrates. The case focuses on the strategic decisions involved in bringing this... View Details
      Keywords: Innovation & Entrepreneurship; Innovation and Management; Entrepreneurial Finance; Entrepreneurship; Business Model; Business Startups; Agreements and Arrangements; Science-Based Business; Commercialization
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      Krieger, Joshua Lev, and Jim Matheson. "Xtalic." Harvard Business School Case 825-103, December 2024.
      • 2024
      • Working Paper

      The Value of Silence: The Effect of UMG’s Licensing Dispute with TikTok on Music Demand

      By: Mengjie (Magie) Cheng, Elie Ofek and Hema Yoganarasimhan
      Social media platforms like TikTok have transformed how music is discovered, consumed, and monetized. This study examines the implications of the dispute between TikTok and Universal Music Group (UMG), which resulted in UMG excluding its music from TikTok from... View Details
      Keywords: Demand And Consumers; Monetization; Social Media; Revenue; Conflict and Resolution; Music Industry
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      Cheng, Mengjie (Magie), Elie Ofek, and Hema Yoganarasimhan. "The Value of Silence: The Effect of UMG’s Licensing Dispute with TikTok on Music Demand." Harvard Business School Working Paper, No. 25-014, July 2024. (Revised October 2024.)
      • June 2020
      • Case

      Jill Draeger

      By: Howard H. Stevenson and Michael J. Roberts
      The Jill Draeger case is designed as an introduction to a general course on entrepreneurship. It is appropriate for many levels of students. It attempts to portray the archetype of opportunity-focused, resource-constrained behavior that is the hallmark of... View Details
      Keywords: Entrepreneurship; Personal Development and Career; Opportunities; Negotiation; Agreements and Arrangements; Risk Management
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      Stevenson, Howard H., and Michael J. Roberts. "Jill Draeger." Harvard Business School Brief Case 920-578, June 2020.
      • April 2020 (Revised June 2020)
      • Case

      Oriental Land Co., Ltd.—Tokyo Disney Resort

      By: Ramon Casadesus-Masanell and Akiko Kanno
      This case describes the history of Oriental Land Co. Ltd.’s (OLC's) Tokyo Disney Resort (TDR), its operations, the extent of vertical integration, and the challenges it faced in 2018 as OLC's chairman and CEO, Toshio Kagami, contemplated how best to deal with... View Details
      Keywords: Strategy For Multi-business Firm; Business Models; Growth; Theme Parks; Disney; Disney Parks; Licensing; Royalties; Two-part Tariffs; Oriental Land Co.; Tokyo Disneyland; Tokyo DisneySea; Tokyo Disney Resort; Tokyo Disney; Growth Strategy; Hotels; Hotel Industry; Partnership; Development; Attractions; Rides; Urayasu; Kagami; Congestion; Pricing; Amusement Parks; Amusement Park Industry; Brand; Branding; History; OLC; Corporate Strategy; Competitive Strategy; Business History; Price; Retention; Growth and Development; Growth and Development Strategy; Brands and Branding; Agreements and Arrangements; Contracts; Operations; Vertical Integration; Problems and Challenges; Partners and Partnerships; Business Strategy; Expansion; Rail Transportation; Transportation Networks; Accommodations Industry; Entertainment and Recreation Industry; Tourism Industry; Asia; Japan; Tokyo; United States
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      Casadesus-Masanell, Ramon, and Akiko Kanno. "Oriental Land Co., Ltd.—Tokyo Disney Resort." Harvard Business School Case 720-460, April 2020. (Revised June 2020.)
      • May 2019
      • Case

      Whiskey and Cheddar: Ingredient Branding at the Caesan Cheese Cooperative (Brief Case)

      By: John A. Quelch and Katherine B. Hartman
      The Caesan Cheese Cooperative is considering introducing a new high-quality, high-margin artisan whiskey cheddar cheese. Deidra Kelly, vice president of marketing and product development at Caesan, must recommend to the Board of Directors whether to launch the product... View Details
      Keywords: Brands and Branding; Product Development; Management; Product Marketing; Product Positioning; Marketing Strategy; Partners and Partnerships; Food and Beverage Industry
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      Quelch, John A., and Katherine B. Hartman. "Whiskey and Cheddar: Ingredient Branding at the Caesan Cheese Cooperative (Brief Case)." Harvard Business School Brief Case 919-521, May 2019.
      • February 2015 (Revised November 2015)
      • Supplement

      Building an Integrated Biopharma Company: Crucell (B)

      By: Richard G. Hamermesh, Marianne Van Der Steen and Susan Harmeling
      The Crucell (B) case updates events at Crucell since 2009. In September, 2009, Johnson & Johnson acquired 18% of Crucell for $400 million. This investment was part of a business development deal. Subsequently, in 2012, Johnson & Johnson acquired Crucell for $2.8... View Details
      Keywords: Biotechnology; Biopharmacy Company; Licensing Agreements In Biopharmacy; Licensing; Human Cell-line Technology; Vaccine; Healthcare Innovation; Global Health; Entrepreneurship; Health Care and Treatment; Acquisition; Innovation and Invention; Biotechnology Industry; Pharmaceutical Industry
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      Hamermesh, Richard G., Marianne Van Der Steen, and Susan Harmeling. "Building an Integrated Biopharma Company: Crucell (B)." Harvard Business School Supplement 815-086, February 2015. (Revised November 2015.)
      • February 2015 (Revised November 2015)
      • Case

      Building an Integrated Biopharma Company: Crucell (A)

      By: Richard G. Hamermesh, Marianne Van Der Steen and Susan S. Harmeling
      By 2009, Crucell had become the largest biopharma company in the Netherlands and a symbol of national pride. The case traces the evolution of the company from a University spin-off into a fully-integrated company. Crucell's success, particularly in the vaccine space,... View Details
      Keywords: Biotechnology; Biopharmacy Company; Licensing; Licensing Agreements In Biopharmacy; Human Cell-line Technology; Vaccine; Healthcare Innovation; Global Health; Partners and Partnerships; Entrepreneurship; Growth and Development Strategy; Biotechnology Industry; Pharmaceutical Industry; Netherlands
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      Hamermesh, Richard G., Marianne Van Der Steen, and Susan S. Harmeling. "Building an Integrated Biopharma Company: Crucell (A)." Harvard Business School Case 815-085, February 2015. (Revised November 2015.)
      • June 2011 (Revised November 2014)
      • Case

      Vehbi Koç and the Making of Turkey's Largest Business Group

      By: Asli M. Colpan and Geoffrey Jones
      The case describes the creation of Turkey's largest business group by Vehbi Koç. The foundation of this group in the interwar years, and its subsequent diversification into many industries, including automobiles, household goods, and services, is analysed. The case... View Details
      Keywords: Emerging Markets; Entrepreneurship; Globalization; Organizational Structure; Diversification; Manufacturing Industry; Turkey
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      Colpan, Asli M., and Geoffrey Jones. "Vehbi Koç and the Making of Turkey's Largest Business Group." Harvard Business School Case 811-081, June 2011. (Revised November 2014.)
      • September 2010 (Revised July 2013)
      • Case

      Alnylam Pharmaceuticals: Building Value from the IP Estate

      By: Willy C. Shih and Sen Chai
      The learning objective of this case is to help students recognize the interplay between intellectual property (IP) rights and corporate strategy. We do this by examining what is a fairly atypical circumstance today in which a single firm is able to secure what it... View Details
      Keywords: Patents; Lawsuits and Litigation; Rights; Competitive Strategy; Corporate Strategy; Biotechnology Industry; Pharmaceutical Industry; United States
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      Shih, Willy C., and Sen Chai. "Alnylam Pharmaceuticals: Building Value from the IP Estate." Harvard Business School Case 611-009, September 2010. (Revised July 2013.)
      • June 2010 (Revised July 2011)
      • Case

      Classic Knitwear and Guardian: A Perfect Fit?

      By: John A. Quelch and Patricia Girardi
      Classic Knitwear manufactures and distributes casual apparel, either unbranded or under a private-label brand name. Partly because Classic has no brand recognition with consumers, gross margins are low. To improve margins, the company considers partnering via a... View Details
      Keywords: Market Research; Forecasting; Consumer Marketing; New Product Marketing; Product Lines; Merchandising; Branding; Demand and Consumers; Partners and Partnerships; Marketing Strategy; Forecasting and Prediction; Product Marketing; Brands and Branding; Product Development; Manufacturing Industry; Apparel and Accessories Industry
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      Quelch, John A., and Patricia Girardi. "Classic Knitwear and Guardian: A Perfect Fit?" Harvard Business School Brief Case 104-217, June 2010. (Revised July 2011.)
      • March 2008 (Revised February 2009)
      • Case

      Transparent Value LLC

      By: Sharon P. Katz, Krishna G. Palepu and Aldo Sesia, Jr.
      Leading index company Dow Jones recently signed a license and joint marketing agreement with Transparent Value LLC, the creator of a new fundamentals-based valuation methodology. The agreement allowed Dow Jones to offer a family of indexes based on the Transparent... View Details
      Keywords: Asset Management; Stocks; Price; Performance Expectations; Mathematical Methods; Valuation
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      Katz, Sharon P., Krishna G. Palepu, and Aldo Sesia, Jr. "Transparent Value LLC." Harvard Business School Case 108-069, March 2008. (Revised February 2009.)
      • September 2007 (Revised May 2009)
      • Case

      Syndexa and Technology Transfer at Harvard University

      By: Richard G. Hamermesh and David Kiron
      Gokhan Hotamisligil is a star researcher at Harvard School of Public Health who has made groundbreaking discoveries linking fat cells, inflammation, and diabetes. He now wants to form a company to commercialize these discoveries. At the same time, Isaac Kohlberg, the... View Details
      Keywords: Business Startups; Higher Education; Entrepreneurship; Innovation and Invention; Intellectual Property; Rights; Agreements and Arrangements; Science-Based Business; Commercialization; Biotechnology Industry; Health Industry
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      Hamermesh, Richard G., and David Kiron. "Syndexa and Technology Transfer at Harvard University." Harvard Business School Case 808-073, September 2007. (Revised May 2009.)
      • January 2007
      • Background Note

      Note on Biotech Business Development

      By: Richard G. Hamermesh and Robert F. Higgins
      Describes the business development process in biotechnology companies. Topics covered include: participants in the licensing process and their interests, the major steps in the licensing process, the terms that are part of most agreements, and the most contentious... View Details
      Keywords: Agreements and Arrangements; Entrepreneurship; Intellectual Property; Biotechnology Industry
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      Hamermesh, Richard G., and Robert F. Higgins. "Note on Biotech Business Development." Harvard Business School Background Note 807-032, January 2007.
      • March 2004 (Revised June 2006)
      • Case

      Journey to Sakhalin: Royal Dutch/Shell in Russia (A)

      By: Rawi E. Abdelal
      Operations of Royal Dutch/Shell in Russia included a strategic alliance with Gazprom, the country's natural gas monopoly, the development of the Salym oil fields in Siberia, and a small retail refilling network in St. Petersburg. Focuses on the Sakhalin II project.... View Details
      Keywords: Decision Making; Energy Generation; Foreign Direct Investment; Lawfulness; Agreements and Arrangements; Alliances; Business and Government Relations; Energy Industry; Russia
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      Abdelal, Rawi E. "Journey to Sakhalin: Royal Dutch/Shell in Russia (A)." Harvard Business School Case 704-040, March 2004. (Revised June 2006.)
      • January 1996
      • Case

      Outrage in Cyberspace: CompuServe and the GIF Patent

      By: Josh Lerner and Benjamin Conway
      CompuServe, an online services vendor, informs its software developers that they must enter into a licensing agreement to use the popular GIF compression. CompuServe claims that it is forced to do so because Unisys is enforcing its patent rights in this area. Others... View Details
      Keywords: Patents; Technological Innovation; Internet and the Web; Information Technology; Competitive Strategy; Internet and the Web; Web Services Industry
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      Lerner, Josh, and Benjamin Conway. "Outrage in Cyberspace: CompuServe and the GIF Patent." Harvard Business School Case 296-057, January 1996.
      • January 1996
      • Case

      Palm Computing, Inc. (A)

      By: Myra M. Hart
      Discusses patents, licenses, and deal making in a start-up venture. The entrepreneur, Jeff Hawkins, holds a patent on Palm Print, a pattern recognition algorithm. After licensing Palm Print to his employer, he led three years of development of commercial products for... View Details
      Keywords: Intellectual Property; Patents; Agreements and Arrangements; Negotiation Deal; Business Startups; Management Teams
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      Hart, Myra M. "Palm Computing, Inc. (A)." Harvard Business School Case 396-245, January 1996.
      • 2018
      • Chapter

      Are Licensing Markets Local? An Analysis of the Geography of Vertical Licensing Agreements in Bio-Pharmaceuticals

      By: Juan Alcacer, John Cantwell and Michelle Gittelman
      As the value chain of the pharmaceutical industry disaggregates, upstream discovery is increasingly carried out by small research-specialized firms while downstream development, testing and marketing is conducted by global pharmaceutical firms. Licensing plays an... View Details
      Keywords: Geographic Location; Local Range; Rights; Research and Development; Biotechnology Industry; Pharmaceutical Industry
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      Alcacer, Juan, John Cantwell, and Michelle Gittelman. "Are Licensing Markets Local? An Analysis of the Geography of Vertical Licensing Agreements in Bio-Pharmaceuticals." In Location of Biopharmaceutical Activity, edited by Iain M. Cockburn and Matthew J. Slaughter. National Bureau of Economic Research, forthcoming.
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