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      • Faculty Publications  (216)

      Health & WellnessRemove Health & Wellness →

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      • February 2025
      • Case

      Abiomed: Clinical Trials and Tribulations

      By: Satish Tadikonda, Faith Robertson and William Marks
      After receiving 510(k) clearance for the Impella 2.5 device, Abiomed had proceeded to conduct a premarket approval (PMA) process as well to prove clinical superiority, earn greater protection, and extend commercial runway. However, in the middle of the clinical trial... View Details
      Keywords: Corporate Disclosure; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Medical Devices and Supplies Industry
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      Tadikonda, Satish, Faith Robertson, and William Marks. "Abiomed: Clinical Trials and Tribulations." Harvard Business School Case 825-096, February 2025.
      • December 5, 2024
      • Article

      A Consensus Definition of Creativity in Surgery: A Delphi Study Protocol

      By: Alex Thabane, Tyler McKechnie, Phillip Staibano, Vikram Arora, Goran Calic, Jason W. Busse, Sameer Parpia and Mohit Bhandari
      Introduction
      Clear definitions are essential in science, particularly in the study of abstract phenomena like creativity. Due to its inherent complexity and domain-specific nature, the study of creativity has been complicated, as evidenced by the various... View Details
      Keywords: Creativity; Health Care and Treatment; Outcome or Result; Measurement and Metrics
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      Thabane, Alex, Tyler McKechnie, Phillip Staibano, Vikram Arora, Goran Calic, Jason W. Busse, Sameer Parpia, and Mohit Bhandari. "A Consensus Definition of Creativity in Surgery: A Delphi Study Protocol." PLoS ONE 19, no. 12 (December 5, 2024).
      • 2024
      • Article

      Psychological Safety as an Enduring Resource amid Constraints

      By: Hassina Bahadurzada, Amy C. Edmondson and Michaela J. Kerrissey
      While psychological safety is recognized as valuable in healthcare, its relationship to resource constraints is not well understood. We investigate whether psychological safety mitigates the negative impact of resource constraints on employees. Leveraging longitudinal... View Details
      Keywords: Burnout; Psychological Safety; Healthcare Administration; Health Care and Treatment; Employees; Retention; Well-being; Health Industry
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      Bahadurzada, Hassina, Amy C. Edmondson, and Michaela J. Kerrissey. "Psychological Safety as an Enduring Resource amid Constraints." Special Issue on Psychological Safety in Healthcare Settings. International Journal of Public Health 69 (2024).
      • November 2024
      • Case

      Demond Martin and WellWithAll

      By: Hise Gibson, Archie L. Jones and Ai-Ling Jamila Malone
      This case study chronicles the transformative entrepreneurial path of Demond Martin, co-founder and CEO of WellWithAll, a health and wellness startup. Motivated by a pivotal life experience and deep concern for racial health inequities, Martin transitions from a... View Details
      Keywords: Customers; Diversity; Ethnicity; Race; Health; Recruitment; Leadership Style; Management Style; Brands and Branding; Marketing Strategy; Product Launch; Product Positioning; Organizational Culture; Mission and Purpose; Relationships; Trust; Business Strategy; Competitive Strategy; Competitive Advantage; Investment; Business Startups; Transition; Entrepreneurship; Health Industry; Health Industry; Health Industry; United States; Chicago; Boston; Atlanta; North Carolina; District of Columbia
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      Gibson, Hise, Archie L. Jones, and Ai-Ling Jamila Malone. "Demond Martin and WellWithAll." Harvard Business School Case 625-041, November 2024.
      • November 2024
      • Background Note

      Social Enterprise in the MENA Region

      By: Brian Trelstad and Ahmed Dahawy
      This research note provides an overview of the socio-economic landscape of social enterprise in the Middle East and North Africa. It highlights the diversity of players in the region including social enterprise organizations (in their many forms) and supporting... View Details
      Keywords: MENA; Non-Governmental Organizations; Nonprofit Organizations; Civil Society or Community; Social Issues; Diasporas; Social Entrepreneurship; Cultural Entrepreneurship; Environmental Sustainability; Geographic Scope; Health Care and Treatment; Philanthropy and Charitable Giving; Business and Community Relations; Business and Government Relations; Social and Collaborative Networks; Demographics; Health Industry; Health Industry; Health Industry; Egypt; Morocco; North Africa; Tunisia; Jordan; Lebanon; Saudi Arabia; United Arab Emirates; Dubai; Middle East
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      Trelstad, Brian, and Ahmed Dahawy. "Social Enterprise in the MENA Region." Harvard Business School Background Note 325-041, November 2024.
      • October 18, 2024
      • Article

      Why Workplace Well-Being Programs Don’t Achieve Better Outcomes

      By: Jazz Croft, Acacia Parks and Ashley Whillans
      By 2026, global corporate spending on wellness programs is set to top $94.6 billion, yet anticipated improvements in well-being are not being realized, and, in fact, mental health needs are continuing to rise around the world. Drawing on a large body of recent... View Details
      Keywords: Organizational Culture; Employees; Well-being
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      Croft, Jazz, Acacia Parks, and Ashley Whillans. "Why Workplace Well-Being Programs Don’t Achieve Better Outcomes." Harvard Business Review Digital Articles (October 18, 2024).
      • October 2024
      • Supplement

      NOW PT (A)

      By: George A Riedel, Allison J. Wigen and Dave Habeeb
      Pre-Abstract: Instructors should consider the timing of making videos available to students, as they may reveal key case details.

      Abstract: In fall 2021, a team of students from the HBS Impact Investing Fund considered Neurologic Optimal Wellness Physical... View Details
      Keywords: Health Care and Treatment; Medical Specialties; Investment; Business Model; Health Industry; United States
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      Riedel, George A., Allison J. Wigen, and Dave Habeeb. "NOW PT (A)." Harvard Business School Multimedia/Video Supplement 325-701, October 2024.
      • October 2024
      • Supplement

      NOW PT (B)

      By: George A Riedel, Allison J. Wigen and Dave Habeeb
      Pre-Abstract: Instructors should consider the timing of making videos available to students, as they may reveal key case details.

      Abstract: In fall 2021, a team of students from the HBS Impact Investing Fund considered Neurologic Optimal Wellness Physical... View Details
      Keywords: Health Care and Treatment; Medical Specialties; Business Model; Investment; Health Industry; United States
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      Riedel, George A., Allison J. Wigen, and Dave Habeeb. "NOW PT (B)." Harvard Business School Multimedia/Video Supplement 325-702, October 2024.
      • October 2024
      • Case

      Southern California Industrial: Freezer Drive

      By: Arthur I. Segel, W. Matt Kelly and Dwight Angelini
      In the midst of the COVID-19 pandemic, a Boston based real estate private equity firm was seeking to make their very first West Coast investments in hopes of establishing their presence in the strategic region. An exciting property suddenly became available on the... View Details
      Keywords: Real Estate Development; Acquisition; Health Pandemics; Risk and Uncertainty; Expansion; Cost vs Benefits; Investment Return; Real Estate Industry
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      Segel, Arthur I., W. Matt Kelly, and Dwight Angelini. "Southern California Industrial: Freezer Drive." Harvard Business School Case 225-015, October 2024.
      • September 2024
      • Case

      Myeloma Investment Fund

      By: Kyle Myers and Scott Sawaya
      This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.

      The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details
      Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation & Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry
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      Myers, Kyle, and Scott Sawaya. "Myeloma Investment Fund." Harvard Business School Case 625-047, September 2024.
      • 2024
      • Working Paper

      Does Private Equity Have Any Business Being in the Health Care Business?

      By: Nori Gerardo Lietz and Zirui Song
      Private Equity (“PE”) has come under increased scrutiny by the press, academics, and policymakers, as well as the public, for its investments in health care delivery. This scrutiny has been exacerbated by recent high profile hospital bankruptcies following PE... View Details
      Keywords: Private Equity; Government Administration; Acquisition; Health Industry
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      Lietz, Nori Gerardo, and Zirui Song. "Does Private Equity Have Any Business Being in the Health Care Business?" Harvard Business School Working Paper, No. 25-012, September 2024.
      • August 2024
      • Case

      Pioneering Pain Management: CWC Alliance Combats the Opioid Epidemic

      By: Susanna Gallani, Karen L. Sedatole and Sarah Mehta
      Set in March 2024, this case is about CWC Alliance (CWC), a nonprofit working to prevent opioid addiction in the U.S. Founder Cammie Wolf Rice launched CWC in 2018 after her son, Christopher Wolf, died of a heroin overdose. Wolf’s dependence on opioids stemmed from a... View Details
      Keywords: Health Care and Treatment; Innovation and Invention; Jobs and Positions; Nonprofit Organizations; Expansion; Growth and Development Strategy; Service Delivery; Mission and Purpose; Health Industry; United States; Georgia (state, US); Atlanta
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      Gallani, Susanna, Karen L. Sedatole, and Sarah Mehta. "Pioneering Pain Management: CWC Alliance Combats the Opioid Epidemic." Harvard Business School Case 125-012, August 2024.
      • June 2024 (Revised December 2024)
      • Case

      Lana Ghanem: Pushing the Boundaries of Health Care Through Venture Capital

      By: Joshua D. Margolis and Ahmed Dahawy
      Lana Ghanem, managing director of Hikma Ventures, the corporate venture arm of larger pharmaceutical group Hikma, is considering how to grow the venture arm as well as progress her own career. Over the past few years Hikma's executive team had been pressuring the... View Details
      Keywords: Business Divisions; Corporate Entrepreneurship; Investment; Corporate Governance; Health Care and Treatment; Leadership Development; Business or Company Management; Growth and Development Strategy; Business Strategy; Venture Capital; Personal Development and Career; Health Industry; Health Industry; Jordan
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      Margolis, Joshua D., and Ahmed Dahawy. "Lana Ghanem: Pushing the Boundaries of Health Care Through Venture Capital." Harvard Business School Case 424-075, June 2024. (Revised December 2024.)
      • May 2024
      • Case

      SofMedica Group: Managing Growth

      By: Boris Groysberg and Sarah L. Abbott
      SofMedica Group had expanded from its origins as a medical equipment distributor in Romania to a holding company with four business lines operating in six countries. This expansion had been driven by SofMedica’s mission: to make cutting edge medical technology... View Details
      Keywords: Growth; Healthcare Access; Healthcare; Medical Devices; Medical Equipment & Devices; Medical Care; Eastern Europe; Quality Management System; Health Care and Treatment; Growth Management; Education; Organizational Change and Adaptation; Quality; Leadership; Mission and Purpose; Expansion; Developing Countries and Economies; Technological Innovation; Health Industry; Health Industry; Europe; Romania
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      Groysberg, Boris, and Sarah L. Abbott. "SofMedica Group: Managing Growth." Harvard Business School Case 424-027, May 2024.
      • May 2024
      • Article

      The Health Risks of Generative AI-Based Wellness Apps

      By: Julian De Freitas and G. Cohen
      Artifcial intelligence (AI)-enabled chatbots are increasingly being used to help people manage their mental health. Chatbots for mental health and particularly ‘wellness’ applications currently exist in a regulatory ‘gray area’. Indeed, most generative AI-powered... View Details
      Keywords: AI and Machine Learning; Well-being; Governing Rules, Regulations, and Reforms; Applications and Software
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      De Freitas, Julian, and G. Cohen. "The Health Risks of Generative AI-Based Wellness Apps." Nature Medicine 30, no. 5 (May 2024): 1269–1275.
      • April 2024
      • Article

      A Machine Learning Algorithm Predicting Risk of Dilating VUR among Infants with Hydronephrosis Using UTD Classification

      By: Hsin-Hsiao Scott Wang, Michael Lingzhi Li, Dylan Cahill, John Panagides, Tanya Logvinenko, Jeanne Chow and Caleb Nelson
      Backgrounds: Urinary Tract Dilation (UTD) classification has been designed to be a more objective grading system to evaluate antenatal and post-natal UTD. Due to unclear association between UTD classifications to specific anomalies such as vesico-ureteral reflux (VUR),... View Details
      Keywords: Health Disorders; Health Testing and Trials; AI and Machine Learning; Health Industry
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      Wang, Hsin-Hsiao Scott, Michael Lingzhi Li, Dylan Cahill, John Panagides, Tanya Logvinenko, Jeanne Chow, and Caleb Nelson. "A Machine Learning Algorithm Predicting Risk of Dilating VUR among Infants with Hydronephrosis Using UTD Classification." Journal of Pediatric Urology 20, no. 2 (April 2024): 271–278.
      • February 2024
      • Article

      An Economic Framework for Vaccine Prioritization

      By: Mohammad Akbarpour, Eric Budish, Piotr Dworczak and Scott Duke Kominers
      We propose an economic framework for determining the optimal allocation of a scarce supply of vaccines that become gradually available during a public health crisis, such as the Covid-19 pandemic. Agents differ in observable and unobservable characteristics, and the... View Details
      Keywords: Vaccine; Fairness; Public Finance; Public Goods; Allocation Problems; Allocative Efficiency; Allocation Rules; Social Welfare; Pandemics; Inequality; COVID-19; COVID-19 Pandemic; Public Sector; Resource Allocation; Market Design; Marketplace Matching; Public Administration Industry
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      Akbarpour, Mohammad, Eric Budish, Piotr Dworczak, and Scott Duke Kominers. "An Economic Framework for Vaccine Prioritization." Quarterly Journal of Economics 139, no. 1 (February 2024): 359–417. (Authors' names are in certified random order.)
      • January 2024 (Revised October 2024)
      • Case

      DO & CO: Crafting Luxury in the Fast Lane (A)

      By: Juan Alcácer, Esel Cekin, Michael Lee and Noah Roberson
      In July 2023, Attila Dogudan, the chairman of DO & CO, a renowned international catering firm, found himself in a deep conversation with his two sons about a potential new venture: catering for the Las Vegas Grand Prix, a significant step beyond their 31-year history... View Details
      Keywords: Decision Choices and Conditions; Health Pandemics; Opportunities; Corporate Strategy; Luxury; Food and Beverage Industry; Las Vegas
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      Alcácer, Juan, Esel Cekin, Michael Lee, and Noah Roberson. "DO & CO: Crafting Luxury in the Fast Lane (A)." Harvard Business School Case 724-416, January 2024. (Revised October 2024.)
      • January 2024
      • Background Note

      Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?

      By: Regina E. Herzlinger and James Wallace
      How can we evaluate if innovative health care ventures can do good—benefit society—and do well—become financially viable? This question is the topic of the first module in the Innovating in Health Care course book.

      This note and "Health Stop (A): What Type... View Details
      Keywords: Business Model; Health Care and Treatment; Collaborative Innovation and Invention; Mission and Purpose; Alignment; Health Industry
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      Herzlinger, Regina E., and James Wallace. "Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?" Harvard Business School Background Note 324-037, January 2024.
      • 2023
      • Article

      Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset

      By: Junling Liu, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu and Michael Lingzhi Li
      Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address this gap, we introduce CMExam,... View Details
      Keywords: Large Language Model; AI and Machine Learning; Analytics and Data Science; Health Industry
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      Liu, Junling, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu, and Michael Lingzhi Li. "Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset." Conference on Neural Information Processing Systems (NeurIPS), Datasets and Benchmarks Track 36 (2023).
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