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    • All HBS Web  (197)
      • Faculty Publications  (9)

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      • August 2023
      • Case

      Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company

      By: Satish Tadikonda and Brad Prosek
      Constellation Pharmaceuticals was a company focused on epigenetic therapies for cancer patients. Despite a promising start and an early deal with a leading biopharma company, the company weathered twin setbacks in the end of a major research collaboration and the... View Details
      Keywords: Mergers and Acquisitions; Health Care and Treatment; Organizational Change and Adaptation; Research and Development; Business Strategy; Partners and Partnerships; Goals and Objectives; Pharmaceutical Industry; United States
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      Tadikonda, Satish, and Brad Prosek. "Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company." Harvard Business School Case 824-032, August 2023.
      • May 2023 (Revised June 2023)
      • Case

      Novartis (A): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Care and Treatment; Business Model; Leadership; Pharmaceutical Industry; Switzerland
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (A): Reimagining Medicine." Harvard Business School Case 723-443, May 2023. (Revised June 2023.)
      • May 2023 (Revised June 2023)
      • Supplement

      Novartis (B): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Care and Treatment; Business Model; Production; Business Strategy; Pharmaceutical Industry
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (B): Reimagining Medicine." Harvard Business School Supplement 723-444, May 2023. (Revised June 2023.)
      • May 2023 (Revised June 2023)
      • Supplement

      Novartis (C): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Testing and Trials; Health Care and Treatment; Business Model; Problems and Challenges; Pharmaceutical Industry; Switzerland
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (C): Reimagining Medicine." Harvard Business School Supplement 723-445, May 2023. (Revised June 2023.)
      • November 2019 (Revised December 2019)
      • Case

      Martini Klinik: Prostate Cancer Care 2019

      By: Michael E. Porter, Jens Deerberg-Wittram and Thomas W. Feeley
      Since its establishment in 2005, Hamburg’s Martini Klinik had single mindedly focused on prostate cancer care with a commitment to measure long-term health outcomes for every patient. A wholly owned subsidiary of the University Hospital Hamburg, Martini Klinik was a... View Details
      Keywords: Health Care; Michael Porter; Jens Deerberg-Wittram; Clifford Marks; Prostate Cancer; Health Care Policy; Value Agenda; Integrated Practice Units; Outcomes Measurement; Health Care and Treatment; Value; Health Disorders; Insurance; Medical Specialties; Outcome or Result; Measurement and Metrics; Business Processes; Insurance Industry; Health Industry; Germany
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      Porter, Michael E., Jens Deerberg-Wittram, and Thomas W. Feeley. "Martini Klinik: Prostate Cancer Care 2019." Harvard Business School Case 720-359, November 2019. (Revised December 2019.)
      • August 2014 (Revised February 2021)
      • Case

      Hospital for Special Surgery (A)

      By: Regina E. Herzlinger and Stacy Schwartz
      Hospital for Special Surgery, a focused factory for orthopedics and joint disease, is contemplating various growth options: further growth in the United Kingdom's National Health Services, management of hospitals in the United States, and/or hospital consulting.... View Details
      Keywords: Health Care and Treatment; Nonprofit Organizations; Growth and Development Strategy; Cross-Cultural and Cross-Border Issues; Expansion; Health Industry; United Kingdom; United States
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      Herzlinger, Regina E., and Stacy Schwartz. "Hospital for Special Surgery (A)." Harvard Business School Case 315-012, August 2014. (Revised February 2021.)
      • September 2012
      • Supplement

      Intraoperative Radiotherapy for Breast Cancer (B)

      By: Willy Shih
      The intraoperative radiotherapy (IORT) business at Carl Zeiss Meditec had struggled with growth since the time of the (A) case. Though the unit had grown revenues in excess of 50% and had exceeded its EBIT target, it faced several key strategic choices. Should it... View Details
      Keywords: Radiotherapy; Breast Cancer; Brachytherapy; Therapeutic Radiation; Oncology; Oncology Treatment Systems; Elekta AB; Varian Medical Systems; Xoft; Electronic Brachytherapy; Intraoperative Radiotherapy; Disruptive Innovation; Health Care and Treatment; Entrepreneurship; Technological Innovation; Growth and Development Strategy; Health Industry; Germany
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      Shih, Willy. "Intraoperative Radiotherapy for Breast Cancer (B)." Harvard Business School Supplement 613-040, September 2012.
      • August 2012 (Revised February 2021)
      • Case

      Hub and Spoke, HealthCare Global and Additional Focused Factory Models for Cancer Care

      By: Regina E. Herzlinger, Amit Ghorawat, Meera Krishnan and Naiyya Saggi
      This case compares and contrasts four different models for delivering cancer care in India and the US. Students are asked to select the best model in its alignment with the Six Forces in those two countries and Africa, to which one of the models is considering... View Details
      Keywords: Cancer Care Services; Focused Factories For Cancer Care; Hub And Spoke Cancer Care; Cancer Care In The U.S.; Cancer Care In Africa; Cancer Care In India; Health Care and Treatment; Business Model; Six Sigma; Health Disorders; Health Industry; United States; India; Africa
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      Herzlinger, Regina E., Amit Ghorawat, Meera Krishnan, and Naiyya Saggi. "Hub and Spoke, HealthCare Global and Additional Focused Factory Models for Cancer Care." Harvard Business School Case 313-030, August 2012. (Revised February 2021.)
      • August 2012 (Revised August 2014)
      • Case

      Cancer Treatment Centers of America® (A)

      By: Regina E. Herzlinger and Natalie Kindred
      Cancer Treatment Centers of America (CTCA), a U.S. network of four privately owned oncology focused factory hospitals, was weighing options for growth. CTCA was entirely cancer focused and specialized in treating patients with complex and advanced-stage cancers, who... View Details
      Keywords: Cancer; Cancer Treatment; Health Care; Healthcare; Accountability; Outcomes; Outcomes Measurement; Outcomes Reporting; Hub And Spoke Cancer Care; Hub And Spoke; Hub-and-spoke; Focused Factory; Mission and Purpose; Private Ownership; For-Profit Firms; Health Disorders; Medical Specialties; Policy; Business Model; Expansion; Decision Choices and Conditions; Advertising; Health Care and Treatment; Innovation and Invention; Health Industry; United States
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      Herzlinger, Regina E., and Natalie Kindred. "Cancer Treatment Centers of America® (A)." Harvard Business School Case 313-012, August 2012. (Revised August 2014.)
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