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October 2007 (Revised March 2009)
Case

Engineering a Renaissance: The Launch of the Harvard School of Engineering and Applied Sciences

Dean Venky of the newly launched School of Engineering and Applied Sciences is faced with a range of opportunities and challenges as he presides over the launching of a new school of engineering at Harvard University. His opportunities include an ample endowment, a... View Details

Keywords: Higher Education; Engineering; Leading Change; Product Launch; Service Operations; Organizational Change and Adaptation; Alliances; Competitive Strategy

August 2007
Article

Academic Science and Entrepreneurship: Dual Engines of Growth?

By: Josh Lerner, Adam Jaffe, Scott Stern and Marie Thursby

April 2024 (Revised August 2024)
Case

The Engine

By: Joshua Lev Krieger, Jim Matheson, Fiona Murray and Nicholas Christman

The Engine, a venture capital firm founded by MIT to fill a gap in the technology funding landscape by commercializing breakthrough science and technology. Led by managing partner and CEO Katie Rae, the Engine's unique approach involved an unusually longer fund life,... View Details

Keywords: Growth and Development Strategy; Mission and Purpose; Venture Capital; Business Startups; Entrepreneurial Finance; Financial Services Industry

Other Article

Why I Volunteer at the Intel International Science and Engineering Fair

By: Scott Duke Kominers

October 2013 (Revised November 2016)
Case

Carbon Engineering

By: Joseph B. Lassiter III and Sid Misra

Dr. David Keith, President of Carbon Engineering, a company based in Calgary, Alberta, is commercializing a technology to capture carbon dioxide (CO2) from the atmosphere. The company plans to market the captured CO2 to produce low carbon transportation fuels in... View Details

2016
Working Paper

Innovating in Science and Engineering or 'Cashing In' on Wall Street? Evidence on Elite STEM Talent

By: Pian Shu

Using data on MIT bachelor's graduates from 1994 to 2012, this paper empirically examines the extent to which the inflow of elite talent into the financial industry affects the supply of innovators in science and engineering (S&E). I first show that finance does not... View Details

Keywords: Higher Education; Engineering; Personal Development and Career; Science; Finance

September 2019 (Revised August 2020)
Case

Engineering an Inclusive Bioeconomy

By: Tarun Khanna, Raffaella Sadun and Susie L. Ma

In 2019, entrepreneur Juan Carlos Castilla-Rubio was developing a project he hoped could generate and share wealth from the natural resources of the Amazon without destroying those resources. His idea, called Earth Bank of Codes (EBC), would create a library of the... View Details

2008
Working Paper

The Sciences of Design: Observations on an Emerging Field

By: Sandeep Purao, Carliss Y. Baldwin, Alan Hevner, Veda C. Storey, Jan Pries-Heje, Brian Smith and Ying Zhu

The boundaries and contours of design sciences continue to undergo definition and refinement. In many ways, the sciences of design defy disciplinary characterization. They demand multiple epistemologies, theoretical orientations (e.g. construction, analysis or... View Details

Keywords: Design; Engineering; Knowledge Use and Leverage; Research; Science; Boundaries; Value

Article

The Sciences of Design: Observations on an Emerging Field

By: S. Purao, C. Y. Baldwin, A. Hevner, V. Storey, J. Pries-Heje and B. Smith

he boundaries and contours of design sciences continue to undergo definition and refinement. In many ways, the sciences of design defy disciplinary characterization. They demand multiple epistemologies, theoretical orientations (e.g. construction, analysis or... View Details

Keywords: Design; Engineering; Knowledge Use and Leverage; Research; Science; Boundaries; Value

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08 Jul 2024
Research & Ideas

The Critical Computer Science Principles Every Strategic Leader Needs to Know

In an AI-world, leaders who speak technology’s language gain an edge. But that doesn’t mean every manager needs a computer science degree. A handle on a handful of basics goes a long way toward preparing strategic leaders for today’s... View Details

Keywords: by Ben Rand; Technology; Information Technology

2018
Article

Insight into Gender Differences in STEM: Evidence from Peer Reviews in an Engineering Class

By: Jacqueline N. Lane, Bruce Ankenman and Seyed Iravani

As the service industry moves toward self-service, peer feedback serves a critical role in this shift for educational services. Peer feedback is a process by which students provide feedback to each other. One of its major benefits is that it enables students to become... View Details

Keywords: Peer Review; Peer Feedback; STEM Education; Anonymity; Education; Gender; Education Industry

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February 2024 (Revised March 2025)
Case

Moving Science: The Rowland Institute at Harvard

By: Maria P. Roche

Set in 2022, this case describes the considerations involved in organizing the physical relocation of the Rowland Institute at Harvard (RIH), a research institute established in 1980 by Edwin H. Land, the founder of the Polaroid Corporation, for the advancement of... View Details

Keywords: Optics; Engineering; Higher Education; Strategy; Science; Buildings and Facilities; Research and Development; Real Estate Industry; Biotechnology Industry

June 2023
Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai

Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details

Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry

March 2025 (Revised April 2025)
Teaching Note

Moving Science: The Rowland Institute at Harvard

By: Maria Roche

Teaching Note for HBS Case No. 724-441. View Details

Keywords: Optics; Engineering; Higher Education; Strategy; Science; Buildings and Facilities; Research and Development; Real Estate Industry; Biotechnology Industry

May 2009 (Revised August 2013)
Case

The DiagnoFirst Opportunity

By: Robert C. Pozen and Rukmini Balu

John Mason, a principle at Oldwell Partners, was facing a decision of whether or not to invest in DiagnoFirst, a molecular diagnostics firm. DiagnoFirst's key product was a genetic test that identified a subset of prostate cancer patients with a high risk of clinical... View Details

Keywords: Genetic Engineering; Genetically Modified; Genomics; Venture Capital; Patents; Genetics; Decision Choices and Conditions; Laws and Statutes; Investment; Science-Based Business; Biotechnology Industry

December 2016
Case

SEAS in 2016

By: Thomas R. Eisenmann and Kerry Herman

The case explores opportunities and challenges facing the Harvard School of Engineering and Applied Sciences as it 1) grapples with rapid undergraduate enrollment growth and its smaller scale relative to other top engineering schools and 2) prepares to move two-thirds... View Details

Keywords: Business Education; Engineering; Strategy; Partners and Partnerships; Change Management; Education Industry; United States

July 2013
Case

Novozymes: Establishing the Cellulosic Ethanol Value Chain

By: Willy Shih and Sen Chai

As the world's largest producer of industrial enzymes, Novozymes had invested heavily for many years to bio-engineer enzymes that could break down cellulose into fermentable sugar. In 2010, the company had launched what it thought would become a breakthrough product... View Details

January 2017
Case

Danaher Corporation, 2007–2017

By: John R. Wells and Gabriel Ellsworth

On July 2, 2016, Danaher Corporation completed the spinoff of Fortive Corporation. The previous day, Danaher’s stock price had reached an all-time high. In 2015, Danaher had decided to split off its test and measurement, fuel and fleet management, and automation... View Details

Keywords: Danaher; Fortive; Larry Culp; Beckman Coulter; Pall; Life Sciences; Diagnostics; Environmental Operations; Water Management; Dental; Testing; Measurement; Fuel; Fleet Management; Automation; Toolmaking; Tools; Disease Management; Continuous Improvement; Toyota Production System; Divestiture; Spinoffs; Spin-off; Networks; Acquisition; Mergers and Acquisitions; Business Conglomerates; Business Divisions; Business Subsidiaries; Business Units; Business Growth and Maturation; Business Model; For-Profit Firms; Joint Ventures; Restructuring; Engineering; Chemicals; Construction; Machinery and Machining; Profit; Revenue; Globalized Firms and Management; Multinational Firms and Management; Health; Health Care and Treatment; Health Disorders; Medical Specialties; Business History; Job Cuts and Outsourcing; Business or Company Management; Growth and Development Strategy; Management Analysis, Tools, and Techniques; Management Practices and Processes; Management Succession; Management Systems; Resource Allocation; Market Entry and Exit; Measurement and Metrics; Logistics; Business Processes; Organizational Change and Adaptation; Public Ownership; Problems and Challenges; Science; Genetics; Natural Environment; Wastes and Waste Processing; Science-Based Business; Opportunities; Strategy; Adaptation; Business Strategy; Competition; Competitive Strategy; Competitive Advantage; Consolidation; Corporate Strategy; Diversification; Expansion; Technology; Software; Technology Networks; Technology Platform; Value; Valuation; Aerospace Industry; Auto Industry; Biotechnology Industry; Chemical Industry; Computer Industry; Construction Industry; Consumer Products Industry; Distribution Industry; Electronics Industry; Food and Beverage Industry; Health Industry; Industrial Products Industry; Information Technology Industry; Manufacturing Industry; Medical Devices and Supplies Industry; Pharmaceutical Industry; Retail Industry; Rubber Industry; Semiconductor Industry; Shipping Industry; Technology Industry; Telecommunications Industry; Utilities Industry; United States; District of Columbia

12 Sep 2007
Working Paper Summaries

The Ethnic Composition of U.S. Inventors

Keywords: by William R. Kerr

March 2017
Case

SEAS and HBS in Allston

By: Thomas R. Eisenmann and Kerry Herman

The case describes opportunities for and barriers to collaboration between the Harvard School of Engineering and Applied Sciences (SEAS) and Harvard Business School as SEAS prepares to move two-thirds of its faculty and classes to a new campus in Allston, 1.5 miles... View Details

Keywords: Business Education; Engineering; Strategy; Partners and Partnerships; Change Management; Education Industry; United States

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