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July 2025
Case

Toilets for the Underserved: The SURT Commercialization Challenge

By: Maria P. Roche, Anne Marie Knott and Alexander Oettl

In 2021, a breakthrough in sanitation technology developed under the Gates Foundation’s “Reinvent the Toilet” initiative stood ready for commercialization. The Single User Reinvented Toilet (SURT), engineered by Dr. Shannon Yee, offered an off-grid, self-contained... View Details

Keywords: Technological Innovation; Commercialization; Social Issues; Social Enterprise; Public Sector; Private Sector; Market Entry and Exit; Strategic Planning; Engineering; Infrastructure; Innovation Strategy; Utilities Industry; Consumer Products Industry; United States; South Africa; India; France

July 2025
Case

AeroVironment: The MacCready Works Dilemma

By: Willy Shih and Sophie Zimmerman

Scott Newbern, the head of the MacCready Works at AeroVironment (AV) faced a dilemma. The new Strix next-generation drone had just completed a very successful test. AV had launched MacCready Works to focus on transformational innovations that served new markets and new... View Details

Keywords: Organizational Dynamics; Innovation; Innovation Adoption; Organization Alignment; Organization Design; Organization Boundaries; Disruptive Innovation; Disruptive Innovations; Disruptive Technologies; Aerospace Industry; United States

July 2025
Case

Insilico’s Rentosertib Dilemma: A Star in the Pipeline?

By: Michael Lingzhi Li, Brian Mao Fu and Billy Chan

In 2024, the AI biotech firm Insilico Medicine faced a pivotal decision about its new drug, Rentosertib. Discovered and designed using artificial intelligence to treat a lung disease, Rentosertib had successfully advanced to Phase II trials — a first in global... View Details

Keywords: Drug Development; Pharmaceuticals; Artificial Intelligence; Hong Kong; Boston; New York (city, NY)

July 2025
Case

Osteoboost: Go-To-Market Strategy in a Healthcare Startup

By: Regina E. Herzlinger, Ben Creo, Jacob M. Cook and Rachel Lev-Corn

Osteoboost focuses on how a health care Medtech startup with a new device for treating osteopenia. The firm decides among alternative go-to-market strategies, including B2B (the firm to healthcare providers), DTC (directly to consumers), or some combination of the two... View Details

Keywords: Business Startups; Innovation Strategy; Financial Strategy; Health Industry; Medical Devices and Supplies Industry; United States

July 2025
Case

ICARE: Frontline Leadership at Michelin

By: Hubert Joly and Emilie Billaud

In 2025, Michelin CEO Florent Menegaux reflected on the company’s transformation since taking the helm in 2019. Amid a volatile global landscape marked by inflation, rising competition, and geopolitical and sustainability pressures, Michelin had achieved strong... View Details

July 2025
Case

The Future in Sight: LumineticsCore and the First Autonomous AI for Diagnostics

By: Michael Lingzhi Li and Tinglong Dai

After two decades of research, Dr. Michael Abramoff successfully launched LumineticsCore—the first autonomous AI system authorized by the FDA to diagnose diabetic retinopathy without physician oversight. The case traces his journey across algorithm design, clinical... View Details

Keywords: Healthcare; AI; Regulation; Medical Technology; Health Care and Treatment; AI and Machine Learning; Medical Specialties; Health Industry; Technology Industry; United States

June 2025
Case

Transforming a Titan (A)

By: George Serafeim and Lena Duchene

Dimitri Papalexopoulos, fourth-generation CEO of TITAN Cement, must decide whether to keep leading the 120-year-old, family-controlled firm or hand the reins to new management. Over 26 years he has turned TITAN from a domestic player into an internationally diversified... View Details

June 2025
Supplement

Transforming a Titan (B)

By: George Serafeim and Lena Duchene

After a global search the board appoints Marcel Cobuz—ex-LafargeHolcim executive with deep innovation experience—as TITAN’s first non-family CEO. Cobuz co-creates a four-pillar roadmap: sharpen the core cement portfolio, accelerate low-carbon products and aggregates,... View Details

Keywords: CEO Succession; CEO Role; Family Business; AI and Machine Learning; Green Technology; Multinational Firms and Management; Selection and Staffing; Collaborative Innovation and Invention; Leadership; Strategic Planning; Business Strategy

June 2025
Case

Scale AI Scales Up

By: Boris Groysberg and Sarah L. Abbott

Scale AI, the data labeling and AI infrastructure company, had grown rapidly since it was founded in 2016; however, as Scale’s generative AI business was taking off, Alexandr Wang, Scale’s founder and CEO, became concerned that Scale was slowing down. Wang and the... View Details

Keywords: Technology And Innovation Management; Entrepreneur; Managing Growth; Hiring; Generative Ai; Data Labeling; Scale; AI and Machine Learning; Entrepreneurship; Talent and Talent Management; Growth Management; Leadership; Organizational Culture; Business Startups; Selection and Staffing; Technology Industry; United States

2025
Working Paper

Small Business Innovation Applied to National Needs

By: Kyle Myers, Lauren Lanahan and Evan E. Johnson

Small businesses have long supplied a disproportionate share of major innovations in the United States. We review a centerpiece policy on this topic: the U.S. Small Business Innovation Research (SBIR) program. We trace its legislative history and summarize program... View Details

Keywords: Small Business; Innovation and Invention; Government Legislation; Entrepreneurial Finance; Business and Government Relations

May 2025
Case

Dell Med: Transforming Care Delivery & Payment

By: Robert S. Kaplan, David N. Bernstein and Mary L. Witkowski

Health care in the U.S. and globally continues to undergo massive transformation, surging towards a system that rewards value for patients. However, widespread adoption of value-based health care remains a challenge. This case study focuses on the care delivery... View Details

Keywords: Integrated Practice Units; Outcomes Measurement; Time-Driven Activity-Based Costing; Health Care and Treatment; Business Strategy; Leading Change; Decisions; Transformation; Service Delivery; Adoption; Value; Health Industry; United States; Texas

May 2025 (Revised June 2025)
Supplement

Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (D)

By: Linda A. Hill and Lydia Begag

This fourth installment in the Pfizer Global Clinical Supply (GCS) transformation case series highlights how over a decade of cultural and digital evolution positioned GCS to meet unprecedented global challenges. In 2011, Michael Ku became the Vice President of GCS and... View Details

May 2025
Supplement

On (B): The Cyclon Spins On

By: Ramon Casadesus-Masanell, Karolin Frankenberger, Sascha Mader and Karen Elterman

A follow-up to the On case (723-430), this short case explores how the performance athletic shoe company On expanded its Cyclon subscription and recycling program through 2024, adding two new shoe models to the subscription and a one-time-purchase recyclable T-shirt. View Details

May 2025
Teaching Note

The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation

By: Tsedal Neeley

Teaching Note for HBS Case No. 425-720. Florian Hillen, co-founder and CEO of VideaHealth, a startup using artificial intelligence (AI) to detect dental conditions on x-rays, spent the early years of his company laying the groundwork for an AI factory. This AI factory,... View Details

Keywords: Diagnostics; Organization Design; Change Management; Disruption; Transformation; Health Care and Treatment; AI and Machine Learning; Technological Innovation; Technology Adoption; Management Style; Organizational Culture; Success; Technology Industry; Health Industry; United States

May 2025
Case

RTX's Lifetime Income Strategy: Shaping the Future of Retirement

By: Daniel Green, Luis M. Viceira and Sarah Mehta

Set in 2024, this case explores the Lifetime Income Strategy (LIS), a novel retirement product launched by aerospace and defense company RTX in 2012. Aiming to embed the security of a traditional pension within a 401(k) plan, the LIS allowed participants to secure a... View Details

Keywords: Asset Management; Compensation and Benefits; Collaborative Innovation and Invention; Jobs and Positions; Labor; Retirement; Society; Adoption; Personal Finance; Aerospace Industry; Financial Services Industry; Insurance Industry; United States; Virginia

May 2025 (Revised May 2025)
Case

Humana Commits to Value-Based Care

By: V.G. Narayanan, Henry Eyring and David Lane

In late 2023, CEO Bruce Broussard reviewed health insurer Humana’s transformation into a value-based care ecosystem. Under its CenterWell brand, the several millions of members in Humana Medicare Advantage plans now had access to Humana-provided primary care, home... View Details

Keywords: Business Model; Business Units; Financing and Loans; Innovation Strategy; Growth and Development Strategy; Service Operations; Mergers and Acquisitions; Insurance; Health Care and Treatment; Partners and Partnerships; Health Industry; Insurance Industry; United States

May 2025
Case

Community First! Village: Scaling Goodness?

By: Jan Rivkin and Coelin P. Scibetta

The nonprofit organization Mobile Loaves & Fishes has devised an innovative way to address chronic homelessness: their Community First! Village provides tiny homes, recreational vehicles, and facilities that bring community, housing, support, and work opportunities to... View Details

Keywords: Nonprofit Organizations; Business Model; Growth and Development Strategy; Expansion; Social Issues; Texas

2025
Chapter

Marjorie Yang Mun Tak 楊梅德：Entrepreneur and Innovator

By: William C. Kirby

BOOK ABSTRACT:
Chinese Encounters with America tells the stories of twelve women and men whose American experiences transformed their lives and influenced China’s trajectory, with a particular focus on the period after Beijing and Washington established... View Details

Keywords: International Relations; Leadership; China

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May 2025
Case

Windsurf and the AI Code Assistant Market

By: Suraj Srinivasan, Sudhanshu Nath Mishra and Radhika Kak

In April 2025, the founding team of Windsurf, an AI start-up specializing in code generation gathered in Mountain View, California, to assess its remarkable year of growth. The company had scaled from a niche GitHub Copilot alternative to a breakout player with over... View Details

Keywords: AI and Machine Learning; Venture Capital; Innovation Leadership; Technological Innovation; Business Growth and Maturation; Competition; Business Strategy; Technology Industry; United States

April 2025 (Revised May 2025)
Case

Adobe: GenAI Opportunity or Threat?

By: Sunil Gupta, Rajiv Lal and Allison Ciechanover

In December 2022, Adobe CEO Shantanu Narayen faced a pivotal strategic decision due to the rapid rise of generative AI image models from OpenAI, Midjourney, and StabilityAI. Adobe, a leader in digital media and marketing software with a 40-year legacy of innovation and... View Details

Keywords: Customer Relationship Management; Ethics; AI and Machine Learning; Trust; Business Strategy; Technology Industry; San Jose

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