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      • April 2025
      • Case

      #FutureFresenius: Implementing a New Strategy to Transform the Company and Advance Patient Care

      By: David J. Collis, Benjamin C. Esty and Haisley Wert
      In February 2024, Fresenius CEO Michael Sen reflected on the company’s transformation journey from his office in Bad Homburg, Germany. With revenues of €22 billion and a mission to advance patient care, Fresenius had built a strong reputation through decades of... View Details
      Keywords: Strategic Planning; Corporate Strategy; Transformation; Finance; Leading Change; Organizational Culture; Organizational Structure; Alignment; Health Industry; Germany; United States
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      Collis, David J., Benjamin C. Esty, and Haisley Wert. "#FutureFresenius: Implementing a New Strategy to Transform the Company and Advance Patient Care." Harvard Business School Case 725-361, April 2025.
      • September 2024
      • Case

      Myeloma Investment Fund

      By: Kyle Myers and Scott Sawaya
      This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.

      The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details
      Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation & Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry
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      Myers, Kyle, and Scott Sawaya. "Myeloma Investment Fund." Harvard Business School Case 625-047, September 2024.
      • April 2024
      • Case

      Michelin in Motion: Putting Purpose to Work

      By: Hubert Joly, Nitin Nohria and Emilie Billaud
      When he became CEO, facing limited growth prospects, a low valuation, and therefore a stagnating share price, Menegaux and his team launched a set of initiatives to reposition Michelin. These included (1) articulating a clear purpose (“We care about giving people a... View Details
      Keywords: Transformation; Talent and Talent Management; Innovation Strategy; Leading Change; Goals and Objectives; Growth and Development Strategy; Management Practices and Processes; Organizational Culture; Identity; Motivation and Incentives; Corporate Strategy; Diversification; Value Creation; Mission and Purpose; Valuation; Manufacturing Industry; Rubber Industry; Transportation Industry; Europe; France
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      Joly, Hubert, Nitin Nohria, and Emilie Billaud. "Michelin in Motion: Putting Purpose to Work." Harvard Business School Case 324-127, April 2024.
      • March 2024 (Revised May 2024)
      • Case

      Amperity: First-Party Data at a Crossroads

      By: Elie Ofek, Hema Yoganarasimhan and Alexis Lefort
      In the summer of 2023, Amperity management was facing a critical decision on its future direction. Given the dramatic changes occurring within the digital advertising ecosystem, as concerns over consumer privacy placed limits on the ability to engage in third-party... View Details
      Keywords: AI and Machine Learning; Technology Adoption; Business Strategy; Digital Marketing; Price; Product; Business or Company Management; Advertising Industry
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      Ofek, Elie, Hema Yoganarasimhan, and Alexis Lefort. "Amperity: First-Party Data at a Crossroads." Harvard Business School Case 524-017, March 2024. (Revised May 2024.)
      • March 2024
      • Teaching Note

      CoPilot(s): Generative AI at Microsoft and GitHub

      By: Frank Nagle and Maria P. Roche
      This teaching note is the companion to case N9-624-010 CoPilot(s): Generative AI at Microsoft and GitHub, which takes place in late 2021. The case briefly describes the history of both GitHub and Microsoft with a particular focus on open source software (OSS)—software... View Details
      Keywords: Mergers and Acquisitions; AI and Machine Learning; Applications and Software; Technological Innovation; Product Launch; Open Source Distribution; Product Development; Commercialization; Competition; Resource Allocation; Technology Industry
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      Nagle, Frank, and Maria P. Roche. "CoPilot(s): Generative AI at Microsoft and GitHub." Harvard Business School Teaching Note 724-452, March 2024.
      • January 19, 2024
      • Article

      Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder

      By: Robert S. Kaplan and Sarah E. Wakeman
      U.S. overdose deaths currently exceed 100,000 per year. New facilities, known as bridge clinics, are broadening access to high-quality care by offering outpatient substance use disorder (SUD) treatment with few access barriers. But many of the critical services offered... View Details
      Keywords: Health Care and Treatment; Cost; Adoption
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      Kaplan, Robert S., and Sarah E. Wakeman. "Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder." Health Affairs Forefront (January 19, 2024).
      • January 2024
      • Background Note

      Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?

      By: Regina E. Herzlinger and James Wallace
      How can we evaluate if innovative health care ventures can do good—benefit society—and do well—become financially viable? This question is the topic of the first module in the Innovating in Health Care course book.

      This note and "Health Stop (A): What Type... View Details
      Keywords: Business Model; Health Care and Treatment; Collaborative Innovation and Invention; Mission and Purpose; Alignment; Health Industry
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      Herzlinger, Regina E., and James Wallace. "Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?" Harvard Business School Background Note 324-037, January 2024.
      • 2023
      • Book

      Workplace Conditions

      By: Jill Maben, Jane Ball and Amy C. Edmondson
      This Element reviews the evidence for three workplace conditions that matter for improving quality and safety in healthcare: staffing; psychological safety, teamwork, and speaking up; and staff health and well-being at work. The authors propose that these are... View Details
      Keywords: Working Conditions; Outcome or Result; Safety; Well-being; Health Industry
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      Maben, Jill, Jane Ball, and Amy C. Edmondson. Workplace Conditions. Cambridge Elements, Improving Quality and Safety in Healthcare. Cambridge University Press, 2023.
      • Winter 2022
      • Article

      Distributing a Billion Vaccines: COVAX Successes, Challenges, and Opportunities

      By: Eric Budish, Hannah Kettler, Scott Duke Kominers, Erik Osland, Canice Prendergast and Andrew A. Torkelson
      By January 2022, the COVAX international vaccine collaboration had allocated over a billion vaccines to over 140 countries. We describe and review the allocation process chosen, which reflected both an objective of equitably distributing vaccines across the world and... View Details
      Keywords: Vaccines; Pandemics; Health Care and Treatment; Health Pandemics; Distribution; Supply Chain; Equality and Inequality
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      Budish, Eric, Hannah Kettler, Scott Duke Kominers, Erik Osland, Canice Prendergast, and Andrew A. Torkelson. "Distributing a Billion Vaccines: COVAX Successes, Challenges, and Opportunities." Oxford Review of Economic Policy 38, no. 4 (Winter 2022): 941–974.
      • 2022
      • Other Unpublished Work

      Got 'Critical Minerals'? Hooray! But Be Careful

      By: Louis T. Wells
      When a country has “critical minerals,” certain issues require special attention in the country’s mining legislation or while negotiating contracts with potential mining investors. As well, to obtain maximum benefit the government should prepare for negotiations with... View Details
      Keywords: Critical Minerals; Foreign Direct Investment; International Relations; Mining Industry
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      Wells, Louis T. "Got 'Critical Minerals'? Hooray! But Be Careful." Columbia FDI Perspectives, No. 338, August 2022.
      • March 2022
      • Article

      Where to Locate COVID-19 Mass Vaccination Facilities?

      By: Dimitris Bertsimas, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li and Alessandro Previero
      The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United States in particular, the new... View Details
      Keywords: Vaccines; COVID-19; Health Care and Treatment; Health Pandemics; Performance Effectiveness; Analytics and Data Science; Mathematical Methods
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      Bertsimas, Dimitris, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li, and Alessandro Previero. "Where to Locate COVID-19 Mass Vaccination Facilities?" Naval Research Logistics Quarterly 69, no. 2 (March 2022): 179–200.
      • 24 Feb 2022
      • Other Presentation

      The Fearless ICU

      By: Amy C. Edmondson
      The last 24 months have pushed ICU teams around the world to their limits. As we move forward, we need to heal and rebuild our critical care teams. Healthcare more than ever will require ICU teams to perform at the highest levels and to continuously innovate to deliver... View Details
      Keywords: Psychological Safety; Teams; Critical Care; Health Care and Treatment; Groups and Teams; Performance Effectiveness
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      "The Fearless ICU." Critical Matters (podcast), Sound Physicians, February 24, 2022.
      • 2021
      • White Paper

      Go Out and Innovate! Perspectives on Educating Health Care Leadership in the Time of Innovation

      By: Regina E. Herzlinger, Anthony Stanowski, Edward Schumacher, Eugene Schneller, Kaveh Safavi, Quint Studer, Andrew Jay, Tom Robinson and Kevin Mahoney
      The CAHME Innovation Council unanimously believes that education is essential. In evaluating the competency domain of management and leadership, and learning from programs that prioritize innovation, we ask how do we develop competencies in future leaders to succeed in... View Details
      Keywords: Health Care; Health Care Industry; Health Care Entrepreneurship; Innovation; Innovation & Entrepreneurship; Health Industry
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      Herzlinger, Regina E., Anthony Stanowski, Edward Schumacher, Eugene Schneller, Kaveh Safavi, Quint Studer, Andrew Jay, Tom Robinson, and Kevin Mahoney. "Go Out and Innovate! Perspectives on Educating Health Care Leadership in the Time of Innovation." White Paper, Commission on Accreditation of Healthcare Management Education (CAHME), November 2021.
      • October 2021 (Revised February 2022)
      • Case

      Hospital 57357: Aligning Performance Towards a Vision of a Cancer-Free Childhood

      By: Susanna Gallani and Youssef Abdel Aal
      The case follows the Children Cancer Hospital in Egypt, also known as Hospital 57357, as it goes through the roll-out of a new performance management system, which Dr. Sherif Abouel Naga, founder and CEO of the hospital, had championed. This was a critical juncture as... View Details
      Keywords: Healthcare; Performance Management; Performance Incentives; Strategic Alignment; Health Care and Treatment; Nonprofit Organizations; Strategy; Alignment; Performance Evaluation; Mission and Purpose; Change Management; Health Industry; Egypt; Middle East
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      Gallani, Susanna, and Youssef Abdel Aal. "Hospital 57357: Aligning Performance Towards a Vision of a Cancer-Free Childhood." Harvard Business School Case 122-041, October 2021. (Revised February 2022.)
      • October 13, 2021
      • Editorial

      How Companies Can Improve Employee Engagement Right Now

      By: Daniel Stein, Nick Hobson, Jon M. Jachimowicz and Ashley Whillans
      A year and a half into the pandemic, employees’ mental “surge capacity” is likely diminished. Managers must take proactive steps to increase employee engagement, or risk losing their workforce. Engaged employees perform better, experience less burnout, and stay in... View Details
      Keywords: Employee Retention; Employee Engagement; Employee Relationship Management; Work-Life Balance
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      Stein, Daniel, Nick Hobson, Jon M. Jachimowicz, and Ashley Whillans. "How Companies Can Improve Employee Engagement Right Now." Harvard Business Review (website) (October 13, 2021).
      • May 2021
      • Article

      Value-Based Healthcare in Urology: A Collaborative Review

      By: Chanan Reitblat, Paul A. Bain, Michael E. Porter, David N. Bernstein, Thomas W. Feeley, Markus Graefen, Santosh Iyer, Matthew J. Resnick, C.J. Stimson, Quoc-Dien Trinh and Boris Gershman
      Context:
      In response to growing concerns over rising costs and major variation in quality, improving value for patients has been proposed as a fundamentally new strategy for how healthcare should be delivered, measured, and... View Details
      Keywords: Value-based Healthcare; Integrated Practice Units; Outcome Measurement; Time-Driven Activity-Based Costing; Health Care and Treatment; Value; Cost Management; Strategy; Outcome or Result; Measurement and Metrics
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      Reitblat, Chanan, Paul A. Bain, Michael E. Porter, David N. Bernstein, Thomas W. Feeley, Markus Graefen, Santosh Iyer, Matthew J. Resnick, C.J. Stimson, Quoc-Dien Trinh, and Boris Gershman. "Value-Based Healthcare in Urology: A Collaborative Review." European Urology 79, no. 5 (May 2021): 571–585.
      • 2021
      • Other Unpublished Work

      As Healthcare Costs Escalate, A New George and Regi Herzlinger Industry Award Shines a Spotlight on Innovation Education

      By: Regina E. Herzlinger
      The winners of the first ever CAHME/George and Regi Herzlinger Innovation Education Award have just been announced. Regi Herzlinger explains why rewarding, supporting, and encouraging innovation education is so critical to solving the challenges of our industry. View Details
      Keywords: Health Care and Treatment; Management; Innovation and Invention; Education
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      "As Healthcare Costs Escalate, A New George and Regi Herzlinger Industry Award Shines a Spotlight on Innovation Education." Commission on Accreditation of Healthcare Management Education (CAHME), March 2021.
      • Article

      Treatment Of Opioid Use Disorder Among Commercially Insured U.S. Adults, 2008–17

      By: Karen Shen, Eric Barrette and Leemore S. Dafny
      There is abundant literature on efforts to reduce opioid prescriptions and misuse, but comparatively little on the treatment provided to people with opioid use disorder (OUD). Using claims data representing 12–15 million nonelderly adults covered through commercial... View Details
      Keywords: Opioid Treatment; Medication-assisted Treatment; Substance Use Disorder; Private Insurance; Health Disorders; Health Care and Treatment; Insurance; United States
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      Shen, Karen, Eric Barrette, and Leemore S. Dafny. "Treatment Of Opioid Use Disorder Among Commercially Insured U.S. Adults, 2008–17." Health Affairs 39, no. 6 (June 2020): 993–1001.
      • Article

      Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting

      By: Raymond H. Mak, Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani and Eva C. Guinan
      Importance: Radiation therapy (RT) is a critical cancer treatment, but the existing radiation oncologist work force does not meet growing global demand. One key physician task in RT planning involves tumor segmentation for targeting, which requires substantial... View Details
      Keywords: Crowdsourcing; AI Algorithms; Health Care and Treatment; Collaborative Innovation and Invention; AI and Machine Learning
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      Mak, Raymond H., Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani, and Eva C. Guinan. "Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting." JAMA Oncology 5, no. 5 (May 2019): 654–661.
      • January 2019 (Revised February 2024)
      • Teaching Note

      Hubble Contact Lenses: Data Driven Direct-to-Consumer Marketing

      By: Ayelet Israeli
      Teaching Note for HBS No. 519-011. As its Series A extension round approaches, the founders of Hubble, a subscription-based, social-media fueled, direct-to-consumer (DTC) brand of contact lenses, are reflecting on the marketing strategies that have taken them to a... View Details
      Keywords: DTC; Direct To Consumer Marketing; Health Care; Mobile; Attribution; Experimentation; Experiments; Churn/retention; Customer Lifetime Value; Internet Marketing; Big Data; Analytics; A/B Testing; CRM; Advertising; Marketing; Marketing Channels; Marketing Strategy; Media; Brands and Branding; Marketing Communications; Digital Marketing; Acquisition; Growth and Development Strategy; Customer Focus and Relationships; Consumer Behavior; Social Media; E-commerce
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      Israeli, Ayelet. "Hubble Contact Lenses: Data Driven Direct-to-Consumer Marketing." Harvard Business School Teaching Note 519-056, January 2019. (Revised February 2024.)
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