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      • April 2025
      • Teaching Note

      ZEISS: Commercializing Science

      By: Maria P. Roche
      Teaching Note for HBS Case No. 725-359. View Details
      Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
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      Roche, Maria P. "ZEISS: Commercializing Science." Harvard Business School Teaching Note 725-458, April 2025.
      • April 2025
      • Supplement

      ZEISS: Commercializing Science

      By: Maria P. Roche and Richie Zitomer
      Spreadsheet Supplement for HBS Case No. 725-359. View Details
      Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
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      Roche, Maria P., and Richie Zitomer. "ZEISS: Commercializing Science." Harvard Business School Spreadsheet Supplement 725-856, April 2025.
      • 2025
      • Working Paper

      The Cybernetic Teammate: A Field Experiment on Generative AI Reshaping Teamwork and Expertise

      By: Fabrizio Dell'Acqua, Charles Ayoubi, Hila Lifshitz, Raffaella Sadun, Ethan Mollick, Lilach Mollick, Yi Han, Jeff Goldman, Hari Nair, Stew Taub and Karim R. Lakhani
      We examine how artificial intelligence transforms the core pillars of collaboration— performance, expertise sharing, and social engagement—through a pre-registered field experiment with 776 professionals at Procter & Gamble, a global consumer packaged goods company.... View Details
      Keywords: Artificial Intelligence; Teamwork; Human-machine Interaction; Productivity; Skills; Innovation; Field Experiment; AI and Machine Learning; Groups and Teams; Competency and Skills; Performance Productivity; Collaborative Innovation and Invention; Product Development
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      Dell'Acqua, Fabrizio, Charles Ayoubi, Hila Lifshitz, Raffaella Sadun, Ethan Mollick, Lilach Mollick, Yi Han, Jeff Goldman, Hari Nair, Stew Taub, and Karim R. Lakhani. "The Cybernetic Teammate: A Field Experiment on Generative AI Reshaping Teamwork and Expertise." Harvard Business School Working Paper, No. 25-043, March 2025.
      • March 2025
      • Case

      Metaphysic AI: Rethinking the Value of Human Expertise

      By: Zoë B. Cullen, Shikhar Ghosh and Shweta Bagai
      In early 2025, Thomas Graham, CEO of Metaphysic, a leading AI generative video company confronted fundamental questions about who should control digital identity in a world where AI could perfectly recreate human likeness. Founded in 2021, Metaphysic first rose to fame... View Details
      Keywords: Business Model; Ethics; AI and Machine Learning; Intellectual Property; Rights; Negotiation; Value; Motion Pictures and Video Industry; Technology Industry
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      Cullen, Zoë B., Shikhar Ghosh, and Shweta Bagai. "Metaphysic AI: Rethinking the Value of Human Expertise." Harvard Business School Case 825-146, March 2025.
      • February 2025
      • Case

      Abiomed: Clinical Trials and Tribulations

      By: Satish Tadikonda, Faith Robertson and William Marks
      After receiving 510(k) clearance for the Impella 2.5 device, Abiomed had proceeded to conduct a premarket approval (PMA) process as well to prove clinical superiority, earn greater protection, and extend commercial runway. However, in the middle of the clinical trial... View Details
      Keywords: Corporate Disclosure; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Medical Devices and Supplies Industry
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      Tadikonda, Satish, Faith Robertson, and William Marks. "Abiomed: Clinical Trials and Tribulations." Harvard Business School Case 825-096, February 2025.
      • January 2025
      • Case

      Davivienda Bank's Upskilling and Reskilling Strategy in Colombia (Abridged)

      By: Jorge Tamayo, Raffaella Sadun and Jenyfeer Martinez Buitrago
      Set in 2022, this abridged case examines the digital transformation strategy of Davivienda—a leading player in Colombia’s commercial banking sector and one of the companies belonging to Grupo Bolívar, a major Colombian conglomerate—and the bank’s upskilling and... View Details
      Keywords: Change Management; Transformation; Decision Choices and Conditions; Digital Strategy; Digital Transformation; Internet and the Web; Mobile and Wireless Technology; Innovation and Management; Innovation Strategy; Growth and Development Strategy; Business Strategy; Corporate Strategy; Talent and Talent Management; Training; Organizational Culture; Banking Industry; Latin America; Central America; South America; Colombia
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      Tamayo, Jorge, Raffaella Sadun, and Jenyfeer Martinez Buitrago. "Davivienda Bank's Upskilling and Reskilling Strategy in Colombia (Abridged)." Harvard Business School Case 725-428, January 2025.
      • January 2025 (Revised April 2025)
      • Case

      Blue Frontier: Disrupting Air Conditioning

      By: Rosabeth Moss Kanter and Jacob A. Small
      Serial entrepreneur Daniel Betts founded Blue Frontier in South Florida to offer a climate-friendly solution to increase air conditioning efficiency and dehumidify using new technology he developed. Backed by significant venture capital, Blue Frontier had to choose... View Details
      Keywords: Entrepreneurship; Climate Change; Environmental Sustainability; Technological Innovation; Market Entry and Exit; Performance Efficiency; Business Strategy; Florida
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      Kanter, Rosabeth Moss, and Jacob A. Small. "Blue Frontier: Disrupting Air Conditioning." Harvard Business School Case 325-088, January 2025. (Revised April 2025.)
      • January 2025
      • Case

      Jaipur Literature Festival 2024

      By: Tarun Khanna and Kanika Jain
      The Jaipur Literature Festival had evolved from a modest gathering in 2006 into one of the world’s most significant literary events. It was known for its principle of egalitarian access, allowing people from various social backgrounds to come together and engage with... View Details
      Keywords: Arts; Cultural Entrepreneurship; Leadership; Business or Company Management; Media; Business Strategy; Expansion; Profit; Product Positioning; Asia; South Asia
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      Khanna, Tarun, and Kanika Jain. "Jaipur Literature Festival 2024." Harvard Business School Case 725-420, January 2025.
      • December 2024
      • Case

      Xtalic

      By: Joshua Lev Krieger and Jim Matheson
      This case study examines the commercialization efforts of Xtalic, a startup founded by MIT scientists based on their discovery of a novel material science method to protect metal substrates. The case focuses on the strategic decisions involved in bringing this... View Details
      Keywords: Entrepreneurship; Finance; Innovation & Entrepreneurship; Innovation and Management; Entrepreneurial Finance
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      Krieger, Joshua Lev, and Jim Matheson. "Xtalic." Harvard Business School Case 825-103, December 2024.
      • 2024
      • Working Paper

      Charting (and Updating) the Path: A Bayesian Perspective on Entrepreneurial Learning

      By: Joshua L. Krieger
      This chapter explores two distinct modes of entrepreneurial learning: assessing venture viability and choosing between alternative development paths. It introduces a framework for decomposing venture viability into technological feasibility, commercial potential and... View Details
      Keywords: Decision Making; Entrepreneurship; Growth and Development Strategy; Learning
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      Krieger, Joshua L. "Charting (and Updating) the Path: A Bayesian Perspective on Entrepreneurial Learning." Harvard Business School Working Paper, No. 25-031, December 2024.
      • 2024
      • Working Paper

      Catalysts for Climate Solutions: Corporate Responses to Venture Capital Financing of Climate-tech Startups

      By: Shirley Lu, George Serafeim and Simon Xu
      We study whether incumbent firms increase their product focus on climate solutions in response to venture capital (VC) financing of climate-tech startups. Using large language models to measure a firm's focus on climate solutions, we find that incumbents in similar... View Details
      Keywords: Climate Finance; Climate Change; Technological Innovation; Entrepreneurship; Venture Capital; Private Equity; Environmental Sustainability; Business Startups
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      Lu, Shirley, George Serafeim, and Simon Xu. "Catalysts for Climate Solutions: Corporate Responses to Venture Capital Financing of Climate-tech Startups." Harvard Business School Working Paper, No. 25-025, November 2024.
      • October 2024
      • Module Note

      Purpose of the Firm

      By: Debora L. Spar and Julia M. Comeau
      Purpose of the Firm (PoF) is a short module designed to explore how, and under what circumstances, business leaders can harness the power of capitalism and markets to “make a difference in the world”—that is, to address a significant societal problem as a commercial... View Details
      Keywords: Social Accounting; Purpose; Corporate Social Responsibility and Impact; Social Enterprise; Mission and Purpose; Leadership
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      Spar, Debora L., and Julia M. Comeau. "Purpose of the Firm." Harvard Business School Module Note 325-035, October 2024.
      • October 2024
      • Article

      Medicare Part D Protected-Class Policy Is Associated with Lower Drug Rebates

      By: Pragya Kakani, Michael Anne Kyle, Amitabh Chandra and Luca Maini
      Medicare Part D does not allow plans to exclude drugs in six protected classes from their formularies, which may limit plans’ ability to negotiate rebates and lead to higher spending. We estimated the association between protected-class status, US-level estimated... View Details
      Keywords: Insurance; Health Care and Treatment; Governing Rules, Regulations, and Reforms; United States
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      Kakani, Pragya, Michael Anne Kyle, Amitabh Chandra, and Luca Maini. "Medicare Part D Protected-Class Policy Is Associated with Lower Drug Rebates." Health Affairs 43, no. 10 (October 2024): 1420–1427.
      • October 2024
      • Article

      Sampling Bias in Entrepreneurial Experiments

      By: Ruiqing Cao, Rembrand Koning and Ramana Nanda
      Using data from a prominent online platform for launching new digital products, we document that ‘sampling bias’—defined as the difference between a startup’s target customer base and the actual sample on which early ‘beta tests’ are conducted—has a systematic and... View Details
      Keywords: Target Market; Sampling Biases; Beta Testing; Product Launch; Entrepreneurship; Gender
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      Cao, Ruiqing, Rembrand Koning, and Ramana Nanda. "Sampling Bias in Entrepreneurial Experiments." Management Science 70, no. 10 (October 2024): 7283–7307.
      • 2024
      • Working Paper

      The New Digital Divide

      By: Mayana Pereira, Shane Greenstein, Raffaella Sadun, Prasanna Tambe, Lucia Ronchi Darre, Tammy Glazer, Allen Kim, Rahul Dodhia and Juan Lavista Ferres
      We build and analyze new metrics of digital usage that leverage telemetry data collected by Microsoft during operating system updates across forty million Windows devices in U.S. households. These measures of US household digital usage are much more comprehensive than... View Details
      Keywords: Mathematical Methods; Measurement and Metrics; Geographic Location; Behavior; Technology Adoption; Demographics
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      Pereira, Mayana, Shane Greenstein, Raffaella Sadun, Prasanna Tambe, Lucia Ronchi Darre, Tammy Glazer, Allen Kim, Rahul Dodhia, and Juan Lavista Ferres. "The New Digital Divide." NBER Working Paper Series, No. 32932, September 2024.
      • August 2024
      • Case

      Iogen: Decarbonizing Hard-to-Abate Sectors

      By: George Serafeim, Charlotte Foody and John Mulliken
      Brian Foody, CEO of Iogen Corporation, was an early leader in advanced biofuels, developing a range of technologies to transform agricultural waste into transportation fuel. With $100 million in revenue and 350 patents across various biofuel technologies, Iogen was... View Details
      Keywords: Technology; Biofuel; Market Attractiveness; Decarbonization; Technological Innovation; Climate Change; Energy; Environmental Sustainability; Transformation; Market Entry and Exit; Strategy; Energy Industry; United States; United Kingdom
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      Serafeim, George, Charlotte Foody, and John Mulliken. "Iogen: Decarbonizing Hard-to-Abate Sectors." Harvard Business School Case 125-037, August 2024.
      • August 2024 (Revised November 2024)
      • Case

      Commonwealth Fusion Systems: Born at Scale

      By: Joshua Lev Krieger, Jim Matheson, Kyle Myers, Gunnar Trumbull and Richard Vietor
      This case study chronicles the journey of Commonwealth Fusion Systems (CFS) on its ambitious mission to commercialize fusion energy and become the world’s leading provider of fusion power plants. Emerging from a “special arrangement” with MIT's Plasma Science and... View Details
      Keywords: Nuclear Energy; Innovation; Entrepreneurship; Entrepreneurial Finance; Energy Generation; Commercialization; Science-Based Business; Technological Innovation; Market Entry and Exit; Energy Industry
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      Krieger, Joshua Lev, Jim Matheson, Kyle Myers, Gunnar Trumbull, and Richard Vietor. "Commonwealth Fusion Systems: Born at Scale." Harvard Business School Case 825-061, August 2024. (Revised November 2024.)
      • August 2024
      • Article

      How Do Copayment Coupons Affect Branded Drug Prices and Quantities Purchased?

      By: Leemore S. Dafny, Kate Ho and Edward Kong
      Drug copayment coupons to reduce patient cost-sharing have become nearly ubiquitous for high-priced brand-name prescription drugs. Medicare bans such coupons on the grounds that they are kickbacks that induce utilization, but they are commonly used by... View Details
      Keywords: Prescription Drugs; Coupons; Impact; Health Care and Treatment; Markets; Price; Spending; Pharmaceutical Industry; United States
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      Dafny, Leemore S., Kate Ho, and Edward Kong. "How Do Copayment Coupons Affect Branded Drug Prices and Quantities Purchased?" American Economic Journal: Economic Policy 16, no. 3 (August 2024): 314–346.
      • July 2024
      • Case

      RMZ 4.0: 'How Fast Do We Want to Run?'

      By: Boris Groysberg and Sarah L. Abbott
      In 2023, RMZ Corporation (“RMZ”) a large family-owned real estate firm based in Bengaluru, India, announced plans to transform from a commercial real estate developer to a diversified alternative asset owner. Over the next 5 years, RMZ looked to grow its real estate... View Details
      Keywords: International Expansion; Growth Management; Family Business; Talent and Talent Management; Goals and Objectives; Transformation; Growth and Development Strategy; Diversification; Change Management; Global Strategy; Organizational Change and Adaptation; Real Estate Industry; India
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      Groysberg, Boris, and Sarah L. Abbott. "RMZ 4.0: 'How Fast Do We Want to Run?'." Harvard Business School Case 425-010, July 2024.
      • July 2024
      • Case

      ZEISS: Commercializing Science

      By: Maria P. Roche, Carlota Moniz and Daniela Beyersdorfer
      Karl Lamprecht, President and CEO of the ZEISS AG Group, mused on how far ZEISS had come in 175 years of being a pioneer in optics, and how the course he had charted since taking the helm of the company could keep it on track. In his role, he oversaw the four core... View Details
      Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
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      Roche, Maria P., Carlota Moniz, and Daniela Beyersdorfer. "ZEISS: Commercializing Science." Harvard Business School Case 725-359, July 2024.
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