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- April 2025
- Teaching Note
ZEISS: Commercializing Science
By: Maria P. Roche
Teaching Note for HBS Case No. 725-359. View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
- April 2025
- Supplement
ZEISS: Commercializing Science
By: Maria P. Roche and Richie Zitomer
Spreadsheet Supplement for HBS Case No. 725-359. View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
- 2025
- Working Paper
The Cybernetic Teammate: A Field Experiment on Generative AI Reshaping Teamwork and Expertise
By: Fabrizio Dell'Acqua, Charles Ayoubi, Hila Lifshitz, Raffaella Sadun, Ethan Mollick, Lilach Mollick, Yi Han, Jeff Goldman, Hari Nair, Stew Taub and Karim R. Lakhani
We examine how artificial intelligence transforms the core pillars of collaboration—
performance, expertise sharing, and social engagement—through a pre-registered field
experiment with 776 professionals at Procter & Gamble, a global consumer packaged goods
company.... View Details
Keywords: Artificial Intelligence; Teamwork; Human-machine Interaction; Productivity; Skills; Innovation; Field Experiment; AI and Machine Learning; Groups and Teams; Competency and Skills; Performance Productivity; Collaborative Innovation and Invention; Product Development
Dell'Acqua, Fabrizio, Charles Ayoubi, Hila Lifshitz, Raffaella Sadun, Ethan Mollick, Lilach Mollick, Yi Han, Jeff Goldman, Hari Nair, Stew Taub, and Karim R. Lakhani. "The Cybernetic Teammate: A Field Experiment on Generative AI Reshaping Teamwork and Expertise." Harvard Business School Working Paper, No. 25-043, March 2025.
- March 2025
- Case
Metaphysic AI: Rethinking the Value of Human Expertise
By: Zoë B. Cullen, Shikhar Ghosh and Shweta Bagai
In early 2025, Thomas Graham, CEO of Metaphysic, a leading AI generative video company confronted fundamental questions about who should control digital identity in a world where AI could perfectly recreate human likeness. Founded in 2021, Metaphysic first rose to fame... View Details
Keywords: Business Model; Ethics; AI and Machine Learning; Intellectual Property; Rights; Negotiation; Value; Motion Pictures and Video Industry; Technology Industry
Cullen, Zoë B., Shikhar Ghosh, and Shweta Bagai. "Metaphysic AI: Rethinking the Value of Human Expertise." Harvard Business School Case 825-146, March 2025.
- February 2025
- Case
Abiomed: Clinical Trials and Tribulations
By: Satish Tadikonda, Faith Robertson and William Marks
After receiving 510(k) clearance for the Impella 2.5 device, Abiomed had proceeded to conduct a premarket approval (PMA) process as well to prove clinical superiority, earn greater protection, and extend commercial runway. However, in the middle of the clinical trial... View Details
Keywords: Corporate Disclosure; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Medical Devices and Supplies Industry
Tadikonda, Satish, Faith Robertson, and William Marks. "Abiomed: Clinical Trials and Tribulations." Harvard Business School Case 825-096, February 2025.
- January 2025
- Case
Davivienda Bank's Upskilling and Reskilling Strategy in Colombia (Abridged)
By: Jorge Tamayo, Raffaella Sadun and Jenyfeer Martinez Buitrago
Set in 2022, this abridged case examines the digital transformation strategy of Davivienda—a leading player in Colombia’s commercial banking sector and one of the companies belonging to Grupo Bolívar, a major Colombian conglomerate—and the bank’s upskilling and... View Details
Keywords: Change Management; Transformation; Decision Choices and Conditions; Digital Strategy; Digital Transformation; Internet and the Web; Mobile and Wireless Technology; Innovation and Management; Innovation Strategy; Growth and Development Strategy; Business Strategy; Corporate Strategy; Talent and Talent Management; Training; Organizational Culture; Banking Industry; Latin America; Central America; South America; Colombia
Tamayo, Jorge, Raffaella Sadun, and Jenyfeer Martinez Buitrago. "Davivienda Bank's Upskilling and Reskilling Strategy in Colombia (Abridged)." Harvard Business School Case 725-428, January 2025.
- January 2025 (Revised April 2025)
- Case
Blue Frontier: Disrupting Air Conditioning
By: Rosabeth Moss Kanter and Jacob A. Small
Serial entrepreneur Daniel Betts founded Blue Frontier in South Florida to offer a climate-friendly solution to increase air conditioning efficiency and dehumidify using new technology he developed. Backed by significant venture capital, Blue Frontier had to choose... View Details
Keywords: Entrepreneurship; Climate Change; Environmental Sustainability; Technological Innovation; Market Entry and Exit; Performance Efficiency; Business Strategy; Florida
Kanter, Rosabeth Moss, and Jacob A. Small. "Blue Frontier: Disrupting Air Conditioning." Harvard Business School Case 325-088, January 2025. (Revised April 2025.)
- January 2025
- Case
Jaipur Literature Festival 2024
By: Tarun Khanna and Kanika Jain
The Jaipur Literature Festival had evolved from a modest gathering in 2006 into one of the world’s most significant literary events. It was known for its principle of egalitarian access, allowing people from various social backgrounds to come together and engage with... View Details
Keywords: Arts; Cultural Entrepreneurship; Leadership; Business or Company Management; Media; Business Strategy; Expansion; Profit; Product Positioning; Asia; South Asia
Khanna, Tarun, and Kanika Jain. "Jaipur Literature Festival 2024." Harvard Business School Case 725-420, January 2025.
- December 2024
- Case
Xtalic
By: Joshua Lev Krieger and Jim Matheson
This case study examines the commercialization efforts of Xtalic, a startup founded by MIT scientists based on their discovery of a novel material science method to protect metal substrates. The case focuses on the strategic decisions involved in bringing this... View Details
- 2024
- Working Paper
Charting (and Updating) the Path: A Bayesian Perspective on Entrepreneurial Learning
This chapter explores two distinct modes of entrepreneurial learning: assessing
venture viability and choosing between alternative development paths. It introduces
a framework for decomposing venture viability into technological feasibility, commercial
potential and... View Details
Krieger, Joshua L. "Charting (and Updating) the Path: A Bayesian Perspective on Entrepreneurial Learning." Harvard Business School Working Paper, No. 25-031, December 2024.
- 2024
- Working Paper
Catalysts for Climate Solutions: Corporate Responses to Venture Capital Financing of Climate-tech Startups
By: Shirley Lu, George Serafeim and Simon Xu
We study whether incumbent firms increase their product focus on climate solutions in response to venture capital (VC) financing of climate-tech startups. Using large language models to measure a firm's focus on climate solutions, we find that incumbents in similar... View Details
Keywords: Climate Finance; Climate Change; Technological Innovation; Entrepreneurship; Venture Capital; Private Equity; Environmental Sustainability; Business Startups
Lu, Shirley, George Serafeim, and Simon Xu. "Catalysts for Climate Solutions: Corporate Responses to Venture Capital Financing of Climate-tech Startups." Harvard Business School Working Paper, No. 25-025, November 2024.
- October 2024
- Module Note
Purpose of the Firm
By: Debora L. Spar and Julia M. Comeau
Purpose of the Firm (PoF) is a short module designed to explore how, and under what circumstances, business leaders can harness the power of capitalism and markets to “make a difference in the world”—that is, to address a significant societal problem as a commercial... View Details
Keywords: Social Accounting; Purpose; Corporate Social Responsibility and Impact; Social Enterprise; Mission and Purpose; Leadership
Spar, Debora L., and Julia M. Comeau. "Purpose of the Firm." Harvard Business School Module Note 325-035, October 2024.
- October 2024
- Article
Medicare Part D Protected-Class Policy Is Associated with Lower Drug Rebates
By: Pragya Kakani, Michael Anne Kyle, Amitabh Chandra and Luca Maini
Medicare Part D does not allow plans to exclude drugs in six protected classes from their formularies, which may limit plans’ ability to negotiate rebates and lead to higher spending. We estimated the association between protected-class status, US-level estimated... View Details
Keywords: Insurance; Health Care and Treatment; Governing Rules, Regulations, and Reforms; United States
Kakani, Pragya, Michael Anne Kyle, Amitabh Chandra, and Luca Maini. "Medicare Part D Protected-Class Policy Is Associated with Lower Drug Rebates." Health Affairs 43, no. 10 (October 2024): 1420–1427.
- October 2024
- Article
Sampling Bias in Entrepreneurial Experiments
By: Ruiqing Cao, Rembrand Koning and Ramana Nanda
Using data from a prominent online platform for launching new digital products, we document that ‘sampling bias’—defined as the difference between a startup’s target customer base and the actual sample on which early ‘beta tests’ are conducted—has a systematic and... View Details
Cao, Ruiqing, Rembrand Koning, and Ramana Nanda. "Sampling Bias in Entrepreneurial Experiments." Management Science 70, no. 10 (October 2024): 7283–7307.
- 2024
- Working Paper
The New Digital Divide
By: Mayana Pereira, Shane Greenstein, Raffaella Sadun, Prasanna Tambe, Lucia Ronchi Darre, Tammy Glazer, Allen Kim, Rahul Dodhia and Juan Lavista Ferres
We build and analyze new metrics of digital usage that leverage telemetry data collected by Microsoft during operating system updates across forty million Windows devices in U.S. households. These measures of US household digital usage are much more comprehensive than... View Details
Keywords: Mathematical Methods; Measurement and Metrics; Geographic Location; Behavior; Technology Adoption; Demographics
Pereira, Mayana, Shane Greenstein, Raffaella Sadun, Prasanna Tambe, Lucia Ronchi Darre, Tammy Glazer, Allen Kim, Rahul Dodhia, and Juan Lavista Ferres. "The New Digital Divide." NBER Working Paper Series, No. 32932, September 2024.
- August 2024
- Case
Iogen: Decarbonizing Hard-to-Abate Sectors
By: George Serafeim, Charlotte Foody and John Mulliken
Brian Foody, CEO of Iogen Corporation, was an early leader in advanced biofuels, developing a range of technologies to transform agricultural waste into transportation fuel. With $100 million in revenue and 350 patents across various biofuel technologies, Iogen was... View Details
Keywords: Technology; Biofuel; Market Attractiveness; Decarbonization; Technological Innovation; Climate Change; Energy; Environmental Sustainability; Transformation; Market Entry and Exit; Strategy; Energy Industry; United States; United Kingdom
Serafeim, George, Charlotte Foody, and John Mulliken. "Iogen: Decarbonizing Hard-to-Abate Sectors." Harvard Business School Case 125-037, August 2024.
- August 2024 (Revised November 2024)
- Case
Commonwealth Fusion Systems: Born at Scale
This case study chronicles the journey of Commonwealth Fusion Systems (CFS) on its ambitious mission to commercialize fusion energy and become the world’s leading provider of fusion power plants. Emerging from a “special arrangement” with MIT's Plasma Science and... View Details
Keywords: Nuclear Energy; Innovation; Entrepreneurship; Entrepreneurial Finance; Energy Generation; Commercialization; Science-Based Business; Technological Innovation; Market Entry and Exit; Energy Industry
Krieger, Joshua Lev, Jim Matheson, Kyle Myers, Gunnar Trumbull, and Richard Vietor. "Commonwealth Fusion Systems: Born at Scale." Harvard Business School Case 825-061, August 2024. (Revised November 2024.)
- August 2024
- Article
How Do Copayment Coupons Affect Branded Drug Prices and Quantities Purchased?
By: Leemore S. Dafny, Kate Ho and Edward Kong
Drug copayment coupons to reduce patient cost-sharing have become nearly ubiquitous for high-priced brand-name prescription drugs. Medicare bans such coupons on the grounds that they are kickbacks that induce utilization, but they are commonly used by... View Details
Keywords: Prescription Drugs; Coupons; Impact; Health Care and Treatment; Markets; Price; Spending; Pharmaceutical Industry; United States
Dafny, Leemore S., Kate Ho, and Edward Kong. "How Do Copayment Coupons Affect Branded Drug Prices and Quantities Purchased?" American Economic Journal: Economic Policy 16, no. 3 (August 2024): 314–346.
- July 2024
- Case
RMZ 4.0: 'How Fast Do We Want to Run?'
By: Boris Groysberg and Sarah L. Abbott
In 2023, RMZ Corporation (“RMZ”) a large family-owned real estate firm based in Bengaluru, India, announced plans to transform from a commercial real estate developer to a diversified alternative asset owner. Over the next 5 years, RMZ looked to grow its real estate... View Details
Keywords: International Expansion; Growth Management; Family Business; Talent and Talent Management; Goals and Objectives; Transformation; Growth and Development Strategy; Diversification; Change Management; Global Strategy; Organizational Change and Adaptation; Real Estate Industry; India
Groysberg, Boris, and Sarah L. Abbott. "RMZ 4.0: 'How Fast Do We Want to Run?'." Harvard Business School Case 425-010, July 2024.
- July 2024
- Case
ZEISS: Commercializing Science
By: Maria P. Roche, Carlota Moniz and Daniela Beyersdorfer
Karl Lamprecht, President and CEO of the ZEISS AG Group, mused on how far ZEISS had come in 175 years of being a pioneer in optics, and how the course he had charted since taking the helm of the company could keep it on track. In his role, he oversaw the four core... View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
Roche, Maria P., Carlota Moniz, and Daniela Beyersdorfer. "ZEISS: Commercializing Science." Harvard Business School Case 725-359, July 2024.