Publications

Article

Trends and Predictors of Biomedical Research Quality, 1990–2015: A Meta-Research Study

By: Maryaline Catillon

Keywords: Biomedical Research; R＆D; Innovation; Technology; Drug Trials; RCT; Health; Healthcare; Health Care And Treatment; Health Care Policy; Innovation and Invention; Innovation Strategy; Research and Development; Technological Innovation; Health Industry; Pharmaceutical Industry

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Forthcoming
Article

How Important Is Editorial Gatekeeping? Evidence from Top Biomedical Journals

By: Joshua L. Krieger, Kyle R. Myers and Ariel D. Stern

We examine editors' influence on the scientific content of academic journals by unpacking the role of three major forces: journals' missions, aggregate supply of and demand for specific topics, and scientific homophily via editorial gatekeeping. In a sample of top... View Details

Keywords: Editors; Biomedical Research; Editorial Gatekeeping; Scientific Homophily; Intellectual Capital; Mission and Purpose; Journals and Magazines; Intellectual Property; Innovation and Invention; Human Capital; Higher Education; Publishing Industry

December 2012 (Revised August 2013)
Case

BMS-Biocon Research Center: Growing a Joint Research Venture in India

By: Vicki Sato, Sen Chai, Rich Ballenger, Christine Chi, Alexander Down and Ross Leimberg

Bristol Myers Squibb, a multi-national pharmaceutical company, is seeking to globalize its R&D strategy while managing costs. It has formed a joint venture with an Indian company, which has worked well, but now faces a strategic decision on how and whether to continue. View Details

Keywords: Pharmaceuticals; Global Innovation; Research And Development; Biomedical Research; Joint Ventures; India; United States

November 2011 (Revised February 2012)
Case

China Novartis Institute for Biomedical Research: Building a Sustainable, Globally Integrated Research Enterprise

By: Vicki Sato, Christoph Jaeker and Pooja Mehta Solanki

As the head of the Novartis Institute for Biomedical Research in China, En Li was shepherding a $1 billion R&D investment in China. So far he had been able to attract a large number of Chinese-born but US-trained scientists to play a critical role in establishing the... View Details

Keywords: Globalized Firms and Management; Research; Corporate Strategy; Pharmaceutical Industry; Health Industry; China

2021
Working Paper

Who Do We Invent for? Patents by Women Focus More on Women's Health, but Few Women Get to Invent

By: Rembrand Koning, Sampsa Samila and John-Paul Ferguson

Has the increase in female medical researchers led to more medical advances for women? In this paper, we investigate if the gender of inventors shapes their types of inventions. Using data on the universe of U.S. biomedical patents, we find that patents with women... View Details

Keywords: Innovation; Biomedical Research; Innovation and Invention; Diversity; Gender; Research; Health; United States

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November 2002
Compilation

Four Principles of Biomedical Ethics: Definitions and Examples

By: Sandra J. Sucher

Introduces four principles of biomedical ethics, excerpted from Principles of Biomedical Ethics, Tom L. Beauchamp and James F. Childress (Oxford University Press, 2001). The principles provide a conceptual framework for the analysis and resolution of moral problems... View Details

Keywords: Framework; Moral Sensibility; Health Care and Treatment; Distribution; Problems and Challenges; Research; Emotions; Management Analysis, Tools, and Techniques; Pharmaceutical Industry; Health Industry

June 2008
Case

Gordon Williams: Clinical Research at Brigham and Women's Hospital

By: H. Kent Bowen and Courtney Purrington

Clinical research is a critical element of biomedical research and development. This case describes the challenges of clinical research, and its role in bringing breakthroughs to patients. Dr. Williams leads through his own research and special programs to train... View Details

Keywords: Training; Health Care and Treatment; Success; Programs; Research and Development; Biotechnology Industry; Health Industry

January 2014
Supplement

Fred Khosravi and AccessClosure (C)

By: Richard Hamermesh and Lauren Barley

On September 11, 2013, the three-judge panel of the U.S. Court of Appeals for the Federal Circuit denied St. Jude's request to rehear an appeal on the "double patenting" ruling for the '439 patent. Further, it removed the injunction threat that was hanging over the... View Details

Keywords: Medical Devices; Vascular Closure Device; Patent Litigation; Patenting; Biomedical Research; Biotechnology; Biotech; Technological Innovation; Patents; Health Care and Treatment; Biotechnology Industry; United States

October 2013 (Revised January 2014)
Supplement

Fred Khosravi and AccessClosure (B)

By: Richard G. Hamermesh and Lauren Barley

It was January 2013, and Fred Khosravi, chairman of the board of AccessClosure Inc., wondered what the new year had in store for him and AccessClosure, the company he founded in late 2002. Khosravi was cautiously optimistic—the Mountain View, California-based medical... View Details

Keywords: Medical Devices; Vascular Closure Device; Patent Litigation; Patenting; Biomedical Research; Biotechnology; Biotech; Technological Innovation; Patents; Health Care and Treatment; Biotechnology Industry; United States; California

September 2024
Case

Myeloma Investment Fund

By: Kyle Myers and Scott Sawaya

This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma. The MIF, a venture philanthropy fund, must choose between two distinct paths. One option... View Details

Keywords: Venture Philanthropy; Biomedical Research; Science Bassed Business; Investing For Impact; Innovation ＆ Entrepreneurship; Venture Capital; Science-Based Business; Biotechnology Industry; Pharmaceutical Industry

12 Feb 2019
First Look

New Research and Ideas, February 12, 2019

organization theory. Theoretical consilience will enable the accumulation of empirical research into a cohesive body of knowledge on entrepreneurial resource mobilization. Publisher's link:... View Details

Keywords: Dina Gerdeman

September 2013 (Revised August 2014)
Case

Claritas Genomics

By: Robert F. Higgins and Matthew Preble

Claritas Genomics was formed in January 2013 when BCH spun out its Genetics Diagnostic Lab into a fully commercial entity. Claritas offered over 100 genomic tests to detect a range of conditions, including autism and intellectual disabilities, and was developing new... View Details

19 May 2016
Research Event

Crowdsourcing, Patent Trolls, and Other Research Insights Highlighted at Harvard Business School Symposium

said Harvard Business School Associate Professor of Business Administration Karim R. Lakhani. "The 2016 Faculty Research Symposium also looked ahead to major collaborations between Harvard’s school of business and the school of... View Details

Keywords: by Dina Gerdeman & Carmen Nobel

October 2004 (Revised March 2005)
Case

Langer Lab, The: Commercializing Science

By: H. Kent Bowen, Alex Kazaks, Ayr Muir-Harmony and Bryce LaPierre

Professor Robert Langer's laboratory at MIT is the source of an unusually large number of published papers, patents, and technology licenses to start-up and established companies in the biomedical industry. Explores Langer's leadership and other factors that create a... View Details

Keywords: Entrepreneurship; Technological Innovation; Business Startups; Research and Development; Patents; Innovation Leadership; Science-Based Business; Commercialization; Biotechnology Industry; Education Industry

June 2004 (Revised May 2005)
Case

Judah Folkman and the War on Cancer

Judah Folkman, professor in the Division of Vascular Biology at Children's Hospital in Boston, is considering how best to advance the research in his lab in an era where biomedical research has gotten more interdisciplinary and collaborative. Specifically, Folkman has... View Details

Keywords: Conflict of Interests; Leadership; Research; Personal Development and Career; Health Care and Treatment; Collaborative Innovation and Invention; Biotechnology Industry; Health Industry; Boston

18 Sep 2019
Working Paper Summaries

Female Inventors and Inventions

Keywords: by Rembrand Koning, Sampsa Samila, and John-Paul Ferguson; Health; Biotechnology; Medical Devices & Supplies

June 18, 2021
Article

Who Do We Invent for? Patents by Women Focus More on Women's Health, but Few Women Get to Invent

By: Rembrand Koning, Sampsa Samila and John-Paul Ferguson

Women engage in less commercial patenting and invention than do men, which may affect what is invented. Using text analysis of all U.S. biomedical patents filed from 1976 through 2010, we found that patents with all-female inventor teams are 35% more likely than... View Details

Keywords: Innovation; Gender Bias; Health; Innovation and Invention; Research; Patents; Gender; Prejudice and Bias

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May 2020
Article

Inventor Gender and the Direction of Invention

By: Rembrand Koning, Sampsa Samila and John-Paul Ferguson

We study whether increasing the share of female inventors leads to more biomedical inventions that focus on the needs of women. After accounting for detailed disease-technology, disease-year, and technology-year fixed effects, we find that a 10 percentage point... View Details

Keywords: Innovation and Invention; Gender; Patents