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- February 2016 (Revised September 2017)
- Case
Neurotrack and the Alzheimer's Puzzle
By: Richard G. Hamermesh, Liz Kind and Carin-Isabel Knoop
Elli Kaplan founded Neurotrack in 2012 with a breakthrough noninvasive cognitive diagnostics test that will detect Alzheimer's disease in its earliest pre-symptomatic stages. While the company has gained great traction in the three years since it was started, with no... View Details
Keywords: Alzheimer's Disease; Diagnostics; Healthcare; Entrepreneurship; Health Disorders; Science-Based Business; Business Model; Medical Devices and Supplies Industry; United States
Hamermesh, Richard G., Liz Kind, and Carin-Isabel Knoop. "Neurotrack and the Alzheimer's Puzzle." Harvard Business School Case 816-072, February 2016. (Revised September 2017.)
- May 2017
- Teaching Plan
Neurotrack and the Alzheimer's Puzzle
By: Richard G. Hamermesh and Carin-Isabel Knoop
Teaching Note for HBS No. 816-072. View Details
- 28 Sep 2020
- Working Paper Summaries
What Can Economics Say About Alzheimer's Disease?
- July 2024
- Case
Gates Ventures: Making Alzheimer's a Forgotten Past
By: Satish Tadikonda, William Marks, Shardule Shah and Calvin Marambo
After a personal journey and interest in Alzheimer's Disease (AD) by Bill Gates, Gates Ventures set out to find the best way to accelerate innovation in the field of AD. In partnership with the Alzheimer's Drug Discovery Foundation, Gates Ventures created the... View Details
Keywords: Philanthropy and Charitable Giving; Entrepreneurial Finance; Health Disorders; Mission and Purpose
Tadikonda, Satish, William Marks, Shardule Shah, and Calvin Marambo. "Gates Ventures: Making Alzheimer's a Forgotten Past." Harvard Business School Case 824-075, July 2024.
- 2020
- Working Paper
What Can Economics Say About Alzheimer's Disease?
By: Amitabh Chandra, Courtney Coile and Corina Mommaerts
Alzheimer’s Disease (AD) affects one in ten people aged 65 or older and is the most expensive disease in the United States. We describe the central economic questions raised by AD. While there is overlap with the economics of aging, the defining features of the... View Details
Chandra, Amitabh, Courtney Coile, and Corina Mommaerts. "What Can Economics Say About Alzheimer's Disease?" NBER Working Paper Series, No. 27760, August 2020.
- 02 Nov 2021
- News
Row On
Hamlin (MBA 1978), who died in May of Alzheimer’s Disease at the age of 74. Hamlin, who represented the United States in the 1968 Mexico City Olympics and at the World Rowing Championships in 1969 and 1970, continued to compete... View Details
- June 2023 (Revised July 2024)
- Case
Biogen and the Aduhelm Melee
By: Amitabh Chandra and Lauren Gunasti
Alzheimer's Disease is a devastating condition affecting millions of Americans. At this time, there is no cure. In 2021, Biogen's Aduhelm (aducanumab) received FDA approval under the accelerated approval pathway after a controversial approval process.
This... View Details
This... View Details
Keywords: Health Testing and Trials; Governing Rules, Regulations, and Reforms; Valuation; Product Development; Pharmaceutical Industry
Chandra, Amitabh, and Lauren Gunasti. "Biogen and the Aduhelm Melee." Harvard Business School Case 623-046, June 2023. (Revised July 2024.)
- February 2009
- Case
Avid Radiopharmaceuticals: The Venture Debt Question
By: Matthew Rhodes-Kropf and Ann Leamon
The CEO of a promising biotech company must decide how to respond to the macro-economic slump of late 2008. He had planned to pursue an aggressive schedule, moving the firm's Alzheimer's and Parkinson's disease imaging compounds through clinical trials and into the... View Details
Keywords: Financial Crisis; Entrepreneurship; Borrowing and Debt; Venture Capital; Financial Management; Investment; Health Testing and Trials; Expansion; Biotechnology Industry; Pharmaceutical Industry
Rhodes-Kropf, Matthew, and Ann Leamon. "Avid Radiopharmaceuticals: The Venture Debt Question." Harvard Business School Case 809-086, February 2009.
- October 2014 (Revised September 2017)
- Case
The National Football League and Brain Injuries
By: Richard G. Hamermesh and Matthew G. Preble
The National Football League (NFL) was both the most popular spectator sport in the U.S. and a major economic entity, taking in roughly $10 billion a year in revenue. However through the early twenty-first century, an increased understanding of the long-term effects of... View Details
Keywords: Employee Safety; Safety; Employees; Sports; Health; Ethics; Sports Industry; United States
Hamermesh, Richard G., and Matthew G. Preble. "The National Football League and Brain Injuries." Harvard Business School Case 815-071, October 2014. (Revised September 2017.)
- October 2012 (Revised October 2013)
- Case
Rock Health
By: Robert F. Higgins and Ian McKown Cornell
Rock Health was a San Francisco–based nonprofit organization offering accelerator services to spur innovation at the intersection of healthcare and technology. The company was the creation of Halle Tecco (HBS '11) and her HBS classmate Nate Gross (HBS '11), who met... View Details
Keywords: Innovation; Incubation; Healthcare Technology; Startups; Entrepreneurship; Innovation and Management; Health Care and Treatment; Business Startups; Health Industry; San Francisco; California; United States
Higgins, Robert F., and Ian McKown Cornell. "Rock Health." Harvard Business School Case 813-035, October 2012. (Revised October 2013.)
- June 2008 (Revised July 2008)
- Case
The Miami Project to Cure Paralysis
By: Robert Steven Kaplan, Christopher Marquis and Brent Kazan
Marc Buoniconti is the co-founder of the Miami Project to Cure Paralysis, a nonprofit medical research organization. The project was founded in 1985 by Marc and his father Nick, a former Hall of Fame football player, when Marc suffered a spinal cord injury. In 2007,... View Details
Keywords: Investment; Philanthropy and Charitable Giving; Health Testing and Trials; Leadership; Growth and Development Strategy; Mission and Purpose; Research and Development; Nonprofit Organizations; Health Industry; Miami
Kaplan, Robert Steven, Christopher Marquis, and Brent Kazan. "The Miami Project to Cure Paralysis." Harvard Business School Case 408-003, June 2008. (Revised July 2008.)
- Web
Faculty & Advisors | MBA
new therapeutic avenues through the modulation of normal biological pathways to reprogram cellular machinery through the development of de novo first-in-class compounds for neurodegenerative diseases and multiple cancers, including... View Details
- 21 Feb 2018
- Research & Ideas
When a Competitor Abandons the Market, Should You Advance or Retreat?
SolStock In late 2016 drug maker Eli Lilly announced it would stop research on the Alzheimer's drug solanezumab after results proved disappointing over three trials. For competitors such as Biogen, Merck, and Roche, this decision... View Details
- 29 May 2001
- Research & Ideas
Genomics: Can We Start Making Money Now?
about by abnormal genes, such as Alzheimer's disease or cancer. Clearly, genomics could be a gold mine for drug makers. Today, drug development is an expensive and long process—it can take up to ten years... View Details
Keywords: by Sean Silverthorne
- 07 Oct 2014
- News
Network Effect
Henry McCance, founder (left), and Tim Armour, President & CEO, of Cure Alzheimer's Fund Twelve years ago, when Henry McCance (MBA 1966) and his wife initially faced her diagnosis of Alzheimer’s disease, the couple consulted some of the... View Details
Keywords: Linda Kush
- 08 Sep 2015
- First Look
September 8, 2015
settlement in 2013, the bulk of which would go to compensating retired players suffering from such diseases as Alzheimer's or dementia. While this settlement compensated retired players, it was not... View Details
Keywords: Carmen Nobel
- 19 Dec 2024
- News
The Musts of 2024
Subscribe on iTunes Subscribe on Spotify More Skydeck episodes Hi, this is Dan Morrell, host of Skydeck. I love these end-of-the-year lists where you can get recommendations from smart people about things that are worth your time and money. It always sets me up really... View Details
- 20 Sep 2016
- First Look
September 20, 2016
School Case 816-072 Neurotrack and the Alzheimer's Puzzle Elli Kaplan founded Neurotrack in 2012 with a breakthrough noninvasive cognitive diagnostics test that will detect Alzheimer's View Details
Keywords: Sean Silverthorne
- 05 Nov 2009
- Research & Ideas
A Market for Human Cadavers in All but Name?
emergency medical workers, and medical researchers all demand cadavers or cadaver parts. As an illustration, orthopedic surgeons use human joints to fine-tune their skills to learn new procedures. Similarly, some researchers studying View Details
- 17 Mar 2009
- First Look
First Look: March 17, 2009
planned to pursue an aggressive schedule, moving the firm's Alzheimer's and Parkinson's disease imaging compounds through clinical trials and into the market. This involved expanding the firm's facilities... View Details
Keywords: Martha Lagace