Publications

Read Now

2025
Working Paper

Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance

By: Justine Boudou and Maria Roche

In this paper, we examine how a startup’s knowledge foundations—embedded in its core technology—influence its performance in the exit market. Using a dataset of 1,006 biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1) the degree of... View Details

Keywords: Firm Performance; Knowledge Foundations; Exits; Academic Startups; Inventor-founder; Specialized Scientific Knowledge; Competitive Advantage; Value Creation; Research; Information Publishing; Business Startups; Entrepreneurship

Read Now

25 Aug 2022
Research & Ideas

It’s All in a Name: Reputable Investors Help Startups Shine

Do top venture capital firms add value to startups simply by attaching their names? If attracting talent is any measure, they sure do. New research finds that job seekers are two-thirds more likely to apply to a View Details

Keywords: by Rachel Layne

September 2020
Case

Disrupting Justice at RightNow: Rich or King

By: Shikhar Ghosh and Amir Reza Rezvani

The case examines issues such as cascading problems within the organization, changing founder roles, founder success criteria, as well as company exit consideration. In 2017, Dr. Torben Antretter, a former competitive tennis player and academic researcher, founded... View Details

Keywords: Exit; Startup; Financing; Founders; Entrepreneurship; Law; Venture Capital; Success; Financing and Loans; Business Growth and Maturation; Strategy; Legal Services Industry; Germany

May 2020 (Revised July 2020)
Case

Justice-as-a-Service at RightNow

By: Shikhar Ghosh and Amir Reza Rezvani

The case examines the focus of an early stage company, and how an unexpected external incidence can threaten or void the business model. It encompasses issues such as minimal viable product, defining and pivoting a business model, organizational requirements for a... View Details

Keywords: Legacy Business; Teams; Startup; Business Models; Pivot; Entrepreneurship; Law; Venture Capital; Business Startups; Business Model; Organizational Change and Adaptation; Strategy; Legal Services Industry; Germany

September 2020
Case

Disrupting Justice at RightNow: Persevere, Pivot or Perish

By: Shikhar Ghosh and Amir Reza Rezvani

The case examines the focus of an early stage company, and how an unexpected external incidence can threaten or void the business model. It encompasses issues such as defining and pivoting a business model, organizational requirements for a pivot, investor relations,... View Details

Keywords: Legal Aspects Of Business; Startup; Teams; Pivot; Financing; Entrepreneurship; Law; Venture Capital; Business Startups; Financing and Loans; Business Model; Organizational Change and Adaptation; Legal Services Industry; Germany

September 2019 (Revised May 2021)
Case

pymetrics: Early Days

By: John R. Wells and Benjamin Weinstock

In 2013, CEO Frida Polli was contemplating the next steps for her start-up business, pymetrics. After receiving her PhD in neuropsychology and MBA from HBS, she was determined to put her scientific and academic knowledge to work to build a business solving real world... View Details

August 2023 (Revised January 2024)
Case

Three Vignettes of Early Careers in the Life Sciences

By: Satish Tadikonda, Jacqueline Grant and William Marks

The case showcases three vignettes of career choice scenarios facing new graduates. How one navigates and handles these situations can have a significant impact on careers overall, with each vignette representing a situation likely to be experienced by most students in... View Details

Research Summary

Institutions and Innovation

Henry Chesbrough's research interests lie at the intersection of organizations and innovation. His research to date falls into two tracks.

The first track examines the effect of the firm's institutional environment upon its ability to respond to innovation... View Details

26 Aug 2013
Lessons from the Classroom

Built for Global Competition from the Start

Thanks to the Internet, entrepreneurs are no longer confined to a local geography when building a new business—the world can be their market from day one. But building a startup as a global business requires managers with skills and... View Details

Keywords: by Kim Girard; Education

September 2024
Case

Myeloma Investment Fund

By: Kyle Myers and Scott Sawaya

This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.

The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details

Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation ＆ Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry

2024
Working Paper

The Wandering Scholars: Understanding the Heterogeneity of University Commercialization

By: Josh Lerner, Henry Manley, Carolyn Stein and Heidi Williams

University-based scientific research has long been argued to be a central source of commercial innovation and economic growth. Yet at the same time, there have been long-held concerns that many university-based discoveries never realize their potential social... View Details

Keywords: Research; Higher Education; Business Startups; Innovation and Invention

Read Now

26 Jul 2024
Research & Ideas

Why Great Ideas Get Stuck in Universities

affected by interest rate-related volatility in venture capital funding and mergers and acquisitions activity. Roche conducted the analysis with Justine Boudou, a doctoral student at HBS. Academic chops don’t translate to success The 510... View Details

Keywords: by Ben Rand; Biotechnology; Health

16 Sep 2015
Research & Ideas

Can Applied Economics Save Homeless Puppies?

matching system for New England, correcting public school choice programs in New York and Boston, and tackling markets for new medical residents, economists, and lawyers. That same year, Christine L. Exley and Elena Battles launched a View Details

Keywords: by Carmen Nobel; Retail

2003
Chapter

Equity Financing

By: Paul Gompers and Joshua Lerner

Equity financing for entrepreneurial firms has attracted increasing attention in both the popular press and academic literature. The dramatic growth in the venture capital industry in the past two decades has been accompanied by new academic research that explores... View Details

Keywords: Angel Investors; Financing and Loans; Equity; Venture Capital; Business Startups

October 2023 (Revised November 2023)
Case

Rheaply: Circularity For Every Business

By: Rembrand Koning and Alicia Dadlani

In March 2023, Garry Cooper, cofounder and CEO of Chicago-based Rheaply, needed to demonstrate that Rheaply’s expanded vision could translate into building cash flows and metrics needed to raise a Series B and turn the business into a model for financial and... View Details

Keywords: Business Startups; Social Entrepreneurship; Technological Innovation; Environmental Sustainability; Entrepreneurial Finance; Technology Industry; Green Technology Industry; United States; Illinois; Chicago

August 2007 (Revised July 2008)
Background Note

Take Advantage of Your Diaspora Network

By: William R. Kerr and Daniel J. Isenberg

Diaspora networks (DNs) are an important resource for global entrepreneurs. Discusses several features of DNs, combining both academic and practitioner perspectives. Describes the history and prevalence of DNs in many ethnicities, documents the broad resources DNs can... View Details

Keywords: Business Startups; Diasporas; Entrepreneurship; Globalized Markets and Industries; Social and Collaborative Networks

June 2016 (Revised December 2017)
Case

The Cheese and the Oligarchs: The Politics, the Media, and Israel's Dream of a Start-Up Nation

By: Rafael Di Tella and Christine Snively

Israel enjoyed the highest concentration of technology start-ups in the world per capita. Despite regional instability, the country maintained strong economic growth and was considered a high-tech powerhouse. But not all Israelis benefited. Between the 1980s and 2010s,... View Details

Keywords: Entrepreneurship; Information Technology; Business Conglomerates; Business Startups; Israel

June 2016
Teaching Note

The Cheese and the Oligarchs: The Politics, the Media, and Israel's Dream of a Start-Up Nation

By: Rafael Di Tella and Christine Snively

Israel enjoyed the highest concentration of technology start-ups in the world per capita. Despite regional instability, the country maintained strong economic growth and was considered a high-tech powerhouse. But not all Israelis benefited. Between the 1980s and 2010s,... View Details

Keywords: Entrepreneurship; Information Technology; Business Conglomerates; Business Startups; Israel