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- July 2023
- Case
DayTwo: Going to Market with Gut Microbiome (Abridged)
By: Ayelet Israeli
DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
- July 2023 (Revised July 2024)
- Case
Miracle Therapeutics: Negotiating an IP License (A)
By: Satish Tadikonda, Michael Singer, William Marks and Wendi Yajnik
(General Experience Case) Beth Sharp and Jennifer Brilliant founded Miracle Therapeutics based on intellectual property developed by Brilliant and her post-doctoral student, John Supreme, in Brilliant’s lab at Elite University (EU). Miracle will have to obtain a... View Details
- 18 Jul 2023
- Interview
Jeffrey Rayport on Product Market Fit, Profit Market Fit and Whiplash, and More
By: Jeffrey F. Rayport and Doug Levin
This episode of "Lessons from Startup Life" podcast features Jeffrey Rayport, Senior Lecturer of Business Administration at the Harvard Business School. Jeffrey specializes in teaching and researching growth-stage technology ventures and their scalability. Prior to... View Details
- July–August 2023
- Article
Case Study: How Should a Start-Up Cut Its Burn Rate?
By: Nitin Nohria, Katie Josephson, Sophia Wronsky and Elizabeth Rha
Tyler Smith, the founder and CEO of the enterprise software firm Puck.io, is facing a hard decision. Just three months earlier the company laid off 20% of its employees to reduce its burn rate amid growing economic uncertainty and a suddenly unattractive funding... View Details
- June 30, 2023
- Article
How to Save a Stumbling Startup
By: Ranjay Gulati
- June 19, 2023
- Article
Should You Start a Generative AI Company?
Many entrepreneurs are considering starting companies that leverage the latest generative AI technology, but they must ask themselves whether they have what it takes to compete on increasingly commoditized foundational models, or whether they should instead... View Details
- June 2023 (Revised November 2023)
- Case
Sober Sidekick
By: Jeffrey J. Bussgang and Kumba Sennaar
Case on the nascent business model of a mobile health IT startup. In particular, should they pivot away from their successful lead generation business model to charging health plans. View Details
- May–June 2023
- Article
Should Your Start-up Be For-profit or Nonprofit?: A Guide for Social Entrepreneurs
By: Cait Brumme and Brian Trelstad
Years ago the line between nonprofit and for-profit enterprises was clear, but that has changed. Nonprofits now offer products that compete with those of the best for-profits, and for-profits can deliver as much social value as charities. Despite the blurred... View Details
- April 2023 (Revised September 2023)
- Case
Levels: The Remote, Asynchronous, Deep Work Management System
By: Joseph B. Fuller and George Gonzalez
Levels is a highly innovative startup in the health care space. They intend to revolutionize health by linking behavior—eating, exercise, sleeping, etc.—to changes in metabolism. They believe metabolic health can be managed through careful monitoring of changes in... View Details
- April 2023
- Case
Drive Capital: A New Road for Venture
By: Paul A. Gompers and Alicia Dadlani
Founded by two former Sequoia Capital partners, Columbus-Ohio-based Drive Capital’s mission was to build a world-class venture capital firm in the middle of the U.S., an area historically overlooked by VCs. Drive faced early challenges of attracting investors, sourcing... View Details
- March 2023
- Teaching Note
VideaHealth: Building the AI Factory
By: Karim R. Lakhani
Teaching Note for HBS Case No. 621-021. The case “VideaHealth: Building the AI Factory” examines the creation of dental startup VideaHealth (Videa) and the development of its artificial intelligence (AI)-led business strategy through the eyes of founder and CEO Florian... View Details
- March 24, 2023
- Article
What Silicon Valley Bank Did Right
By: Lou Shipley
There’s a reason Silicon Valley Bank became such a fixture among startups: it understood their needs better than any other bank. Even now, many banks don’t have the flexibility and understanding to make banking easy for startups. With SVB gone, a lot of young companies... View Details
- March 2023
- Case
Mirakl: Growing The Marketplace Economy
By: Antonio Moreno, Santiago Gallino and Emilie Billaud
Mirakl provided the technology and seller network required for companies like Macy's, Best Buy, Walmart, Siemens, or Carrefour to simply design, launch, and administer a marketplace that included products from third-party sellers. What began as a basic business idea in... View Details
- March 2023
- Case
FinTunes, Inc., Board of Directors
By: Lynn S. Paine and Jennifer Fonstad
The board of FinTunes, Inc., a start-up aimed at helping musicians distribute their work and manage their finances, must decide among three candidates to serve as the company’s first independent director. The terms of FinTunes’ last round of financing provided that the... View Details
- March 2023 (Revised June 2023)
- Case
Doing Business in Kigali, Rwanda
By: Andy Zelleke, A. Zelleke, Leonard A. Schlesinger, Leonard A. Schlesinger, Pippa Tubman Armerding and Wale Lawal
This case examines the challenges and opportunities of doing business in Rwanda. It highlights Rwanda's economic transformation in the decades leading up to 2023 in the context of its history, culture, and politics. The case gives an overview of some of the main... View Details
- March 2023 (Revised May 2025)
- Case
On (A)
By: Ramon Casadesus-Masanell, Karolin Frankenberger and Sascha Mader
Founded in 2010, in just one decade, the Swiss company On had established itself as a main player in global sports footwear and apparel. Based on an unconventional strategy which one of the founders labeled as “obsessively distinct,” On grew its sales with a compound... View Details
Keywords: Brands and Branding; Business Growth and Maturation; Business Model; Business Startups; Business Strategy; Competitive Advantage; Competitive Strategy; Corporate Strategy; Customer Focus and Relationships; Customer Satisfaction; Digital Marketing; Disruptive Innovation; Distribution Channels; Entrepreneurship; Environmental Sustainability; Global Strategy; Initial Public Offering; Innovation and Invention; Innovation Strategy; Market Entry and Exit; Marketing Strategy; Product Design; Product Development; Product Marketing; Social Media; Strategy; Supply Chain Management; Technological Innovation; Apparel and Accessories Industry; Consumer Products Industry; Manufacturing Industry; Retail Industry; Sports Industry; Europe; Switzerland; Germany; United States
- February 2023
- Case
Enstitute
By: Lindsay N. Hyde, Thomas R. Eisenmann, Kumba Sennaar and Sarah Mehta
Shaila Ittycheria (MBA ’10) founded the nonprofit organization Enstitute, in 2012 in New York City. Determined to challenge the status quo within higher education, Shaila and her cofounder sought to expand opportunities for talented young people by placing them in... View Details
- February 2023
- Case
Kapor Capital
By: Jeffrey J. Bussgang, Lindsay N. Hyde and Julia Kelley
Kapor Capital, a leading impact investment venture capital (VC) firm, is on the cusp of a generational transition. The two rising managing directors are about to take over the firm from the VC’s eponymous founders. How should they think about strategy, brand, and... View Details
- February 2023
- Supplement
Astyanax Kanakakis at norbloc: A Founder's Experience with the DIFC Fintech Hive
By: Linda A. Hill and Lydia Begag
norbloc was founded in 2016 in Stockholm, Sweden, by Astyanax Kanakakis and his co-founders, Vitalii Demianets and Sam Saatchi. Kanakakis and Demianets got to work to address a key gap in the industry: Know Your Customer (KYC) data sharing. As the first distributed KYC... View Details
Keywords: Organizational Change and Adaptation; Organizational Design; Organizational Culture; Organizational Structure; Organizations; Leadership; Leadership Development; Leadership Style; Collaborative Innovation and Invention; Digital Transformation; Digital Strategy; Digital Platforms; Technology Adoption; Technological Innovation; Corporate Entrepreneurship; Business and Government Relations; Business Startups; Financial Services Industry; Technology Industry; Banking Industry; Information Technology Industry; Sweden; Europe; Singapore; London; United Arab Emirates; Dubai; Middle East; Athens; Greece
- February 2023
- Case
Nexus Market (A): Ukraine War Ripples into Silicon Valley
By: Tsedal Neeley and Jeff Huizinga
A Silicon Valley start-up executive must navigate tensions between its Ukrainian and Russian sub-contractors as war between the two countries rages. After war erupts between Ukraine and Russia, a team of subcontracted Ukrainian software developers threatens to cut ties... View Details